Dr Mike Davies BSc PhD

Molecular & Clinical Cancer Medicine

+44 (0)151 794 9105
Work email Michael.Davies@liverpool.ac.uk

Publications

Selected Publications

Circulating Proteome for Pulmonary Nodule Malignancy. (Journal article - 2023)
Lung cancer mortality reduction by LDCT screening: UKLS randomised trial results and international meta-analysis (Journal article - 2021)
Liverpool Lung Project lung cancer risk stratification model: calibration and prospective validation (Journal article - 2021)
Plasma protein biomarkers for early prediction of lung cancer (Journal article - 2023)
Unique volatolomic signatures of TP53 and KRAS in lung cells (Journal article - 2014)
A microRNA-based prediction algorithm for diagnosis of non-small lung cell carcinoma in minimal biopsy material (Journal article - 2013)
Heterogeneity of PD-L1 expression in non-small cell lung cancer: Implications for specimen sampling in predicting treatment response (Journal article - 2019)
Expression and splicing of the unfolded protein response gene XBP-1 are sieniticantly associated with clinical outcome of endocrine-treated breast cancer (Journal article - 2008)
Association of oestrogen receptor beta 2 (ERβ2/ERβcx) with outcome of adjuvant endocrine treatment for primary breast cancer -: a retrospective study (Journal article - 2007)
Expression of the calcium-binding protein S100A4 (p9Ka) in MMTV-neu transgenic mice induces metastasis of mammary tumours (Journal article - 1996)

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2024

Lung cancer in ever- and never-smokers: findings from multi-population GWAS studies. (Journal article)

Li, Y., Xiao, X., Li, J., Han, Y., Cheng, C., Fernandes, G. F., . . . Amos, C. I. (2024). Lung cancer in ever- and never-smokers: findings from multi-population GWAS studies.. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. doi:10.1158/1055-9965.epi-23-0613

DOI: 10.1158/1055-9965.epi-23-0613

2023

Identification of genetically predicted DNA methylation markers associated with non-small cell lung cancer risk among 34,964 cases and 448,579 controls. (Journal article)

Zhao, X., Yang, M., Fan, J., Wang, M., Wang, Y., Qin, N., . . . Dai, J. (2023). Identification of genetically predicted DNA methylation markers associated with non-small cell lung cancer risk among 34,964 cases and 448,579 controls.. Cancer. doi:10.1002/cncr.35130

DOI: 10.1002/cncr.35130

Large-scale whole exome sequencing studies identify two genes,CTSL and APOE, associated with lung cancer. (Journal article)

Xu, J., Xu, W., Choi, J., Brhane, Y., Christiani, D. C., Kothari, J., . . . Briollais, L. (2023). Large-scale whole exome sequencing studies identify two genes,CTSL and APOE, associated with lung cancer.. PLoS genetics, 19(9), e1010902. doi:10.1371/journal.pgen.1010902

DOI: 10.1371/journal.pgen.1010902

Association between duration of smoking abstinence before non-small-cell lung cancer diagnosis and survival: a retrospective, pooled analysis of cohort studies (Journal article)

Fares, A. F., Li, Y., Jiang, M., Brown, M. C., Lam, A. C. L., Aggarwal, R., . . . Liu, G. (2023). Association between duration of smoking abstinence before non-small-cell lung cancer diagnosis and survival: a retrospective, pooled analysis of cohort studies. LANCET PUBLIC HEALTH, 8(9), E691-E700. Retrieved from https://www.webofscience.com/

Non-coding RNA-directed therapeutics in lung cancer: Delivery technologies and clinical applications (Journal article)

Abdellatif, A. A. H., Scagnetti, G., Younis, M. A., Bouazzaoui, A., Tawfeek, H. M., Aldosari, B. N., . . . Saleem, I. (2023). Non-coding RNA-directed therapeutics in lung cancer: Delivery technologies and clinical applications. COLLOIDS AND SURFACES B-BIOINTERFACES, 229. doi:10.1016/j.colsurfb.2023.113466

DOI: 10.1016/j.colsurfb.2023.113466

Candidate pathway analysis of surfactant proteins identifies CTSH and SFTA2 that influences lung cancer risk. (Journal article)

Luyapan, J., Bossé, Y., Li, Z., Xiao, X., Rosenberger, A., Hung, R. J., . . . Amos, C. I. (2023). Candidate pathway analysis of surfactant proteins identifies CTSH and SFTA2 that influences lung cancer risk.. Human molecular genetics, ddad095. doi:10.1093/hmg/ddad095

DOI: 10.1093/hmg/ddad095

Plasma protein biomarkers for early prediction of lung cancer (Journal article)

Davies, M. P. A., Sato, T., Ashoor, H., Hou, L., Liloglou, T., Yang, R., & Field, J. K. (2023). Plasma protein biomarkers for early prediction of lung cancer. EBIOMEDICINE, 93. doi:10.1016/j.ebiom.2023.104686

DOI: 10.1016/j.ebiom.2023.104686

Circulating Proteome for Pulmonary Nodule Malignancy. (Journal article)

Khodayari Moez, E., Warkentin, M. T., Brhane, Y., Lam, S., Field, J. K., Liu, G., . . . Hung, R. J. (2023). Circulating Proteome for Pulmonary Nodule Malignancy.. Journal of the National Cancer Institute, djad122. doi:10.1093/jnci/djad122

DOI: 10.1093/jnci/djad122

Mosaic chromosomal alterations is associated with increased lung cancer risk: insight from the INTEGRAL-ILCCO cohort analysis. (Journal article)

Cheng, C., Hong, W., Li, Y., Xiao, X., McKay, J., Han, Y., . . . INTEGRAL-ILCCO lung cancer consortium. (2023). Mosaic chromosomal alterations is associated with increased lung cancer risk: insight from the INTEGRAL-ILCCO cohort analysis.. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, S1556-0864(23)00527-0. doi:10.1016/j.jtho.2023.05.001

DOI: 10.1016/j.jtho.2023.05.001

Design and methodological considerations for biomarker discovery and validation in the Integrative Analysis of Lung Cancer Etiology and Risk (INTEGRAL) Program (Journal article)

Robbins, H. A., Alcala, K., Moez, E. K., Guida, F., Thomas, S., Zahed, H., . . . Hung, R. J. (2023). Design and methodological considerations for biomarker discovery and validation in the Integrative Analysis of Lung Cancer Etiology and Risk (INTEGRAL) Program. ANNALS OF EPIDEMIOLOGY, 77, 1-12. doi:10.1016/j.annepidem.2022.10.014

DOI: 10.1016/j.annepidem.2022.10.014

On the Non-Linearity of Radon-Induced Lung Cancer (Preprint)

DOI: 10.2139/ssrn.4347965

2022

EP01.06-006 Impact of Low Dose CT Screening on Cause of Death in Different Socio-Economic Groups (Journal article)

Davies, M. P. A., Vulkan, D., Gabe, R., Duffy, S. W., & Field, J. K. (2022). EP01.06-006 Impact of Low Dose CT Screening on Cause of Death in Different Socio-Economic Groups. Journal of Thoracic Oncology, 17(9), S190. doi:10.1016/j.jtho.2022.07.318

DOI: 10.1016/j.jtho.2022.07.318

Genome-wide interaction analysis identified low-frequency variants with sex disparity in lung cancer risk (Journal article)

Li, Y., Xiao, X., Li, J., Byun, J., Cheng, C., Bosse, Y., . . . Amos, C. I. (2022). Genome-wide interaction analysis identified low-frequency variants with sex disparity in lung cancer risk. HUMAN MOLECULAR GENETICS, 31(16), 2831-2843. doi:10.1093/hmg/ddac030

DOI: 10.1093/hmg/ddac030

On the non-linearity of radon-induced lung cancer (Preprint)

DOI: 10.21203/rs.3.rs-1933741/v1

Design and methodological considerations for biomarker discovery and validation in the Integrative Analysis of Lung Cancer Etiology and Risk (INTEGRAL) Program (Preprint)

DOI: 10.1101/2022.03.21.22272544

Impact of risk-based low dose CT screening on different socio-economic groups (Journal article)

Davies, M., Vulkan, D., Gabe, R., Duffy, S., & Field, J. (2022). Impact of risk-based low dose CT screening on different socio-economic groups. Lung Cancer, 165, S20. doi:10.1016/s0169-5002(22)00088-5

