What can the Endometrium Teach us About Wound Repair?

1:00pm - 2:00pm / Monday 2nd December 2019 / Venue: Lecture Theatre 1 Life Sciences Building
Type: Seminar / Category: Research / Series: GSTT Seminar Series
  • Suitable for: Staff and students with an interest in Genomes, Systems and Therapeutic Targeting
  • Admission: Free
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Speaker: Philippa Saunders (University of Edinburgh)

Efficient wound healing after injury is essential for restoration of normal tissue function and deficits in repair processes are detrimental to health. The endometrium is a complex, multicellular, hormone-dependent tissue located within the uterus (womb) which is remarkable for its ability to experience regular, repeated episodes of scarless healing.

Philippa’s group have developed a mouse model of endometrial repair which has provided us with novel insights into role(s) of immune cells, cell-cell interactions and tissue progenitors in scar-free healing. Their findings have implications for treatment of women’s health disorders including heavy menstrual bleeding, infertility and endometriosis as well as aberrant repair of non-reproductive tissues.