Professor Jason King - 'A universal model for macropinocytosis and organising large actin structures'
1:00pm - 2:00pm /
Thursday 4th December 2025
/ Venue: Physiology seminar room Nuffield Wing
Type: Seminar /
Category: Research
/ Series: Institute of Systems, Molecular and Integrative Biology
- ISMIB Seminar Team
- Admission: Free, no registration required.
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Jason King is Professor of Cell Biology at the University of Sheffield, where he has led a research group since 2013. His group are preoccupied with how cells eat and drink, using the sister processes of phagocytosis and macropinocytosis respectively. Their aim is to understand both how the actin cytoskeleton is regulated to allow engulfment, as well as the endocytic trafficking mechanisms used to process internalised material. These pathways are used by cells to fulfil many different roles, so studies range from fundamental biology to host-pathogen interactions and cancer metabolism. The focus of this talk will be recent work on a new biophysical model for how macropinocytic structures are generated and close to allow cells to feed on extracellular proteins.