DOI: 10.1016/s0169-5002(22)00088-5

Gene-gene interaction of AhRwith and within the Wntcascade affects susceptibility to lung cancer (Journal article)

Rosenberger, A., Muttray, N., Hung, R. J., Christiani, D. C., Caporaso, N. E., Liu, G., . . . Bickeboeller, H. (2022). Gene-gene interaction of AhRwith and within the Wntcascade affects susceptibility to lung cancer. EUROPEAN JOURNAL OF MEDICAL RESEARCH, 27(1). doi:10.1186/s40001-022-00638-7

DOI: 10.1186/s40001-022-00638-7

Iam hiQ-a novel pair of accuracy indices for imputed genotypes (Journal article)

Rosenberger, A., Tozzi, V., Bickeboeller, H., & Consortium, I. N. T. E. G. R. A. L. -I. L. C. C. O. (2022). Iam hiQ-a novel pair of accuracy indices for imputed genotypes. BMC BIOINFORMATICS, 23(1). doi:10.1186/s12859-022-04568-3

DOI: 10.1186/s12859-022-04568-3

Accounting for EGFR mutations in epidemiological analyses of non-small cell lung cancers: Examples based on the International Lung Cancer Consortium data. (Journal article)

Schmid, S., Jiang, M., Brown, M. C., Fares, A., Garcia, M., Soriano, J., . . . Liu, G. (2022). Accounting for EGFR mutations in epidemiological analyses of non-small cell lung cancers: Examples based on the International Lung Cancer Consortium data.. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. doi:10.1158/1055-9965.epi-21-0747

DOI: 10.1158/1055-9965.epi-21-0747

Impact of Low Dose CT Screening on Cause of Death in Different Socio-Economic Groups (Conference Paper)

Davies, M. P. A., Vulkan, D., Gabe, R., Duffy, S. W., & Field, J. K. (2022). Impact of Low Dose CT Screening on Cause of Death in Different Socio-Economic Groups. In JOURNAL OF THORACIC ONCOLOGY Vol. 17 (pp. S190). Retrieved from https://www.webofscience.com/

2021

Lung cancer mortality reduction by LDCT screening: UKLS randomised trial results and international meta-analysis (Journal article)

Field, J. K., Vulkan, D., Davies, M. P. A., Baldwin, D. R., Brain, K. E., Devaraj, A., . . . Duffy, S. W. (2021). Lung cancer mortality reduction by LDCT screening: UKLS randomised trial results and international meta-analysis. LANCET REGIONAL HEALTH-EUROPE, 10. doi:10.1016/j.lanepe.2021.100179

DOI: 10.1016/j.lanepe.2021.100179

OA19.02 The UKLS Trial Outcome Results: Lung Cancer Mortality Reduction by LDCT Screening Confirmed in an International Meta-Analysis (Journal article)

Field, J., Vulkan, D., Davies, M., Gabe, R., & Duffy, S. (2021). OA19.02 The UKLS Trial Outcome Results: Lung Cancer Mortality Reduction by LDCT Screening Confirmed in an International Meta-Analysis. Journal of Thoracic Oncology, 16(10), S882. doi:10.1016/j.jtho.2021.08.098

DOI: 10.1016/j.jtho.2021.08.098

Gene-gene Interaction of AhR with and within the Wnt Cascade Affects Susceptibility to Lung Cancer (Preprint)

DOI: 10.21203/rs.3.rs-658360/v2

Genome-wide interaction analysis identified low-frequency variants with sex disparity in lung cancer risk (Preprint)

DOI: 10.21203/rs.3.rs-647012/v1

Gene-gene Interaction of AhR With and Within the Wnt Cascade Affects Susceptibility to Lung Cancer (Preprint)

DOI: 10.21203/rs.3.rs-658360/v1

Lung cancer risk in painters: results from the SYNERGY pooled case-control study consortium (Journal article)

Guha, N., Bouaoun, L., Kromhout, H., Vermeulen, R., Bruening, T., Behrens, T., . . . Olsson, A. (2021). Lung cancer risk in painters: results from the SYNERGY pooled case-control study consortium. OCCUPATIONAL AND ENVIRONMENTAL MEDICINE, 78(4), 269-278. doi:10.1136/oemed-2020-106770

DOI: 10.1136/oemed-2020-106770

FP07.02 Deep Learning Based Analysis of Multiplex IHC Accurately Interprets PD-L1 and Provides Prognostic Information in NSCLC (Journal article)

Haragan, A., Nekolla, K., Kapil, A., Brieu, N., Widmaier, M., Budco, A., . . . Gosney, J. (2021). FP07.02 Deep Learning Based Analysis of Multiplex IHC Accurately Interprets PD-L1 and Provides Prognostic Information in NSCLC. Journal of Thoracic Oncology, 16(3), S203. doi:10.1016/j.jtho.2021.01.102

DOI: 10.1016/j.jtho.2021.01.102

FP09.02 Calibration of the LLP Lung Cancer Risk Stratification Model: Prospective Validation in the UKLS Cohort of 76,000 People (Journal article)

Field, J., Vulkan, D., Davies, M., Duffy, S., & Gabe, R. (2021). FP09.02 Calibration of the LLP Lung Cancer Risk Stratification Model: Prospective Validation in the UKLS Cohort of 76,000 People. Journal of Thoracic Oncology, 16(3), S212. doi:10.1016/j.jtho.2021.01.119

DOI: 10.1016/j.jtho.2021.01.119

Rare deleterious germline variants and risk of lung cancer (Journal article)

Liu, Y., Xia, J., McKay, J., Tsavachidis, S., Xiao, X., Spitz, M. R., . . . Amos, C. I. (2021). Rare deleterious germline variants and risk of lung cancer. NPJ PRECISION ONCOLOGY, 5(1). doi:10.1038/s41698-021-00146-7

DOI: 10.1038/s41698-021-00146-7

Liverpool Lung Project lung cancer risk stratification model: calibration and prospective validation (Journal article)

Field, J. K., Vulkan, D., Davies, M. P. A., Duffy, S. W., & Gabe, R. (2021). Liverpool Lung Project lung cancer risk stratification model: calibration and prospective validation. THORAX, 76(2), 161-168. doi:10.1136/thoraxjnl-2020-215158

DOI: 10.1136/thoraxjnl-2020-215158

The relationship between body-mass index and overall survival in non-small cell lung cancer by sex, smoking status, and race: A pooled analysis of 20,937 International lung Cancer consortium (ILCCO) patients (Journal article)

Jiang, M., Fares, A. F., Shepshelovich, D., Yang, P., Christiani, D., Zhang, J., . . . Liu, G. (2021). The relationship between body-mass index and overall survival in non-small cell lung cancer by sex, smoking status, and race: A pooled analysis of 20,937 International lung Cancer consortium (ILCCO) patients. Lung Cancer, 152, 58-65. doi:10.1016/j.lungcan.2020.11.029

DOI: 10.1016/j.lungcan.2020.11.029

2020

Protein-altering germline mutations implicate novel genes related to lung cancer development (Journal article)

Ji, X., Mukherjee, S., Landi, M. T., Bosse, Y., Joubert, P., Zhu, D., . . . Amos, C. I. (2020). Protein-altering germline mutations implicate novel genes related to lung cancer development. NATURE COMMUNICATIONS, 11. doi:10.1038/s41467-020-15905-6

DOI: 10.1038/s41467-020-15905-6

Long non-coding RNA dysregulation is a frequent event in non-small cell lung carcinoma pathogenesis (Journal article)

Acha-Sagredo, A., Uko, B., Pantazi, P., Bediaga, N., Moschandrea, C., Rainbow, L., . . . Liloglou, T. (2020). Long non-coding RNA dysregulation is a frequent event in non-small cell lung carcinoma pathogenesis. British Journal of Cancer, 122(7), 1050-1058. doi:10.1038/s41416-020-0742-9

DOI: 10.1038/s41416-020-0742-9

Immune-mediated genetic pathways resulting in pulmonary function impairment increase lung cancer susceptibility (Journal article)

Kachuri, L., Johansson, M., Rashkin, S. R., Graff, R. E., Bosse, Y., Manem, V., . . . Hung, R. J. (2020). Immune-mediated genetic pathways resulting in pulmonary function impairment increase lung cancer susceptibility. NATURE COMMUNICATIONS, 11(1). doi:10.1038/s41467-019-13855-2

