Photo of Prof Christian Hedrich

Prof Christian Hedrich MD, PhD

Professor of Child Health Women's and Children's Health

About

Personal Statement

Professor Christian Hedrich is a Paediatric Rheumatologist with special interest in molecular mechanisms of cytokine dysregulation in autoimmune/inflammatory disease, their potential applicability as disease biomarkers, and the resolution of pathological inflammatory responses by individualized and target-directed therapeutic approaches. In August 2017, he was appointed Professor of Child Health at the University of Liverpool, Faculty of Health and Life Sciences, Department of Women's and Children's Health. Previously, he served as Head of Paediatric Rheumatology and Immunology at the Faculty of Medicine Carl Gustav Carus, TU Dresden, Germany.

Christian Hedrich completed his medical training and doctoral degree (Dr. med.) at the University of Ulm Medical School, Ulm, Germany. He undertook a residency program in General Paediatrics, followed by a sub-specialty fellowship in Paediatric Rheumatology in the Department of Paediatrics, Faculty of Medicine Carl Gustav Carus, TU Dresden, Dresden, Germany. He received his scientific training in Germany (University of Ulm, and TU Dresden) and the United States, where he completed a research fellowship at the Johns Hopkins School of Public Health in Baltimore, MD, USA, followed by a research fellowship and appointment as Instructor in Medicine at Beth Israel Deaconess Medical Center, Harvard University, Boston, MA, USA. In 2014, Christian Hedrich received his teaching license (Habilitation; Dr. med. habil.) from the Faculty of Medicine Carl Gustav Carus, TU Dresden based on his his thesis entitled "Molecular mechanisms of cytokine dysregulation and their contribution to the pathophysiology of autoimmune/inflammatory disorders".

Christian Hedrich's core research interests are molecular mechanisms of cytokine regulation and their effects on disease expression in the spectrum from autoinflammation to autoimmunity. Special foci include the autoinflammatory bone disorder chronic nonbacterial osteomyelitis (CNO), the mixed-pattern disease psoriasis, and the prototypical autoimmune disorder systemic lupus erythematosus (SLE). Christian Hedrich is actively involved with consensus treatment plan initiatives of the North American CARRA group (CNO) and treat to target (T2T) initiatives of the German Society of Pediatric Rheumatology (GKJR) (SLE, systemic JIA, CNO). Both initiatives aim at translating knowledge from small patient cohorts, daily clinical experience, and laboratory studies into routine patient care, and back to the laboratory bench.

Prizes or Honours

  • Abstract Award for “Serum biomarkers for the diagnosis and monitoring of CRMO” (Childhood Arthritis and Rheumatism Research Alliance (CARRA), 2016)
  • Award for best abstract presentation (oral) (German Pediatric Immunology Society (API), 2015)
  • Award for best abstract presentation (oral) in session “New aspects in pathophysiology of auto-inflammation” (International Society of Systemic Autoinflammatory Syndromes (ISSAID), 2015)
  • Young Investigator Award (American Association of Immunologists (AAI), 2012)
  • Young Investigator Award (German Pediatric Rheumatology Society (GKJR), 2010)
  • Scholarship to the CIS School in Systemic Autoimmune Diseases (Clinical Immunology Society (CIS), 2008)

Funded Fellowships

  • Postgraduate Research Award (Novartis Foundation for Therapeutic Research, 2013)
  • Grant for a Postdoctoral Research Fellowship at the W. Harry Feinstone Department of Molecular Microbiology and Immunology, The Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA (German Research Foundation (DFG), 2007)