Taming Plastids for Biotechnology and Synthetic Biology

1:00pm - 2:00pm / Monday 27th January 2020 / Venue: LT1, Life Sciences Building Life Sciences Building
Type: Seminar / Category: Research / Series: GSTT Seminar Series
  • Suitable for: Those with an interest in Genomes, Systems and Therapeutic Targeting
  • Admission: Free
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Speaker: Ralph Bock

The plastid (chloroplast) genome represents an attractive target of genetic engineering in crop plants. Plastid transgenes often give very high expression levels, can be conveniently stacked in synthetic operons, and are largely excluded from pollen transmission, thus providing increased biosafety of transgenic crops. Recent research has greatly expanded our toolbox for plastid genome engineering and many new proof-of-principle applications have highlighted the enormous potential of the transplastomic technology in crop improvement and for the development of plants as bioreactors for the sustainable and cost-effective production of biopharmaceuticals, enzymes and raw materials for the chemical industry. In his talk, Ralph will describe recent technological advances with plastid transformation in seed plants and summarize progress with harnessing the potential of plastid genetic engineering in plant biotechnology and synthetic biology. Selected applications in three areas will be discussed: metabolic pathway engineering, resistance engineering and molecular farming for new pharmaceuticals.