DOI: 10.1038/s41467-019-13855-2

2019

Potential genetic modifiers for somatic EGFR mutation in lung cancer: a meta-analysis and literature review (Journal article)

Cheng, Y. I., Gan, Y. C., Liu, D., Davies, M. P. A., Li, W. M., & Field, J. K. (2019). Potential genetic modifiers for somatic EGFR mutation in lung cancer: a meta-analysis and literature review. BMC CANCER, 19(1). doi:10.1186/s12885-019-6317-6

DOI: 10.1186/s12885-019-6317-6

The Role of Autophagy in Lung Disease (Chapter)

Davies, M. P. A., & Wilson, C. M. (2016). The Role of Autophagy in Lung Disease. In AUTOPHAGY IN CURRENT TRENDS IN CELLULAR PHYSIOLOGY AND PATHOLOGY (pp. 267-285). doi:10.5772/64167

DOI: 10.5772/64167

Implementation Planning of Lung Cancer Screening in China (Conference Paper)

Cheng, Y., Davies, M., Liu, D., Li, W., & Field, J. (2019). Implementation Planning of Lung Cancer Screening in China. In JOURNAL OF THORACIC ONCOLOGY Vol. 14 (pp. S1008). doi:10.1016/j.jtho.2019.08.2223

DOI: 10.1016/j.jtho.2019.08.2223

Pathogenic Germline Rare Variants and Risk of Lung Cancer (Conference Paper)

Liu, Y., Mckay, J., Xiao, X., Field, J., Davies, M., Brennan, P., . . . Amos, C. (2019). Pathogenic Germline Rare Variants and Risk of Lung Cancer. In JOURNAL OF THORACIC ONCOLOGY Vol. 14 (pp. S689-S690). doi:10.1016/j.jtho.2019.08.1465

DOI: 10.1016/j.jtho.2019.08.1465

Body Mass Index (BMI), BMI Change, and Overall Survival in Patients With SCLC and NSCLC: A Pooled Analysis of the International Lung Cancer Consortium (Journal article)

Shepshelovich, D., Xu, W., Lu, L., Fares, A., Yang, P., Christiani, D., . . . Hung, R. J. (2019). Body Mass Index (BMI), BMI Change, and Overall Survival in Patients With SCLC and NSCLC: A Pooled Analysis of the International Lung Cancer Consortium. JOURNAL OF THORACIC ONCOLOGY, 14(9), 1594-1607. doi:10.1016/j.jtho.2019.05.031

DOI: 10.1016/j.jtho.2019.05.031

Heterogeneity of PD-L1 expression in non-small cell lung cancer: Implications for specimen sampling in predicting treatment response (Journal article)

Haragan, A., Field, J. K., Davies, M. P. A., Escriu, C., Gruver, A., & Gosney, J. R. (2019). Heterogeneity of PD-L1 expression in non-small cell lung cancer: Implications for specimen sampling in predicting treatment response. Lung Cancer, 134, 79-84. doi:10.1016/j.lungcan.2019.06.005

DOI: 10.1016/j.lungcan.2019.06.005

Lung Cancer Risk in Never-Smokers of European Descent is Associated With Genetic Variation in the 5p15.33 TERT-CLPTM1Ll Region (Journal article)

Hung, R. J., Spitz, M. R., Houlston, R. S., Schwartz, A. G., Field, J. K., Ying, J., . . . Gorlova, O. Y. (2019). Lung Cancer Risk in Never-Smokers of European Descent is Associated With Genetic Variation in the 5p15.33 TERT-CLPTM1Ll Region. JOURNAL OF THORACIC ONCOLOGY, 14(8), 1360-1369. doi:10.1016/j.jtho.2019.04.008

DOI: 10.1016/j.jtho.2019.04.008

Investigation of Leukocyte Telomere Length and Genetic Variants in Chromosome 5p15.33 as Prognostic Markers in Lung Cancer (Journal article)

Kachuri, L., Helby, J., Bojesen, S. E., Christiani, D. C., Su, L., Wu, X., . . . Hung, R. J. (2019). Investigation of Leukocyte Telomere Length and Genetic Variants in Chromosome 5p15.33 as Prognostic Markers in Lung Cancer. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 28(7), 1228-1237. doi:10.1158/1055-9965.EPI-18-1215

DOI: 10.1158/1055-9965.EPI-18-1215

Immune-mediated genetic pathways resulting in pulmonary function impairment increase lung cancer susceptibility (Report)

Kachuri, L., Johansson, M., Rashkin, S., Graff, R., Bossé, Y., Manem, V., . . . Hung, R. (2019). Immune-mediated genetic pathways resulting in pulmonary function impairment increase lung cancer susceptibility: bioRxiv. doi:10.1101/635318

DOI: 10.1101/635318

Elevated Platelet Count Appears to Be Causally Associated with Increased Risk of Lung Cancer: A Mendelian Randomization Analysis (Journal article)

Zhu, Y., Wei, Y., Zhang, R., Dong, X., Shen, S., Zhao, Y., . . . Christiani, D. C. (2019). Elevated Platelet Count Appears to Be Causally Associated with Increased Risk of Lung Cancer: A Mendelian Randomization Analysis. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 28(5), 935-942. doi:10.1158/1055-9965.EPI-18-0356

DOI: 10.1158/1055-9965.EPI-18-0356

PD-L1 Expression Heterogeneity in NSCLC: Accuracy and Reliability of Using Primary Lung Tumour Versus Metastatic Lymph Node Deposits (Conference Paper)

Haragan, A. K., Field, J. K., Davies, M. P. A., Escriu, C., Gruver, A., & Gosney, J. R. (2019). PD-L1 Expression Heterogeneity in NSCLC: Accuracy and Reliability of Using Primary Lung Tumour Versus Metastatic Lymph Node Deposits. In JOURNAL OF PATHOLOGY Vol. 248 (pp. S11). Retrieved from https://www.webofscience.com/

PD-L1 expression in resected non-small cell lung cancer: variation between primary tumour and nodal metastases (Conference Paper)

Haragan, A., Gosney, J., Field, J., Davies, M., Escriu, C., & Gruver, A. (2019). PD-L1 expression in resected non-small cell lung cancer: variation between primary tumour and nodal metastases. In Journal of Pathology Vol. 248 (pp. S11). Wiley-Blackwell.

Implementation planning for lung cancer screening in China (Journal article)

Cheng, Y. I., Davies, M. P. A., Liu, D., Li, W., & Field, J. K. (2019). Implementation planning for lung cancer screening in China. PRECISION CLINICAL MEDICINE, 2(1), 13-44. doi:10.1093/pcmedi/pbz002

DOI: 10.1093/pcmedi/pbz002

Lung cancer screening programmes: landscape in China (Conference Paper)

Cheng, Y., Davies, M. P. A., Li, W., & Field, J. K. (2019). Lung cancer screening programmes: landscape in China. In LUNG CANCER Vol. 127 (pp. S60-S61). doi:10.1016/S0169-5002(19)30188-6

DOI: 10.1016/S0169-5002(19)30188-6

Systematic analyses of regulatory variants in DNase I hypersensitive sites identified two novel lung cancer susceptibility loci. (Journal article)

Dai, J., Li, Z., Amos, C. I., Hung, R. J., Tardon, A., Andrew, A., . . . Shen, H. (2019). Systematic analyses of regulatory variants in DNase I hypersensitive sites identified two novel lung cancer susceptibility loci.. Carcinogenesis. doi:10.1093/carcin/bgy187

DOI: 10.1093/carcin/bgy187

PD-L1 expression in resected non-small cell lung cancer: variation between primary tumour and nodal metastases (Conference Paper)

Haragan, A., Gosney, J., Field, J. K., Davies, M., Escriu, C., & Gruver, A. (2019). PD-L1 expression in resected non-small cell lung cancer: variation between primary tumour and nodal metastases. In LUNG CANCER Vol. 127 (pp. S25). doi:10.1016/S0169-5002(19)30106-0

DOI: 10.1016/S0169-5002(19)30106-0

2018

Digital Core Needle-Biopsy to Assess PD-L1 Expression in Non-Small Cell Lung Cancer: Optimal Sampling and Need for Re-Biopsy (Conference Paper)

