Research outputs
2025
Nanoelectrospray fabrication of pH-responsive double-layered drug-eluting contact lenses for ocular drug delivery.
Bebawy, G., Sanderson, J., & Qi, S. (2025). Nanoelectrospray fabrication of pH-responsive double-layered drug-eluting contact lenses for ocular drug delivery.. International journal of pharmaceutics, 686, 126323. doi:10.1016/j.ijpharm.2025.126323
Development and Evaluation of Anti-Pollution Film-Forming Facial Spray Containing Coffee Cherry Pulp Extract.
Preedalikit, W., Chittasupho, C., Leelapornpisid, P., Qi, S., & Kiattisin, K. (2025). Development and Evaluation of Anti-Pollution Film-Forming Facial Spray Containing Coffee Cherry Pulp Extract.. Pharmaceutics, 17(3), 360. doi:10.3390/pharmaceutics17030360
4D printing of shape-memory polymer-based floating tablets via fused deposition modelling: Transformable helical structure to tablet-like form
Panraksa, P., Hamdallah, S. I., Yilmaz, O., Saokham, P., Rachtanapun, P., Qi, S., & Jantrawut, P. (2025). 4D printing of shape-memory polymer-based floating tablets via fused deposition modelling: Transformable helical structure to tablet-like form. Journal of Drug Delivery Science and Technology, 104, 106534. doi:10.1016/j.jddst.2024.106534
Can we create customized polypills for personalized drug formulation?
Qi, S. (2025). Can we create customized polypills for personalized drug formulation?. Expert opinion on drug delivery, 22(7), 915-918. doi:10.1080/17425247.2025.2498650
High-precision deposition and controlled release of high molecular weight hyaluronic acid from contact lens surfaces using nanoelectrospray
Tiwari, R., Alexander, M., Sanderson, J., Broad, R. A., Peng, C. -C., Jani, D., & Qi, S. (2026). High-precision deposition and controlled release of high molecular weight hyaluronic acid from contact lens surfaces using nanoelectrospray. RSC Pharmaceutics. doi:10.1039/d5pm00237k
Technology, pharmacology, and clinical outcomes of sirolimus coated balloons for peripheral arterial interventions.
Khonkarn, R., Ramadani, P., Qi, S., Ali, T., & Krokidis, M. (2025). Technology, pharmacology, and clinical outcomes of sirolimus coated balloons for peripheral arterial interventions.. Expert review of medical devices, 22(12), 1369-1378. doi:10.1080/17434440.2025.2574364
2024
Using a systematic and quantitative approach to generate new insights into drug loading of PLGA nanoparticles using nanoprecipitation.
Hamdallah, S. I., Zoqlam, R., Yang, B., Campbell, A., Booth, R., Booth, J., . . . Qi, S. (2024). Using a systematic and quantitative approach to generate new insights into drug loading of PLGA nanoparticles using nanoprecipitation.. Nanoscale advances, 6(12), 3188-3198. doi:10.1039/d4na00087k
Selectively coated contact lenses by nanoelectrospray (nES) to fabricate drug-eluting contact lenses for treating ocular diseases.
Tam, C. H., Alexander, M. S., Sanderson, J., & Qi, S. (2024). Selectively coated contact lenses by nanoelectrospray (nES) to fabricate drug-eluting contact lenses for treating ocular diseases.. Medical engineering & physics, 124, 104110. doi:10.1016/j.medengphy.2024.104110
3D Printing of Pharmaceutical and Drug Delivery Devices: Progress from Bench to Bedside
Lamprou, D. A., Douroumis, D., & Qi, S. (2024). 3D Printing of Pharmaceutical and Drug Delivery Devices: Progress from Bench to Bedside.
Advances in Pharmaceutical Technology: Series Preface
Lamprou, D. A., Douroumis, D., & Qi, S. (2024). Advances in Pharmaceutical Technology: Series Preface. 3D Printing of Pharmaceutical and Drug Delivery Devices Progress from Bench to Bedside, xxi-xxii.
Materials for 3D Printing
McDonagh, T., Zhang, B., & Qi, S. (2024). Materials for 3D Printing. In 3D Printing of Pharmaceutical and Drug Delivery Devices Progress from Bench to Bedside (pp. 1).
Preface
Lamprou, D. A., Douroumis, D., & Qi, S. (2024). Preface. 3D Printing of Pharmaceutical and Drug Delivery Devices Progress from Bench to Bedside, xxiii-xxiv.
The Use of Microstructure Design and 3D Printing for Tailored Drug Release
Zhang, B., McDonagh, T., Yan, J., Glendale, A., Bib, R., Belton, P., & Qi, S. (2024). The Use of Microstructure Design and 3D Printing for Tailored Drug Release. In 3D Printing of Pharmaceutical and Drug Delivery Devices Progress from Bench to Bedside (pp. 29-42).
2023
An investigation into the effects of ink formulations of semi-solid extrusion 3D printing on the performance of printed solid dosage forms.
Zhang, B., Belton, P., Teoh, X. Y., Gleadall, A., Bibb, R., & Qi, S. (2023). An investigation into the effects of ink formulations of semi-solid extrusion 3D printing on the performance of printed solid dosage forms.. Journal of materials chemistry. B, 12(1), 131-144. doi:10.1039/d3tb01868g
Manipulating drug release from 3D printed dual-drug loaded polypills using challenging polymer compositions.
