2024
Neuroendocrine neoplasms: Consensus on a patient care pathway. (Journal article)
Hooper, J., Jervis, N., Morgan, L., Beckett, V., Hand, P., Higgs, K., . . . Ellis, C. B. (2024). Neuroendocrine neoplasms: Consensus on a patient care pathway.. Journal of neuroendocrinology, 36(4), e13380. doi:10.1111/jne.13380DOI: 10.1111/jne.13380
PREF-NET: A patient preference and experience study of lanreotide autogel (LAN) administered in the home versus hospital setting among patients with gastroenteropancreatic neuroendocrine tumors (GEP-NETs) in the UK (Conference Paper)
Khan, M., Davies, L., Back, M., Shah, T., Pritchard, D., Cook, K., . . . Higgs, K. (2023). PREF-NET: A patient preference and experience study of lanreotide autogel (LAN) administered in the home versus hospital setting among patients with gastroenteropancreatic neuroendocrine tumors (GEP-NETs) in the UK. In JOURNAL OF NEUROENDOCRINOLOGY Vol. 35 (pp. 225). Retrieved from https://www.webofscience.com/
Khan, M. S., Cook, K., Weickert, M. O., Davies, L., Pritchard, D. M., Day, M., . . . Higgs, K. (2024). PREF-NET: a patient preference and experience study of lanreotide autogel administered in the home versus hospital setting among patients with gastroenteropancreatic neuroendocrine tumours in the UK.. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 32(3), 199. doi:10.1007/s00520-024-08377-7DOI: 10.1007/s00520-024-08377-7
2023
Gall, L., Duckworth, C., Jardi, F., Lammens, L., Parker, A., Bianco, A., . . . Pin, C. (2023). Homeostasis, injury, and recovery dynamics at multiple scales in a self-organizing mouse intestinal crypt.. eLife, 12, e85478. doi:10.7554/elife.85478DOI: 10.7554/elife.85478
Letter to the editor: <i>Helicobacter pylori</i> eradication - the proof is not in the symptoms (Journal article)
Bornschein, J., Pritchard, D. M., & Malfertheiner, P. (2022). Letter to the editor: <i>Helicobacter pylori</i> eradication - the proof is not in the symptoms. GUT. doi:10.1136/gutjnl-2022-329057DOI: 10.1136/gutjnl-2022-329057
Gall, L., Jardi, F., Lammens, L., Piñero, J., Souza, T. M., Rodrigues, D., . . . Pin, C. (2023). A dynamic model of the intestinal epithelium integrates multiple sources of preclinical data and enables clinical translation of drug-induced toxicity.. CPT: pharmacometrics & systems pharmacology. doi:10.1002/psp4.13029DOI: 10.1002/psp4.13029
Panzuto, F., Ramage, J., Pritchard, D. M., van Velthuysen, M. -L. F., Schrader, J., Begum, N., . . . O'Toole, D. (2023). European Neuroendocrine Tumor Society (ENETS) 2023 guidance paper for gastroduodenal neuroendocrine tumours (NETs) G1-G3. JOURNAL OF NEUROENDOCRINOLOGY. doi:10.1111/jne.13306DOI: 10.1111/jne.13306
Multiple and diverse consequences of inhibiting gastric acid secretion: remembering the bicentenary of William Prout's discovery (Journal article)
Pritchard, D. M., & Logan, R. (2023). Multiple and diverse consequences of inhibiting gastric acid secretion: remembering the bicentenary of William Prout's discovery. GUT. doi:10.1136/gutjnl-2023-330133DOI: 10.1136/gutjnl-2023-330133
Li, S., Pritchard, D. M., & Yu, L. -G. (2023). Galectin-3 promotes secretion of proteases that decrease epithelium integrity in human colon cancer cells. CELL DEATH & DISEASE, 14(4). doi:10.1038/s41419-023-05789-xDOI: 10.1038/s41419-023-05789-x
The Role of Contact X-Ray Brachytherapy in Early Rectal Cancer- Who, when and How? (Journal article)
Myint, A. S., Dhadda, A., Stewart, A., Mills, J., Sripadam, R., Rao, C., . . . Gerard, J. P. (2023). The Role of Contact X-Ray Brachytherapy in Early Rectal Cancer- Who, when and How?. CLINICAL ONCOLOGY, 35(2), 87-96. doi:10.1016/j.clon.2022.10.003DOI: 10.1016/j.clon.2022.10.003
Mouse organoids as an in vitro tool to study the in vivo intestinal response to cytotoxicants (Journal article)
Jardi, F., Kelly, C., Teague, C., Fowler-Williams, H., Sevin, D. C., Rodrigues, D., . . . Pritchard, D. M. (2023). Mouse organoids as an in vitro tool to study the in vivo intestinal response to cytotoxicants. ARCHIVES OF TOXICOLOGY, 97(1), 235-254. doi:10.1007/s00204-022-03374-3DOI: 10.1007/s00204-022-03374-3
2022
Endoscopic surveillance alone is feasible and safe in type I gastric neuroendocrine neoplasms less than 10mm in diameter (Conference Paper)
Exarchou, K., Hu, H., Stephens, N. A., Moore, A. R., Kelly, M., Lamarca, A., . . . Pritchard, D. M. (2022). Endoscopic surveillance alone is feasible and safe in type I gastric neuroendocrine neoplasms less than 10mm in diameter. In BRITISH JOURNAL OF SURGERY Vol. 109. doi:10.1093/bjs/znac404.040DOI: 10.1093/bjs/znac404.040
Karageorgou, M., Hughes, D. M., Myint, A. S., Pritchard, D. M., & Bonnett, L. J. (2022). Clinical prediction models assessing response to radiotherapy for rectal cancer: protocol for a systematic review.. Diagnostic and prognostic research, 6(1), 19. doi:10.1186/s41512-022-00132-yDOI: 10.1186/s41512-022-00132-y
Exarchou, K., Hu, H., Stephens, N. A., Moore, A. R., Kelly, M., Lamarca, A., . . . Pritchard, D. M. (2022). Endoscopic surveillance alone is feasible and safe in type I gastric neuroendocrine neoplasms less than 10 mm in diameter. ENDOCRINE, 78(1), 186-196. doi:10.1007/s12020-022-03143-3DOI: 10.1007/s12020-022-03143-3
Papoutsopoulou, S., Tang, J., Elramli, A. H., Williams, J. M., Gupta, N., Ikuomola, F. I., . . . Pritchard, D. M. (2022). Nfkb2 deficiency and its impact on plasma cells and immunoglobulin expression in murine small intestinal mucosa. American Journal of Physiology: Gastrointestinal and Liver Physiology, 323(4), G306-G317. doi:10.1152/ajpgi.00037.2022DOI: 10.1152/ajpgi.00037.2022
Myint, A. S., Dhadda, A. S., Stewart, A., Mills, J., Sripadam, R., Rao, C., . . . Gerard, J. P. (2022). New hope from OPERA trial for surgically fit rectal cancer patients who wish to have organ preservation.. Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland. doi:10.1111/codi.16286DOI: 10.1111/codi.16286
Li, S., Pritchard, D. M., & Yu, L. -G. (2022). Regulation and Function of Matrix Metalloproteinase-13 in Cancer Progression and Metastasis. CANCERS, 14(13). doi:10.3390/cancers14133263DOI: 10.3390/cancers14133263
Bornschein, J., & Pritchard, D. M. (2022). Myths and misconceptions in the management of <i>Helicobacter pylori</i> infection. FRONTLINE GASTROENTEROLOGY, 13(3), 245-253. doi:10.1136/flgastro-2021-101826DOI: 10.1136/flgastro-2021-101826
Exarchou, K., Stephens, N. A., Moore, A. R., Howes, N. R., & Pritchard, D. M. (2022). New Developments in Gastric Neuroendocrine Neoplasms. Current Oncology Reports. doi:10.1007/s11912-021-01175-yDOI: 10.1007/s11912-021-01175-y
Khan, M. S., & Pritchard, D. M. (n.d.). Neuroendocrine tumours: what gastroenterologists need to know. Frontline Gastroenterology. doi:10.1136/flgastro-2020-101431DOI: 10.1136/flgastro-2020-101431
Pritchard, D. M. (2022). New Mouse Model Suggests That Some Neuroendocrine Tumors May Originate From Neural Crest-Derived Cells.. Cellular and molecular gastroenterology and hepatology, 14(5), 1170-1171. doi:10.1016/j.jcmgh.2022.08.005DOI: 10.1016/j.jcmgh.2022.08.005
2021
Bourgeois, S., Carr, D. F., Musumba, C. O., Penrose, A., Esume, C., Morris, A. P., . . . Pirmohamed, M. (2021). Genome-Wide association between EYA1 and Aspirin-induced peptic ulceration. EBioMedicine, 74, 103728. doi:10.1016/j.ebiom.2021.103728DOI: 10.1016/j.ebiom.2021.103728
Veysey-Smith, R., Moore, A. R., Murugesan, S. V., Tiszlavicz, L., Dockray, G. J., Varro, A., & Pritchard, D. M. (2021). Effects of Proton Pump Inhibitor Therapy, <i>H</i>. <i>pylori</i> Infection and Gastric Preneoplastic Pathology on Fasting Serum Gastrin Concentrations. FRONTIERS IN ENDOCRINOLOGY, 12. doi:10.3389/fendo.2021.741887DOI: 10.3389/fendo.2021.741887
Snook, J., Bhala, N., Beales, I. L. P., Cannings, D., Kightley, C., Logan, R. P., . . . Goddard, A. F. (2021). British Society of Gastroenterology guidelines for the management of iron deficiency anaemia in adults. GUT, 70(11), 2030-2051. doi:10.1136/gutjnl-2021-325210DOI: 10.1136/gutjnl-2021-325210
Exarchou, K., Kamieniarz, L., Tsoli, M., Victor, A., Oleinikov, K., Khan, M. S., . . . Toumpanakis, C. (2021). Is local excision sufficient in selected grade 1 or 2 type III gastric neuroendocrine neoplasms?. ENDOCRINE, 74(2), 421-429. doi:10.1007/s12020-021-02775-1DOI: 10.1007/s12020-021-02775-1
Ali, M., Aziz, S., Ahmad, I., Saadia, A., Zahra, R., May, F. E. B., . . . Rasheed, F. (2021). Gastric metastasis before diagnosis of primary invasive lobular breast carcinoma: a rare case presentation from Pakistan. Women & Health, 1-5. doi:10.1080/03630242.2021.1981516DOI: 10.1080/03630242.2021.1981516
Alabraba, E., Pritchard, D. M., Griffin, R., Diaz-Nieto, R., Banks, M., Cuthbertson, D. J., & Fenwick, S. (2021). Appendiceal goblet cell carcinomas have poor survival despite completion surgery. ENDOCRINE, 73(3), 734-744. doi:10.1007/s12020-021-02727-9DOI: 10.1007/s12020-021-02727-9
Wang, W., Sindrewicz-Goral, P., Chen, C., Duckworth, C. A., Pritchard, D. M., Rhodes, J. M., & Yu, L. -G. (2021). Appearance of peanut agglutinin in the blood circulation after peanut ingestion promotes endothelial secretion of metastasis-promoting cytokines. CARCINOGENESIS, 42(8), 1079-1088. doi:10.1093/carcin/bgab059DOI: 10.1093/carcin/bgab059
Pritchard, D. M., Bornschein, J., Beales, I. L. P., Salhi, H., Beresniak, A., & Malfertheiner, P. (2021). "Test-and-treat" strategy with urea breath test: A cost-effective approach for the management of Helicobacter pylori-related dyspepsia and the prevention of peptic ulcer in the United Kingdom-results of the Hp-Breath initiative. In HELICOBACTER Vol. 25 (pp. 3). Retrieved from http://gateway.webofknowledge.com/
Exarchou, K., Moore, A. R., Smart, H. L., Duckworth, C. A., Howes, N., & Pritchard, D. M. (2021). A "Watch and Wait" Strategy Involving Regular Endoscopic Surveillance Is Safe for Many Patients with Small, Sporadic, Grade 1, Non-Ampullary, Non-Functioning Duodenal Neuroendocrine Tumours. NEUROENDOCRINOLOGY, 111(8), 764-774. doi:10.1159/000511613DOI: 10.1159/000511613
Pritchard, D. M., Bornschein, J., Beales, I., Beresniak, A., Salhi, H., & Malfertheiner, P. (2021). Cost-effectiveness modelling of use of urea breath test for the management of <i>Helicobacter pylori</i>-related dyspepsia and peptic ulcer in the UK. BMJ OPEN GASTROENTEROLOGY, 8(1). doi:10.1136/bmjgast-2021-000685DOI: 10.1136/bmjgast-2021-000685
Mahalhal, A., Frau, A., Burkitt, M. D., Ijaz, U. Z., Lamb, C. A., Mansfield, J. C., . . . Probert, C. S. (2021). Oral Ferric Maltol Does Not Adversely Affect the Intestinal Microbiome of Patients or Mice, but Ferrous Sulphate Does. NUTRIENTS, 13(7). doi:10.3390/nu13072269DOI: 10.3390/nu13072269
Cuthbertson, D. J., Barriuso, J., Lamarca, A., Manoharan, P., Westwood, T., Jaffa, M., . . . Yip, V. S. (2021). The Impact of <SUP>68</SUP>Gallium DOTA PET/CT in Managing Patients With Sporadic and Familial Pancreatic Neuroendocrine Tumours. FRONTIERS IN ENDOCRINOLOGY, 12. doi:10.3389/fendo.2021.654975DOI: 10.3389/fendo.2021.654975
IP1867B suppresses the Insulin-like Growth Factor 1 Receptor (IGF1R) ablating epidermal growth factor receptor inhibitor resistance in adult high grade gliomas (Retraction of Vol 458, Pg 29, 2019) (Journal article)
Mihajluk, K., Simms, C., Reay, M., Madureira, P. A., Howarth, A., Murray, P., . . . Hill, R. (2021). IP1867B suppresses the Insulin-like Growth Factor 1 Receptor (IGF1R) ablating epidermal growth factor receptor inhibitor resistance in adult high grade gliomas (Retraction of Vol 458, Pg 29, 2019). CANCER LETTERS, 507, 39. doi:10.1016/j.canlet.2021.03.008DOI: 10.1016/j.canlet.2021.03.008
Alabraba, E., Pritchard, D. M., Griffin, R., Diaz-Nieto, R., Banks, M., Cuthbertson, D. J., & Fenwick, S. (n.d.). The impact of lymph node metastases and right hemicolectomy on outcomes in appendiceal neuroendocrine tumours (aNETs).. Eur J Surg Oncol. doi:10.1016/j.ejso.2020.09.012DOI: 10.1016/j.ejso.2020.09.012
Mahalhal, A., Burkitt, M. D., Duckworth, C. A., Hold, G. L., Campbell, B. J., Pritchard, D. M., & Probert, C. S. (2021). Long-Term Iron Deficiency and Dietary Iron Excess Exacerbate Acute Dextran Sodium Sulphate-Induced Colitis and Are Associated with Significant Dysbiosis. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 22(7). doi:10.3390/ijms22073646DOI: 10.3390/ijms22073646
Duran, C., Ciucci, S., Palladini, A., Ijaz, U. Z., Zippo, A. G., Sterbini, F. P., . . . Cannistraci, C. V. (2021). Nonlinear machine learning pattern recognition and bacteria-metabolite multilayer network analysis of perturbed gastric microbiome. NATURE COMMUNICATIONS, 12(1). doi:10.1038/s41467-021-22135-xDOI: 10.1038/s41467-021-22135-x