Haragan, A., Field, J., Davies, M., Escriu, C., Gruver, A., & Gosney, J. (2018). Digital Core Needle-Biopsy to Assess PD-L1 Expression in Non-Small Cell Lung Cancer: Optimal Sampling and Need for Re-Biopsy. In JOURNAL OF THORACIC ONCOLOGY Vol. 13 (pp. S534-S535). doi:10.1016/j.jtho.2018.08.739

DOI: 10.1016/j.jtho.2018.08.739

Rare Variants in Known Susceptibility Loci and Their Contribution to Risk of Lung Cancer (Journal article)

Liu, Y., Lusk, C. M., Cho, M. H., Silverman, E. K., Qiao, D., Zhang, R., . . . Spitz, M. R. (2018). Rare Variants in Known Susceptibility Loci and Their Contribution to Risk of Lung Cancer. JOURNAL OF THORACIC ONCOLOGY, 13(10), 1483-1495. doi:10.1016/j.jtho.2018.06.016

DOI: 10.1016/j.jtho.2018.06.016

Utilising Heterogeneity: Using a Digital Database of Lung Cancers and Immune Profile to Complement Subjective Assessment (Conference Paper)

Haragan, A., Field, J., Davies, M., Escriu, C., Gruver, A., & Gosney, J. (2018). Utilising Heterogeneity: Using a Digital Database of Lung Cancers and Immune Profile to Complement Subjective Assessment. In JOURNAL OF THORACIC ONCOLOGY Vol. 13 (pp. S768). doi:10.1016/j.jtho.2018.08.1316

DOI: 10.1016/j.jtho.2018.08.1316

Fine mapping of MHC region in lung cancer highlights independent susceptibility loci by ethnicity (Journal article)

Ferreiro-Iglesias, A., Lesseur, C., McKay, J., Hung, R. J., Han, Y., Zong, X., . . . Brennan, P. (2018). Fine mapping of MHC region in lung cancer highlights independent susceptibility loci by ethnicity. NATURE COMMUNICATIONS, 9, 12 pages. doi:10.1038/s41467-018-05890-2

DOI: 10.1038/s41467-018-05890-2

2017

Common TDP1 Polymorphisms in Relation to Survival among Small Cell Lung Cancer Patients: A Multicenter Study from the International Lung Cancer Consortium (Journal article)

Lohavanichbutr, P., Sakoda, L. C., Amos, C. I., Arnold, S. M., Christiani, D. C., Davies, M. P. A., . . . Chen, C. (2017). Common TDP1 Polymorphisms in Relation to Survival among Small Cell Lung Cancer Patients: A Multicenter Study from the International Lung Cancer Consortium. CLINICAL CANCER RESEARCH, 23(24), 7550-7557. doi:10.1158/1078-0432.CCR-17-1401

DOI: 10.1158/1078-0432.CCR-17-1401

Pleiotropy of genetic variants on obesity and smoking phenotypes: Results from the Oncoarray Project of The International Lung Cancer Consortium (Journal article)

Wang, T., Moon, J. -Y., Wu, Y., Amos, C. I., Hung, R. J., Tardon, A., . . . Ho, G. Y. F. (2017). Pleiotropy of genetic variants on obesity and smoking phenotypes: Results from the Oncoarray Project of The International Lung Cancer Consortium. PLOS ONE, 12(9). doi:10.1371/journal.pone.0185660

DOI: 10.1371/journal.pone.0185660

Common TDP1 polymorphisms in relation to survival among small cell lung cancer patients in a multicenter study from the International Lung Cancer Consortium (Conference Paper)

Lohavanichbutr, P., Sakoda, L. C., Amos, C. I., Arnold, S. M., Christiani, D. C., Davies, M. P., . . . Chen, C. (2017). Common TDP1 polymorphisms in relation to survival among small cell lung cancer patients in a multicenter study from the International Lung Cancer Consortium. In CANCER RESEARCH Vol. 77. doi:10.1158/1538-7445.AM2017-2248

DOI: 10.1158/1538-7445.AM2017-2248

Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes (Journal article)

McKay, J. D., Hung, R. J., Han, Y., Zong, X., Carreras-Torres, R., Christiani, D. C., . . . Field, J. K. (2017). Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.. Nature Genetics, 49(7), 1126-1132. doi:10.1038/ng.3892

DOI: 10.1038/ng.3892

AURKA mRNA expression is an independent predictor of poor prognosis in patients with non-small cell lung cancer (Journal article)

Al-Khafaji, A. S. K., Marcus, M. W., Davies, M. P. A., Risk, J. M., Shaw, R. J., Field, J. K., & Liloglou, T. (2017). AURKA mRNA expression is an independent predictor of poor prognosis in patients with non-small cell lung cancer. Oncology letters, 13(6), 4463-4468. doi:10.3892/ol.2017.6012

DOI: 10.3892/ol.2017.6012

Obesity, metabolic factors and risk of different histological types of lung cancer: A Mendelian randomization study (Journal article)

Carreras-Torres, R., Johansson, M., Haycock, P. C., Wade, K. H., Relton, C. L., Martin, R. M., . . . Brennan, P. (2017). Obesity, metabolic factors and risk of different histological types of lung cancer: A Mendelian randomization study. PLOS ONE, 12(6). doi:10.1371/journal.pone.0177875

DOI: 10.1371/journal.pone.0177875

Aurora B expression modulates paclitaxel response in non-small cell lung cancer. (Journal article)

Al-Khafaji, A. S., Davies, M. P., Risk, J. M., Marcus, M. W., Koffa, M., Gosney, J. R., . . . Liloglou, T. (2017). Aurora B expression modulates paclitaxel response in non-small cell lung cancer.. British journal of cancer, 116(05), 592-599. doi:10.1038/bjc.2016.453

DOI: 10.1038/bjc.2016.453

The Non-Invasive LuCED® Test for Detection of Early Stage Lung Cancer (Conference Paper)

Meyer, M., Bell, T., Sussman, D., Wilbur, D., Presley, C., Hayenga, J., . . . Nelson, A. (2017). The Non-Invasive LuCED® Test for Detection of Early Stage Lung Cancer. In JOURNAL OF THORACIC ONCOLOGY Vol. 12 (pp. S343-S344). doi:10.1016/j.jtho.2016.11.375

DOI: 10.1016/j.jtho.2016.11.375

2016

The causal relevance of body mass index in different histological types of lung cancer: A Mendelian randomization study (Journal article)

Carreras-Torres, R., Haycock, P. C., Relton, C. L., Martin, R. M., Smith, G. D., Kraft, P., . . . Brennan, P. (2016). The causal relevance of body mass index in different histological types of lung cancer: A Mendelian randomization study. SCIENTIFIC REPORTS, 6. doi:10.1038/srep31121

DOI: 10.1038/srep31121

Silicon Nanowire Sensors Enable Diagnosis of Patients via Exhaled Breath (Journal article)

Shehada, N., Cancilla, J. C., Torrecilla, J. S., Pariente, E. S., Broenstrup, G., Christiansen, S., . . . Haick, H. (2016). Silicon Nanowire Sensors Enable Diagnosis of Patients via Exhaled Breath. ACS NANO, 10(7), 7047-7057. doi:10.1021/acsnano.6b03127

DOI: 10.1021/acsnano.6b03127

Fine mapping of chromosome 5p15.33 based on a targeted deep sequencing and high density genotyping identifies novel lung cancer susceptibility loci (Journal article)

Kachuri, L., Amos, C. I., Mckay, J. D., Johansson, M., Vineis, P., Bueno-de-Mesquita, H. B., . . . Hung, R. J. (2016). Fine mapping of chromosome 5p15.33 based on a targeted deep sequencing and high density genotyping identifies novel lung cancer susceptibility loci. CARCINOGENESIS, 37(1), 96-105. doi:10.1093/carcin/bgv165

DOI: 10.1093/carcin/bgv165

2015

Differentiation between genetic mutations of breast cancer by breath volatolomics (Journal article)

Barash, O., Zhang, W., Halpern, J. M., Hua, Q. -L., Pan, Y. -Y., Kayal, H., . . . Haick, H. (2015). Differentiation between genetic mutations of breast cancer by breath volatolomics. ONCOTARGET, 6(42), 44864-44876. doi:10.18632/oncotarget.6269

DOI: 10.18632/oncotarget.6269

Associated Links Among Smoking, Chronic Obstructive Pulmonary Disease, and Small Cell Lung Cancer: A Pooled Analysis in the International Lung Cancer Consortium (Journal article)