McDonagh, T., Belton, P., & Qi, S. (2023). Manipulating drug release from 3D printed dual-drug loaded polypills using challenging polymer compositions.. International journal of pharmaceutics, 637, 122895. doi:10.1016/j.ijpharm.2023.122895
Interaction of polymers with bile salts - Impact on solubilisation and absorption of poorly water-soluble drugs.
Pigliacelli, C., Belton, P., Wilde, P., Bombelli, F. B., Kroon, P. A., Winterbone, M. S., & Qi, S. (2023). Interaction of polymers with bile salts - Impact on solubilisation and absorption of poorly water-soluble drugs.. Colloids and surfaces. B, Biointerfaces, 222, 113044. doi:10.1016/j.colsurfb.2022.113044
2022
Lipid based intramuscular long-acting injectables: Current state of the art.
Wilkinson, J., Ajulo, D., Tamburrini, V., Gall, G. L., Kimpe, K., Holm, R., . . . Qi, S. (2022). Lipid based intramuscular long-acting injectables: Current state of the art.. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 178, 106253. doi:10.1016/j.ejps.2022.106253
Development of combi-pills using the coupling of semi-solid syringe extrusion 3D printing with fused deposition modelling.
Zhang, B., Teoh, X. Y., Yan, J., Gleadall, A., Belton, P., Bibb, R., & Qi, S. (2022). Development of combi-pills using the coupling of semi-solid syringe extrusion 3D printing with fused deposition modelling.. International journal of pharmaceutics, 625, 122140. doi:10.1016/j.ijpharm.2022.122140
An investigation into the effects of geometric scaling and pore structure on drug dose and release of 3D printed solid dosage forms.
McDonagh, T., Belton, P., & Qi, S. (2022). An investigation into the effects of geometric scaling and pore structure on drug dose and release of 3D printed solid dosage forms.. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 177, 113-125. doi:10.1016/j.ejpb.2022.06.013
Precision coating of ocular devices/contact lenses by nanoelectrospray additive printing
Tam, C. H., Alexander, M. S., & Qi, S. (2022). Precision coating of ocular devices/contact lenses by nanoelectrospray additive printing. Materials & Design, 219, 110782. doi:10.1016/j.matdes.2022.110782
Emerging molecular mechanisms and genetic targets for developing novel therapeutic strategies for treating bladder diseases.
Zoqlam, R., Lazauskaite, S., Glickman, S., Zaitseva, L., Ilie, P. -C., & Qi, S. (2022). Emerging molecular mechanisms and genetic targets for developing novel therapeutic strategies for treating bladder diseases.. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 173, 106167. doi:10.1016/j.ejps.2022.106167
The Effects of Solid Particle Containing Inks on the Printing Quality of Porous Pharmaceutical Structures Fabricated by 3D Semi-Solid Extrusion Printing.
Teoh, X. -Y., Zhang, B., Belton, P., Chan, S. -Y., & Qi, S. (2022). The Effects of Solid Particle Containing Inks on the Printing Quality of Porous Pharmaceutical Structures Fabricated by 3D Semi-Solid Extrusion Printing.. Pharmaceutical research, 39(6), 1267-1279. doi:10.1007/s11095-022-03299-7
Direct Granule Feeding of Thermal Droplet Deposition 3D Printing of Porous Pharmaceutical Solid Dosage Forms Free of Plasticisers.
McDonagh, T., Belton, P., & Qi, S. (2022). Direct Granule Feeding of Thermal Droplet Deposition 3D Printing of Porous Pharmaceutical Solid Dosage Forms Free of Plasticisers.. Pharmaceutical research, 39(3), 599-610. doi:10.1007/s11095-022-03198-x
'Tablet-in-Syringe': A Novel Dosing Mechanism for Dysphagic Patients Containing Fast-Disintegrating Tablets Fabricated Using Semisolid Extrusion 3D Printing.
Panraksa, P., Zhang, B., Rachtanapun, P., Jantanasakulwong, K., Qi, S., & Jantrawut, P. (2022). 'Tablet-in-Syringe': A Novel Dosing Mechanism for Dysphagic Patients Containing Fast-Disintegrating Tablets Fabricated Using Semisolid Extrusion 3D Printing.. Pharmaceutics, 14(2), 443. doi:10.3390/pharmaceutics14020443
Effect of printing parameters on microscale geometry for 3D printed lattice structures
Kayali, Y., Ding, M., Hamdallah, S., Qi, S., Bibb, R., & Gleadall, A. (2022). Effect of printing parameters on microscale geometry for 3D printed lattice structures. In Materials Today: Proceedings Vol. 70 (pp. 31-37). Elsevier BV. doi:10.1016/j.matpr.2022.08.487
2021
Drop-on-demand printing of personalised orodispersible films fabricated by precision micro-dispensing.
Tam, C. H., Alexander, M., Belton, P., & Qi, S. (2021). Drop-on-demand printing of personalised orodispersible films fabricated by precision micro-dispensing.. International journal of pharmaceutics, 610, 121279. doi:10.1016/j.ijpharm.2021.121279
CHAPTER 11: Three-dimensional Printed Implantable Products
Qi, S., Zhang, B., & McDonagh, T. (2021). CHAPTER 11: Three-dimensional Printed Implantable Products. In V. Srivastava (Ed.), Implantable Technologies Peptides and Small Molecules Drug Delivery. Royal Society of Chemistry.
