DNA-protein crosslink proteolysis repair in genome stability, ageing and cancer
1:00pm - 2:00pm /
Friday 10th March 2017
/ Venue: Cancer Research Centre
Type: Seminar /
Category: Department
/ Series: North West Cancer Research Centre – University of Liverpool Seminar Series
- Dawn Kohler
- Admission: Free
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Kristijan Ramadan is an Associate Professor at the CRUK/MRC Oxford Institute for Radiation Oncology. He holds degrees in Veterinary Medicine (DVM) and Pathology (MSc), and a PhD in Biochemistry and Molecular Biology from the University of Zurich. Between 2009 and 2013 he was a Junior Group Leader and Lecturer at the Institute of Pharmacology and Toxicology-Vetsuisse, University of Zurich.
Prof Ramadan’s laboratory is focused on characterising chromatin-associated degradation pathways (CHROMAD) that help maintain genome stability. He has identified a central component of the ubiquitin proteasome pathway, p97 (also known as VCP or Cdc48) that plays an essential role in this process by degrading chromatin-associated proteins during various metabolic processes. He also recently discovered a novel pathway called DNAprotein crosslink proteolysis repair, which is essential in the protection from genome instability, premature ageing and cancer.
More information about Prof Ramadan’s work can be found at: https://www.oncology.ox.ac.uk/research/kristijan-ramadan
If you would like to meet Prof Kristijan Ramadan on the day, please contact Dr Jason Parsons: j.parsons@liverpool.ac.uk
Prof Ramadan’s laboratory is focused on characterising chromatin-associated degradation pathways (CHROMAD) that help maintain genome stability. He has identified a central component of the ubiquitin proteasome pathway, p97 (also known as VCP or Cdc48) that plays an essential role in this process by degrading chromatin-associated proteins during various metabolic processes. He also recently discovered a novel pathway called DNAprotein crosslink proteolysis repair, which is essential in the protection from genome instability, premature ageing and cancer.
More information about Prof Ramadan’s work can be found at: https://www.oncology.ox.ac.uk/research/kristijan-ramadan
If you would like to meet Prof Kristijan Ramadan on the day, please contact Dr Jason Parsons: j.parsons@liverpool.ac.uk