Huang, R., Wei, Y., Hung, R. J., Liu, G., Su, L., Zhang, R., . . . Christiani, D. C. (2015). Associated Links Among Smoking, Chronic Obstructive Pulmonary Disease, and Small Cell Lung Cancer: A Pooled Analysis in the International Lung Cancer Consortium. EBIOMEDICINE, 2(11), 1677-1685. doi:10.1016/j.ebiom.2015.09.031

DOI: 10.1016/j.ebiom.2015.09.031

Identification of lung cancer histology-specific variants applying Bayesian framework variant prioritization approaches within the TRICL and ILCCO consortia (Journal article)

Brenner, D. R., Amos, C. I., Brhane, Y., Timofeeva, M. N., Caporaso, N., Wang, Y., . . . Hung, R. J. (2015). Identification of lung cancer histology-specific variants applying Bayesian framework variant prioritization approaches within the TRICL and ILCCO consortia. Carcinogenesis, 36(11), 1314-1326. doi:10.1093/carcin/bgv128

DOI: 10.1093/carcin/bgv128

Lung cancer trend in England for the period of 2002 to 2011 and projections of future burden until 2020 (Journal article)

Olajide, O. O., Field, J. K., Davies, M. M. P. A., & Marcus, M. W. (2015). Lung cancer trend in England for the period of 2002 to 2011 and projections of future burden until 2020. INTERNATIONAL JOURNAL OF ONCOLOGY, 47(2), 739-746. doi:10.3892/ijo.2015.3049

DOI: 10.3892/ijo.2015.3049

Lung cancer trend in England for the period of 2002 to 2011 and projections of future burden until 2020 (Journal article)

OLAJIDE, O. O., FIELD, J. K., DAVIES, M. M. P. A., & MARCUS, M. W. (2015). Lung cancer trend in England for the period of 2002 to 2011 and projections of future burden until 2020. International Journal of Oncology, 47(2), 739-746. doi:10.3892/ijo.2015.3049

DOI: 10.3892/ijo.2015.3049

Application of SureSeq solid tumour panel sequencing to a panel of FFPE samples of non small cell lung cancer from the Liverpool lung project (Conference Paper)

Hyde, R., Davies, M. P. A., Gosney, J., & Field, J. (2015). Application of SureSeq solid tumour panel sequencing to a panel of FFPE samples of non small cell lung cancer from the Liverpool lung project. In LUNG CANCER Vol. 87 (pp. S5). doi:10.1016/S0169-5002(15)50011-1

DOI: 10.1016/S0169-5002(15)50011-1

Volatile biomarkers for discrimination of lung cancer risk and mutation (Conference Paper)

Davies, M. P. A., Barash, O., Jeries, R., Peled, N., Ilouze, M., Hyde, R., . . . Field, J. (2015). Volatile biomarkers for discrimination of lung cancer risk and mutation. In LUNG CANCER Vol. 87 (pp. S4-S5). doi:10.1016/S0169-5002(15)50010-X

DOI: 10.1016/S0169-5002(15)50010-X

2014

Unique volatolomic signatures of TP53 and KRAS in lung cells (Journal article)

Davies, M. P. A., Barash, O., Jeries, R., Peled, N., Ilouze, M., Hyde, R., . . . Haick, H. (2014). Unique volatolomic signatures of TP53 and KRAS in lung cells. BRITISH JOURNAL OF CANCER, 111(6), 1213-1221. doi:10.1038/bjc.2014.411

DOI: 10.1038/bjc.2014.411

Frequent mutations in chromatin-remodelling genes in pulmonary carcinoids (Journal article)

Fernandez-Cuesta, L., Peifer, M., Lu, X., Sun, R., Ozretic, L., Seidel, D., . . . Thomas, R. K. (2014). Frequent mutations in chromatin-remodelling genes in pulmonary carcinoids. NATURE COMMUNICATIONS, 5. doi:10.1038/ncomms4518

DOI: 10.1038/ncomms4518

Epigenetic biomarkers in lung cancer (Journal article)

Liloglou, T., Bediaga, N. G., Brown, B. R. B., Field, J. K., & Davies, M. P. A. (2014). Epigenetic biomarkers in lung cancer. CANCER LETTERS, 342(2), 200-212. doi:10.1016/j.canlet.2012.04.018

DOI: 10.1016/j.canlet.2012.04.018

2013

A Prognostic DNA Methylation Signature for Stage I Non-Small-Cell Lung Cancer (Journal article)

Sandoval, J., Mendez-Gonzalez, J., Nadal, E., Chen, G., Carmona, F. J., Sayols, S., . . . Esteller, M. (2013). A Prognostic DNA Methylation Signature for Stage I Non-Small-Cell Lung Cancer. JOURNAL OF CLINICAL ONCOLOGY, 31(32), 4140-+. doi:10.1200/JCO.2012.48.5516

DOI: 10.1200/JCO.2012.48.5516

A microRNA-based prediction algorithm for diagnosis of non-small lung cell carcinoma in minimal biopsy material (Journal article)

Bediaga, N. G., Davies, M. P. A., Acha-Sagredo, A., Hyde, R., Raji, O. Y., Page, R., . . . Liloglou, T. (2013). A microRNA-based prediction algorithm for diagnosis of non-small lung cell carcinoma in minimal biopsy material. BRITISH JOURNAL OF CANCER, 109(9), 2404-2411. doi:10.1038/bjc.2013.623

DOI: 10.1038/bjc.2013.623

2012

PRE-clinical investigation of AT7519, a novel CDK inhibitor, as a potential therapeutic agent in pancreatic cancer (Journal article)

Thomas, A., Shaw, E., Ghaneh, P., Greenhalf, W., Davies, M., Costello, E., . . . Neoptolemos, J. P. (2012). PRE-clinical investigation of AT7519, a novel CDK inhibitor, as a potential therapeutic agent in pancreatic cancer. Pancreatology, 12(3), e10. doi:10.1016/j.pan.2012.03.023

DOI: 10.1016/j.pan.2012.03.023

Pre-clinical assessment of AT13387, an HSP90 inhibitor, in a pancreatic cancer xenograft model (Journal article)

Shaw, E., Thomas, A., Ghaneh, P., Greenhalf, W., Davies, M., Costello, E., . . . Sibson, D. R. (2012). Pre-clinical assessment of AT13387, an HSP90 inhibitor, in a pancreatic cancer xenograft model. Pancreatology, 12(3), e7-e8. doi:10.1016/j.pan.2012.03.020

DOI: 10.1016/j.pan.2012.03.020

MicroRNAs for early detection of lung cancer (Journal article)

Bediaga, N., Davies, M. P. A., Raji, O. Y., Alfirevic, A., Liloglou, T., & Field, J. K. (2012). MicroRNAs for early detection of lung cancer. CANCER RESEARCH, 72. doi:10.1158/1538-7445.AM2012-4133

DOI: 10.1158/1538-7445.AM2012-4133

2010

Expression of the rat calcium-binding protein p9Ka in transgenic mice. (Thesis / Dissertation)

Davies, M. P. A. (2010). Expression of the rat calcium-binding protein p9Ka in transgenic mice..

Microarray analysis of suppression subtracted hybridisation libraries identifies genes associated with breast cancer progression (Journal article)

Barraclough, D. L., Sewart, S., Rudland, P. S., Shoker, B. S., Sibson, D. R., Barraclough, R., & Davies, M. P. A. (2010). Microarray analysis of suppression subtracted hybridisation libraries identifies genes associated with breast cancer progression. CELLULAR ONCOLOGY, 32(1-2), 87-99. doi:10.3233/CLO-2009-0499

DOI: 10.3233/CLO-2009-0499

Microarray Analysis of Suppression Subtracted Hybridisation Libraries Identifies Genes Associated with Breast Cancer Progression (Journal article)

Barraclough, D. L., Sewart, S., Rudland, P. S., Shoker, B. S., Sibson, D. R., Barraclough, R., & Davies, M. P. A. (2010). Microarray Analysis of Suppression Subtracted Hybridisation Libraries Identifies Genes Associated with Breast Cancer Progression. Analytical Cellular Pathology, 32(1-2), 87-99. doi:10.1155/2010/582416

DOI: 10.1155/2010/582416

2008

Expression and splicing of the unfolded protein response gene XBP-1 are sieniticantly associated with clinical outcome of endocrine-treated breast cancer (Journal article)

