GSTT SEMINAR: Roy Goodacre, University of Manchester - Title: 'Metabolomics for investigating human health and disease'
12:00pm - 1:00pm /
Monday 19th October 2015
Type: Seminar /
Category: Department
- Prof Rob Beynon
- Admission: Free
- Book now
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Metabolomics is a growing discipline that allows the analysis of the thousands of structural different small molecules found within a biological system. These metabolites can be measured using a variety of different analytical approaches including NMR spectroscopy or alternatively can be separated and quantified using gas or liquid chromatography coupled to mass spectrometry, after which the hope is that specific biomarkers can be discovered and linked to health, nutrition and disease.
This presentation will provide an overview of metabolomics and will give a flavour of how data are generated and analysed. The role of metabolomics in nutrigenomics will also be discussed, as well as the concepts of the human being considered a superorganism and all the complexities this generates that need to be overcome to understand human health and disease.
During the presentation, I will also discuss the bioanalytical pathway that we have developed as part of our human serum metabolome project (http://www.husermet.org/) that is need in order to negotiate the metabolite superhighway such that rigorously identified metabolites are discovered that can be used for understanding normal population behaviours and for disease stratification.
This presentation will provide an overview of metabolomics and will give a flavour of how data are generated and analysed. The role of metabolomics in nutrigenomics will also be discussed, as well as the concepts of the human being considered a superorganism and all the complexities this generates that need to be overcome to understand human health and disease.
During the presentation, I will also discuss the bioanalytical pathway that we have developed as part of our human serum metabolome project (http://www.husermet.org/) that is need in order to negotiate the metabolite superhighway such that rigorously identified metabolites are discovered that can be used for understanding normal population behaviours and for disease stratification.