IRINOTECAN INDUCES A RAPID INCREASE IN ENTEROID PERMEABILITY (Conference Paper)
Turnbull, J. L., Lynch, S., Pritchard, D. M., Goldring, C. E. P., & Duckworth, C. A. (2021). IRINOTECAN INDUCES A RAPID INCREASE IN ENTEROID PERMEABILITY. In GUT Vol. 70 (pp. A177-A178). doi:10.1136/gutjnl-2020-bsgcampus.337DOI: 10.1136/gutjnl-2020-bsgcampus.337
2020
Butler, O. L., Mekhael, M. M., Ahmed, A., Cuthbertson, D. J., & Pritchard, D. M. (n.d.). Frequency and Causes of False-Positive Elevated Plasma Concentrations of Fasting Gut Hormones in a Specialist Neuroendocrine Tumor Center. Frontiers in Endocrinology, 11. doi:10.3389/fendo.2020.606264DOI: 10.3389/fendo.2020.606264
Buchanan-Hughes, A., Pashley, A., Feuilly, M., Marteau, F., Pritchard, D. M., & Singh, S. (2020). Carcinoid Heart Disease: Prognostic Value of 5-Hydroxyindoleacetic Acid Levels and Impact on Survival: A Systematic Literature Review. NEUROENDOCRINOLOGY, 111(1-2), 1-15. doi:10.1159/000506744DOI: 10.1159/000506744
Using systems medicine to identify a therapeutic agent with potential for repurposing in inflammatory bowel disease (Journal article)
Lloyd, K., Papoutsopoulou, S., Smith, E., Stegmaier, P., Bergey, F., Morris, L., . . . Burkitt, M. D. (2020). Using systems medicine to identify a therapeutic agent with potential for repurposing in inflammatory bowel disease. DISEASE MODELS & MECHANISMS, 13(11). doi:10.1242/dmm.044040DOI: 10.1242/dmm.044040
Queiroz, C. J. S., Song, F., Reed, K. R., Al-Khafaji, N., Clarke, A. R., Vimalachandran, D., . . . Jenkins, J. R. (2020). NAP1L1: A Novel Human Colorectal Cancer Biomarker Derived From Animal Models of<i>Apc</i>Inactivation. FRONTIERS IN ONCOLOGY, 10. doi:10.3389/fonc.2020.01565DOI: 10.3389/fonc.2020.01565
Fust, K., Maschio, M., Kohli, M., Singh, S., Pritchard, D. M., Marteau, F., . . . Feuilly, M. (2020). A Budget Impact Model of the Addition of Telotristat Ethyl Treatment to the Standard of Care in Patients with Uncontrolled Carcinoid Syndrome. In PHARMACOECONOMICS Vol. 38 (pp. 607-618). doi:10.1007/s40273-020-00896-5DOI: 10.1007/s40273-020-00896-5
Exarchou, K., Howes, N., & Pritchard, D. M. (2020). Systematic review: management of localised low-grade upper gastrointestinal neuroendocrine tumours. ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 51(12), 1247-1267. doi:10.1111/apt.15765DOI: 10.1111/apt.15765
Machine learning pattern recognition and differential network analysis of gastric microbiome in the presence of proton pump inhibitor treatment or <i>Helicobacter pylori</i> infection (Preprint)
DOI: 10.1101/2020.03.24.005587
Hu, H., Zhang, Q., Chen, G., Pritchard, D. M., & Zhang, S. (2020). Risk factors and clinical correlates of neoplastic transformation in gastric hyperplastic polyps in Chinese patients. SCIENTIFIC REPORTS, 10(1). doi:10.1038/s41598-020-58900-zDOI: 10.1038/s41598-020-58900-z
IP1867B suppresses the insulin-like growth factor 1 receptor (IGF1R) ablating epidermal growth factor receptor inhibitor resistance in adult high grade gliomas (vol 458C, pg 29, 2019) (Journal article)
Mihajluk, K., Simms, C., Reay, M., Madureira, P. A., Howarth, A., Murray, P., . . . Hill, R. (2020). IP1867B suppresses the insulin-like growth factor 1 receptor (IGF1R) ablating epidermal growth factor receptor inhibitor resistance in adult high grade gliomas (vol 458C, pg 29, 2019). CANCER LETTERS, 469, 524-525. doi:10.1016/j.canlet.2019.10.002DOI: 10.1016/j.canlet.2019.10.002
Lloyd, K. A., Parsons, B. N., Burkitt, M. D., Moore, A. R., Papoutsopoulou, S., Boyce, M., . . . Pritchard, D. M. (2020). Netazepide Inhibits Expression of Pappalysin 2 in Type 1 Gastric Neuroendocrine Tumors. CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY, 10(1), 113-132. doi:10.1016/j.jcmgh.2020.01.010DOI: 10.1016/j.jcmgh.2020.01.010
Type III Gastric Neuroendocrine Neoplasms: Is Local Excision Sufficient in Selected Cases? (Conference Paper)
Exarchou, K., Kameniarz, L., Tsoli, M., Victor, A., Oleinikov, K., Khan, M., . . . Toumpanakis, C. (2020). Type III Gastric Neuroendocrine Neoplasms: Is Local Excision Sufficient in Selected Cases?. In NEUROENDOCRINOLOGY Vol. 110 (pp. 283). Retrieved from https://www.webofscience.com/
2019
Evans, J. P., Winiarski, B. K., Sutton, P. A., Ressel, L., Duckworth, C. A., Pritchard, D. M., . . . Kitteringham, N. R. (2019). Development of an orthotopic syngeneic murine model of colorectal cancer for use in translational research. LABORATORY ANIMALS, 53(6), 598-609. doi:10.1177/0023677219826165DOI: 10.1177/0023677219826165
Jones, L. G., Vaida, A., Thompson, L. M., Ikuomola, F. I., Caamaño, J. H., Burkitt, M. D., . . . Duckworth, C. A. (2019). NF-κB2 signalling in enteroids modulates enterocyte responses to secreted factors from bone marrow-derived dendritic cells. Cell Death and Disease, 10. doi:10.1038/s41419-019-2129-5DOI: 10.1038/s41419-019-2129-5
Frequency and causes of elevated fasting plasma concentrations of a panel of gut hormones in routine clinical practice (Journal article)
Butler, O., Mekhael, M., Ahmed, A., & Pritchard, D. M. (n.d.). Frequency and causes of elevated fasting plasma concentrations of a panel of gut hormones in routine clinical practice. Endocrine Abstracts. doi:10.1530/endoabs.68.p18DOI: 10.1530/endoabs.68.p18
Type III gastric neuroendocrine neoplasms: moving towards less-extensive resections in selected cases? (Journal article)
Exarchou, K., Kameniarz, L., Victor, A., Khan, M., Srirajaskanthan, R., Mandair, D., . . . Toumpanakis, C. (n.d.). Type III gastric neuroendocrine neoplasms: moving towards less-extensive resections in selected cases?. Endocrine Abstracts. doi:10.1530/endoabs.68.p10DOI: 10.1530/endoabs.68.p10
A novel FTIR analysis method for rapid high-confidence discrimination of
esophageal cancer (Journal article)
Martin, D. S., Barrett, S., Weightman, P., & Smith, C. (2019). A novel FTIR analysis method for rapid high-confidence discrimination ofesophageal cancer. Infrared Physics and Technology, 102. doi:10.1016/j.infrared.2019.103007DOI: 10.1016/j.infrared.2019.103007
Papoutsopoulou, S., Burkitt, M. D., Bergey, F., England, H., Hough, R., Schmidt, L., . . . Probert, C. S. (2019). Macrophage-Specific NF-κB Activation Dynamics Can Segregate Inflammatory Bowel Disease Patients. FRONTIERS IN IMMUNOLOGY, 10. doi:10.3389/fimmu.2019.02168DOI: 10.3389/fimmu.2019.02168
Banks, M., Graham, D., Jansen, M., Gotoda, T., Coda, S., di Pietro, M., . . . Dinis-Ribeiro, M. (2019). British Society of Gastroenterology guidelines on the diagnosis and management of patients at risk of gastric adenocarcinoma. GUT, 68(9), 1545-1575. doi:10.1136/gutjnl-2018-318126DOI: 10.1136/gutjnl-2018-318126
Duckworth, C. A., Pritchard, D. M., Mihailuk, K., Simms, C., Reay, M., Madureira, P., . . . Hill, R. (2019). IP1867B suppresses the insulin-like growth factor 1 receptor (IGF1R) ablating epidermal growth factor receptor inhibitor resistance in adult high grade gliomas. Cancer Letters. doi:10.1016/j.canlet.2019.05.028DOI: 10.1016/j.canlet.2019.05.028
Tawfik, A., Knight, P., Duckworth, C. A., Pritchard, D. M., Rhodes, J. M., & Campbell, B. J. (2019). Replication of Crohn's Disease Mucosal E. coli Isolates inside Macrophages Correlates with Resistance to Superoxide and Is Dependent on Macrophage NF-kappa B Activation. PATHOGENS, 8(2). doi:10.3390/pathogens8020074DOI: 10.3390/pathogens8020074
FERRIC MALTOL, UNLIKE FERROUS SULPHATE, DOES NOT ADVERSELY AFFECT THE INTESTINAL MICROBIOME (Conference Paper)
Mahalhal, A., Mansfield, J., Sampson, M., Lewis, S., Lamb, C., Frau, A., . . . Probert, C. (2019). FERRIC MALTOL, UNLIKE FERROUS SULPHATE, DOES NOT ADVERSELY AFFECT THE INTESTINAL MICROBIOME. In GUT Vol. 68 (pp. A84). doi:10.1136/gutjnl-2019-BSGAbstracts.161DOI: 10.1136/gutjnl-2019-BSGAbstracts.161
RISK FACTORS AND CLINICAL CORRELATES OF NEOPLASTIC TRANSFORMATION IN GASTRIC HYPERPLASTIC POLYPSIN CHINESE PATIENTS (Conference Paper)
Hu, H., Zhang, Q., Chen, G., Pritchard, D. M., & Zhang, S. (2019). RISK FACTORS AND CLINICAL CORRELATES OF NEOPLASTIC TRANSFORMATION IN GASTRIC HYPERPLASTIC POLYPSIN CHINESE PATIENTS. In GUT Vol. 68 (pp. A102). doi:10.1136/gutjnl-2019-IDDFabstracts.193DOI: 10.1136/gutjnl-2019-IDDFabstracts.193
Dodd, S., Varro, A., Pritchard, D. M., & Dockray, G. J. (2019). Recharacterization data for a geriatric gastrin polycolonal antibody. DATA IN BRIEF, 24. doi:10.1016/j.dib.2019.103886DOI: 10.1016/j.dib.2019.103886
Burkitt, M. D., Williams, J. M., Townsend, T., Hough, R., Duckworth, C. A., & Pritchard, D. M. (2019). Mice lacking NF-κB1 exhibit marked DNA damage responses and more severe gastric pathology in response to intraperitoneal tamoxifen administration (vol 8, e2939, 2017). CELL DEATH & DISEASE, 10. doi:10.1038/s41419-019-1534-0DOI: 10.1038/s41419-019-1534-0
Long-term iron deficiency and iron supplementation exacerbate acute DSS-induced colitis and are associated with significant dysbiosis (Journal article)
Mahalhal, A., Burkitt, M., Duckworth, C., Hold, G., Campbell, B., Pritchard, M., & Probert, C. (2019). Long-term iron deficiency and iron supplementation exacerbate acute DSS-induced colitis and are associated with significant dysbiosis. doi:10.1101/585174DOI: 10.1101/585174
Potential role of fecal volatile organic compounds as biomarkers of chemically induced intestinal inflammation in mice (Journal article)
Reade, S., Williams, J. M., Aggio, R., Duckworth, C. A., Mahalhal, A., Hough, R., . . . Probert, C. S. (2019). Potential role of fecal volatile organic compounds as biomarkers of chemically induced intestinal inflammation in mice. FASEB JOURNAL, 33(3), 3129-3136. doi:10.1096/fj.201800076RRDOI: 10.1096/fj.201800076RR
Smith, F. M., Pritchard, D. M., Wong, H., Whitmarsh, K., Hershman, M. J., & Sun Myint, A. (2019). A cohort study of local excision followed by adjuvant therapy incorporating a contact x- ray brachytherapy boost instead of radical resection in 180 patients with rectal cancer.. Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland. doi:10.1111/codi.14584DOI: 10.1111/codi.14584
Papoutsopoulou, S., Burkitt, M., Bergey, F., England, H., Hough, R., Schmidt, L., . . . Probert, C. (2019). Macrophage-specific NF-κB activation dynamics can segregate inflammatory bowel disease patients. doi:10.1101/535096DOI: 10.1101/535096
Evans, J. P., Winiarski, B. K., Sutton, P. A., Jones, R. P., Ressel, L., Duckworth, C. A., . . . Kitteringham, N. R. (2019). Correction: The Nrf2 inhibitor brusatol is a potent antitumour agent in an orthotopic mouse model of colorectal cancer.. Oncotarget, 10(6), 685. doi:10.18632/oncotarget.26625DOI: 10.18632/oncotarget.26625
Using systems medicine to identify a therapeutic agent with potential for repurposing in Inflammatory Bowel Disease (Preprint)
DOI: 10.1101/513838
Endoscopic Surveillance Is a Viable Alternative Management Strategy for Patients with Localised Small Non-Functional Low Grade Duodenal Neuroendocrine Tumours (dNETs) (Conference Paper)
Exarchou, K., Howes, N., Moore, A., Duckworth, C. A., & Pritchard, D. M. (2019). Endoscopic Surveillance Is a Viable Alternative Management Strategy for Patients with Localised Small Non-Functional Low Grade Duodenal Neuroendocrine Tumours (dNETs). In NEUROENDOCRINOLOGY Vol. 108 (pp. 56). Retrieved from https://www.webofscience.com/
Endoscopic surveillance is a viable alternative management strategy for patients with localised small non-functional low grade duodenal neuroendocrine tumours (dNETs) (Conference Paper)
Exarchou, K., Howes, N., Moore, A., Duckworth, C. A., & Pritchard, D. M. (2019). Endoscopic surveillance is a viable alternative management strategy for patients with localised small non-functional low grade duodenal neuroendocrine tumours (dNETs). In BRITISH JOURNAL OF SURGERY Vol. 106 (pp. 74). Retrieved from https://www.webofscience.com/
Netazepide, a Gastrin/CCK2 Receptor Antagonist, Can Eradicate Gastric Neuroendocrine Tumours in PatientsWith Autoimmune Chronic Atrophic Gastritis (Conference Paper)
Boyce, M., Moore, A. R., Parsons, B., Lloyd, K., Sagatun, L., Varro, A., . . . Pritchard, D. M. (2019). Netazepide, a Gastrin/CCK2 Receptor Antagonist, Can Eradicate Gastric Neuroendocrine Tumours in PatientsWith Autoimmune Chronic Atrophic Gastritis. In PANCREAS Vol. 48 (pp. 429). Retrieved from https://www.webofscience.com/
Periodic endoscopic surveillance in patients with low risk Type 1 gastric neuroendocrine tumours (gNETs) also detects associated gastric adenocarcinoma in a subset of patients (Conference Paper)
Exarchou, K., Howes, N., Moore, A., Duckworth, C., & Pritchard, D. M. (2019). Periodic endoscopic surveillance in patients with low risk Type 1 gastric neuroendocrine tumours (gNETs) also detects associated gastric adenocarcinoma in a subset of patients. In BRITISH JOURNAL OF SURGERY Vol. 106 (pp. 85). Retrieved from https://www.webofscience.com/