Characterization of Hydrophilic Polymers as a Syringe Extrusion 3D Printing Material for Orodispersible Film.
Panraksa, P., Qi, S., Udomsom, S., Tipduangta, P., Rachtanapun, P., Jantanasakulwong, K., & Jantrawut, P. (2021). Characterization of Hydrophilic Polymers as a Syringe Extrusion 3D Printing Material for Orodispersible Film.. Polymers, 13(20), 3454. doi:10.3390/polym13203454
New insights into the effects of porosity, pore length, pore shape and pore alignment on drug release from extrusionbased additive manufactured pharmaceuticals
Zhang, B., Gleadall, A., Belton, P., Mcdonagh, T., Bibb, R., & Qi, S. (2021). New insights into the effects of porosity, pore length, pore shape and pore alignment on drug release from extrusionbased additive manufactured pharmaceuticals. Additive Manufacturing, 46, 102196. doi:10.1016/j.addma.2021.102196
Evaluation of the Benefits of Microfluidic-Assisted Preparation of Polymeric Nanoparticles for DNA Delivery.
Zoqlam, R., Morris, C. J., Akbar, M., Alkilany, A. M., Hamdallah, S. I., Belton, P., & Qi, S. (2021). Evaluation of the Benefits of Microfluidic-Assisted Preparation of Polymeric Nanoparticles for DNA Delivery.. Materials science & engineering. C, Materials for biological applications, 127, 112243. doi:10.1016/j.msec.2021.112243
Effects of porosity on drug release kinetics of swellable and erodible porous pharmaceutical solid dosage forms fabricated by hot melt droplet deposition 3D printing.
Zhang, B., Nasereddin, J., McDonagh, T., von Zeppelin, D., Gleadall, A., Alqahtani, F., . . . Qi, S. (2021). Effects of porosity on drug release kinetics of swellable and erodible porous pharmaceutical solid dosage forms fabricated by hot melt droplet deposition 3D printing.. International journal of pharmaceutics, 604, 120626. doi:10.1016/j.ijpharm.2021.120626
The use of polymer blends to improve stability and performance of electrospun solid dispersions: The role of miscibility and phase separation.
Tipduangta, P., Belton, P., McAuley, W. J., & Qi, S. (2021). The use of polymer blends to improve stability and performance of electrospun solid dispersions: The role of miscibility and phase separation.. International journal of pharmaceutics, 602, 120637. doi:10.1016/j.ijpharm.2021.120637
Suppression of the coffee-ring effect by tailoring the viscosity of pharmaceutical sessile drops
Wilkinson, J., Tam, C., Askounis, A., & Qi, S. (2021). Suppression of the coffee-ring effect by tailoring the viscosity of pharmaceutical sessile drops. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 614, 126144. doi:10.1016/j.colsurfa.2021.126144
2020
An investigation into the formations of the internal microstructures of solid dispersions prepared by hot melt extrusion.
Alqahtani, F., Belton, P., Zhang, B., Al-Sharabi, M., Ross, S., Mithu, M. S. H., . . . Qi, S. (2020). An investigation into the formations of the internal microstructures of solid dispersions prepared by hot melt extrusion.. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 155, 147-161. doi:10.1016/j.ejpb.2020.08.018
Hot melt extruded zein for controlled delivery of diclofenac sodium: Effect of drug loading and medium composition.
Bisharat, L., Alkhatib, H. S., Abdelhafez, A., Barqawi, A., Aljaberi, A., Qi, S., & Berardi, A. (2020). Hot melt extruded zein for controlled delivery of diclofenac sodium: Effect of drug loading and medium composition.. International journal of pharmaceutics, 585, 119503. doi:10.1016/j.ijpharm.2020.119503
Microfluidics for pharmaceutical nanoparticle fabrication: The truth and the myth.
Hamdallah, S. I., Zoqlam, R., Erfle, P., Blyth, M., Alkilany, A. M., Dietzel, A., & Qi, S. (2020). Microfluidics for pharmaceutical nanoparticle fabrication: The truth and the myth.. International journal of pharmaceutics, 584, 119408. doi:10.1016/j.ijpharm.2020.119408
Automation Potential of a New, Rapid, Microscopy-Based Method for Screening Drug-Polymer Solubility.
Alhijjaj, M., Belton, P., Fabian, L., Reading, M., & Qi, S. (2020). Automation Potential of a New, Rapid, Microscopy-Based Method for Screening Drug-Polymer Solubility.. ACS omega, 5(20), 11402-11410. doi:10.1021/acsomega.0c00429
An investigation into the use of low quantities of functional additives to control drug release from hot melt extruded solid dispersions for poorly soluble drug delivery.
Alqahtani, F., Belton, P., Ward, A., Asare-Addo, K., & Qi, S. (2020). An investigation into the use of low quantities of functional additives to control drug release from hot melt extruded solid dispersions for poorly soluble drug delivery.. International journal of pharmaceutics, 579, 119172. doi:10.1016/j.ijpharm.2020.119172
Preparation and Characterization of an Electrospun PLA-Cyclodextrins Composite for Simultaneous High-Efficiency PM and VOC Removal
Palmieri, S., Pierpaoli, M., Riderelli, L., Qi, S., & Ruello, M. L. (2020). Preparation and Characterization of an Electrospun PLA-Cyclodextrins Composite for Simultaneous High-Efficiency PM and VOC Removal. Journal of Composites Science, 4(2), 79. doi:10.3390/jcs4020079
2019
Impact of Processing Parameters on the Quality of Pharmaceutical Solid Dosage Forms Produced by Fused Deposition Modeling (FDM).
