2024
Maldonado, H., Savage, B. D., Barker, H. R., May, U., Vähätupa, M., Badiani, R. K., . . . Järvinen, T. A. H. (2024). Author Correction: Systemically administered wound-homing peptide accelerates wound healing by modulating syndecan-4 function.. Nature communications, 15(1), 234. doi:10.1038/s41467-023-44574-4DOI: 10.1038/s41467-023-44574-4
2023
Newman, D., Young, L. E., Waring, T., Brown, L., Wolanska, K. I., MacDonald, E., . . . Zech, T. (2023). 3D matrix adhesion feedback controls nuclear force coupling to drive invasive cell migration.. Cell reports, 42(12), 113554. doi:10.1016/j.celrep.2023.113554DOI: 10.1016/j.celrep.2023.113554
Maldonado, H., Savage, B., Barker, H., May, U., Vähätupa, M., Badiani, R., . . . Järvinen, T. (2023). [Tissue injury targeting peptide accelerates wound healing] Kudosvammaan hakeutuva peptidi kiihdyttää vamman paranemista. Duodecim Medical Journal, 139. Retrieved from https://www.duodecimlehti.fi/xmedia/duo/duo18037.pdf
Maldonado, H., Savage, B. D., Barker, H. R., May, U., Vähätupa, M., Badiani, R. K., . . . Järvinen*, T. A. H. (2023). Systemically administered wound-homing peptide accelerates wound healing by modulating syndecan-4 function. Nature Communications.
A trafficking regulatory subnetwork governs αVβ6 Integrin-HER2 crosstalk to control breast cancer invasion and drug resistance (Preprint)
DOI: 10.21203/rs.3.rs-3318304/v2
2022
Pang, Y., Maxwell, E., Sindrewicz-Goral, P., Shapanis, A., Li, S., Morgan, M., & Yu, L. -G. (n.d.). Galectin-3 Is a Natural Binding Ligand of MCAM (CD146, MUC18) in Melanoma Cells and Their Interaction Promotes Melanoma Progression. Biomolecules, 12(10), 1451. doi:10.3390/biom12101451DOI: 10.3390/biom12101451
2021
2019
Thomas, J. R., Paul, N. R., & Morgan, M. R. (2019). Adhesion and growth factor receptor crosstalk mechanisms controlling cell migration. MECHANISMS OF CELL MIGRATION, 63(5), 553-567. doi:10.1042/EBC20190025DOI: 10.1042/EBC20190025
Hill, C. J., Fleming, J. R., Mousavinejad, M., Nicholson, R., Tzokov, S. B., Bullough, P. A., . . . Murray, P. (2019). Self-Assembling Proteins as High-Performance Substrates for Embryonic Stem Cell Self-Renewal. Advanced Materials, 31(17). doi:10.1002/adma.201807521DOI: 10.1002/adma.201807521
2018
Paul, N., Thomas, J., Maldonado, H., Wolanska, K., Koper, E., Humphries, J., . . . Morgan, M. (2018). Eps8 is a convergence point integrating EGFR and integrin trafficking and crosstalk. doi:10.1101/405043DOI: 10.1101/405043
Thomas, J., Moore, K., Sproat, C., Maldonado-Lorca, H., Mo, S., Haider, S., . . . Morgan, M. (2018). Integrin αVβ6-EGFR crosstalk regulates bidirectional force transmission and controls breast cancer invasion. doi:10.1101/407908DOI: 10.1101/407908
2017
Borland, S. J., Morris, T. G., Borland, S. C., Morgan, M. R., Francis, S. E., Merry, C. L. R., & Canfield, A. E. (2017). Regulation of vascular smooth muscle cell calcification by syndecan-4/FGF-2/PKCα signaling and cross-talk with TGFβ. Cardiovascular Research, 113(13), 1639-1652. doi:10.1093/cvr/cvx178DOI: 10.1093/cvr/cvx178
Tod, J., Hanley, C. J., Morgan, M. R., Rucka, M., Mellows, T., Lopez, M. -A., . . . Thomas, G. J. (2017). Pro-migratory and TGF-β-activating functions of αvβ6 integrin in pancreatic cancer are differentially regulated via an Eps8-dependent GTPase switch. The Journal of Pathology, 243(1), 37-50. doi:10.1002/path.4923DOI: 10.1002/path.4923
2016
Mana, G., Clapero, F., Panieri, E., Panero, V., Böttcher, R. T., Tseng, H. -Y., . . . Valdembri, V. (2016). PPFIA1 drives active α5β1 integrin recycling and controls fibronectin fibrillogenesis and vascular morphogenesis. Nature Communications, 7. doi:10.1038/ncomms13546DOI: 10.1038/ncomms13546
2015