2018
Smith, C. I., Siggel-King, M. R. F., Ingham, J., Harrison, P., Martin, D. S., Varro, A., . . . Weightman, P. (2018). Application of a quantum cascade laser aperture scanning near-field optical microscope to the study of a cancer cell. ANALYST, 143(24), 5912-5917. doi:10.1039/c8an01183dDOI: 10.1039/c8an01183d
The impact of 68Ga-based PET-CT scanning on the management of patients with sporadic pancreatic neuroendocrine tumours (pNETs) (Journal article)
Cuthbertson, D., Barriuso, J., Pizanais, M., Jaffa, M., Lamarca, A., Vivian, G., . . . Yip, V. (n.d.). The impact of 68Ga-based PET-CT scanning on the management of patients with sporadic pancreatic neuroendocrine tumours (pNETs). Endocrine Abstracts. doi:10.1530/endoabs.60.p18DOI: 10.1530/endoabs.60.p18
Ingham, J., Craig, T., Smith, C. I., Varro, A., Pritchard, D. M., Barrett, S. D., . . . Siggel-King, M. R. F. (2018). Submicron infrared imaging of an oesophageal cancer cell with chemical specificity using an IR-FEL. Biomedical Physics and Engineering Express, 5. doi:10.1088/2057-1976/aaea53DOI: 10.1088/2057-1976/aaea53
Mahalhal, A., Williams, J. M., Johnson, S., Ellaby, N., Duckworth, C. A., Burkitt, M. D., . . . Probert, C. S. (2018). Oral iron exacerbates colitis and influences the intestinal microbiome. PLOS ONE, 13(10). doi:10.1371/journal.pone.0202460DOI: 10.1371/journal.pone.0202460
Contact X-ray Brachytherapy as an Adjunct to a Watch and Wait Approach is an Affordable Alternative to Standard Surgical Management of Rectal Cancer for Patients with a Partial Clinical Response to Chemoradiotherapy (Journal article)
Rao, C., Stewartz, A., Martin, A. P., Collins, B., Pritchard, D. M., Athanasiou, T., & Myint, A. S. (2018). Contact X-ray Brachytherapy as an Adjunct to a Watch and Wait Approach is an Affordable Alternative to Standard Surgical Management of Rectal Cancer for Patients with a Partial Clinical Response to Chemoradiotherapy. CLINICAL ONCOLOGY, 30(10), 625-633. doi:10.1016/j.clon.2018.06.010DOI: 10.1016/j.clon.2018.06.010
Mahalhal, A., Williams, J., Johnson, S., Ellaby, N., Duckworth, C., Burkitt, M., . . . Probert, C. (2018). Oral iron exacerbates colitis and influences the intestinal microbiome. doi:10.1101/385997DOI: 10.1101/385997
Contact X-Ray Brachytherapy in Organ Preservation for Rectal Cancer Reply (Journal article)
Myint, A. S., Smith, F. M., Gollins, S., Rao, C., & Pritchard, D. M. (2018). Contact X-Ray Brachytherapy in Organ Preservation for Rectal Cancer Reply. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 101(3), 743-744. doi:10.1016/j.ijrobp.2018.03.033DOI: 10.1016/j.ijrobp.2018.03.033
Evans, J. P., Winiarski, B. K., Sutton, P. A., Jones, R. P., Ressel, L., Duckworth, C. A., . . . Kitteringham, N. R. (2018). The Nrf2 inhibitor brusatol is a potent antitumour agent in an orthotopic mouse model of colorectal cancer. Oncotarget, 9(43), 27104-27116. doi:10.18632/oncotarget.25497DOI: 10.18632/oncotarget.25497
IDENTIFICATION OF A NOVEL THERAPEUTIC AGENT FOR TREATING IBD GUIDED BY SYSTEMS MEDICINE (Conference Paper)
Burkitt, M., Lloyd, K., Papoutsopoulou, S., Smith, E., Stegmaier, P., Pritchard, D. M., . . . Probert, C. (2018). IDENTIFICATION OF A NOVEL THERAPEUTIC AGENT FOR TREATING IBD GUIDED BY SYSTEMS MEDICINE. In GUT Vol. 67 (pp. A52). doi:10.1136/gutjnl-2018-BSGAbstracts.104DOI: 10.1136/gutjnl-2018-BSGAbstracts.104
Mahalhal, A., Subramanian, S., Pritchard, D. M., & Probert, C. S. (2018). INTESTINAL DYSBIOSIS OCCURS IN IRON DEFICIENCY AS WELL AS ACTIVE IBD. In GUT Vol. 67 (pp. A193). doi:10.1136/gutjnl-2018-BSGAbstracts.384DOI: 10.1136/gutjnl-2018-BSGAbstracts.384
Garalla, H. M., Lertkowit, N., Tiszlavicz, L., Reisz, Z., Holmberg, C., Beynon, R., . . . Varro, A. (2018). Matrix metalloproteinase (MMP)-7 in Barrett's esophagus and esophageal adenocarcinoma: expression, metabolism, and functional significance. Retrieved from https://www.webofscience.com/DOI: 10.14814/phy2.13683
Craig, T., Smith, A. D., Holder, G. M., Ingham, J., Smith, C. I., Varro, A., . . . Siggel-King, M. R. F. (2018). SNOM Imaging of a Crypt-Like Feature in Adenocarcinoma Associated with Barrett's Oesophagus. PHYSICA STATUS SOLIDI B-BASIC SOLID STATE PHYSICS, 255(4). doi:10.1002/pssb.201700518DOI: 10.1002/pssb.201700518
Ingham, J., Pilling, M. J., Craig, T., Siggel-King, M. R. F., Smith, C. I., Gardner, P., . . . Weightman, P. (2018). An evaluation of the application of the aperture infrared SNOM technique to biomedical imaging. Biomedical Physics & Engineering Express, 4(2). doi:10.1088/2057-1976/aaa0deDOI: 10.1088/2057-1976/aaa0de
Myint, A. S., Smith, F. M., Gollins, S., Wong, H., Rao, C., Whitmarsh, K., . . . Pritchard, D. M. (2018). Dose Escalation Using Contact X-ray Brachytherapy After External Beam Radiotherapy as Nonsurgical Treatment Option for Rectal Cancer: Outcomes From a Single-Center Experience. International Journal of Radiation: Oncology - Biology - Physics, 100(3), 565-573. doi:10.1016/j.ijrobp.2017.10.022DOI: 10.1016/j.ijrobp.2017.10.022
Lamarca, A., Pritchard, D. M., Westwood, T., Papaxoinis, G., Nonaka, D., Vinjamuri, S., . . . Mansoor, W. (2018). <SUP>68</SUP>Gallium DOTANOC-PET Imaging in Lung Carcinoids: Impact on Patients' Management. NEUROENDOCRINOLOGY, 106(2), 128-138. doi:10.1159/000472717DOI: 10.1159/000472717
2017
parsons, B. N., Ijaz, U. Z., D'Amore, R., Burkitt, M. D., Eccles, R., Lenzi, L., . . . Pritchard, D. M. (2017). Comparison Of The Human Gastric Microbiota In Hypochlorhydric States Arising As A Result Of Helicobacter pylori-Induced Atrophic Gastritis, Autoimmune Atrophic Gastritis And Proton Pump Inhibitor Use. PLoS Pathogens. doi:10.1101/144907DOI: 10.1101/144907
Parsons, B. N., Ijaz, U. Z., D'Amore, R., Burkitt, M. D., Eccles, R., Lenzi, L., . . . Pritchard, D. M. (2017). Comparison of the human gastric microbiota in hypochlorhydric states arising as a result of Helicobacter pylori-induced atrophic gastritis, autoimmune atrophic gastritis and proton pump inhibitor use. PLoS Pathogens, 13(11). doi:10.1371/journal.ppat.1006653DOI: 10.1371/journal.ppat.1006653
Beg, S., Ragunath, K., Wyman, A., Banks, M., Trudgill, N., Pritchard, M. D., . . . Veitch, A. (2017). Quality standards in upper gastrointestinal endoscopy: a position statement of the British Society of Gastroenterology (BSG) and Association of Upper Gastrointestinal Surgeons of Great Britain and Ireland (AUGIS). GUT, 66(11), 1886-1899. doi:10.1136/gutjnl-2017-314109DOI: 10.1136/gutjnl-2017-314109
Burkitt, M. D., Williams, J. M., Townsend, T., Hough, R., & Pritchard, D. M. (2017). Mice lacking NF-κB1 exhibit marked DNA damage responses and more severe gastric pathology in response to intraperitoneal tamoxifen administration. CELL DEATH & DISEASE, 8. doi:10.1038/cddis.2017.332DOI: 10.1038/cddis.2017.332
Burkitt, M., Williams, J., Townsend, T., Hough, R., Duckworth, C., & Pritchard, D. M. (2017). Mice lacking NF-κB1 exhibit marked DNA damage responses and more severe gastric pathology in response to intraperitoneal tamoxifen administration.. Cell Death and Disease. doi:10.1101/112656DOI: 10.1101/112656
EXPRESSION OF MADCAM-1 IN THE UPPER GASTROINTESTINAL TRACT: IS THERE A ROLE FOR DISRUPTING INTERACTIONS BETWEEN MADCAM-1 AND ALPHA-4/BETA-7 INTEGRIN IN UPPER GI CROHN'S DISEASE? (Conference Paper)
Ahmed, A., Pritchard, D. M., & Burkitt, M. D. (2017). EXPRESSION OF MADCAM-1 IN THE UPPER GASTROINTESTINAL TRACT: IS THERE A ROLE FOR DISRUPTING INTERACTIONS BETWEEN MADCAM-1 AND ALPHA-4/BETA-7 INTEGRIN IN UPPER GI CROHN'S DISEASE?. In GUT Vol. 66 (pp. A236). doi:10.1136/gutjnl-2017-314472.459DOI: 10.1136/gutjnl-2017-314472.459
INFECTION WITH STREPTOCOCCUS GALLOLYTICUS INCREASES APOPTOSIS IN THE MURINE COLON (Conference Paper)
Townsend, T., Burkitt, M., & Pritchard, D. M. (2017). INFECTION WITH STREPTOCOCCUS GALLOLYTICUS INCREASES APOPTOSIS IN THE MURINE COLON. In GUT Vol. 66 (pp. A135). doi:10.1136/gutjnl-2017-314472.265DOI: 10.1136/gutjnl-2017-314472.265
Mahalhal, A., Campbell, B., Pritchard, D. M., & Probert, C. (2017). INFLUENCE OF IRON ON GUT MICROBIAL COMPOSITION IN ACUTE DSS-INDUCED COLITIS IN C57BL/6 MICE. In GUT Vol. 66 (pp. A234). doi:10.1136/gutjnl-2017-314472.456DOI: 10.1136/gutjnl-2017-314472.456
Mahalhal, A., Campbell, B., Pritchard, D. M., & Probert, C. (2017). LONGITUDINAL INVESTIGATION OF MICROBIOTA DYNAMICS IN A MODEL OF MILD CHRONIC DSSINDUCED COLITIS IN WILD-TYPE (WT) C57BL/6 MICE RECEIVING DIETS WITH DIFFERENT IRON CONTENTS. In GUT Vol. 66 (pp. A237). doi:10.1136/gutjnl-2017-314472.463DOI: 10.1136/gutjnl-2017-314472.463
Carr, D. F., Ayehunie, S., Davies, A., Duckworth, C. A., French, S., Hall, N., . . . Pirmohamed, M. (2017). Towards better models and mechanistic biomarkers for drug-induced gastrointestinal injury. PHARMACOLOGY & THERAPEUTICS, 172, 181-194. doi:10.1016/j.pharmthera.2017.01.002DOI: 10.1016/j.pharmthera.2017.01.002
Lemos, L. M. S., Miyajima, F., Castilho, G. R. C., Martins, D. T. O., Pritchard, D. M., & Burkitt, M. D. (2017). Hexane Extracts of Calophyllum brasiliense Inhibit the Development of Gastric Preneoplasia in Helicobacter felis Infected INS-Gas Mice. Frontiers in Pharmacology, 8. doi:10.3389/fphar.2017.00092DOI: 10.3389/fphar.2017.00092
Burkitt, M. D., Duckworth, C. A., Williams, J. M., & Pritchard, D. M. (2017). <i>Helicobacter pylori</i>-induced gastric pathology: insights from <i>in vivo</i> and ex <i>vivo</i> models. DISEASE MODELS & MECHANISMS, 10(2), 89-104. doi:10.1242/dmm.027649DOI: 10.1242/dmm.027649
Myint, A. S., Smith, F. M., Gollins, S. W., Wong, H., Rao, C., Whitmarsh, K., . . . Pritchard, D. M. (2017). Dose escalation using contact X-ray brachytherapy (Papillon) for rectal cancer: does it improve the chance of organ preservation?. BRITISH JOURNAL OF RADIOLOGY, 90(1080). doi:10.1259/bjr.20170175DOI: 10.1259/bjr.20170175
2016
Boyce, M., Lloyd, K. A., & Pritchard, D. M. (2016). Potential clinical indications for a CCK<sub>2</sub> receptor antagonist. CURRENT OPINION IN PHARMACOLOGY, 31, 68-75. doi:10.1016/j.coph.2016.09.002
68Gallium-DOTANOC (68Ga-DOTANOC) positron emission tomography (PET) imaging in Bronchial Carcinoids (BC): multicentre evaluation of its role in clinical practice (Journal article)
Lamarca, A., Pritchard, D. M., Westwood, T., Papaxoinis, G., Vinjamuri, S., Valle, J. W., . . . Mansoor, W. (n.d.). 68Gallium-DOTANOC (68Ga-DOTANOC) positron emission tomography (PET) imaging in Bronchial Carcinoids (BC): multicentre evaluation of its role in clinical practice. Endocrine Abstracts. doi:10.1530/endoabs.46.p2DOI: 10.1530/endoabs.46.p2
Calvete, O., Varro, A., Pritchard, D. M., Barroso, A., Oteo, M., Morcillo, M., . . . Benitez, J. (2016). A knockin mouse model for human ATP4aR703C mutation identified in familial gastric neuroendocrine tumors recapitulates the premalignant condition of the human disease and suggests new therapeutic strategies.. Disease models & mechanisms, 9(9), 975-984. doi:10.1242/dmm.025890DOI: 10.1242/dmm.025890
Lloyd, K. A., Moore, A. R., Parsons, B. N., O'Hara, A., Boyce, M., Dockray, G. J., . . . Pritchard, D. M. (2016). Gastrin-induced miR-222 promotes gastric tumor development by suppressing p27(kip1). ONCOTARGET, 7(29), 45462-45478. doi:10.18632/oncotarget.9990DOI: 10.18632/oncotarget.9990
Importance of the alternative NF-κB activation pathway in inflammation-associated gastrointestinal carcinogenesis (Journal article)
Merga, Y. J., O Hara, A., Burkitt, M. D., Duckworth, C. A., Probert, C. S., Campbell, B. J., & Pritchard, D. M. (2016). Importance of the alternative NF-κB activation pathway in inflammation-associated gastrointestinal carcinogenesis. American Journal of Physiology - Gastrointestinal and Liver Physiology, 310(11), G1081-G1090. doi:10.1152/ajpgi.00026.2016DOI: 10.1152/ajpgi.00026.2016
Williams, J. M., Duckworth, C. A., Vowell, K., Burkitt, M. D., & Pritchard, D. M. (2016). Intestinal Preparation Techniques for Histological Analysis in the Mouse.. Current protocols in mouse biology, 6(2), 148-168. doi:10.1002/cpmo.2DOI: 10.1002/cpmo.2
Pritchard, D. M., & Hooper, M. (2016). Letter: gastric cancer and pernicious anaemia - only a minority of UK pernicious anaemia patients have had a gastroscopy. ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 43(10), 1106-1107. doi:10.1111/apt.13595DOI: 10.1111/apt.13595
Netazepide, a Gastrin/CCK2 Receptor Antagonist, Can Eradicate Gastric Neuroendocrine Tumours in Patients with Autoimmune Chronic Atrophic Gastritis (Conference Paper)