Alhijjaj, M., Nasereddin, J., Belton, P., & Qi, S. (2019). Impact of Processing Parameters on the Quality of Pharmaceutical Solid Dosage Forms Produced by Fused Deposition Modeling (FDM).. Pharmaceutics, 11(12), E633. doi:10.3390/pharmaceutics11120633
Probing the molecular interactions between pharmaceutical polymeric carriers and bile salts in simulated gastrointestinal fluids using NMR spectroscopy.
Pigliacelli, C., Belton, P., Wilde, P., & Qi, S. (2019). Probing the molecular interactions between pharmaceutical polymeric carriers and bile salts in simulated gastrointestinal fluids using NMR spectroscopy.. Journal of colloid and interface science, 551, 147-154. doi:10.1016/j.jcis.2019.05.002
Reversing tumor stemness via orally targeted nanoparticles achieves efficient colon cancer treatment.
Xu, J., Zhang, Y., Xu, J., Wang, M., Liu, G., Wang, J., . . . Nie, G. (2019). Reversing tumor stemness via orally targeted nanoparticles achieves efficient colon cancer treatment.. Biomaterials, 216, 119247. doi:10.1016/j.biomaterials.2019.119247
Sulforaphane Mediates Glutathione Depletion via Polymeric Nanoparticles to Restore Cisplatin Chemosensitivity.
Xu, Y., Han, X., Li, Y., Min, H., Zhao, X., Zhang, Y., . . . Nie, G. (2019). Sulforaphane Mediates Glutathione Depletion via Polymeric Nanoparticles to Restore Cisplatin Chemosensitivity.. ACS nano, 13(11), 13445-13455. doi:10.1021/acsnano.9b07032
2018
Chapter 11: Personalized Polypills Produced by Fused Deposition Modeling 3D Printing
Qi, S., Nasereddin, J., & Alqahtani, F. (2018). Chapter 11: Personalized Polypills Produced by Fused Deposition Modeling 3D Printing. In M. Maniruzzaman (Ed.), 3D and 4D Printing in Biomedical Applications Process Engineering and Additive Manufacturing. John Wiley & Sons.
Novel Thermal Imaging Method for Rapid Screening of Drug-Polymer Miscibility for Solid Dispersion Based Formulation Development.
Alhijjaj, M., Belton, P., Fábián, L., Wellner, N., Reading, M., & Qi, S. (2018). Novel Thermal Imaging Method for Rapid Screening of Drug-Polymer Miscibility for Solid Dispersion Based Formulation Development.. Molecular pharmaceutics, 15(12), 5625-5636. doi:10.1021/acs.molpharmaceut.8b00798
Development of a Simple Mechanical Screening Method for Predicting the Feedability of a Pharmaceutical FDM 3D Printing Filament.
Nasereddin, J. M., Wellner, N., Alhijjaj, M., Belton, P., & Qi, S. (2018). Development of a Simple Mechanical Screening Method for Predicting the Feedability of a Pharmaceutical FDM 3D Printing Filament.. Pharmaceutical research, 35(8), 151. doi:10.1007/s11095-018-2432-3
Suppression of Tumor Energy Supply by Liposomal Nanoparticle-Mediated Inhibition of Aerobic Glycolysis.
Zhang, Y., Wei, J., Xu, J., Leong, W. S., Liu, G., Ji, T., . . . Li, S. (2018). Suppression of Tumor Energy Supply by Liposomal Nanoparticle-Mediated Inhibition of Aerobic Glycolysis.. ACS applied materials & interfaces, 10(3), 2347-2353. doi:10.1021/acsami.7b16685
Towards controlling the crystallisation behaviour of fenofibrate melt: triggers of crystallisation and polymorphic transformation.
Tipduangta, P., Takieddin, K., Fábián, L., Belton, P., & Qi, S. (2018). Towards controlling the crystallisation behaviour of fenofibrate melt: triggers of crystallisation and polymorphic transformation.. RSC advances, 8(24), 13513-13525. doi:10.1039/c8ra01182f
2017
A multi-technique characterization of the stability of surfactant containing solid dispersion based buccal patches prepared by hot melt injection moulding.
Alhijjaj, M., Belton, P., & Qi, S. (2017). A multi-technique characterization of the stability of surfactant containing solid dispersion based buccal patches prepared by hot melt injection moulding.. International journal of pharmaceutics, 528(1-2), 547-562. doi:10.1016/j.ijpharm.2017.06.048
Characterization of Heterogeneity and Spatial Distribution of Phases in Complex Solid Dispersions by Thermal Analysis by Structural Characterization and X-ray Micro Computed Tomography.
Alhijjaj, M., Yassin, S., Reading, M., Zeitler, J. A., Belton, P., & Qi, S. (2017). Characterization of Heterogeneity and Spatial Distribution of Phases in Complex Solid Dispersions by Thermal Analysis by Structural Characterization and X-ray Micro Computed Tomography.. Pharmaceutical research, 34(5), 971-989. doi:10.1007/s11095-016-1923-3
Rationalising polymer selection for supersaturated film forming systems produced by an aerosol spray for the transdermal delivery of methylphenidate.
