Michele Madigan

Dr Michele Madigan, University of New South Wales. 'Emerging from the Darkness: Spotlight on Human Choroidal Melanocytes and Naevi.'

1:00pm - 2:00pm / Wednesday 20th March 2019 / Venue: William Henry Duncan Apex Building
Type: Seminar / Category: Research
  • 0151 794 9003
  • Suitable for: Staff and students
  • Admission: Free to staff and students
Add this event to my calendar

Create a calendar file

Click on "Create a calendar file" and your browser will download a .ics file for this event.

Microsoft Outlook: Download the file, double-click it to open it in Outlook, then click on "Save & Close" to save it to your calendar. If that doesn't work go into Outlook, click on the File tab, then on Open & Export, then Open Calendar. Select your .ics file then click on "Save & Close".

Google Calendar: download the file, then go into your calendar. On the left where it says "Other calendars" click on the arrow icon and then click on Import calendar. Click on Browse and select the .ics file, then click on Import.

Apple Calendar: The file may open automatically with an option to save it to your calendar. If not, download the file, then you can either drag it to Calendar or import the file by going to File >Import > Import and choosing the .ics file.

The choroid, ciliary body and iris (uvea) of the eye form a richly pigmented vascular tract between the neural retina and outer sclera, essential for outer retinal function and homeostasis. The pigmented, melanin-producing melanocytes are cranial neural-crest derived and populate a mesodermal microenvironment with distinct extracellular and cellular interactions, compared to the better-known skin melanocytes. The heterogeneously pigmented melanocytes (and melanins) are important fornormal eye physiology including photoprotection, and regulation of oxidative damage and immunological responses. They also display a unique cell biology and gene profile, as do primary uveal naevi (and melanomas). This seminar will highlight current research on human choroidal melanocytes, melanins and choroidal naevi.