Boyce, M., Moore, A. R., Parsons, B. N., Lloyd, K. A., Sagatun, L., Thomsen, L., . . . Pritchard, D. M. (2016). Netazepide, a Gastrin/CCK2 Receptor Antagonist, Can Eradicate Gastric Neuroendocrine Tumours in Patients with Autoimmune Chronic Atrophic Gastritis. In NEUROENDOCRINOLOGY Vol. 103 (pp. 78). Retrieved from https://www.webofscience.com/
2015
The stomach in health and disease (Journal article)
Hunt, R. H., Camilleri, M., Crowe, S. E., El-Omar, E. M., Fox, J. G., Kuipers, E. J., . . . Tack, J. (2015). The stomach in health and disease. GUT, 64(10), 1650-1668. doi:10.1136/gutjnl-2014-307595DOI: 10.1136/gutjnl-2014-307595
Duckworth, C. A., Guimond, S. E., Sindrewicz, P., Hughes, A. J., French, N. S., Lian, L. -Y., . . . Yu, L. -G. (2015). Chemically modified, non-anticoagulant heparin derivatives are potent galectin-3 binding inhibitors and inhibit circulating galectin-3-promoted metastasis. ONCOTARGET, 6(27), 23671-23687. doi:10.18632/oncotarget.4409DOI: 10.18632/oncotarget.4409
bak deletion stimulates gastric epithelial proliferation and enhances <i>Helicobacter felis</i>-induced gastric atrophy and dysplasia in mice (Journal article)
Duckworth, C. A., Abuderman, A. A., Burkitt, M. D., Williams, J. M., O'Reilly, L. A., & Pritchard, D. M. (2015). bak deletion stimulates gastric epithelial proliferation and enhances <i>Helicobacter felis</i>-induced gastric atrophy and dysplasia in mice. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 309(6), G420-G430. doi:10.1152/ajpgi.00404.2014DOI: 10.1152/ajpgi.00404.2014
Geraghty, J., Thumbs, A., Kankwatira, A., Andrews, T., Moore, A., Malamba, R., . . . Gordon, M. (2015). Helicobacter pylori, HIV and Gastric Hypochlorhydria in the Malawian Population. PloS One, 10(8). doi:10.1371/journal.pone.0132043DOI: 10.1371/journal.pone.0132043
PAK1 modulates a PPARγ/NF-κB cascade in intestinal inflammation (Conference Paper)
Dammann, K., Khare, V., Lang, M., Claudel, T., Harpain, F., Granofszky, N., . . . Gasche, C. (2015). PAK1 modulates a PPARγ/NF-κB cascade in intestinal inflammation. In CANCER RESEARCH Vol. 75. doi:10.1158/1538-7445.AM2015-137DOI: 10.1158/1538-7445.AM2015-137
Kumar, J. D., Steele, I., Moore, A. R., Murugesan, S. V., Rakonczay, Z., Venglovecz, V., . . . Dockray, G. J. (2015). Gastrin stimulates MMP-1 expression in gastric epithelial cells: putative role in gastric epithelial cell migration. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 309(2), G78-G86. doi:10.1152/ajpgi.00084.2015DOI: 10.1152/ajpgi.00084.2015
NF-kappaB1, NF-kappaB2 and c-Rel differentially regulate susceptibility to colitis-associated adenoma development in C57BL/6 mice (Journal article)
Burkitt, M., Hanedi, A. F., Duckworth, C., Williams, J. M., Tang, J. M., O'Reilly, L. A., . . . Pritchard, M. (2015). NF-kappaB1, NF-kappaB2 and c-Rel differentially regulate susceptibility to colitis-associated adenoma development in C57BL/6 mice. The Journal of Pathology, 236(3), 326-336. doi:10.1002/path.4527DOI: 10.1002/path.4527
CONFOCAL ENDOMICROSCOPY DEMONSTRATES INCREASED INTESTINAL PERMEABILITY AND GUT DYSFUNCTION IN PATIENTS WITH ACUTE AND CHRONIC PANCREATITIS (Conference Paper)
Bharucha, S., Geraghty, J., Duckworth, C., Armstrong, J., Szatmary, P., Winn, S., . . . Sutton, R. (2015). CONFOCAL ENDOMICROSCOPY DEMONSTRATES INCREASED INTESTINAL PERMEABILITY AND GUT DYSFUNCTION IN PATIENTS WITH ACUTE AND CHRONIC PANCREATITIS. In GUT Vol. 64 (pp. A307). doi:10.1136/gutjnl-2015-309861.663DOI: 10.1136/gutjnl-2015-309861.663
Murine Models of Helicobacter (pylori or felis)-associated Gastric Cancer. (Journal article)
Duckworth, C. A., Burkitt, M. D., Williams, J. M., Parsons, B. N., Tang, J. M. F., & Pritchard, D. M. (2015). Murine Models of Helicobacter (pylori or felis)-associated Gastric Cancer.. Current protocols in pharmacology, 69, 14.34.1-14.34.35. doi:10.1002/0471141755.ph1434s69DOI: 10.1002/0471141755.ph1434s69
OC-043 Nfkb1 deficiency alters susceptibility to helicobacter spp. induced il-1Β secretion in bone marrow derived dendritic cells (Journal article)
Tang, J. M., Pritchard, D. M., Duckworth, C. A., Caamano, J., & Burkitt, M. D. (2015). OC-043 Nfkb1 deficiency alters susceptibility to helicobacter spp. induced il-1Β secretion in bone marrow derived dendritic cells. Gut, 64(Suppl 1), A22.2-A23. doi:10.1136/gutjnl-2015-309861.43DOI: 10.1136/gutjnl-2015-309861.43
VOLATILE ORGANIC COMPOUND (VOC) PROFILES AS INDICATORS OF EARLY LESIONS IN MURINE COLON CARCINOGENESIS (Conference Paper)
Reade, S., Williams, J. M., Pritchard, D. M., & Probert, C. S. J. (2015). VOLATILE ORGANIC COMPOUND (VOC) PROFILES AS INDICATORS OF EARLY LESIONS IN MURINE COLON CARCINOGENESIS. In GUT Vol. 64 (pp. A374-A375). doi:10.1136/gutjnl-2015-309861.819DOI: 10.1136/gutjnl-2015-309861.819
Exome sequencing identifies ATP4A gene as responsible of an atypical familial type I gastric neuroendocrine tumour (Journal article)
Calvete, O., Reyes, J., Zuniga, S., Paumard-Hernandez, B., Fernandez, V., Bujanda, L., . . . Benitez, J. (2015). Exome sequencing identifies ATP4A gene as responsible of an atypical familial type I gastric neuroendocrine tumour. Human Molecular Genetics, 24(10), 2914-2922. doi:10.1093/hmg/ddv054DOI: 10.1093/hmg/ddv054
Epithelial Cell Shedding and Barrier Function: A Matter of Life and Death at the Small Intestinal Villus Tip (Journal article)
Williams, J. M., Duckworth, C. A., Burkitt, M. D., Watson, A. J. M., Campbell, B. J., & Pritchard, D. M. (2015). Epithelial Cell Shedding and Barrier Function: A Matter of Life and Death at the Small Intestinal Villus Tip. VETERINARY PATHOLOGY, 52(3), 445-455. doi:10.1177/0300985814559404DOI: 10.1177/0300985814559404
242 A Combination of Fasting Serum Gastrin Concentration, Pepsinogen 1/2 Ratio and Helicobacter pylori IgG Antibody Serotype Accurately Predicts Gastric Mucosal Preneoplasia in a Large European Cohort (Journal article)
Moore, A. R., Steele, I., Murugesan, S. V., Tiszlavicz, L., Dockray, G. J., Varro, A., & Pritchard, D. M. (2015). 242 A Combination of Fasting Serum Gastrin Concentration, Pepsinogen 1/2 Ratio and Helicobacter pylori IgG Antibody Serotype Accurately Predicts Gastric Mucosal Preneoplasia in a Large European Cohort. Gastroenterology, 148(4), S-54. doi:10.1016/s0016-5085(15)30187-6DOI: 10.1016/s0016-5085(15)30187-6
25 Intestinal Epithelial Cell Specific Deletion of Nfkb2 Protects Against Immune Cell Derived Damage-Inducing Factors in an Enteroid and Bone Marrow Derived Dendritic Cell Co-Culture System (Journal article)
Burkitt, M. D., Jones, L. G., Caamano, J., Pritchard, D. M., & Duckworth, C. A. (2015). 25 Intestinal Epithelial Cell Specific Deletion of Nfkb2 Protects Against Immune Cell Derived Damage-Inducing Factors in an Enteroid and Bone Marrow Derived Dendritic Cell Co-Culture System. Gastroenterology, 148(4). doi:10.1016/s0016-5085(15)30025-1DOI: 10.1016/s0016-5085(15)30025-1
606 NFKB1 Deficiency Alters Susceptibility to Helicobacter spp. Induced IL-1β Secretion in Bone Marrow Derived Dendritic Cells (Journal article)
Tang, J. M., Duckworth, C. A., Pritchard, D. M., Caamano, J., & Burkitt, M. D. (2015). 606 NFKB1 Deficiency Alters Susceptibility to Helicobacter spp. Induced IL-1β Secretion in Bone Marrow Derived Dendritic Cells. Gastroenterology, 148(4), S-118. doi:10.1016/s0016-5085(15)30409-1DOI: 10.1016/s0016-5085(15)30409-1
760 Confocal Endomicroscopy Demonstrates Increased Intestinal Permeability and Gut Dysfunction in Patients With Acute and Chronic Pancreatitis (Journal article)
Bharucha, S., Geraghty, J., Duckworth, C. A., Armstrong, J., Szatmary, P., Winn, S. A., . . . Sutton, R. (2015). 760 Confocal Endomicroscopy Demonstrates Increased Intestinal Permeability and Gut Dysfunction in Patients With Acute and Chronic Pancreatitis. Gastroenterology, 148(4), S-145. doi:10.1016/s0016-5085(15)30495-9DOI: 10.1016/s0016-5085(15)30495-9
Sa1821 Gastrin Increases miR-222 Expression in AGSGR Cells In Vitro and in the Stomachs of Hypergastrinemic INS-GAS Mice and Humans In Vivo via Activation of the CCK2 Receptor (Journal article)
Lloyd, K. A., Moore, A. R., O'Hara, A., Boyce, M. J., Varro, A., & Pritchard, D. M. (2015). Sa1821 Gastrin Increases miR-222 Expression in AGSGR Cells In Vitro and in the Stomachs of Hypergastrinemic INS-GAS Mice and Humans In Vivo via Activation of the CCK2 Receptor. Gastroenterology, 148(4), S-341. doi:10.1016/s0016-5085(15)31137-9DOI: 10.1016/s0016-5085(15)31137-9
Sa1824 Identification of Potential Biomarkers of Netazepide (YF476) Treatment of Type I Gastric Neuroendocrine Tumours (Journal article)
Moore, A. R., Parsons, B. N., Boyce, M. J., Rainbow, L., Fang, Y., Varro, A., . . . Pritchard, D. M. (2015). Sa1824 Identification of Potential Biomarkers of Netazepide (YF476) Treatment of Type I Gastric Neuroendocrine Tumours. Gastroenterology, 148(4), S-342. doi:10.1016/s0016-5085(15)31140-9DOI: 10.1016/s0016-5085(15)31140-9
Su1927 Passive Transmission of Helicobacter felis Occurs in a Specific Pathogen Free (SPF) Laboratory Environment (Journal article)
Tang, J. M., Parsons, B. N., Williams, J. M., Pritchard, D. M., & Burkitt, M. D. (2015). Su1927 Passive Transmission of Helicobacter felis Occurs in a Specific Pathogen Free (SPF) Laboratory Environment. Gastroenterology, 148(4), S-553. doi:10.1016/s0016-5085(15)31857-6DOI: 10.1016/s0016-5085(15)31857-6
Su1973 Tamoxifen Induced Gastric Atrophy Is Regulated by the NF-κB Subunit NFKB1 (Journal article)
Williams, J. M., Norman, R., Tang, J. M., Caamano, J., Duckworth, C. A., Pritchard, D. M., & Burkitt, M. D. (2015). Su1973 Tamoxifen Induced Gastric Atrophy Is Regulated by the NF-κB Subunit NFKB1. Gastroenterology, 148(4), S-565. doi:10.1016/s0016-5085(15)31902-8DOI: 10.1016/s0016-5085(15)31902-8
<i>NFKB1</i> Deficiency Alters Susceptibility to <i>Helicobacter spp</i>. Induced IL-1β Secretion in Bone Marrow Derived Dendritic Cells (Conference Paper)
Tang, J. M., Duckworth, C. A., Pritchard, D. M., Caamano, J., & Burkitt, M. D. (2015). <i>NFKB1</i> Deficiency Alters Susceptibility to <i>Helicobacter spp</i>. Induced IL-1β Secretion in Bone Marrow Derived Dendritic Cells. In GASTROENTEROLOGY Vol. 148 (pp. S118). Retrieved from https://www.webofscience.com/
A Combination of Fasting Serum Gastrin Concentration, Pepsinogen 1/2 Ratio and <i>Helicobacter pylori</i> IgG Antibody Serotype Accurately Predicts Gastric Mucosal Preneoplasia in a Large European Cohort (Conference Paper)
Moore, A. R., Steele, I., Murugesan, S. V., Tiszlavicz, L., Dockray, G. J., Varro, A., & Pritchard, D. M. (2015). A Combination of Fasting Serum Gastrin Concentration, Pepsinogen 1/2 Ratio and <i>Helicobacter pylori</i> IgG Antibody Serotype Accurately Predicts Gastric Mucosal Preneoplasia in a Large European Cohort. In GASTROENTEROLOGY Vol. 148 (pp. S54). Retrieved from https://www.webofscience.com/
Confocal Endomicroscopy Demonstrates Increased Intestinal Permeability and Gut Dysfunction in Patients With Acute and Chronic Pancreatitis (Conference Paper)
Bharucha, S., Geraghty, J., Duckworth, C. A., Armstrong, J., Szatmary, P., Winn, S. A., . . . Sutton, R. (2015). Confocal Endomicroscopy Demonstrates Increased Intestinal Permeability and Gut Dysfunction in Patients With Acute and Chronic Pancreatitis. In GASTROENTEROLOGY Vol. 148 (pp. S145). Retrieved from https://www.webofscience.com/
Gastrin Increases miR-222 Expression in AGS<sub>GR</sub> Cells <i>In Vitro</i> and in the Stomachs of Hypergastrinemic INS-GAS Mice and Humans <i>In Vivo</i> via Activation of the CCK2 Receptor (Conference Paper)
Lloyd, K. A., Moore, A. R., O'Hara, A., Boyce, M. J., Varro, A., & Pritchard, D. M. (2015). Gastrin Increases miR-222 Expression in AGS<sub>GR</sub> Cells <i>In Vitro</i> and in the Stomachs of Hypergastrinemic INS-GAS Mice and Humans <i>In Vivo</i> via Activation of the CCK2 Receptor. In GASTROENTEROLOGY Vol. 148 (pp. S341). Retrieved from https://www.webofscience.com/
Intestinal Epithelial Cell Specific Deletion of Nfkb2 Protects Against Immune Cell Derived Damage-Inducing Factors in an Enteroid and Bone Marrow Derived Dendritic Cell Co-Culture System (Conference Paper)
Burkitt, M. D., Jones, L. G., Caamano, J., Pritchard, D. M., & Duckworth, C. A. (2015). Intestinal Epithelial Cell Specific Deletion of Nfkb2 Protects Against Immune Cell Derived Damage-Inducing Factors in an Enteroid and Bone Marrow Derived Dendritic Cell Co-Culture System. In GASTROENTEROLOGY Vol. 148 (pp. S8-S9). Retrieved from https://www.webofscience.com/
Passive Transmission of <i>Helicobacter felis</i> Occurs in a Specific Pathogen Free (SPF) Laboratory Environment (Conference Paper)
Tang, J. M., Parsons, B. N., Williams, J. M., Pritchard, D. M., & Burkitt, M. D. (2015). Passive Transmission of <i>Helicobacter felis</i> Occurs in a Specific Pathogen Free (SPF) Laboratory Environment. In GASTROENTEROLOGY Vol. 148 (pp. S553). Retrieved from https://www.webofscience.com/
