About us

COVID-19 patients frequently suffer brain problems during the infection and can be left with symptoms of brain injury. Similar problems have been seen in previous pandemics, including Spanish influenza over 100 years ago, but how and why this occurs is poorly understood.

What is the study?

We have already been notified of 800 UK patients with these complications due to COVID-19. We have a unique opportunity to understand how these problems occur and develop strategies to prevent and treat them.

The questions we will ask include in whom does COVID-19 cause injury? Does it do this by invading the brain? Or by triggering excessive immune responses or interfering with the blood supply to nervous tissue?

We will answer these questions through in-depth clinical, laboratory, and imaging studies of these 800 patients in comparison to 500 control patients (hospitalised during the pandemic with COVID-19 [400] or without COVID-19 [100]).

Without this understanding, we cannot determine whether anti-viral medication or treatments that modulate the immune system or that improve blood supply will help, and if so in which patients.

We will apply this understanding through our World Health Organisation-commissioned Task Force (co-Chair Dr Ben Michael) to develop clinical care guidelines, identify patients for targeted clinical trials, and ultimately improve patient outcomes.

How can I get involved?

If you are a patient that is interested in joining the study, see our patient section and learn more about how to self-refer onto the study and what is involved.

If you already have a patient and need to begin the patient consultation then visit our recruitment website, you will need your username and password to log in.

Back to: COVID-19 Clinical Neuroscience Study (COVID-CNS)