Emerging properties of adhesion complexes: what are they and what do they do? (Journal article)
Humphries, J. D., Paul, N. R., Humphries, M. J., & Morgan, M. R. (2015). Emerging properties of adhesion complexes: what are they and what do they do?. TRENDS IN CELL BIOLOGY, 25(7), 388-397. doi:10.1016/j.tcb.2015.02.008DOI: 10.1016/j.tcb.2015.02.008
Fibronectin remodelling: cell-mediated regulation of the microenvironment (Journal article)
Wolanska, K. I., & Morgan, M. R. (2015). Fibronectin remodelling: cell-mediated regulation of the microenvironment. BIOCHEMICAL SOCIETY TRANSACTIONS, 43, 122-128. doi:10.1042/BST20140313DOI: 10.1042/BST20140313
2013
Rac1 is deactivated at integrin activation sites through an IQGAP1-filamin-A-RacGAP1 pathway (Journal article)
Jacquemet, G., Morgan, M. R., Byron, A., Humphries, J. D., Choi, C. K., Chen, C. S., . . . Humphries, M. J. (2013). Rac1 is deactivated at integrin activation sites through an IQGAP1-filamin-A-RacGAP1 pathway. JOURNAL OF CELL SCIENCE, 126(18), 4121-4135. doi:10.1242/jcs.121988DOI: 10.1242/jcs.121988
Morgan, M. R., Hamidi, H., Bass, M. D., Warwood, S., Ballestrem, C., & Humphries, M. J. (2013). Syndecan-4 Phosphorylation Is a Control Point for Integrin Recycling. DEVELOPMENTAL CELL, 24(5), 472-485. doi:10.1016/j.devcel.2013.01.027DOI: 10.1016/j.devcel.2013.01.027
2012
A Syndecan-4 Hair Trigger Initiates Wound Healing through Caveolin- and RhoG-Regulated Integrin Endocytosis (vol 21, pg 681, 2011) (Journal article)
Bass, M. D., Williamson, R. C., Nunan, R. D., Humphries, J. D., Byron, A., Morgan, M. R., . . . Humphries, M. J. (2012). A Syndecan-4 Hair Trigger Initiates Wound Healing through Caveolin- and RhoG-Regulated Integrin Endocytosis (vol 21, pg 681, 2011). DEVELOPMENTAL CELL, 23(5), 1081-1082. doi:10.1016/j.devcel.2012.10.021DOI: 10.1016/j.devcel.2012.10.021
2011
A Syndecan-4 Hair Trigger Initiates Wound Healing through Caveolin- and RhoG-Regulated Integrin Endocytosis (Journal article)
Bass, M. D., Williamson, R. C., Nunan, R. D., Humphries, J. D., Byron, A., Morgan, M. R., . . . Humphries, M. J. (2011). A Syndecan-4 Hair Trigger Initiates Wound Healing through Caveolin- and RhoG-Regulated Integrin Endocytosis. DEVELOPMENTAL CELL, 21(4), 681-693. doi:10.1016/j.devcel.2011.08.007DOI: 10.1016/j.devcel.2011.08.007
Psoriasin (S100A7) associates with integrin β6 subunit and is required for αvβ6-dependent carcinoma cell invasion (Journal article)
Morgan, M. R., Jazayeri, M., Ramsay, A. G., Thomas, G. J., Boulanger, M. J., Hart, I. R., & Marshall, J. F. (2011). Psoriasin (S100A7) associates with integrin β6 subunit and is required for αvβ6-dependent carcinoma cell invasion. ONCOGENE, 30(12), 1422-1435. doi:10.1038/onc.2010.535DOI: 10.1038/onc.2010.535
2010
Adhesion signalling complexes (Journal article)
Byron, A., Morgan, M. R., & Humphries, M. J. (2010). Adhesion signalling complexes. CURRENT BIOLOGY, 20(24), R1063-R1067. doi:10.1016/j.cub.2010.10.059DOI: 10.1016/j.cub.2010.10.059
2009
Giving off Mixed Signals-Distinct Functions of α<sub>5</sub>β<sub>1</sub> and α<sub>V</sub>β<sub>3</sub> Integrins in Regulating Cell Behaviour (Journal article)
Morgan, M. R., Byron, A., Humphries, M. J., & Bass, M. D. (2009). Giving off Mixed Signals-Distinct Functions of α<sub>5</sub>β<sub>1</sub> and α<sub>V</sub>β<sub>3</sub> Integrins in Regulating Cell Behaviour. IUBMB LIFE, 61(7), 731-738. doi:10.1002/iub.200DOI: 10.1002/iub.200
Syndecans Shed Their Reputation as Inert Molecules (Journal article)
Bass, M. D., Morgan, M. R., & Humphries, M. J. (2009). Syndecans Shed Their Reputation as Inert Molecules. SCIENCE SIGNALING, 2(64). doi:10.1126/scisignal.264pe18DOI: 10.1126/scisignal.264pe18