Polymorphisms in the <i>RELB</i> Gene Identify a Haplotype Associated With Reduced Risk of Pangastric Atrophy (Conference Paper)
O'Hara, A., Burkitt, M. D., Carr, D. F., Alfirevic, A., Moore, A. R., Murugesan, S. V., . . . Pritchard, D. M. (2015). Polymorphisms in the <i>RELB</i> Gene Identify a Haplotype Associated With Reduced Risk of Pangastric Atrophy. In GASTROENTEROLOGY Vol. 148 (pp. S566). Retrieved from https://www.webofscience.com/
Tamoxifen Induced Gastric Atrophy Is Regulated by the NF-κB Subunit NFKB1 (Conference Paper)
Williams, J. M., Norman, R., Tang, J. M., Caamano, J., Duckworth, C. A., Pritchard, D. M., & Burkitt, M. D. (2015). Tamoxifen Induced Gastric Atrophy Is Regulated by the NF-κB Subunit NFKB1. In GASTROENTEROLOGY Vol. 148 (pp. S565). Retrieved from https://www.webofscience.com/
2014
Peanut agglutinin appearance in the blood circulation after peanut ingestion mimics the action of endogenous galactin-3 to promote metastasis by interaction with cancer-associated MUC1 (Journal article)
Zhao, Q., Duckworth, C. A., Wang, W. K., Guo, X., Barrow, H., Pritchard, D. M., . . . Yu, L. G. (2014). Peanut agglutinin appearance in the blood circulation after peanut ingestion mimics the action of endogenous galactin-3 to promote metastasis by interaction with cancer-associated MUC1. Carcinogenesis, 35(12), 2815-2821. doi:10.1093/carcin/bgu216DOI: 10.1093/carcin/bgu216
Serial surveillance of carcinoid heart disease: factors associated with echocardiographic progression and mortality (Journal article)
Dobson, R., Burgess, M. I., Valle, J. W., Pritchard, D. M., Vora, J., Wong, C., . . . Cuthbertson, D. J. (2014). Serial surveillance of carcinoid heart disease: factors associated with echocardiographic progression and mortality. British Journal of Cancer, 111(09), 1703-1709. doi:10.1038/bjc.2014.468DOI: 10.1038/bjc.2014.468
Analysis of Clinical Isolates of Helicobacter pylori in Pakistan Reveals High Degrees of Pathogenicity and High Frequencies of Antibiotic Resistance (Journal article)
Rasheed, F., Campbell, B. J., Alfizah, H., Varro, A., Zahra, R., Yamaoka, Y., & Pritchard, D. M. (2014). Analysis of Clinical Isolates of Helicobacter pylori in Pakistan Reveals High Degrees of Pathogenicity and High Frequencies of Antibiotic Resistance. Helicobacter, 19(5), 387-399. doi:10.1111/hel.12142DOI: 10.1111/hel.12142
The clinical presentation and management of carcinoid heart disease (Journal article)
Dobson, R., Burgess, M. I., Pritchard, D. M., & Cuthbertson, D. J. (2014). The clinical presentation and management of carcinoid heart disease. INTERNATIONAL JOURNAL OF CARDIOLOGY, 173(1), 29-32. doi:10.1016/j.ijcard.2014.02.037DOI: 10.1016/j.ijcard.2014.02.037
Circulating galectins-2,-4 and-8 in cancer patients make important contributions to the increased circulation of several cytokines and chemokines that promote angiogenesis and metastasis (Journal article)
Chen, C., Duckworth, C. A., Fu, B., Pritchard, D. M., Rhodes, J. M., & Yu, L. -G. (2014). Circulating galectins-2,-4 and-8 in cancer patients make important contributions to the increased circulation of several cytokines and chemokines that promote angiogenesis and metastasis. BRITISH JOURNAL OF CANCER, 110(3), 741-752. doi:10.1038/bjc.2013.793DOI: 10.1038/bjc.2013.793
Circulating galectins -2, -4 and -8 in cancer patients make important contributions to the increased circulation of several cytokines and chemokines that promote angiogenesis and metastasis (Journal article)
Chen, C., Duckworth, C. A., Fu, B., Pritchard, D. M., Rhodes, J. M., & Yu, L. G. (2014). Circulating galectins -2, -4 and -8 in cancer patients make important contributions to the increased circulation of several cytokines and chemokines that promote angiogenesis and metastasis. Br J Cancer, 110(3), 741-752. doi:10.1038/bjc.2013.793DOI: 10.1038/bjc.2013.793
2013
Signaling mediated by the NF-κB sub-units NF-κB1, NF-κB2 and c-Rel differentially regulate <i>Helicobacter felis</i>-induced gastric carcinogenesis in C57BL/6 mice (Journal article)
Burkitt, M. D., Williams, J. M., Duckworth, C. A., O'Hara, A., Hanedi, A., Varro, A., . . . Pritchard, D. M. (2013). Signaling mediated by the NF-κB sub-units NF-κB1, NF-κB2 and c-Rel differentially regulate <i>Helicobacter felis</i>-induced gastric carcinogenesis in C57BL/6 mice. ONCOGENE, 32(50), 5563-5573. doi:10.1038/onc.2013.334DOI: 10.1038/onc.2013.334
A mouse model of pathological small intestinal epithelial cell apoptosis and shedding induced by systemic administration of lipopolysaccharide (Journal article)
Williams, J. M., Duckworth, C. A., Watson, A. J. M., Frey, M. R., Miguel, J. C., Burkitt, M. D., . . . Pritchard, D. M. (2013). A mouse model of pathological small intestinal epithelial cell apoptosis and shedding induced by systemic administration of lipopolysaccharide. DISEASE MODELS & MECHANISMS, 6(6), 1388-1399. doi:10.1242/dmm.013284DOI: 10.1242/dmm.013284
Proteomic profiling of a mouse model of acute intestinal <i>Apc</i> deletion leads to identification of potential novel biomarkers of human colorectal cancer (CRC) (Journal article)
Hammoudi, A., Song, F., Reed, K. R., Jenkins, R. E., Meniel, V. S., Watson, A. J. M., . . . Jenkins, J. R. (2013). Proteomic profiling of a mouse model of acute intestinal <i>Apc</i> deletion leads to identification of potential novel biomarkers of human colorectal cancer (CRC). BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 440(3), 364-370. doi:10.1016/j.bbrc.2013.08.076DOI: 10.1016/j.bbrc.2013.08.076
Crabtree, J. E., Jeremy, A. H. T., Duval, C., Dixon, M. F., Danjo, K., Carr, I. M., . . . Robinson, P. A. (2013). Effects of EGFR Inhibitor on Helicobacter pylori Induced Gastric Epithelial Pathology in Vivo.. Pathogens (Basel, Switzerland), 2(4), 571-590. doi:10.3390/pathogens2040571DOI: 10.3390/pathogens2040571
Netazepide, a Gastrin Receptor Antagonist, Normalises Tumour Biomarkers and Causes Regression of Type 1 Gastric Neuroendocrine Tumours in a Nonrandomised Trial of Patients with Chronic Atrophic Gastritis (Journal article)
Moore, A. R., Boyce, M., Steele, I. A., Campbell, F., Varro, A., & Pritchard, D. M. (2013). Netazepide, a Gastrin Receptor Antagonist, Normalises Tumour Biomarkers and Causes Regression of Type 1 Gastric Neuroendocrine Tumours in a Nonrandomised Trial of Patients with Chronic Atrophic Gastritis. PLOS ONE, 8(10). doi:10.1371/journal.pone.0076462DOI: 10.1371/journal.pone.0076462
The Association of a Panel of Biomarkers with the Presence and Severity of Carcinoid Heart Disease: A Cross-Sectional Study (Journal article)
Dobson, R., Burgess, M. I., Banks, M., Pritchard, D. M., Vora, J., Valle, J. W., . . . Cuthbertson, D. J. (2013). The Association of a Panel of Biomarkers with the Presence and Severity of Carcinoid Heart Disease: A Cross-Sectional Study. PLOS ONE, 8(9). doi:10.1371/journal.pone.0073679DOI: 10.1371/journal.pone.0073679
752 Deletion of Specific NFκB Proteins Regulates Susceptibility to Developing Colitis Associated Cancer in C57BL/6 Mice As a Result of Altered Inflammatory and DNA Damage Responses (Journal article)
Hanedi, A., Burkitt, M. D., Williams, J. M., Duckworth, C. A., Caamano, J., & Pritchard, D. M. (2013). 752 Deletion of Specific NFκB Proteins Regulates Susceptibility to Developing Colitis Associated Cancer in C57BL/6 Mice As a Result of Altered Inflammatory and DNA Damage Responses. Gastroenterology, 144(5), S-136. doi:10.1016/s0016-5085(13)60492-8DOI: 10.1016/s0016-5085(13)60492-8
Mo1807 Lipopolysaccharide Induces Small Intestinal Epithelial Cell Apoptosis and Shedding by a TLR4 and TNFR1 Dependent Mechanism, Which Is Regulated by NFκB Signalling (Journal article)
Williams, J. M., Duckworth, C. A., Campbell, B. J., Frey, M. R., Miguel, J. C., Burkitt, M. D., . . . Pritchard, D. M. (2013). Mo1807 Lipopolysaccharide Induces Small Intestinal Epithelial Cell Apoptosis and Shedding by a TLR4 and TNFR1 Dependent Mechanism, Which Is Regulated by NFκB Signalling. Gastroenterology, 144(5), S-668. doi:10.1016/s0016-5085(13)62476-2DOI: 10.1016/s0016-5085(13)62476-2
Sa2016 Netazepide, a Gastrin/CCK-2 Receptor Antagonist, Causes Regression of Type 1 Gastric Neuroendocrine Tumors and Reduces Expression of Chromogranin a and Histidine Decarboxylase Genes in Chronic Atrophic Gastritis (Journal article)
Moore, A. R., Boyce, M. J., Steele, I., Campbell, F., Varro, A., & Pritchard, D. M. (2013). Sa2016 Netazepide, a Gastrin/CCK-2 Receptor Antagonist, Causes Regression of Type 1 Gastric Neuroendocrine Tumors and Reduces Expression of Chromogranin a and Histidine Decarboxylase Genes in Chronic Atrophic Gastritis. Gastroenterology, 144(5), S-360. doi:10.1016/s0016-5085(13)61325-6DOI: 10.1016/s0016-5085(13)61325-6
The role of plasminogen activator inhibitor-1 in gastric mucosal protection (Journal article)
Kenny, S., Steele, I., Lyons, S., Moore, A. R., Murugesan, S. V., Tiszlavicz, L., . . . Dockray, G. J. (2013). The role of plasminogen activator inhibitor-1 in gastric mucosal protection. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 304(9), G814-G822. doi:10.1152/ajpgi.00017.2013DOI: 10.1152/ajpgi.00017.2013
Acute WNT signalling activation perturbs differentiation within the adult stomach and rapidly leads to tumour formation (Journal article)
Radulescu, S., Ridgway, R. A., Cordero, J., Athineos, D., Salgueiro, P., Poulsom, R., . . . Sansom, O. J. (2013). Acute WNT signalling activation perturbs differentiation within the adult stomach and rapidly leads to tumour formation. ONCOGENE, 32(16), 2048-2057. doi:10.1038/onc.2012.224DOI: 10.1038/onc.2012.224
Peptide receptor radionuclide therapy with <SUP>90</SUP>Y-DOTATATE/<SUP>90</SUP>Y-DOTATOC in patients with progressive metastatic neuroendocrine tumours: assessment of response, survival and toxicity (Journal article)
Vinjamuri, S., Gilbert, T. M., Banks, M., McKane, G., Maltby, P., Poston, G., . . . Cuthbertson, D. J. (2013). Peptide receptor radionuclide therapy with <SUP>90</SUP>Y-DOTATATE/<SUP>90</SUP>Y-DOTATOC in patients with progressive metastatic neuroendocrine tumours: assessment of response, survival and toxicity. BRITISH JOURNAL OF CANCER, 108(7), 1440-1448. doi:10.1038/bjc.2013.103DOI: 10.1038/bjc.2013.103
Correlation between a short-term intravenous octreotide suppression test and response to antrectomy in patients with type-1 gastric neuroendocrine tumours (Journal article)
Murugesan, S. V., Steele, I. A., Dimaline, R., Poston, G. J., Shrotri, M., Campbell, F., . . . Pritchard, D. M. (2013). Correlation between a short-term intravenous octreotide suppression test and response to antrectomy in patients with type-1 gastric neuroendocrine tumours. EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, 25(4), 474-481. doi:10.1097/MEG.0b013e32835cec52DOI: 10.1097/MEG.0b013e32835cec52
Increased Circulation of Galectin-3 in Cancer Induces Secretion of Metastasis-Promoting Cytokines from Blood Vascular Endothelium (Journal article)
Chen, C., Duckworth, C. A., Zhao, Q., Pritchard, D. M., Rhodes, J. M., & Yu, L. -G. (2013). Increased Circulation of Galectin-3 in Cancer Induces Secretion of Metastasis-Promoting Cytokines from Blood Vascular Endothelium. CLINICAL CANCER RESEARCH, 19(7), 1693-1704. doi:10.1158/1078-0432.CCR-12-2940DOI: 10.1158/1078-0432.CCR-12-2940
Near-field optical microscopy with an infra-red free electron laser applied to cancer diagnosis (Journal article)
Smith, A. D., Siggel-King, M. R. F., Holder, G. M., Cricenti, A., Luce, M., Harrison, P., . . . Weightman, P. (2013). Near-field optical microscopy with an infra-red free electron laser applied to cancer diagnosis. APPLIED PHYSICS LETTERS, 102(5). doi:10.1063/1.4790436DOI: 10.1063/1.4790436
<i>CYP2C19*17</i> Gain-of-Function Polymorphism Is Associated With Peptic Ulcer Disease (Journal article)
Musumba, C. O., Jorgensen, A., Sutton, L., Van Eker, D., Zhang, E., O'Hara, N., . . . Pirmohamed, M. (2013). <i>CYP2C19*17</i> Gain-of-Function Polymorphism Is Associated With Peptic Ulcer Disease. CLINICAL PHARMACOLOGY & THERAPEUTICS, 93(2), 195-203. doi:10.1038/clpt.2012.215DOI: 10.1038/clpt.2012.215
Correction: Netazepide, a Gastrin Receptor Antagonist, Normalises Tumour Biomarkers and Causes Regression of Type 1 Gastric Neuroendocrine Tumours in a Nonrandomised Trial of Patients with Chronic Atrophic Gastritis (Journal article)
Correction: Netazepide, a Gastrin Receptor Antagonist, Normalises Tumour Biomarkers and Causes Regression of Type 1 Gastric Neuroendocrine Tumours in a Nonrandomised Trial of Patients with Chronic Atrophic Gastritis (2013). PloS one, 8(11).