Edwards, A., Qi, S., Liu, F., Brown, M. B., & McAuley, W. J. (2017). Rationalising polymer selection for supersaturated film forming systems produced by an aerosol spray for the transdermal delivery of methylphenidate.. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 114, 164-174. doi:10.1016/j.ejpb.2017.01.013
Local Thermal Analysis by Structural Characterization (TASC)
Reading, M., Qi, S., & Alhijjaj, M. (2017). Local Thermal Analysis by Structural Characterization (TASC). In J. Šesták, P. Hubík, & J. J. Mareš (Eds.), Thermal Physics and Thermal Analysis From Macro to Micro, Highlighting Thermodynamics, Kinetics and Nanomaterials. Springer.
2016
Hot melt extruded transdermal films based on amorphous solid dispersions in Eudragit RS PO: The inclusion of hydrophilic additives to develop moisture-activated release systems.
Albarahmieh, E., Qi, S., & Craig, D. Q. M. (2016). Hot melt extruded transdermal films based on amorphous solid dispersions in Eudragit RS PO: The inclusion of hydrophilic additives to develop moisture-activated release systems.. International journal of pharmaceutics, 514(1), 270-281. doi:10.1016/j.ijpharm.2016.06.137
An investigation into the use of polymer blends to improve the printability of and regulate drug release from pharmaceutical solid dispersions prepared via fused deposition modeling (FDM) 3D printing.
Alhijjaj, M., Belton, P., & Qi, S. (2016). An investigation into the use of polymer blends to improve the printability of and regulate drug release from pharmaceutical solid dispersions prepared via fused deposition modeling (FDM) 3D printing.. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 108, 111-125. doi:10.1016/j.ejpb.2016.08.016
Thermal Analysis of Pharmaceuticals
Qi, S. (2016). Thermal Analysis of Pharmaceuticals. In A. Müllertz, Y. Perrie, & T. Rades (Eds.), Analytical Techniques in the Pharmaceutical Sciences. Springer.
Improvement of the in vitro safety profile and cytoprotective efficacy of amifostine against chemotherapy by PEGylation strategy.
Yang, X., Ding, Y., Ji, T., Zhao, X., Wang, H., Zhao, X., . . . Nie, G. (2016). Improvement of the in vitro safety profile and cytoprotective efficacy of amifostine against chemotherapy by PEGylation strategy.. Biochemical pharmacology, 108, 11-21. doi:10.1016/j.bcp.2016.02.014
Recent developments in micro- and nanofabrication techniques for the preparation of amorphous pharmaceutical dosage forms.
Qi, S., & Craig, D. (2016). Recent developments in micro- and nanofabrication techniques for the preparation of amorphous pharmaceutical dosage forms.. Advanced drug delivery reviews, 100, 67-84. doi:10.1016/j.addr.2016.01.003
Disorders in Pharmaceutical Polymers
Dudognon, E., & Qi, S. (2016). Disorders in Pharmaceutical Polymers. In Unknown Book (pp. 201-240). Wiley. doi:10.1002/9783527652693.ch8
Processing‐Induced Disorder in Pharmaceutical Materials
Qi, S. (2016). Processing‐Induced Disorder in Pharmaceutical Materials. In Unknown Book (pp. 467-490). Wiley. doi:10.1002/9783527652693.ch15
Controlled Release from Zein Matrices: Interplay of Drug Hydrophobicity and pH.
Bouman, J., Belton, P., Venema, P., van der Linden, E., de Vries, R., & Qi, S. (2016). Controlled Release from Zein Matrices: Interplay of Drug Hydrophobicity and pH.. Pharmaceutical research, 33(3), 673-685. doi:10.1007/s11095-015-1818-8
A SPION-eicosane protective coating for water soluble capsules: Evidence for on-demand drug release triggered by magnetic hyperthermia.
Che Rose, L., Bear, J. C., McNaughter, P. D., Southern, P., Piggott, R. B., Parkin, I. P., . . . Mayes, A. G. (2016). A SPION-eicosane protective coating for water soluble capsules: Evidence for on-demand drug release triggered by magnetic hyperthermia.. Scientific reports, 6, 20271. doi:10.1038/srep20271
Electrospun Polymer Blend Nanofibers for Tunable Drug Delivery: The Role of Transformative Phase Separation on Controlling the Release Rate.
Tipduangta, P., Belton, P., Fábián, L., Wang, L. Y., Tang, H., Eddleston, M., & Qi, S. (2016). Electrospun Polymer Blend Nanofibers for Tunable Drug Delivery: The Role of Transformative Phase Separation on Controlling the Release Rate.. Molecular pharmaceutics, 13(1), 25-39. doi:10.1021/acs.molpharmaceut.5b00359
On-demand, magnetic hyperthermia-triggered drug delivery: optimisation for the GI tract.
Che Rose, L., Bear, J. C., Southern, P., McNaughter, P. D., Piggott, R. B., Parkin, I. P., . . . Mayes, A. G. (2016). On-demand, magnetic hyperthermia-triggered drug delivery: optimisation for the GI tract.. Journal of materials chemistry. B, 4(9), 1704-1711. doi:10.1039/c5tb02068a
2015
An investigation into the influence of drug-polymer interactions on the miscibility, processability and structure of polyvinylpyrrolidone-based hot melt extrusion formulations.
