Dr Joanna Bridger, Reader in Chromosome Biology and Head of Genome Engineering & Maintenance Network (GEMN).

12:00pm - 1:00pm / Wednesday 1st May 2019 / Venue: William Henry Duncan Apex Building
Type: Seminar / Category: Research / Series: Institute of Ageing & Chronic Disease seminar series
  • 0151 794 9003
  • Suitable for: Staff and students.
  • Admission: Free to staff and students.
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"Of snails and men" - chromatin movement in aged nuclei.
Jo leads the Laboratory of Nuclear and Genomic Health, Division of BioSciences at Brunel University London. She is a Fellow of the Royal Society of Biology and an Ambassador for the British Society of Cell Biology. Her research is concerned with how the genome is spatially organised, influenced and manipulated within its environment, the cell nucleus. The cell nucleus is a highly organised organelle, with chromosomes in non-random positions, anchored by nuclear structures. Her group has had a number of major advances in the field, including >50 research papers and >4000 citations. She is currently focused on aspects of genome behaviour in diverse areas ranging from replicative senescence, the premature ageing disease Hutchinson-Gilford Progeria Syndrome (HGPS), the host::pathogen interactions and female cancers. Her research aims to understand how structures such as the nuclear lamina, nucleoskeleton and nuclear motors influence the functionality of the genome. In cancer and premature ageing diseases like progeria chromosomes are mis-located and her group is using drugs that can restore positioning in these diseases. In response to a stimulus, genes and chromosomes move to new locations. Her research is investigating this rapid movement that they call "chromobility" and have gained evidence that this is elicited through nuclear motors.

Host: Vanja Pekovic-Vaughan. All IACD students are expected to attend.
Contact: leifh@liverpool.ac.uk and Louise.Simpson@liverpool.ac.uk
if you would like seminar broadcast live to Leahurst or Aintree
Early lunch 11.15 am - all welcome. Please always sign attendance sheet.