Progastrin-Induced Secretion of Insulin-Like Growth Factor 2 From Colonic Myofibroblasts Stimulates Colonic Epithelial Proliferation in Mice (Journal article)
Duckworth, C. A., Clyde, D., Worthley, D. L., Wang, T. C., Varro, A., & Pritchard, D. M. (2013). Progastrin-Induced Secretion of Insulin-Like Growth Factor 2 From Colonic Myofibroblasts Stimulates Colonic Epithelial Proliferation in Mice. GASTROENTEROLOGY, 145(1), 197-+. doi:10.1053/j.gastro.2013.03.012DOI: 10.1053/j.gastro.2013.03.012
2012
Gastrin receptor pharmacology. (Journal article)
Dockray, G. J., Moore, A., Varro, A., & Pritchard, D. M. (2012). Gastrin receptor pharmacology.. Current gastroenterology reports, 14(6), 453-459. doi:10.1007/s11894-012-0293-1DOI: 10.1007/s11894-012-0293-1
Gastric <i>Helicobacter</i> Infection Induces Iron Deficiency in the INS-GAS Mouse (Journal article)
Thomson, M. J., Pritchard, D. M., Boxall, S. A., Abuderman, A. A., Williams, J. M., Varro, A., & Crabtree, J. E. (2012). Gastric <i>Helicobacter</i> Infection Induces Iron Deficiency in the INS-GAS Mouse. PLOS ONE, 7(11). doi:10.1371/journal.pone.0050194DOI: 10.1371/journal.pone.0050194
CD24 is expressed in gastric parietal cells and regulates apoptosis and the response to <i>Helicobacter felis</i> infection in the murine stomach (Journal article)
Duckworth, C. A., Clyde, D., & Pritchard, D. M. (2012). CD24 is expressed in gastric parietal cells and regulates apoptosis and the response to <i>Helicobacter felis</i> infection in the murine stomach. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 303(8), G915-G926. doi:10.1152/ajpgi.00068.2012DOI: 10.1152/ajpgi.00068.2012
Letter: are idiopathic (non-NSAID, non-Helicobacter pylori) ulcers really increasing? Authors' reply (Journal article)
Musumba, C., Hopkins, M., Pritchard, D. M., & Pirmohamed, M. (2012). Letter: are idiopathic (non-NSAID, non-Helicobacter pylori) ulcers really increasing? Authors' reply. ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 36(6), 601-602. doi:10.1111/apt.12001DOI: 10.1111/apt.12001
Commentary: changing aetiology of peptic ulcers - author's reply (Journal article)
Musumba, C., Pritchard, D. M., & Pirmohamed, M. (2012). Commentary: changing aetiology of peptic ulcers - author's reply. ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 36(3), 292-293. doi:10.1111/j.1365-2036.2012.05176.xDOI: 10.1111/j.1365-2036.2012.05176.x
Local barrier dysfunction identified by confocal laser endomicroscopy predicts relapse in inflammatory bowel disease (Journal article)
Kiesslich, R., Duckworth, C. A., Moussata, D., Gloeckner, A., Lim, L. G., Goetz, M., . . . Watson, A. J. M. (2012). Local barrier dysfunction identified by confocal laser endomicroscopy predicts relapse in inflammatory bowel disease. GUT, 61(8), 1146-1153. doi:10.1136/gutjnl-2011-300695DOI: 10.1136/gutjnl-2011-300695
Local barrier dysfunction identified by confocal laser endomicroscopy predicts relapse in inflammatory bowel disease (Journal article)
Kiesslich, R., Duckworth, C. A., Moussata, D., Gloeckner, A., Lim, L. G., Goetz, M., . . . Watson, A. J. M. (2012). Local barrier dysfunction identified by confocal laser endomicroscopy predicts relapse in inflammatory bowel disease. Gut, 61(8), 1146-1153. doi:10.1136/gutjnl-2011-300695DOI: 10.1136/gutjnl-2011-300695
CYP2C19*17 GAIN OF FUNCTION MUTATION IS ASSOCIATED WITH PEPTIC ULCER DISEASE (Journal article)
Musumba, C. O., Eker, D. V., Jorgensen, A., Pritchard, D. M., & Pirmohamed, M. (2012). CYP2C19*17 GAIN OF FUNCTION MUTATION IS ASSOCIATED WITH PEPTIC ULCER DISEASE. GUT, 61, A363. doi:10.1136/gutjnl-2012-302514d.165DOI: 10.1136/gutjnl-2012-302514d.165
Pro-GRP-Derived Peptides Are Expressed in Colorectal Cancer Cells and Tumors and Are Biologically Active <i>in Vivo</i> (Journal article)
Patel, O., Clyde, D., Chang, M., Nordlund, M. S., Steel, R., Kemp, B. E., . . . Baldwin, G. S. (2012). Pro-GRP-Derived Peptides Are Expressed in Colorectal Cancer Cells and Tumors and Are Biologically Active <i>in Vivo</i>. ENDOCRINOLOGY, 153(3), 1082-1092. doi:10.1210/en.2011-1875DOI: 10.1210/en.2011-1875
Chemically-induced apoptosis: p21 and p53 as determinants of enterotoxin activity (vol 103, pg 19, 1998) (Journal article)
Pritchard, D. M., Jackman, A., Potten, C. S., & Hickman, J. A. (2012). Chemically-induced apoptosis: p21 and p53 as determinants of enterotoxin activity (vol 103, pg 19, 1998). TOXICOLOGY LETTERS, 208(1), 75. doi:10.1016/j.toxlet.2011.10.009DOI: 10.1016/j.toxlet.2011.10.009
The relative contribution of NSAIDs and Helicobacter pylori to the aetiology of endoscopically-diagnosed peptic ulcer disease: observations from a tertiary referral hospital in the UK between 2005 and 2010 (Journal article)
Musumba, C., Jorgensen, A., Sutton, L., Van Eker, D., Moorcroft, J., Hopkins, M., . . . Pirmohamed, M. (2012). The relative contribution of NSAIDs and Helicobacter pylori to the aetiology of endoscopically-diagnosed peptic ulcer disease: observations from a tertiary referral hospital in the UK between 2005 and 2010. ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 36(1), 48-56. doi:10.1111/j.1365-2036.2012.05118.xDOI: 10.1111/j.1365-2036.2012.05118.x
2011
Gastrin stimulates expression of plasminogen activator inhibitor-1 in gastric epithelial cells (Journal article)
Norsett, K. G., Steele, I., Duval, C., Sammut, S. J., Murugesan, S. V. M., Kenny, S., . . . Varro, A. (2011). Gastrin stimulates expression of plasminogen activator inhibitor-1 in gastric epithelial cells. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 301(3), G446-G453. doi:10.1152/ajpgi.00527.2010DOI: 10.1152/ajpgi.00527.2010
IFN-γ Inhibits Gastric Carcinogenesis by Inducing Epithelial Cell Autophagy and T-Cell Apoptosis (Journal article)
Tu, S. P., Quante, M., Bhagat, G., Takaishi, S., Cui, G., Yang, X. D., . . . Wang, T. C. (2011). IFN-γ Inhibits Gastric Carcinogenesis by Inducing Epithelial Cell Autophagy and T-Cell Apoptosis. CANCER RESEARCH, 71(12), 4247-4259. doi:10.1158/0008-5472.CAN-10-4009DOI: 10.1158/0008-5472.CAN-10-4009
Bak Deficiency Alters Gastric Epithelial Homeostasis and Modulates the Consequences of Helicobacter felis Infection In Vivo (Journal article)
Duckworth, C. A., Abuderman, A. A., Burkitt, M. D., & Pritchard, D. M. (2011). Bak Deficiency Alters Gastric Epithelial Homeostasis and Modulates the Consequences of Helicobacter felis Infection In Vivo. Gastroenterology, 140(5), S-824. doi:10.1016/s0016-5085(11)63414-8DOI: 10.1016/s0016-5085(11)63414-8
CD24 Co-Localises With DCAMKL-1 in the Intestine and Regulates Epithelial Apoptosis and Crypt Regeneration Following Damage Inducing Stimuli (Journal article)
Duckworth, C. A., Clyde, D., & Pritchard, D. M. (2011). CD24 Co-Localises With DCAMKL-1 in the Intestine and Regulates Epithelial Apoptosis and Crypt Regeneration Following Damage Inducing Stimuli. Gastroenterology, 140(5), S-6. doi:10.1016/s0016-5085(11)60026-7DOI: 10.1016/s0016-5085(11)60026-7
Classical and Alternative Pathway Nuclear Factor-κB Signalling Differentially Regulate Gastric Epithelial Responses to Helicobacter felis Infection (Journal article)
Burkitt, M. D., Varro, A., Caamano, J., & Pritchard, D. M. (2011). Classical and Alternative Pathway Nuclear Factor-κB Signalling Differentially Regulate Gastric Epithelial Responses to Helicobacter felis Infection. Gastroenterology, 140(5), S-673. doi:10.1016/s0016-5085(11)62791-1DOI: 10.1016/s0016-5085(11)62791-1
Classical and Alternative Pathway Nuclear Factor-κB Signalling Regulate Gastric Epithelial Responses to γ-Irradiation (Journal article)
Burkitt, M. D., Duckworth, C. A., Varro, A., Caamano, J., & Pritchard, D. M. (2011). Classical and Alternative Pathway Nuclear Factor-κB Signalling Regulate Gastric Epithelial Responses to γ-Irradiation. Gastroenterology, 140(5), S-823. doi:10.1016/s0016-5085(11)63410-0DOI: 10.1016/s0016-5085(11)63410-0
Determinants of Human Fasting Serum Gastrin Concentration- Interaction Between H. pylori Infection, Gastric Preneoplastic Pathology and Proton Pump Inhibitor Use (Journal article)
Murugesan, S. V., Steele, I., Tiszlavicz, L., Farragher, T., Moore, A. R., Pritchard, D. M., & Varro, A. (2011). Determinants of Human Fasting Serum Gastrin Concentration- Interaction Between H. pylori Infection, Gastric Preneoplastic Pathology and Proton Pump Inhibitor Use. Gastroenterology, 140(5), S-729. doi:10.1016/s0016-5085(11)63030-8DOI: 10.1016/s0016-5085(11)63030-8
Factors That Determine the Sensitivity of Rapid Urease Tests for the Detection of Helicobacter pylori Infection (Journal article)
Murugesan, S. V., Steele, I., Tiszlavicz, L., Farragher, T., Moore, A. R., Varro, A., & Pritchard, D. M. (2011). Factors That Determine the Sensitivity of Rapid Urease Tests for the Detection of Helicobacter pylori Infection. Gastroenterology, 140(5), S-879. doi:10.1016/s0016-5085(11)63654-8DOI: 10.1016/s0016-5085(11)63654-8
Progastrin Stimulates Colonic Myofibroblast Proliferation In Vitro and Its Transgenic Overexpression Increases Colonic Myofibroblast Abundance In Vivo (Journal article)
Clyde, D., Duckworth, C. A., Varro, A., Wang, T. C., & Pritchard, D. M. (2011). Progastrin Stimulates Colonic Myofibroblast Proliferation In Vitro and Its Transgenic Overexpression Increases Colonic Myofibroblast Abundance In Vivo. Gastroenterology, 140(5), S-106. doi:10.1016/s0016-5085(11)60429-0DOI: 10.1016/s0016-5085(11)60429-0
The Effects of Host, Environmental and Bacterial Factors on Development of Gastric Preneoplastic Pathology (Journal article)
Murugesan, S. V., Tiszlavicz, L., Steele, I., Farragher, T., Moore, A. R., Varro, A., & Pritchard, D. M. (2011). The Effects of Host, Environmental and Bacterial Factors on Development of Gastric Preneoplastic Pathology. Gastroenterology, 140(5). doi:10.1016/s0016-5085(11)62805-9DOI: 10.1016/s0016-5085(11)62805-9
Bak Deficiency Alters Gastric Epithelial Homeostasis and Modulates the Consequences of Helicobacter fells Infection <i>In Vivo</i> (Journal article)
Duckworth, C. A., Abuderman, A. A., Burkitt, M. D., & Pritchard, D. M. (2011). Bak Deficiency Alters Gastric Epithelial Homeostasis and Modulates the Consequences of Helicobacter fells Infection <i>In Vivo</i>. GASTROENTEROLOGY, 140(5), S824. Retrieved from https://www.webofscience.com/
Zollinger-Ellison Syndrome: Still a Diagnostic Challenge in the 21st Century? (Journal article)
Pritchard, D. M. (2011). Zollinger-Ellison Syndrome: Still a Diagnostic Challenge in the 21st Century?. GASTROENTEROLOGY, 140(5), 1380-1383. doi:10.1053/j.gastro.2011.03.026DOI: 10.1053/j.gastro.2011.03.026
2010
Gastrin regulates the urokinase plasminogen activator system (Journal article)
Norsett, K. G., Steele, I., Rainbow, L., Murugesam, S. V. M., Duval, C., Kenny, S., . . . Varro, A. (2010). Gastrin regulates the urokinase plasminogen activator system. REGULATORY PEPTIDES, 164(1), 29. doi:10.1016/j.regpep.2010.07.067DOI: 10.1016/j.regpep.2010.07.067
The management of gastric polyps (Journal article)
Goddard, A. F., Badreldin, R., Pritchard, D. M., Walker, M. M., & Warren, B. (2010). The management of gastric polyps. GUT, 59(9), 1270-1276. doi:10.1136/gut.2009.182089DOI: 10.1136/gut.2009.182089
587 EGFR Inhibitor Reduces Helicobacter-Induced Upregulation of Gastric Activation-Induced Cytidine Deaminase in the Murine INS-GAS Cancer Model (Journal article)
Duval, C., Pritchard, D. M., Abuderman, A., Varro, A., Robinson, P. A., & Crabtree, J. E. (2010). 587 EGFR Inhibitor Reduces Helicobacter-Induced Upregulation of Gastric Activation-Induced Cytidine Deaminase in the Murine INS-GAS Cancer Model. Gastroenterology, 138(5), S-84. doi:10.1016/s0016-5085(10)60382-4DOI: 10.1016/s0016-5085(10)60382-4
S1693 Progrp-Derived Peptides are Present in Human Colorectal Cancer Cells and Stimulate Proliferation In Vitro and in the Murine Colonic Mucosa In Vivo (Journal article)