Chan, S. -Y., Qi, S., & Craig, D. Q. M. (2015). An investigation into the influence of drug-polymer interactions on the miscibility, processability and structure of polyvinylpyrrolidone-based hot melt extrusion formulations.. International journal of pharmaceutics, 496(1), 95-106. doi:10.1016/j.ijpharm.2015.09.063
Disc-shaped polyoxyethylene glycol glycerides gel nanoparticles as novel protein delivery vehicles.
Codoni, D., Cowan, J., Bradley, J., McAuley, W. J., O'Connell, M. A., & Qi, S. (2015). Disc-shaped polyoxyethylene glycol glycerides gel nanoparticles as novel protein delivery vehicles.. International journal of pharmaceutics, 496(2), 1015-1025. doi:10.1016/j.ijpharm.2015.10.067
Preparation and Characterization of Ultrarapidly Dissolving Orodispersible Films for Treating and Preventing Iodine Deficiency in the Pediatric Population.
Rustemkyzy, C., Belton, P., & Qi, S. (2015). Preparation and Characterization of Ultrarapidly Dissolving Orodispersible Films for Treating and Preventing Iodine Deficiency in the Pediatric Population.. Journal of agricultural and food chemistry, 63(44), 9831-9838. doi:10.1021/acs.jafc.5b03953
Creating Drug Solubilization Compartments via Phase Separation in Multicomponent Buccal Patches Prepared by Direct Hot Melt Extrusion-Injection Molding.
Alhijjaj, M., Bouman, J., Wellner, N., Belton, P., & Qi, S. (2015). Creating Drug Solubilization Compartments via Phase Separation in Multicomponent Buccal Patches Prepared by Direct Hot Melt Extrusion-Injection Molding.. Molecular pharmaceutics, 12(12), 4349-4362. doi:10.1021/acs.molpharmaceut.5b00532
A New Low Melting-Point Polymorph of Fenofibrate Prepared via Talc Induced Heterogeneous Nucleation
Tipduangta, P., Takieddin, K., Fábián, L., Belton, P., & Qi, S. (2015). A New Low Melting-Point Polymorph of Fenofibrate Prepared via Talc Induced Heterogeneous Nucleation. Crystal Growth & Design, 15(10), 5011-5020. doi:10.1021/acs.cgd.5b00956
Thermal Analysis by Structural Characterization as a Method for Assessing Heterogeneity in Complex Solid Pharmaceutical Dosage Forms.
Alhijjaj, M., Reading, M., Belton, P., & Qi, S. (2015). Thermal Analysis by Structural Characterization as a Method for Assessing Heterogeneity in Complex Solid Pharmaceutical Dosage Forms.. Analytical chemistry, 87(21), 10848-10855. doi:10.1021/acs.analchem.5b02192
The Development of Direct Extrusion-Injection Moulded Zein Matrices as Novel Oral Controlled Drug Delivery Systems.
Bouman, J., Belton, P., Venema, P., van der Linden, E., de Vries, R., & Qi, S. (2015). The Development of Direct Extrusion-Injection Moulded Zein Matrices as Novel Oral Controlled Drug Delivery Systems.. Pharmaceutical research, 32(8), 2775-2786. doi:10.1007/s11095-015-1663-9
Nanostructural analysis of water distribution in hydrated multicomponent gels using thermal analysis and NMR relaxometry.
Codoni, D., Belton, P., & Qi, S. (2015). Nanostructural analysis of water distribution in hydrated multicomponent gels using thermal analysis and NMR relaxometry.. Molecular pharmaceutics, 12(6), 2068-2079. doi:10.1021/mp5008508
Molecular indicators of surface and bulk instability of hot melt extruded amorphous solid dispersions.
Yang, Z., Nollenberger, K., Albers, J., Craig, D., & Qi, S. (2015). Molecular indicators of surface and bulk instability of hot melt extruded amorphous solid dispersions.. Pharmaceutical research, 32(4), 1210-1228. doi:10.1007/s11095-014-1527-8
Solid Dispersion – a Pragmatic Method to Improve the Bioavailability of Poorly Soluble Drugs
Ke, P., Qi, S., Sadowski, G., & Ouyang, D. (2015). Solid Dispersion – a Pragmatic Method to Improve the Bioavailability of Poorly Soluble Drugs. In Unknown Book (pp. 81-100). Wiley. doi:10.1002/9781118573983.ch5
The use of quasi-isothermal modulated temperature differential scanning calorimetry for the characterization of slow crystallization processes in lipid-based solid self-emulsifying systems.
Otun, S. O., Meehan, E., Qi, S., & Craig, D. Q. M. (2015). The use of quasi-isothermal modulated temperature differential scanning calorimetry for the characterization of slow crystallization processes in lipid-based solid self-emulsifying systems.. Pharmaceutical research, 32(4), 1316-1324. doi:10.1007/s11095-014-1535-8
2014
Molecular implications of drug-polymer solubility in understanding the destabilization of solid dispersions by milling.
Yang, Z., Nollenberger, K., Albers, J., & Qi, S. (2014). Molecular implications of drug-polymer solubility in understanding the destabilization of solid dispersions by milling.. Molecular pharmaceutics, 11(7), 2453-2465. doi:10.1021/mp500205c
Physical stabilization of low-molecular-weight amorphous drugs in the solid state: a material science approach.