Davies, M. P. A., Barraclough, D. L., Stewart, C., Joyce, K. A., Eccles, R. M., Barraclough, R., . . . Sibson, D. R. (2008). Expression and splicing of the unfolded protein response gene XBP-1 are sieniticantly associated with clinical outcome of endocrine-treated breast cancer. INTERNATIONAL JOURNAL OF CANCER, 123(1), 85-88. doi:10.1002/ijc.23479

DOI: 10.1002/ijc.23479

2007

Association of oestrogen receptor beta 2 (ERβ2/ERβcx) with outcome of adjuvant endocrine treatment for primary breast cancer -: a retrospective study (Journal article)

Vinayagam, R., Sibson, D. R., Holcombe, C., Aachi, V., & Davies, M. P. (2007). Association of oestrogen receptor beta 2 (ERβ2/ERβcx) with outcome of adjuvant endocrine treatment for primary breast cancer -: a retrospective study. BMC CANCER, 7. doi:10.1186/1471-2407-7-131

DOI: 10.1186/1471-2407-7-131

2006

Significance of the metastasis-inducing protein AGR2 for outcome in hormonally treated breast cancer patients (Journal article)

Innes, H. E., Liu, D., Barraclough, R., Davies, M. P. A., O'Neill, P. A., Platt-Higgins, A., . . . Rudland, P. S. (2006). Significance of the metastasis-inducing protein AGR2 for outcome in hormonally treated breast cancer patients. BRITISH JOURNAL OF CANCER, 94(7), 1057-1065. doi:10.1038/sj.bjc.6603065

DOI: 10.1038/sj.bjc.6603065

2005

Hypersensitive K303R oestrogen receptor-α variant not found in invasive carcinomas (Journal article)

Davies, M. P. A., O'Neill, P. A., Innes, H., & Sibson, D. R. (2005). Hypersensitive K303R oestrogen receptor-α variant not found in invasive carcinomas. BREAST CANCER RESEARCH, 7(1), R113-R118. doi:10.1186/bcr965

DOI: 10.1186/bcr965

2004

Correlation of mRNA for oestrogen receptor beta splice variants ERβ1, ERβ2/ERβcx and ERβ5 with outcome in endocrine-treated breast cancer (Journal article)

Davies, M. P. A., O'Neill, P. A., Innes, H., Sibson, D. R., Prime, W., Holcombe, C., & Foster, C. S. (2004). Correlation of mRNA for oestrogen receptor beta splice variants ERβ1, ERβ2/ERβcx and ERβ5 with outcome in endocrine-treated breast cancer. JOURNAL OF MOLECULAR ENDOCRINOLOGY, 33(3), 773-782. doi:10.1677/jme.1.01574

DOI: 10.1677/jme.1.01574

Wild-type oestrogen receptor beta (ERb1) mRNA and protein expression in Tamoxifen-treated post-menopausal breast cancers (Journal article)

O'Neill, P. A., Davies, M. P. A., Shaaban, A. M., Innes, H., Torevell, A., Sibson, D. R., & Foster, C. S. (2004). Wild-type oestrogen receptor beta (ERb1) mRNA and protein expression in Tamoxifen-treated post-menopausal breast cancers. BRITISH JOURNAL OF CANCER, 91(9), 1694-1702. doi:10.1038/sj.bjc.6602183

DOI: 10.1038/sj.bjc.6602183

Increased risk of malignant progression in benign proliferating breast lesions defined by expression of heat shock protein 27 (Journal article)

O'Neill, P. A., Shaaban, A. M., West, C. R., Dodson, A., Jarvis, C., Moore, P., . . . Foster, C. S. (2004). Increased risk of malignant progression in benign proliferating breast lesions defined by expression of heat shock protein 27. BRITISH JOURNAL OF CANCER, 90(1), 182-188. doi:10.1038/sj.bjc.6601449

DOI: 10.1038/sj.bjc.6601449

2003

Declining estrogen receptor-β expression defines malignant progression of human breast neoplasia (Journal article)

Shaaban, A. M., O'Neill, P. A., Davies, M. P. A., Sibson, R., West, C. R., Smith, P. H., & Foster, C. S. (2003). Declining estrogen receptor-β expression defines malignant progression of human breast neoplasia. AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 27(12), 1502-1512. doi:10.1097/00000478-200312000-00002

DOI: 10.1097/00000478-200312000-00002

Examination of tumour histopathology and gene expression in a neu/S100A4 transgenic model of metastatic breast cancer (Journal article)

Simpson, P. T., Shoker, B. S., Barraclough, R., Halliwell, N., Rudland, P. S., Sibson, D. R., & Davies, M. P. A. (2003). Examination of tumour histopathology and gene expression in a neu/S100A4 transgenic model of metastatic breast cancer. INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY, 84(4), 173-183. doi:10.1046/j.1365-2613.2003.00350.x

DOI: 10.1046/j.1365-2613.2003.00350.x

2002

Molecular and genetic abnormalities in radial scar (Journal article)

Iqbal, M., Shoker, B. S., Foster, C. S., Jarvis, C., Sibson, D. R., & Davies, M. P. A. (2002). Molecular and genetic abnormalities in radial scar. HUMAN PATHOLOGY, 33(7), 715-722. doi:10.1053/hupa.2002.125375

DOI: 10.1053/hupa.2002.125375

2001

Hypersensitive K303R oestrogen receptor variant not found in ductal carcinoma in situ (Journal article)

Davies, M. P. A., Iqbal, M., Shoker, B. S., & Sibson, D. R. (2001). Hypersensitive K303R oestrogen receptor variant not found in ductal carcinoma in situ. European Journal of Cancer, 37, 29. doi:10.1016/s0959-8049(01)80116-7

DOI: 10.1016/s0959-8049(01)80116-7

Immunodetectable cyclin D1 is associated with oestrogen receptor but not Ki67 in normal, cancerous and precancerous breast lesions (Journal article)

Shoker, B. S., Jarvis, C., Davies, M. P. A., Iqbal, M., Sibson, D. R., & Sloane, J. P. (2001). Immunodetectable cyclin D1 is associated with oestrogen receptor but not Ki67 in normal, cancerous and precancerous breast lesions. BRITISH JOURNAL OF CANCER, 84(8), 1064-1069. doi:10.1054/bjoc.2001.1705

DOI: 10.1054/bjoc.2001.1705

Characterisation of molecular alterations in microdissected archival gliomas (Journal article)

Walker, C., Joyce, K. A., Thompson-Hehir, J., Davies, M. P. A., Gibbs, F. E. M., Halliwell, N., . . . Rossi, M. L. (2001). Characterisation of molecular alterations in microdissected archival gliomas. ACTA NEUROPATHOLOGICA, 101(4), 321-333. Retrieved from https://www.webofscience.com/

Subgroups of non-atypical hyperplasia of breast defined by proliferation of oestrogen receptor-positive cells (Journal article)

Iqbal, M., Davies, M. P. A., Shoker, B. S., Jarvis, C., Sibson, D. R., & Sloane, J. P. (2001). Subgroups of non-atypical hyperplasia of breast defined by proliferation of oestrogen receptor-positive cells. JOURNAL OF PATHOLOGY, 193(3), 333-338. doi:3.0.CO;2-#">10.1002/1096-9896(2000)9999:9999<::AID-PATH801>3.0.CO;2-#

DOI: 10.1002/1096-9896(2000)9999:9999<::AID-PATH801>3.0.CO;2-#

2000

Abnormal regulation of the oestrogen receptor in benign breast lesions (Journal article)

Shoker, B. S., Jarvis, C., Clarke, R. B., Anderson, E., Munro, C., Davies, M. P. A., . . . Sloane, J. P. (2000). Abnormal regulation of the oestrogen receptor in benign breast lesions. JOURNAL OF CLINICAL PATHOLOGY, 53(10), 778-783. doi:10.1136/jcp.53.10.778

DOI: 10.1136/jcp.53.10.778

Novel polymerase chain reaction approach for full-coding p53 mutation detection in microdissected archival tumors (Journal article)

Thompson-Hehir, J., Davies, M. P. A., Green, J. A., Halliwell, N., Joyce, K. A., Salisbury, J., . . . Walker, C. (2000). Novel polymerase chain reaction approach for full-coding p53 mutation detection in microdissected archival tumors. DIAGNOSTIC MOLECULAR PATHOLOGY, 9(2), 110-119. doi:10.1097/00019606-200006000-00007