Patel, O., Clyde, D., Chang, M., Nordlund, M. S., Pritchard, D. M., Shulkes, A., & Baldwin, G. S. (2010). S1693 Progrp-Derived Peptides are Present in Human Colorectal Cancer Cells and Stimulate Proliferation In Vitro and in the Murine Colonic Mucosa In Vivo. Gastroenterology, 138(5), S-255. doi:10.1016/s0016-5085(10)61163-8DOI: 10.1016/s0016-5085(10)61163-8
Conditional Deletion of IκB-Kinase-β Accelerates <i>Helicobacter</i>-Dependent Gastric Apoptosis, Proliferation, and Preneoplasia (Journal article)
Shibata, W., Takaishi, S., Muthupalani, S., Pritchard, D. M., Whary, M. T., Rogers, A. B., . . . Wang, T. C. (2010). Conditional Deletion of IκB-Kinase-β Accelerates <i>Helicobacter</i>-Dependent Gastric Apoptosis, Proliferation, and Preneoplasia. GASTROENTEROLOGY, 138(3), 1022-U295. doi:10.1053/j.gastro.2009.11.054DOI: 10.1053/j.gastro.2009.11.054
2009
Review article: cellular and molecular mechanisms of NSAID-induced peptic ulcers (Journal article)
Musumba, C., Pritchard, D. M., & Pirmohamed, M. (2009). Review article: cellular and molecular mechanisms of NSAID-induced peptic ulcers. ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 30(6), 517-531. doi:10.1111/j.1365-2036.2009.04086.xDOI: 10.1111/j.1365-2036.2009.04086.x
Inactivating cholecystokinin-2 receptor inhibits progastrin-dependent colonic crypt fission, proliferation, and colorectal cancer in mice (Journal article)
Jin, G., Ramanathan, V., Quante, M., Baik, G. H., Yang, X., Wang, S. S. W., . . . Wang, T. C. (2009). Inactivating cholecystokinin-2 receptor inhibits progastrin-dependent colonic crypt fission, proliferation, and colorectal cancer in mice. JOURNAL OF CLINICAL INVESTIGATION, 119(9), 2691-2701. doi:10.1172/JCI38918DOI: 10.1172/JCI38918
Review article: strategies to determine whether hypergastrinaemia is due to Zollinger-Ellison syndrome rather than a more common benign cause (Journal article)
Murugesan, S. V. M., Varro, A., & Pritchard, D. M. (2009). Review article: strategies to determine whether hypergastrinaemia is due to Zollinger-Ellison syndrome rather than a more common benign cause. ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 29(10), 1055-1068. doi:10.1111/j.1365-2036.2009.03976.xDOI: 10.1111/j.1365-2036.2009.03976.x
T1633 Gastric Helicobacter Infection Induces Iron Deficiency in the INS-GAS Mouse (Journal article)
Boxall, S., Pritchard, D. M., Abuderman, A., Wang, T. C., Varro, A., & Crabtree, J. E. (2009). T1633 Gastric Helicobacter Infection Induces Iron Deficiency in the INS-GAS Mouse. Gastroenterology, 136(5), A-547. doi:10.1016/s0016-5085(09)62513-0DOI: 10.1016/s0016-5085(09)62513-0
KLF4 gene expression is inhibited by the notch signaling pathway that controls goblet cell differentiation in mouse gastrointestinal tract (Journal article)
Zheng, H., Pritchard, D. M., Yang, X., Bennett, E., Liu, G., Liu, C., & Ai, W. (2009). KLF4 gene expression is inhibited by the notch signaling pathway that controls goblet cell differentiation in mouse gastrointestinal tract. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 296(3), G490-G498. doi:10.1152/ajpgi.90393.2008DOI: 10.1152/ajpgi.90393.2008
Importance of gastrin in the pathogenesis and treatment of gastric tumors (Journal article)
Burkitt, M. D., Varro, A., & Pritchard, D. M. (2009). Importance of gastrin in the pathogenesis and treatment of gastric tumors. WORLD JOURNAL OF GASTROENTEROLOGY, 15(1), 1-16. doi:10.3748/wjg.15.1DOI: 10.3748/wjg.15.1
Suppression of Apoptosis, Crypt Hyperplasia, and Altered Differentiation in the Colonic Epithelia of <i>Bak</i>-Null Mice (Journal article)
Duckworth, C. A., & Pritchard, D. M. (2009). Suppression of Apoptosis, Crypt Hyperplasia, and Altered Differentiation in the Colonic Epithelia of <i>Bak</i>-Null Mice. GASTROENTEROLOGY, 136(3), 943-952. doi:10.1053/j.gastro.2008.11.036DOI: 10.1053/j.gastro.2008.11.036
2008
Gastrin increases mcl-1 expression in type I gastric carcinoid tumors and a gastric epithelial cell line that expresses the CCK-2 receptor (Journal article)
Pritchard, D. M., Berry, D., Przemeck, S. M. C., Campbell, F., Edwards, S. W., & Varro, A. (2008). Gastrin increases mcl-1 expression in type I gastric carcinoid tumors and a gastric epithelial cell line that expresses the CCK-2 receptor. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 295(4), G798-G805. doi:10.1152/ajpgi.00015.2008DOI: 10.1152/ajpgi.00015.2008
Increased expression of the urokinase plasminogen activator system by <i>Helicobacter pylori</i> in gastric epithelial cells (Journal article)
Kenny, S., Duval, C., Sammut, S. J., Steele, I., Pritchard, D. M., Atherton, J. C., . . . Varro, A. (2008). Increased expression of the urokinase plasminogen activator system by <i>Helicobacter pylori</i> in gastric epithelial cells. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 295(3), G431-G441. doi:10.1152/ajpgi.90283.2008DOI: 10.1152/ajpgi.90283.2008
606 KLF4 Is a Downstream Target of the Notch Signaling Pathway That Controls Goblet Cell Differentiation in the Mouse GI Tract (Journal article)
Yang, X., Pritchard, D. M., Takaishi, S., Tu, S., Marrache, F., Gordon, S. A., . . . Ai, W. (2008). 606 KLF4 Is a Downstream Target of the Notch Signaling Pathway That Controls Goblet Cell Differentiation in the Mouse GI Tract. Gastroenterology, 134(4), A-84. doi:10.1016/s0016-5085(08)60396-0DOI: 10.1016/s0016-5085(08)60396-0
812 Inactivation of Cholecystokinin-2 Receptor Inhibits Progastrin-Dependent Colonic Proliferation and Colorectal Cancer in Mice (Journal article)
Jin, G., Dubeykovskiy, A. N., Pritchard, D. M., Betz, K. S., Varro, A., & Wang, T. C. (2008). 812 Inactivation of Cholecystokinin-2 Receptor Inhibits Progastrin-Dependent Colonic Proliferation and Colorectal Cancer in Mice. Gastroenterology, 134(4), A-115. doi:10.1016/s0016-5085(08)60537-5DOI: 10.1016/s0016-5085(08)60537-5
Assessment of the efficacy and toxicity of <SUP>131</SUP>I-metaiodobenzylguanidine therapy for metastatic neuroendocrine tumours (Journal article)
Nwosu, A. C., Jones, L., Vora, J., Poston, G. J., Vinjamuri, S., & Pritchard, D. M. (2008). Assessment of the efficacy and toxicity of <SUP>131</SUP>I-metaiodobenzylguanidine therapy for metastatic neuroendocrine tumours. BRITISH JOURNAL OF CANCER, 98(6), 1053-1058. doi:10.1038/sj.bjc.6604273DOI: 10.1038/sj.bjc.6604273
Hypergastrinemia increases gastric epithelial susceptibility to apoptosis (Journal article)
Przemeck, S. M. C., Varro, A., Berry, D., Steele, I., Wang, T. C., Dockray, G. J., & Pritchard, D. M. (2008). Hypergastrinemia increases gastric epithelial susceptibility to apoptosis. REGULATORY PEPTIDES, 146(1-3), 147-156. doi:10.1016/j.regpep.2007.09.002DOI: 10.1016/j.regpep.2007.09.002
Hypergastrinemia increases gastric epithelial susceptibility to apoptosis (Journal article)
Przemeck, S. M. C., Varro, A., Berry, D., Steele, I., Wang, T. C., Dockray, G. J., & Pritchard, D. M. (2008). Hypergastrinemia increases gastric epithelial susceptibility to apoptosis. Regulatory Peptides, 146(1-3), 147-156. doi:10.1016/j.regpep.2007.09.002DOI: 10.1016/j.regpep.2007.09.002
Altered gastric corpus expression of tissue inhibitors of metalloproteinases in human and murine <i>Helicobacter</i> infection (Journal article)
Bodger, K., Ahmed, S., Pazmany, L., Pritchard, D. M., Micheal, A., Khan, A. L., . . . Varro, A. (2008). Altered gastric corpus expression of tissue inhibitors of metalloproteinases in human and murine <i>Helicobacter</i> infection. JOURNAL OF CLINICAL PATHOLOGY, 61(1), 72-78. doi:10.1136/jcp.2007.048058DOI: 10.1136/jcp.2007.048058
Altered gastric corpus expression of tissue inhibitors of metalloproteinases in human and murine Helicobacter infection (Journal article)
Bodger, K., Ahmed, S., Pazmany, L., Pritchard, D. M., Micheal, A., Khan, A. L., . . . Varro, A. (n.d.). Altered gastric corpus expression of tissue inhibitors of metalloproteinases in human and murine Helicobacter infection. Journal of Clinical Pathology, 61(1), 72-78. doi:10.1136/jcp.2007.048058DOI: 10.1136/jcp.2007.048058
2007
<i>Helicobacter</i> and gastrin stimulate Reg1 expression in gastric epithelial cells through distinct promoter elements (Journal article)
Steele, I. A., Dimaline, R., Pritchard, D. M., Peek, R. M. J., Wang, T. C., Dockray, G. J., & Varro, A. (2007). <i>Helicobacter</i> and gastrin stimulate Reg1 expression in gastric epithelial cells through distinct promoter elements. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 293(1), G347-G354. doi:10.1152/ajpgi.00076.2007DOI: 10.1152/ajpgi.00076.2007
Pathogenesis of gastrinomas associated with multiple endocrine neoplasia type 1 (Journal article)
Pritchard, D. M. (2007). Pathogenesis of gastrinomas associated with multiple endocrine neoplasia type 1. GUT, 56(5), 606-607. doi:10.1136/gut.2006.113985DOI: 10.1136/gut.2006.113985
Increased gastric expression of MMP-7 in hypergastrinemia and significance for epithelial-mesenchymal signaling (Journal article)
Varro, A., Kenny, S., Hemers, E., McCaig, C., Przemeck, S., Wang, T. C., . . . Pritchard, D. M. (2007). Increased gastric expression of MMP-7 in hypergastrinemia and significance for epithelial-mesenchymal signaling. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 292(4), G1133-G1140. doi:10.1152/ajpgi.00526.2006DOI: 10.1152/ajpgi.00526.2006
Radiation-induced gastric epithelial apoptosis occurs in the proliferative zone and is regulated by p53, bak, bax, and bcl-2 (Journal article)
Przemeck, S. M. C., Duckworth, C. A., & Pritchard, D. M. (2007). Radiation-induced gastric epithelial apoptosis occurs in the proliferative zone and is regulated by p53, bak, bax, and bcl-2. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 292(2), G620-G627. doi:10.1152/ajpgi.00391.2006DOI: 10.1152/ajpgi.00391.2006
Bak-null mice demonstrate suppression of epithelial apoptosis, crypt hyperplasia and altered differentiation in the colon, and are more susceptible to colonic carcinogenesis (Journal article)
Duckworth, C. A., & Pritchard, D. M. (2007). Bak-null mice demonstrate suppression of epithelial apoptosis, crypt hyperplasia and altered differentiation in the colon, and are more susceptible to colonic carcinogenesis. GASTROENTEROLOGY, 132(4), A154. Retrieved from https://www.webofscience.com/
2006
<i>Helicobacter pylori</i> and gastric cancer (Journal article)
Pritchard, D. M., & Crabtree, J. E. (2006). <i>Helicobacter pylori</i> and gastric cancer. CURRENT OPINION IN GASTROENTEROLOGY, 22(6), 620-625. doi:10.1097/01.mog.0000245539.50765.f6DOI: 10.1097/01.mog.0000245539.50765.f6
Review article: pathogenesis and management of gastric carcinoid tumours (Journal article)
Burkitt, M. D., & Pritchard, D. M. (2006). Review article: pathogenesis and management of gastric carcinoid tumours. ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 24(9), 1305-1320. doi:10.1111/j.1365-2036.2006.03130.xDOI: 10.1111/j.1365-2036.2006.03130.x
Characterization of epithelial cell shedding from human small intestine (Journal article)
Bullen, T. F., Forrest, S., Campbell, F., Dodson, A. R., Hershman, M. J., Pritchard, D. M., . . . Watson, A. J. M. (2006). Characterization of epithelial cell shedding from human small intestine. LABORATORY INVESTIGATION, 86(10), 1052-1063. doi:10.1038/labinvest.3700464DOI: 10.1038/labinvest.3700464
Gastrin-induced apoptosis contributes to carcinogenesis in the stomach (Journal article)
Cui, G., Takaishi, S., Ai, W., Betz, K. S., Florholmen, J., Koh, T. J., . . . Wang, T. C. (2006). Gastrin-induced apoptosis contributes to carcinogenesis in the stomach. LABORATORY INVESTIGATION, 86(10), 1037-1051. doi:10.1038/labinvest.3700462DOI: 10.1038/labinvest.3700462
Gastrin and members of the bcl-2 family regulate gastric epithelial apoptosis in vivo (Journal article)
Przemeck, S., Duckworth, C. A., Varro, A., Pritchard, D., & Pritchard, M. (2006). Gastrin and members of the bcl-2 family regulate gastric epithelial apoptosis in vivo. GUT, 55, A61. Retrieved from https://www.webofscience.com/
Gastrin increases MCL-1 expression in AGS<sub>GR</sub> gastric epithelial cells to cause supression of apoptosis (Conference Paper)
