Our team

We are a team of multidisciplinary scientists working in different areas of research.

Director

Back to: Computational Biology Facility

Professor Andy Jones

Professor Andy Jones

Andy is a specialist in proteome informatics and post genomic science. His particular areas of interest include new algorithms and software, databases, data sharing, and the interface between different types of Omics data. He has a strong track record in developing software and data standards for mass spectrometry (proteomics and metabolomics), and has developed popular databases in immunogenetics. For more details please visit Andy's professional profile.

 


Associated directors

Dan Rigden

Professor Dan Rigden

Dan is a specialist in protein sequence and structural bioinformatics. He is particularly interested in using 3D modelling of all kinds to understand, predict and redesign protein catalysis, specificity and interactions. He is equally enthused by cryptic genome sequences and well-characterised proteins of medical or industrial relevance.


Portrait of Dr Jamie Soul CBF

Dr Jamie Soul

Jamie has recently joined the University as a Senior Data Scientist following a Versus Arthritis Fellowship at Newcastle University. He has eight years of bioinformatics experience and a broad range of skills, with a strong interest in developing and applying new computational approaches to biomedical data to drive hypothesis generation. He enjoys learning new areas of biology and is excited by the potential of emerging technologies such as single-cell sequencing, spatial transcriptomics and high-throughput functional genomics (CRISPR screens).

 


Management and leadership

Eva Caamaño-Gutiérrez

Dr Eva Caamaño-Gutiérrez - Facility Manager and Data Scientist

As our manager, Eva coordinates all our work. She is a scientist by training and holds a PhD in Systems Biology. She has broad experience in data integration and her interests lie in application-based and translational biology.

Eva has led the creation and deployment of our most popular courses R for beginners and R for data science. She enjoys teaching and talking about different scientific projects. Have a look to her full profile here.

 


John Heap

John Heap – Senior Software Engineer and Deputy Facility Manager

John has over 20 years of industry experience developing various pipelines and solutions for life sciences. He is working on an assortment of projects including the use of social media to improve determination of adverse effect of commercialised drugs. He has had a key role in COVID-19 response projects such as Symptom Watch and Campus Shield.


Data Scientists and Software Engineers

Arturas Grauslys

Dr Arturas Grauslys – Data Scientist

Arturas joined the Facility after completing a short post-doctoral position developing NMR metabolomics software. He is most interested in computational statistics and machine learning. He has worked with biological networks with the aim to classify compounds’ modes of action and currently is working on a number of health data science projects applying machine learning to solve complex problems with high impact in patient care.

He has co-develop the courses R for beginners and R for data science and supports a number of students learning R.


Dr Anthony Evans - Data Scientist

Anthony joined the Facility following a post-doctoral position, investigating biomarkers for therapeutic response in pancreatic cancer. He has particular interests in understanding disease heterogeneity and applying computational biology for clinical benefit.

 


Dr Emily Johnson - Data Scientist

Emily joined the CBF as a data scientist following a PhD where she used a systems biology approach to study type I collagen regulation in ageing and disease. She has previous experience as a database curator. Her primary interests are integrating multi-omics data, systems modelling, molecular modelling and how these techniques can be applied to translational biology.

 


Dr Antony McCabe

Dr Antony McCabe - Senior Software Engineer

Tony is a computer scientist with wide experience in software development and database creation. He is currently working on a number of different bioinformatic software projects. This includes the Allele Frequencies Net Database, the ChannelBank prototype as well as in-house software for research purposes and data visualisation.


Dr Kerry Ramsbottom – Data Scientist

Kerry joined the CBF as a part-time data scientist alongside a post-doctoral position where she is working on a project aimed to develop statistical methods for PTM localisation and create gold standard data sets for human and model organisms. Her other work has included informatics investigations to explore the involvement of Human Leukocyte Antigens (HLA) with adverse drug reactions.

 


Portrait of Alex Rothwell

Alex Rothwell – Data Scientist

Alex joined the CBF while completing his PhD in machine learning for improving blood cancer diagnosis, working with the Haemato-Oncology Diagnostics Service (HODS) based at the Royal Liverpool University Hospital. His other work includes using interpretable machine learning to predict and understand factors affecting kidney transplant rejection, and working with Alder Hey Children's Hospital to improve management of neuromuscular disorders.

 

Honorary Staff

Kim Clarke

Dr Kim Clarke - Associate Principal Informatician at Astra Zeneca

Kim joined the CBF as a full-time data analyst after a post-doctoral position investigating the molecular drivers of metastasis in renal tumours. In his time in the CBF he specialised in applying multi-omics based strategies to issues of human health and diseases and  the development of novel approaches to analyse single cell transcriptomics data. Kim is now a senior data scientist in Astra Zeneca and holds an honorary position with us. 


Mr Daniel Green – Data Scientist

Dan worked at the CBF while undertaking a MRC/Versus Arthritis PhD developing models to identify biomarkers for age and disease in musculoskeletal tissues. His experience resides in genome wide epigenetic, epi-transcriptomic and gene expression analysis with a particular interest in applying statistical/machine learning approaches to answer biological questions. Dan is now a senior data scientist at Mitra Bio and continues a close collaboration with the CBF

 


Francesco Falciani

Honorary Professor Francesco Falciani

Francesco is a specialist in developing novel computational approaches in systems biology and the application of these techniques to complex biological systems. Projects in Francesco’s research group have ranged from modelling the effect of pollutants in the environment to cancer and ageing. He was very involved in the Systems Medicine efforts in the MRC Centre for Drug Safety Science and in the area of blood malignancies.

Francesco has recently left the university to focus on his consultancy work but remains a great source of advice and inspiration for our work. 

 


Philipp Antczak

Dr Philipp Antczak

Philipp has now moved to the University of Cologne in Germany but remains closely associated with the CBF. He has a well-established track record of developing and applying computational tools to areas of biomedical and environmental science. He has experience utilising statistical/predictive/network modelling approaches, data integration techniques, and machine learning to answer biological questions. His main focus is in understanding the molecular basis underlying stress responses/adaptation in acute, chronic or transgenerational observed effects.


Alumni

  • Mr Simon Perkins - Currently working as Principal Informatician in Astra Zeneca
  • Dr Mara Kozic - Bioinformatics analyst in DIOSynVax
  • Dr Louise Yukari Takeshita 
  • Mr John Herbert - freelance bioinformatician