DOI: 10.1097/00019606-200006000-00007

1999

Estrogen receptor-positive proliferating cells in the normal and precancerous breast (Journal article)

Shoker, B. S., Jarvis, C., Clarke, R. B., Anderson, E., Hewlett, J., Davies, M. P. A., . . . Sloane, J. P. (1999). Estrogen receptor-positive proliferating cells in the normal and precancerous breast. AMERICAN JOURNAL OF PATHOLOGY, 155(6), 1811-1815. doi:10.1016/S0002-9440(10)65498-3

DOI: 10.1016/S0002-9440(10)65498-3

Mutation in the PTEN/MMAC1 gene in archival low grade and high grade gliomas (Journal article)

Davies, M. P. A., Gibbs, F. E. M., Halliwell, N., Joyce, K. A., Roebuck, M. M., Rossi, M. L., . . . Walker, C. (1999). Mutation in the PTEN/MMAC1 gene in archival low grade and high grade gliomas. BRITISH JOURNAL OF CANCER, 79(9-10), 1542-1548. doi:10.1038/sj.bjc.6690246

DOI: 10.1038/sj.bjc.6690246

1998

Use of DNA transfer in the induction of metastasis in experimental mammary systems (Journal article)

Barraclough, R., Chen, H. J., Davies, B. R., Davies, M. P. A., Ke, Y. Q., Lloyd, B. H., . . . Rudland, P. S. (1998). Use of DNA transfer in the induction of metastasis in experimental mammary systems. MAMMARY DEVELOPMENT IN CANCER, (63), 273-294. Retrieved from https://www.webofscience.com/

1997

Transcriptional down-regulation of the metastasis-inducing S100A4 (p9Ka) in benign but not in malignant rat mammary epithelial cells by GC-factor (Journal article)

Chen, D. S., Davies, M. P. A., Rudland, P. S., & Barraclough, R. (1997). Transcriptional down-regulation of the metastasis-inducing S100A4 (p9Ka) in benign but not in malignant rat mammary epithelial cells by GC-factor. JOURNAL OF BIOLOGICAL CHEMISTRY, 272(32), 20283-20290. doi:10.1074/jbc.272.32.20283

DOI: 10.1074/jbc.272.32.20283

Elevated expression of calcium-binding protein p9Ka is associated with increasing malignant characteristics of rat prostate carcinoma cells (Journal article)

Ke, Y. Q., Jing, C., Barraclough, R., Smith, P., Davies, M. P. A., & Foster, C. S. (1997). Elevated expression of calcium-binding protein p9Ka is associated with increasing malignant characteristics of rat prostate carcinoma cells. INTERNATIONAL JOURNAL OF CANCER, 71(5), 832-837. doi:3.0.CO;2-8">10.1002/(SICI)1097-0215(19970529)71:5<832::AID-IJC22>3.0.CO;2-8

DOI: 10.1002/(SICI)1097-0215(19970529)71:5<832::AID-IJC22>3.0.CO;2-8

1996

Expression of the calcium-binding protein S100A4 (p9Ka) in MMTV-neu transgenic mice induces metastasis of mammary tumours (Journal article)

Davies, M. P. A., Rudland, P. S., Robertson, L., Parry, E. W., Jolicoeur, P., & Barraclough, R. (1996). Expression of the calcium-binding protein S100A4 (p9Ka) in MMTV-neu transgenic mice induces metastasis of mammary tumours. ONCOGENE, 13(8), 1631-1637. Retrieved from https://www.webofscience.com/

Growth & mammary abnormalities in mice containing an altered calcium-binding protein transgene (Journal article)

Davies, M. P. A., Harris, S., Rudland, P. S., & Barraclough, R. (1996). Growth & mammary abnormalities in mice containing an altered calcium-binding protein transgene. BIOCHEMICAL SOCIETY TRANSACTIONS, 24(3), S356. doi:10.1042/bst024356s

DOI: 10.1042/bst024356s

1995

EXPRESSION OF THE RAT, S-100-RELATED, CALCIUM-BINDING PROTEIN GENE, P9KA, IN TRANSGENIC MICE DEMONSTRATES DIFFERENT PATTERNS OF EXPRESSION BETWEEN THESE 2 SPECIES (Journal article)

DAVIES, M., HARRIS, S., RUDLAND, P., & BARRACLOUGH, R. (1995). EXPRESSION OF THE RAT, S-100-RELATED, CALCIUM-BINDING PROTEIN GENE, P9KA, IN TRANSGENIC MICE DEMONSTRATES DIFFERENT PATTERNS OF EXPRESSION BETWEEN THESE 2 SPECIES. DNA AND CELL BIOLOGY, 14(10), 825-832. doi:10.1089/dna.1995.14.825

DOI: 10.1089/dna.1995.14.825

1993

Induction of the metastatic phenotype in rat mammary benign tumour cells by the gene for p9Ka a novel calcium-binding protein (Journal article)

Barraclough, R., Davies, B. R., Davies, M. P. A., Gibbs, F. E. M., & Rudland, P. S. (1993). Induction of the metastatic phenotype in rat mammary benign tumour cells by the gene for p9Ka a novel calcium-binding protein. The Breast, 2(3), 191. doi:10.1016/0960-9776(93)90090-3

DOI: 10.1016/0960-9776(93)90090-3

INDUCTION OF THE METASTATIC PHENOTYPE BY TRANSFECTION OF A BENIGN RAT MAMMARY EPITHELIAL-CELL LINE WITH THE GENE FOR P9KA, A RAT CALCIUM-BINDING PROTEIN, BUT NOT WITH THE ONCOGENE EJ-RAS-1 (Journal article)

DAVIES, B. R., DAVIES, M. P. A., GIBBS, F. E. M., BARRACLOUGH, R., & RUDLAND, P. S. (1993). INDUCTION OF THE METASTATIC PHENOTYPE BY TRANSFECTION OF A BENIGN RAT MAMMARY EPITHELIAL-CELL LINE WITH THE GENE FOR P9KA, A RAT CALCIUM-BINDING PROTEIN, BUT NOT WITH THE ONCOGENE EJ-RAS-1. ONCOGENE, 8(4), 999-1008. Retrieved from https://www.webofscience.com/

PRODUCTION OF THE METASTATIC PHENOTYPE BY DNA TRANSFECTION IN A RAT MAMMARY MODEL (Journal article)

DAVIES, B. R., BARRACLOUGH, R., DAVIES, M. P. A., & RUDLAND, P. S. (1993). PRODUCTION OF THE METASTATIC PHENOTYPE BY DNA TRANSFECTION IN A RAT MAMMARY MODEL. CELL BIOLOGY INTERNATIONAL, 17(9), 871-879. doi:10.1006/cbir.1993.1150

DOI: 10.1006/cbir.1993.1150

1990

USE OF FLUO-3 TO MEASURE CYTOSOLIC CA-2+ IN PLATELETS AND NEUTROPHILS - LOADING CELLS WITH THE DYE, CALIBRATION OF TRACES, MEASUREMENTS IN THE PRESENCE OF PLASMA, AND BUFFERING OF CYTOSOLIC CA-2+ (Journal article)

MERRITT, J. E., MCCARTHY, S. A., DAVIES, M. P. A., & MOORES, K. E. (1990). USE OF FLUO-3 TO MEASURE CYTOSOLIC CA-2+ IN PLATELETS AND NEUTROPHILS - LOADING CELLS WITH THE DYE, CALIBRATION OF TRACES, MEASUREMENTS IN THE PRESENCE OF PLASMA, AND BUFFERING OF CYTOSOLIC CA-2+. BIOCHEMICAL JOURNAL, 269(2), 513-519. doi:10.1042/bj2690513

DOI: 10.1042/bj2690513

A ROLE FOR CALCIUM AND PROTEIN KINASE-C IN AGONIST-STIMULATED ADHESION OF HUMAN NEUTROPHILS (Journal article)

DAVIES, M. P. A., HALLAM, T. J., & MERRITT, J. E. (1990). A ROLE FOR CALCIUM AND PROTEIN KINASE-C IN AGONIST-STIMULATED ADHESION OF HUMAN NEUTROPHILS. BIOCHEMICAL JOURNAL, 267(1), 13-16. doi:10.1042/bj2670013

DOI: 10.1042/bj2670013

1989

A ROLE FOR CYTOPLASMIC CALCIUM IN THE STIMULATION OF NEUTROPHIL ADHESION (Journal article)

