Photo of Prof Calum Semple


Professor in Child Health and Outbreak Medicine, Consultant Respiratory Paediatrician at Alder Hey Children's Hospital Women's and Children's Health


Personal Statement

Professor Calum Semple came to Liverpool in 1999 after training in London and Oxford. His doctoral research was in clinical virology and funded by an MRC - Burroughs Wellcome Industrial Fellowship. He was converted to paediatrics by inspiring clinical teachers at Oxford and later persuaded to sub-specialise with the renowned respiratory team at Alder Hey Children’s Hospital.

An NIHR National Clinician Scientist Award in 2002 allowed Calum to develop his principal research interest in bronchiolitis and influenza, the two most important causes of Severe Acute Respiratory Infections (SARI) in children and adults.

He was jointly appointed Senior Clinical Lecturer in Child Health at University of Liverpool with tenure and Consultant in Paediatric Respiratory Medicine at Alder Hey Children's Hospital in 2006. His personal chair in Child Health and Outbreak Medicine was awarded in December 2017.

He is Chief Investigator for BESS, FLU-CATs, WHO ISARIC Clinical Characterisation Protocol UK, and Convalescent Plasma for Ebola Virus Disease in Sierra Leone "Ebola_CP" and BESS.

BESS - the Bronchiolitis Endotracheal Surfactant Study in a multinational randomised controlled trial of Endotracheal Surfactant administered to infants with life-threatening Bronchiolitis funded by the NIHR EME programme.

He is co-investigator on ARCHIE (2014-) and Emergency Evaluation of Convalescent Plasma for Ebola Viral Disease (EVD) in Guinea "Ebola-Tx" (2014-17). Calum was a co-investigator on the FLU-CIN and MOSAIC studies that characterized in near real-time the clinical and immunological response to Influenza A/H1N1pdm2009 infection during the pandemic.

Calum is the Senior Clinical Editor of the journal Influenza and Other Respiratory Viruses. He is a member of NERVTAG is an expert committee of the Department of Health (DH), that advises the Chief Medical Officer (CMO) and, through the CMO, ministers, DH and other Government departments on New and Emerging Respiratory Viral Threats.

Calum provides a tertiary paediatric respiratory outpatient clinic and runs the regional paediatric bronchoscopy service with Professor Kevin Southern and colleagues at Alder Hey Children’s Hospital.

Calum volunteered at the London 2012 Olympic Games where he led the shooting field of play medical team at the Royal Artillery Barracks. He is a volunteer medical officer to the Cheshire, Merseyside and North West Counties Amateur Boxing Association.

Academic Secretary: Mrs Moira Saphier +44 (0) 151 252 5250
Clinical Secretary: Mrs Renate Manning +44 (0) 151 293 3641

Personal Distinctions

  • Queen's Ebola Medal for Service in West Africa (Health Research Activities) (Her Majesty's Government 2016)
  • Letter from Prime Minister (Olympic Games Health Threat Response) (Prime Minister HMG UK 2012)
  • Letter from Chief Medical Officer (Pandemic Influenza Research Response) (Chief Medical Officer 2011)
  • Letter from Secretary of State (Pandemic Influenza Research Response) (Secretary of State for Health 2009)
  • Letter to VC from Director General NHS R&D and Chair of SAGE (Department of Health, HMG UK 2009)
  • American Thoracic Society International Trainee Award (Prize, American Thoracic Society 2006)
  • Host and lead organiser for the Inaugral National Clinician Scientist Meeting, Liverpool 2005 (Invitation to Speak, Academy of Medical Sciences & NCS Stakeholders UK 2005)
  • Vice Chancellor's Future Research Leaders Award (Competitive Fellowship, University of Liverpool 2004)
  • National Clinician Scientitst Award (Competitive Fellowship, Department of Health HMG UK 2002)

Administrative Roles

  • Deputy Director of Integrated Clinical Academic Training, University of Liverpool
  • Chair of Institute of Translational Medicine Regulatory Affairs Committee
  • Member of Faculty Regulatory Affairs Committee, University of Liverpool
  • Regional Academic Advisor, Royal College of Paediatrics and Child Health

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