Therapeutic Ultrasound Bypasses Canonical Syndecan-4 Signaling to Activate Rac1 (Journal article)
Mahoney, C. M., Morgan, M. R., Harrison, A., Humphries, M. J., & Bass, M. D. (2009). Therapeutic Ultrasound Bypasses Canonical Syndecan-4 Signaling to Activate Rac1. JOURNAL OF BIOLOGICAL CHEMISTRY, 284(13), 8889-8900. doi:10.1074/jbc.M804281200DOI: 10.1074/jbc.M804281200
2008
p190RhoGAP is the convergence point of adhesion signals from α<sub>5</sub>β<sub>1</sub> integrin and syndecan-4 (Journal article)
Bass, M. D., Morgan, M. R., Roach, K. A., Settleman, J., Goryachev, A. B., & Humphries, M. J. (2008). p190RhoGAP is the convergence point of adhesion signals from α<sub>5</sub>β<sub>1</sub> integrin and syndecan-4. JOURNAL OF CELL BIOLOGY, 181(6), 1013-1026. doi:10.1083/jcb.200711129DOI: 10.1083/jcb.200711129
2007
Morgan, M. R., Humphries, M. J., & Bass, M. D. (2007). Synergistic control of cell adhesion by integrins and syndecans. NATURE REVIEWS MOLECULAR CELL BIOLOGY, 8(12), 957-969. doi:10.1038/nrm2289DOI: 10.1038/nrm2289
Sndecan-4-dependent Rac1 regulation determines directional migration in response to the extracellular matrix (Journal article)
Bass, M. D., Roach, K. A., Morgan, M. R., Mostafavi-Pour, Z., Schoen, T., Muramatsu, T., . . . Humphries, M. J. (2007). Sndecan-4-dependent Rac1 regulation determines directional migration in response to the extracellular matrix. JOURNAL OF CELL BIOLOGY, 177(3), 527-538. doi:10.1083/jcb.200610076DOI: 10.1083/jcb.200610076
Integrins and syndecan-4 make distinct, but critical, contributions to adhesion contact formation (Journal article)
Bass, M. D., Morgan, M. R., & Humphries, M. J. (2007). Integrins and syndecan-4 make distinct, but critical, contributions to adhesion contact formation. SOFT MATTER, 3(3), 372-376. doi:10.1039/b614610dDOI: 10.1039/b614610d
2005
Integrin-syndecan cooperation governs the assembly of signalling complexes during cell spreading. (Conference Paper)
Humphries, M. J., Mostafavi-Pour, Z., Morgan, M. R., Deakin, N. O., Messent, A. J., & Bass, M. D. (2005). Integrin-syndecan cooperation governs the assembly of signalling complexes during cell spreading.. In Novartis Foundation symposium Vol. 269 (pp. 178-230).
2004
Morgan, M. R., Thomas, G. J., Russell, A., Hart, I. R., & Marshall, J. F. (2004). The integrin cytoplasmic-tail motif EKQKVDLSTDC is sufficient to promote tumor cell invasion mediated by matrix metalloproteinase (MMP)-2 or MMP-9. JOURNAL OF BIOLOGICAL CHEMISTRY, 279(25), 26533-26539. doi:10.1074/jbc.M401736200DOI: 10.1074/jbc.M401736200
Modulation of the urokinase-type plasminogen activator receptor by the β6 integrin subunit (Journal article)
Dalvi, N., Thomas, G. J., Marshall, J. F., Morgan, M., Bass, R., Ellis, V., . . . Whawell, S. A. (2004). Modulation of the urokinase-type plasminogen activator receptor by the β6 integrin subunit. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 317(1), 92-99. doi:10.1016/j.bbrc.2004.02.178DOI: 10.1016/j.bbrc.2004.02.178
Reduction of TSG101 protein has a negative impact on tumor cell growth (Journal article)
Zhu, G., Gilchrist, R., Borley, N., Chng, H. W., Morgan, M., Marshall, J. F., . . . Hart, I. R. (2004). Reduction of TSG101 protein has a negative impact on tumor cell growth. INTERNATIONAL JOURNAL OF CANCER, 109(4), 541-547. doi:10.1002/ijc.20014DOI: 10.1002/ijc.20014
Role of the β6 integrin cytoplasmic domain in carcinoma cell invasion (Thesis / Dissertation)
Morgan, M. (2004). Role of the β6 integrin cytoplasmic domain in carcinoma cell invasion. (PhD Thesis, University of London (Kings College)).
2002
Patent: Biologically Active Molecules (Journal article)
Morgan, M., Marshall, J. F., & Williams, G. (2002). Patent: Biologically Active Molecules.