DAVIES, M. P. A., MOORES, K. E., & MERRITT, J. E. (1989). A ROLE FOR CYTOPLASMIC CALCIUM IN THE STIMULATION OF NEUTROPHIL ADHESION. BIOCHEMICAL SOCIETY TRANSACTIONS, 17(1), 123. doi:10.1042/bst0170123

DOI: 10.1042/bst0170123

Publications

Selected Publications

2024

Lung cancer in ever- and never-smokers: findings from multi-population GWAS studies. (Journal article)

2023

Identification of genetically predicted DNA methylation markers associated with non-small cell lung cancer risk among 34,964 cases and 448,579 controls. (Journal article)

Large-scale whole exome sequencing studies identify two genes,CTSL and APOE, associated with lung cancer. (Journal article)

Association between duration of smoking abstinence before non-small-cell lung cancer diagnosis and survival: a retrospective, pooled analysis of cohort studies (Journal article)

Non-coding RNA-directed therapeutics in lung cancer: Delivery technologies and clinical applications (Journal article)

Candidate pathway analysis of surfactant proteins identifies CTSH and SFTA2 that influences lung cancer risk. (Journal article)

Plasma protein biomarkers for early prediction of lung cancer (Journal article)

Circulating Proteome for Pulmonary Nodule Malignancy. (Journal article)

Mosaic chromosomal alterations is associated with increased lung cancer risk: insight from the INTEGRAL-ILCCO cohort analysis. (Journal article)

Design and methodological considerations for biomarker discovery and validation in the Integrative Analysis of Lung Cancer Etiology and Risk (INTEGRAL) Program (Journal article)

On the Non-Linearity of Radon-Induced Lung Cancer (Preprint)

2022

On the non-linearity of radon-induced lung cancer (Preprint)

On the non-linearity of radon-induced lung cancer (Preprint)

Circulating Proteome for Pulmonary Nodule Malignancy (Preprint)

EP01.06-006 Impact of Low Dose CT Screening on Cause of Death in Different Socio-Economic Groups (Journal article)

Genome-wide interaction analysis identified low-frequency variants with sex disparity in lung cancer risk (Journal article)

On the non-linearity of radon-induced lung cancer (Preprint)

Design and methodological considerations for biomarker discovery and validation in the Integrative Analysis of Lung Cancer Etiology and Risk (INTEGRAL) Program (Preprint)

Impact of risk-based low dose CT screening on different socio-economic groups (Journal article)

Gene-gene interaction of <i>AhR</i>with and within the <i>Wnt</i>cascade affects susceptibility to lung cancer (Journal article)

Iam hiQ-a novel pair of accuracy indices for imputed genotypes (Journal article)

Accounting for EGFR mutations in epidemiological analyses of non-small cell lung cancers: Examples based on the International Lung Cancer Consortium data. (Journal article)

Impact of Low Dose CT Screening on Cause of Death in Different Socio-Economic Groups (Conference Paper)

2021

Lung cancer mortality reduction by LDCT screening: UKLS randomised trial results and international meta-analysis (Journal article)

OA19.02 The UKLS Trial Outcome Results: Lung Cancer Mortality Reduction by LDCT Screening Confirmed in an International Meta-Analysis (Journal article)

Gene-gene Interaction of AhR with and within the Wnt Cascade Affects Susceptibility to Lung Cancer (Preprint)

Genome-wide interaction analysis identified low-frequency variants with sex disparity in lung cancer risk (Preprint)

Gene-gene Interaction of AhR With and Within the Wnt Cascade Affects Susceptibility to Lung Cancer (Preprint)

Lung cancer risk in painters: results from the SYNERGY pooled case-control study consortium (Journal article)

FP07.02 Deep Learning Based Analysis of Multiplex IHC Accurately Interprets PD-L1 and Provides Prognostic Information in NSCLC (Journal article)

FP09.02 Calibration of the LLP Lung Cancer Risk Stratification Model: Prospective Validation in the UKLS Cohort of 76,000 People (Journal article)

Rare deleterious germline variants and risk of lung cancer (Journal article)

Liverpool Lung Project lung cancer risk stratification model: calibration and prospective validation (Journal article)

The relationship between body-mass index and overall survival in non-small cell lung cancer by sex, smoking status, and race: A pooled analysis of 20,937 International lung Cancer consortium (ILCCO) patients (Journal article)

2020

Protein-altering germline mutations implicate novel genes related to lung cancer development (Journal article)

Long non-coding RNA dysregulation is a frequent event in non-small cell lung carcinoma pathogenesis (Journal article)

Immune-mediated genetic pathways resulting in pulmonary function impairment increase lung cancer susceptibility (Journal article)

2019

Potential genetic modifiers for somatic EGFR mutation in lung cancer: a meta-analysis and literature review (Journal article)

The Role of Autophagy in Lung Disease (Chapter)

Implementation Planning of Lung Cancer Screening in China (Conference Paper)

Pathogenic Germline Rare Variants and Risk of Lung Cancer (Conference Paper)

Body Mass Index (BMI), BMI Change, and Overall Survival in Patients With SCLC and NSCLC: A Pooled Analysis of the International Lung Cancer Consortium (Journal article)

Heterogeneity of PD-L1 expression in non-small cell lung cancer: Implications for specimen sampling in predicting treatment response (Journal article)

Lung Cancer Risk in Never-Smokers of European Descent is Associated With Genetic Variation in the 5<sub>p</sub>15.33 <i>TERT-CLPTM1Ll</i> Region (Journal article)

Investigation of Leukocyte Telomere Length and Genetic Variants in Chromosome 5p15.33 as Prognostic Markers in Lung Cancer (Journal article)

Immune-mediated genetic pathways resulting in pulmonary function impairment increase lung cancer susceptibility (Report)

Elevated Platelet Count Appears to Be Causally Associated with Increased Risk of Lung Cancer: A Mendelian Randomization Analysis (Journal article)

PD-L1 Expression Heterogeneity in NSCLC: Accuracy and Reliability of Using Primary Lung Tumour Versus Metastatic Lymph Node Deposits (Conference Paper)

PD-L1 expression in resected non-small cell lung cancer: variation between primary tumour and nodal metastases (Conference Paper)

Implementation planning for lung cancer screening in China (Journal article)

Lung cancer screening programmes: landscape in China (Conference Paper)

Systematic analyses of regulatory variants in DNase I hypersensitive sites identified two novel lung cancer susceptibility loci. (Journal article)

PD-L1 expression in resected non-small cell lung cancer: variation between primary tumour and nodal metastases (Conference Paper)

2018

Digital Core Needle-Biopsy to Assess PD-L1 Expression in Non-Small Cell Lung Cancer: Optimal Sampling and Need for Re-Biopsy (Conference Paper)

Rare Variants in Known Susceptibility Loci and Their Contribution to Risk of Lung Cancer (Journal article)

Utilising Heterogeneity: Using a Digital Database of Lung Cancers and Immune Profile to Complement Subjective Assessment (Conference Paper)

Fine mapping of MHC region in lung cancer highlights independent susceptibility loci by ethnicity (Journal article)

2017

Common TDP1 Polymorphisms in Relation to Survival among Small Cell Lung Cancer Patients: A Multicenter Study from the International Lung Cancer Consortium (Journal article)

Pleiotropy of genetic variants on obesity and smoking phenotypes: Results from the Oncoarray Project of The International Lung Cancer Consortium (Journal article)

Common TDP1 polymorphisms in relation to survival among small cell lung cancer patients in a multicenter study from the International Lung Cancer Consortium (Conference Paper)

Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes (Journal article)

AURKA mRNA expression is an independent predictor of poor prognosis in patients with non-small cell lung cancer (Journal article)

Obesity, metabolic factors and risk of different histological types of lung cancer: A Mendelian randomization study (Journal article)

Aurora B expression modulates paclitaxel response in non-small cell lung cancer. (Journal article)

The Non-Invasive LuCED® Test for Detection of Early Stage Lung Cancer (Conference Paper)

2016

The causal relevance of body mass index in different histological types of lung cancer: A Mendelian randomization study (Journal article)

Silicon Nanowire Sensors Enable Diagnosis of Patients <i>via</i> Exhaled Breath (Journal article)

Fine mapping of chromosome 5p15.33 based on a targeted deep sequencing and high density genotyping identifies novel lung cancer susceptibility loci (Journal article)

2015