Qi, S., McAuley, W. J., Yang, Z., & Tipduangta, P. (2014). Physical stabilization of low-molecular-weight amorphous drugs in the solid state: a material science approach.. Therapeutic delivery, 5(7), 817-841. doi:10.4155/tde.14.39
Spatial characterization of hot melt extruded dispersion systems using thermal atomic force microscopy methods: the effects of processing parameters on phase separation.
Moffat, J. G., Qi, S., & Craig, D. Q. M. (2014). Spatial characterization of hot melt extruded dispersion systems using thermal atomic force microscopy methods: the effects of processing parameters on phase separation.. Pharmaceutical research, 31(7), 1744-1752. doi:10.1007/s11095-013-1279-x
The effect of processing on the surface physical stability of amorphous solid dispersions.
Yang, Z., Nollenberger, K., Albers, J., Moffat, J., Craig, D., & Qi, S. (2014). The effect of processing on the surface physical stability of amorphous solid dispersions.. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 88(3), 897-908. doi:10.1016/j.ejpb.2014.07.013
2013
Stabilisation of amorphous drugs under high humidity using pharmaceutical thin films.
Ng, Y. C., Yang, Z., McAuley, W. J., & Qi, S. (2013). Stabilisation of amorphous drugs under high humidity using pharmaceutical thin films.. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 84(3), 555-565. doi:10.1016/j.ejpb.2013.01.008
Microstructure of an immiscible polymer blend and its stabilization effect on amorphous solid dispersions.
Yang, Z., Nollenberger, K., Albers, J., Craig, D., & Qi, S. (2013). Microstructure of an immiscible polymer blend and its stabilization effect on amorphous solid dispersions.. Molecular pharmaceutics, 10(7), 2767-2780. doi:10.1021/mp400209w
Moisture uptake of polyoxyethylene glycol glycerides used as matrices for drug delivery: kinetic modelling and practical implications.
Qi, S., Belton, P., McAuley, W., Codoni, D., & Darji, N. (2013). Moisture uptake of polyoxyethylene glycol glycerides used as matrices for drug delivery: kinetic modelling and practical implications.. Pharmaceutical research, 30(4), 1123-1136. doi:10.1007/s11095-012-0948-5
Early stage phase separation in pharmaceutical solid dispersion thin films under high humidity: improved spatial understanding using probe-based thermal and spectroscopic nanocharacterization methods.
Qi, S., Moffat, J. G., & Yang, Z. (2013). Early stage phase separation in pharmaceutical solid dispersion thin films under high humidity: improved spatial understanding using probe-based thermal and spectroscopic nanocharacterization methods.. Molecular pharmaceutics, 10(3), 918-930. doi:10.1021/mp300557q
Insights into the role of polymer-surfactant complexes in drug solubilisation/stabilisation during drug release from solid dispersions.
Qi, S., Roser, S., Edler, K. J., Pigliacelli, C., Rogerson, M., Weuts, I., . . . Stokbroekx, S. (2013). Insights into the role of polymer-surfactant complexes in drug solubilisation/stabilisation during drug release from solid dispersions.. Pharmaceutical research, 30(1), 290-302. doi:10.1007/s11095-012-0873-7
2012
The development of modulated, quasi-isothermal and ultraslow thermal methods as a means of characterizing the α to γ indomethacin polymorphic transformation.
Qi, S., & Craig, D. Q. M. (2012). The development of modulated, quasi-isothermal and ultraslow thermal methods as a means of characterizing the α to γ indomethacin polymorphic transformation.. Molecular pharmaceutics, 9(5), 1087-1099. doi:10.1021/mp2003412
2011
Compositional analysis of low quantities of phase separation in hot-melt-extruded solid dispersions: a combined atomic force microscopy, photothermal fourier-transform infrared microspectroscopy, and localised thermal analysis approach.
Qi, S., Belton, P., Nollenberger, K., Gryczke, A., & Craig, D. Q. M. (2011). Compositional analysis of low quantities of phase separation in hot-melt-extruded solid dispersions: a combined atomic force microscopy, photothermal fourier-transform infrared microspectroscopy, and localised thermal analysis approach.. Pharmaceutical research, 28(9), 2311-2326. doi:10.1007/s11095-011-0461-2
Physicochemical properties of the amorphous drug, cast films, and spray dried powders to predict formulation probability of success for solid dispersions: etravirine.
Weuts, I., Van Dycke, F., Voorspoels, J., De Cort, S., Stokbroekx, S., Leemans, R., . . . Reading, M. (2011). Physicochemical properties of the amorphous drug, cast films, and spray dried powders to predict formulation probability of success for solid dispersions: etravirine.. Journal of pharmaceutical sciences, 100(1), 260-274. doi:10.1002/jps.22242
2010
Detection of phase separation in hot melt extruded solid dispersion formulations: Global vs. localized characterization
Qi, S., & Craig, D. Q. M. (2010). Detection of phase separation in hot melt extruded solid dispersion formulations: Global vs. localized characterization. American Pharmaceutical Review, 13(6), 68-74.
Spray chilling of drugs with lipids: Considerations in the development of controlled and enhanced release lipid particles
Qi, S., & Craig, D. Q. M. (2010). Spray chilling of drugs with lipids: Considerations in the development of controlled and enhanced release lipid particles. American Pharmaceutical Review, 13(3), 81-84.
