Prof Jamie McPhee, Manchester Mewtropolitan University. 'Human Neuromuscular Function in Old Age: An in vivo approach to the study of sarcopenia.’ Host: Kasia Whysall

12:00pm - 1:00pm / Tuesday 29th October 2019 / Venue: William Henry Duncan Apex Building
Type: Seminar / Category: Research / Series: Institute of Ageing & Chronic Disease seminar series
  • 0151 794 9003
  • Suitable for: Staff and students
  • Admission: Free to staff and students
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Jamie was trained in human muscle and exercise physiology and completed a postdoctoral position as Workpackage Leader in the pan-European “MyoAge” study designed to understand and combat old age muscle wasting and weakness (EUFP7). He was appointed as Lecturer in Human Physiology at Manchester Metropolitan University in 2012 and is now Full Professor and Head of Department of Sports and Exercise Sciences. He is also Deputy Director of a Doctoral Training Alliance in Applied Bioscience for Health that currently includes 92 PhD students.
Jamie’s research aims to understand basic mechanisms of human muscle ageing and to trial interventions, including nutrition and physical activity, to maintain or improve muscle function in old age. In his talk, Jamie will discuss recent work to estimate the contributions of muscle loss, reduced voluntary activation (motor unit recruitment) and in situ specific force (muscle ‘quality’) to weakness in old age. He will also discuss the role of muscle fibre atrophy, fibre loss and declining numbers of motor neurons (motor units) as causes of low muscle mass and physical function, commonly known as sarcopenia1,2.
The research has been funded by the European Commission (FP7 and H2020), Nutricia Research, charities, and the UK Medical Research Council. The doctoral training alliance recently received funding from the European Commission through Marie Sklodowska-Curie COFUND to recruit another 82 Early Career Researchers (PhD students) between 2019 – 2022.
Background reading: 1. McPhee et al. J Gerontol Series A. Feb 2018. In press. PMID:29529132; 2. Piasecki et al. J Physiol. 2018 May 1;596(9):1627-1637. PMID:29527694