Research outputs
2025
NRF2 upregulation by CDDO-Me protects AC16 human cardiomyocytes against doxorubicin-induced toxicity.
Roberts, J. A., Batie, M., Ponsford, A. H., Poh, J., Hewitt, B. J., Botfield, H. F., . . . Sharma, P. (2025). NRF2 upregulation by CDDO-Me protects AC16 human cardiomyocytes against doxorubicin-induced toxicity.. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 194, 118878. doi:10.1016/j.biopha.2025.118878
NRF2 upregulation by CDDO-Me protects AC16 human cardiomyocytes against doxorubicin-induced toxicity
OTUD6B regulates KIFC1-dependent centrosome clustering and breast cancer cell survival.
Marotta, V. E., Sabat-Pośpiech, D., Fielding, A. B., Ponsford, A. H., Thomaz, A., Querques, F., . . . Coulson, J. M. (2025). OTUD6B regulates KIFC1-dependent centrosome clustering and breast cancer cell survival.. EMBO reports, 26(4), 1003-1035. doi:10.1038/s44319-024-00361-w
2021
Live imaging of intra-lysosome pH in cell lines and primary neuronal culture using a novel genetically encoded biosensor
Ponsford, A. H., Ryan, T. A., Raimondi, A., Cocucci, E., Wycislo, S. A., Fröhlich, F., . . . Stagi, M. (2020). Live imaging of intra-lysosome pH in cell lines and primary neuronal culture using a novel genetically encoded biosensor. Autophagy, 1-19. doi:10.1080/15548627.2020.1771858
2020
A functionally defined high-density NRF2 interactome reveals new conditional regulators of ARE transactivation
Poh, J., Ponsford, A. H., Boyd, J., Woodsmith, J., Stelzl, U., Wanker, E., . . . Sanderson, C. M. (2020). A functionally defined high-density NRF2 interactome reveals new conditional regulators of ARE transactivation. Redox Biology, 37. doi:10.1016/j.redox.2020.101686
2019
Mitochondrial respiratory chain deficiency inhibits lysosomal hydrolysis
Fernandez-Mosquera, L., Yambire, K. F., Renata, C., Pereyra, L., Pabis, K., Ponsford, A. H., . . . Raimundo, N. (2019). Mitochondrial respiratory chain deficiency inhibits lysosomal hydrolysis. Autophagy, 15(9), 1572-1591. doi:10.1080/15548627.2019.1586256
2016
Ubiquitin-Dependent Modification of Skeletal Muscle by the Parasitic Nematode, Trichinella spiralis
White, R. R., Ponsford, A. H., Weekes, M. P., Rodrigues, R., Ascher, D. B., Mol, M., . . . Artavanis-Tsakonas, K. (2016). Ubiquitin-Dependent Modification of Skeletal Muscle by the Parasitic Nematode, Trichinella spiralis. PLoS Pathogens, 12(11). doi:10.1371/journal.ppat.1005977
A Systematic Analysis of the Human Nrf2 Network
Ponsford, A. H. (2016, March 17). A Systematic Analysis of the Human Nrf2 Network.
2015
Dissecting molecular cross-talk between Nrf2 and NF-κB response pathways
Wardyn, J. D., Ponsford, A. H., & Sanderson, C. M. (2015). Dissecting molecular cross-talk between Nrf2 and NF-κB response pathways. BIOCHEMICAL SOCIETY TRANSACTIONS, 43, 621-626. doi:10.1042/BST20150014