An investigation into the crystallisation behaviour of an amorphous cryomilled pharmaceutical material above and below the glass transition temperature.
Qi, S., Weuts, I., De Cort, S., Stokbroekx, S., Leemans, R., Reading, M., . . . Craig, D. Q. M. (2010). An investigation into the crystallisation behaviour of an amorphous cryomilled pharmaceutical material above and below the glass transition temperature.. Journal of pharmaceutical sciences, 99(1), 196-208. doi:10.1002/jps.21811
An investigation into the mechanism of dissolution rate enhancement of poorly water-soluble drugs from spray chilled gelucire 50/13 microspheres.
Qi, S., Marchaud, D., & Craig, D. Q. M. (2010). An investigation into the mechanism of dissolution rate enhancement of poorly water-soluble drugs from spray chilled gelucire 50/13 microspheres.. Journal of pharmaceutical sciences, 99(1), 262-274. doi:10.1002/jps.21832
Characterisation and prediction of phase separation in hot-melt extruded solid dispersions: a thermal, microscopic and NMR relaxometry study.
Qi, S., Belton, P., Nollenberger, K., Clayden, N., Reading, M., & Craig, D. Q. M. (2010). Characterisation and prediction of phase separation in hot-melt extruded solid dispersions: a thermal, microscopic and NMR relaxometry study.. Pharmaceutical research, 27(9), 1869-1883. doi:10.1007/s11095-010-0185-8
Solid lipid microparticles produced by spray congealing: influence of the atomizer on microparticle characteristics and mathematical modeling of the drug release.
Passerini, N., Qi, S., Albertini, B., Grassi, M., Rodriguez, L., & Craig, D. Q. M. (2010). Solid lipid microparticles produced by spray congealing: influence of the atomizer on microparticle characteristics and mathematical modeling of the drug release.. Journal of pharmaceutical sciences, 99(2), 916-931. doi:10.1002/jps.21854
2009
Paracetamol-loaded poly(epsilon-caprolactone) layered silicate nanocomposites prepared using hot-melt extrusion.
Campbell, K., Qi, S., Craig, D. Q. M., & McNally, T. (2009). Paracetamol-loaded poly(epsilon-caprolactone) layered silicate nanocomposites prepared using hot-melt extrusion.. Journal of pharmaceutical sciences, 98(12), 4831-4843. doi:10.1002/jps.21787
2008
An investigation into the effects of thermal history on the crystallisation behaviour of amorphous paracetamol.
Qi, S., Avalle, P., Saklatvala, R., & Craig, D. Q. M. (2008). An investigation into the effects of thermal history on the crystallisation behaviour of amorphous paracetamol.. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 69(1), 364-371. doi:10.1016/j.ejpb.2007.10.008
Characterisation of solid dispersions of paracetamol and EUDRAGIT E prepared by hot-melt extrusion using thermal, microthermal and spectroscopic analysis.
Qi, S., Gryczke, A., Belton, P., & Craig, D. Q. M. (2008). Characterisation of solid dispersions of paracetamol and EUDRAGIT E prepared by hot-melt extrusion using thermal, microthermal and spectroscopic analysis.. International journal of pharmaceutics, 354(1-2), 158-167. doi:10.1016/j.ijpharm.2007.11.048
The development of microthermal analysis and photothermal microspectroscopy as novel approaches to drug-excipient compatibility studies.
Harding, L., Qi, S., Hill, G., Reading, M., & Craig, D. Q. M. (2008). The development of microthermal analysis and photothermal microspectroscopy as novel approaches to drug-excipient compatibility studies.. International journal of pharmaceutics, 354(1-2), 149-157. doi:10.1016/j.ijpharm.2007.11.009
A laser imaging and neutron reflection investigation into the monolayer behaviour of fatty acids used for taste masking microspheres.
Qi, S., Roser, S. J., Deutsch, D., Barker, S. A., & Craig, D. Q. M. (2008). A laser imaging and neutron reflection investigation into the monolayer behaviour of fatty acids used for taste masking microspheres.. Journal of pharmaceutical sciences, 97(5), 1864-1877. doi:10.1002/jps.21100
An investigation into the mechanisms of drug release from taste-masking fatty acid microspheres.
Qi, S., Deutsch, D., & Craig, D. Q. M. (2008). An investigation into the mechanisms of drug release from taste-masking fatty acid microspheres.. Journal of pharmaceutical sciences, 97(9), 3842-3854. doi:10.1002/jps.21243
2006
An investigation into the interaction between taste masking fatty acid microspheres and alkaline buffer using thermal and spectroscopic analysis.
Qi, S., Deutsch, D., & Craig, D. Q. M. (2006). An investigation into the interaction between taste masking fatty acid microspheres and alkaline buffer using thermal and spectroscopic analysis.. Journal of pharmaceutical sciences, 95(5), 1022-1028. doi:10.1002/jps.20596
2004
Transport of leuprolide across rat intestine, rabbit intestine and Caco-2 cell monolayer.
Guo, J., Ping, Q., Jiang, G., Dong, J., Qi, S., Feng, L., . . . Li, C. (2004). Transport of leuprolide across rat intestine, rabbit intestine and Caco-2 cell monolayer.. International journal of pharmaceutics, 278(2), 415-422. doi:10.1016/j.ijpharm.2004.03.031