'Towards understanding hydrogen peroxide in redox biology.'
Institute for Biochemistry and Molecular Biology I, and Leibniz Research Institute for Environmental Medicine, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany
Hydrogen peroxide emerged as a central redox signaling molecule. Generation, transport and capture of H2O2 in biological settings as well as their biological consequences can now be addressed. Basal physiological intracellular concentration of hydrogen peroxide is at around 10 nanomolar, a condition denoted as oxidative eustress.
Helmut Sies, MD, PhD(hon), MD(hon), FRCP, is a Research Professor at Heinrich Heine University Düsseldorf Medical School. He studied medicine at the Universities of Tübingen, Paris and Munich, and he was Full Professor and Chairman of the Institute of Biochemistry and Molecular Biology I at Düsseldorf (1979-2007).
His research interests: Oxidative stress, hydrogen peroxide, glutathione, oxidants and antioxidants, nutritional biochemistry (selenoproteins, carotenoids, polyphenols).