Przemeck, S., Varro, A., & Pritchard, D. M. (2006). Gastrin increases MCL-1 expression in AGS<sub>GR</sub> gastric epithelial cells to cause supression of apoptosis. In GUT Vol. 55 (pp. A27). Retrieved from https://www.webofscience.com/
Gastrin increases murine intestinal crypt regeneration following injury (Journal article)
Ottewell, P. D., Duckworth, C. A., Varro, A., Dimaline, R., Wang, T. C., Watson, A. J. M., . . . Pritchard, D. M. (2006). Gastrin increases murine intestinal crypt regeneration following injury. GASTROENTEROLOGY, 130(4), 1169-1180. doi:10.1053/j.gastro.2005.12.033DOI: 10.1053/j.gastro.2005.12.033
Suppression of colonic epithelial apoptosis and crypt hyperplasia occurs in <i>bak</i>-null mice (Journal article)
Duckworth, C. A., & Pritchard, D. M. (2006). Suppression of colonic epithelial apoptosis and crypt hyperplasia occurs in <i>bak</i>-null mice. GUT, 55, A9. Retrieved from https://www.webofscience.com/
The role of matrix metalloprotease-7 in redefining the gastric micro-environment in response to gastrin and <i>H pylori</i> (Conference Paper)
Varro, A., Pritchard, D. M., McCaig, C., Duval, C., Campbell, F., Ahmed, S., . . . Kerrigan, D. D. (2006). The role of matrix metalloprotease-7 in redefining the gastric micro-environment in response to gastrin and <i>H pylori</i>. In GUT Vol. 55 (pp. A114). Retrieved from https://www.webofscience.com/
The role of matrix metalloproteinase-7 in redefining the gastric microenvironment in response to <i>Helicobacter pylori</i> (Journal article)
McCaig, C., Duval, C., Hemers, E., Steele, I., Pritchard, D. M., Przemeck, S., . . . Varro, A. (2006). The role of matrix metalloproteinase-7 in redefining the gastric microenvironment in response to <i>Helicobacter pylori</i>. GASTROENTEROLOGY, 130(6), 1754-1763. doi:10.1053/j.gastro.2006.02.031DOI: 10.1053/j.gastro.2006.02.031
2005
Models of gastric cancer (Journal article)
Pritchard, D. M. (2005). Models of gastric cancer. Drug Discovery Today: Disease Models, 2(1), 21-26. doi:10.1016/j.ddmod.2005.05.001DOI: 10.1016/j.ddmod.2005.05.001
COOH-terminal 26-amino acid residues of progastrin are sufficient for stimulation of mitosis in murine colonic epithelium in vivo (Journal article)
Ottewell, P. D., Varro, A., Dockray, G. J., Kirton, C. M., Watson, A. J. M., Wang, T. C., . . . Pritchard, D. M. (2005). COOH-terminal 26-amino acid residues of progastrin are sufficient for stimulation of mitosis in murine colonic epithelium in vivo. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 288(3), G541-G549. doi:10.1152/ajpgi.00268.2004DOI: 10.1152/ajpgi.00268.2004
Gastrin induces MDM-2 and suppresses p53 expression in AGS<sub>GR</sub> cells, resulting in resistance to DNA damage induced apoptosis (Journal article)
Przemeck, S. M. C., Watson, A. J., Varro, A., & Pritchard, D. M. (2005). Gastrin induces MDM-2 and suppresses p53 expression in AGS<sub>GR</sub> cells, resulting in resistance to DNA damage induced apoptosis. GUT, 54, A87-A88. Retrieved from https://www.webofscience.com/
Gastrin induces mdm-2 and suppresses p53 protein expression in Ags-GR cells, resulting in resistance to DNA damage induced apoptosis (Journal article)
Przemeck, S. M., Watson, A. J., Varro, A., & Pritichard, D. M. (2005). Gastrin induces mdm-2 and suppresses p53 protein expression in Ags-GR cells, resulting in resistance to DNA damage induced apoptosis. Gastroenterology, 128(4 Supp), A-141.
Hypergastrinaemia reduces the severity of dextran sulphate sodium induced colitis and 5-fluorouracil induced intestinal mucositis in mice. (Journal article)
Duckworth, C. A., Ottewell, P. D., Varro, A., Dimaline, R., & Pritchard, D. M. (2005). Hypergastrinaemia reduces the severity of dextran sulphate sodium induced colitis and 5-fluorouracil induced intestinal mucositis in mice.. GASTROENTEROLOGY, 128(4), A203. Retrieved from https://www.webofscience.com/
Hypergastrinaemia reduces the severity of dextran sulphate sodium induced colitis and 5-fluorouracil induced mucositis in mice (Journal article)
Duckworth, C. A., Ottewell, P. D., Dimaline, R., Varro, A., & Pritchard, D. M. (2005). Hypergastrinaemia reduces the severity of dextran sulphate sodium induced colitis and 5-fluorouracil induced mucositis in mice. GUT, 54, A98. Retrieved from https://www.webofscience.com/
Radiation induces gastrin-CCK<sub>B</sub> receptor expression in IEC-6 and IEC-18 intestinal epithelial cells (Journal article)
Ottewell, P. D., Watson, A. J., Varro, A., & Pritchard, D. M. (2005). Radiation induces gastrin-CCK<sub>B</sub> receptor expression in IEC-6 and IEC-18 intestinal epithelial cells. GUT, 54, A88. Retrieved from https://www.webofscience.com/
Radiation induces p53 dependent apoptosis in the proliferative zone of mouse gastric epithelium (Journal article)
Przemeck, S. M. C., Ottewell, P. D., Watson, A. J. M., & Pritchard, D. M. (2005). Radiation induces p53 dependent apoptosis in the proliferative zone of mouse gastric epithelium. GUT, 54, A88. Retrieved from https://www.webofscience.com/
Shedding of human intestinal epithelial cells results in gaps in the epithelial monolayer (Journal article)
Bullen, T. F., Campbell, F., Pritchard, D. M., Hershman, M. J., & Watson, A. J. M. (2005). Shedding of human intestinal epithelial cells results in gaps in the epithelial monolayer. GUT, 54, A25. Retrieved from https://www.webofscience.com/
Th1 cytokines, but not gastrin increase <i>Helicobacter pylori</i> induced apoptosis in short term primary cultures of murine gastric glands (Journal article)
Przemeck, M. C., Watson, A. J., Varro, A., & Pritchard, D. M. (2005). Th1 cytokines, but not gastrin increase <i>Helicobacter pylori</i> induced apoptosis in short term primary cultures of murine gastric glands. GUT, 54, A61. Retrieved from https://www.webofscience.com/
2004
Review article: how useful are the rodent animal models of gastric adenocarcinoma? (Journal article)
Pritchard, D. M., & Przemeck, S. M. C. (2004). Review article: how useful are the rodent animal models of gastric adenocarcinoma?. ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 19(8), 841-859. doi:10.1111/j.1365-2036.2004.01911.xDOI: 10.1111/j.1365-2036.2004.01911.x
<i>Helicobacter pylori</i> induces plasminogen activator inhibitor 2 in gastric epithelial cells through nuclear factor-κB and RhoA:: Implications for invasion and apoptosis (Journal article)
Varro, A., Noble, P. J. M., Pritchard, D. M., Kennedy, S., Hart, C. A., Dimaline, R., & Dockray, G. J. (2004). <i>Helicobacter pylori</i> induces plasminogen activator inhibitor 2 in gastric epithelial cells through nuclear factor-κB and RhoA:: Implications for invasion and apoptosis. CANCER RESEARCH, 64(5), 1695-1702. doi:10.1158/0008-5472.CAN-03-2399DOI: 10.1158/0008-5472.CAN-03-2399
Helicobacter pylori induces plasminogen activator inhibitor 2 in gastric epithelial cells through nuclear factor-kappaB and RhoA: implications for invasion and apoptosis (Journal article)
Varro, A., Noble, P. J., Pritchard, D. M., Kennedy, S., Hart, C. A., Dimaline, R., & Dockray, G. J. (2004). Helicobacter pylori induces plasminogen activator inhibitor 2 in gastric epithelial cells through nuclear factor-kappaB and RhoA: implications for invasion and apoptosis. Cancer Res, 64(5), 1695-1702. Retrieved from http://www.ncbi.nlm.nih.gov/
Helicobacter pylori induces plasminogen activator inhibitor 2 in gastric epithelial cells through nuclear factor-kappaB and RhoA: implications for invasion and apoptosis (Journal article)
Varro, A., Noble, P. J., Pritchard, D. M., Kennedy, S., Hart, C. A., Dimaline, R., & Dockray, G. J. (2004). Helicobacter pylori induces plasminogen activator inhibitor 2 in gastric epithelial cells through nuclear factor-kappaB and RhoA: implications for invasion and apoptosis. Cancer Res, 64(5), 1695-1702. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/14996729
MMP-7 acts as a signal from epithelial cells to myofibroblasts in gastric carcinoid tumours (Conference Paper)
Varro, A., Hemers, E., & Pritchard, D. M. (2004). MMP-7 acts as a signal from epithelial cells to myofibroblasts in gastric carcinoid tumours. In BRITISH JOURNAL OF CANCER Vol. 91 (pp. S10). Retrieved from https://www.webofscience.com/
New role for gastrin in regulating epithelial-mesenchymal signalling via MMP-7 in gastric carcinoid tumours (Conference Paper)
Hemers, E., Pritchard, D. M., Campbell, F., Ahmed, S., Bodger, K., Kerrigan, D. D., . . . Varro, A. (2004). New role for gastrin in regulating epithelial-mesenchymal signalling via MMP-7 in gastric carcinoid tumours. In REGULATORY PEPTIDES Vol. 122 (pp. 45). Retrieved from https://www.webofscience.com/
Regulation of plasminogen activator inhibitor 2 (PAI-2) by <i>Helicobacter pylori</i>:: Role in invasion and in apoptosis (Conference Paper)
Varro, A., Noble, P. J. M., Pritchard, D. M., Kennedy, S., Dimaline, R., Hart, C. A., & Dockray, G. J. (2004). Regulation of plasminogen activator inhibitor 2 (PAI-2) by <i>Helicobacter pylori</i>:: Role in invasion and in apoptosis. In GUT Vol. 53 (pp. A15). Retrieved from https://www.webofscience.com/
2003
Can proton pump inhibitors be blamed for the rising incidence of esophageal cancer? (Journal article)
Younes, M. (2003). Can proton pump inhibitors be blamed for the rising incidence of esophageal cancer?. GASTROENTEROLOGY, 125(6), 1912. doi:10.1053/j.gastro.2003.04.014DOI: 10.1053/j.gastro.2003.04.014
Gastrin-induced hyperproliferation in Barrett's esophagus - Reply (Journal article)
Haigh, C. R., Kirton, C. M., Pritchard, D. M., Varro, A., Dimaline, R., Attwood, S. E. A., . . . Jankowski, J. A. (2003). Gastrin-induced hyperproliferation in Barrett's esophagus - Reply. GASTROENTEROLOGY, 125(6), 1921-1922. doi:10.1053/j.gastro.2003.10.036DOI: 10.1053/j.gastro.2003.10.036
Stimulation of matrix metalloproteinase-7 (MMP-7) by Helicobacter pylori in gastric epithelial cells: role in epithelial cell migration (Journal article)
Wroblewski, L. E., Noble, P. -J., Pagliocca, A., Pritchard, D. M., Hart, C. T., & Varro, A. (2003). Stimulation of matrix metalloproteinase-7 (MMP-7) by Helicobacter pylori in gastric epithelial cells: role in epithelial cell migration. Gastroenterology, 124(4), A6. doi:10.1016/s0016-5085(03)80030-6DOI: 10.1016/s0016-5085(03)80030-6
Gastrin induces proliferation in Barrett's metaplasia through activation of the CCK<sub>2</sub> receptor (Journal article)
Haigh, C. R., Attwood, S. E. A., Thompson, D. G., Jankowski, J. A., Kirton, C. M., Pritchard, D. M., . . . Dimaline, R. (2003). Gastrin induces proliferation in Barrett's metaplasia through activation of the CCK<sub>2</sub> receptor. GASTROENTEROLOGY, 124(3), 615-625. doi:10.1053/gast.2003.50091DOI: 10.1053/gast.2003.50091
Can proton pump inhibitors be blamed for the rising incidence of esophageal cancer? Reply (Journal article)
Haigh, C. R., Kirton, C., Pritchard, D. M., Varro, A., Dimaline, R., Attwood, S. E. A., . . . Jankowski, J. A. (2003). Can proton pump inhibitors be blamed for the rising incidence of esophageal cancer? Reply. GASTROENTEROLOGY, 125(6), 1912-1913. doi:10.1053/j.gastro.2003.10.031DOI: 10.1053/j.gastro.2003.10.031
Elevated plasma concentrations of amidated gastrin cause increased crypt survival in murine intestinal epithelia after γ radiation (Journal article)
Ottewell, P. D., Watson, A. J. M., Wang, T. C., Varro, A., Dockray, G. J., & Pritchard, D. M. (2003). Elevated plasma concentrations of amidated gastrin cause increased crypt survival in murine intestinal epithelia after γ radiation. GUT, 52, A8. Retrieved from https://www.webofscience.com/
Gastrin-induced hyperproliferation in Barrett's esophagus (Journal article)
Fitzgerald, R. C., & Abdalla, S. (2003). Gastrin-induced hyperproliferation in Barrett's esophagus. GASTROENTEROLOGY, 125(6), 1921. doi:10.1053/j.gastro.2003.05.017DOI: 10.1053/j.gastro.2003.05.017
Progastrin stimulates murine colonic epithelial mitosis after DNA damage. (Journal article)
Ottewell, P. D., Watson, A. J., Wang, T. C., Varro, A., Dockray, G. J., & Pritchard, D. M. (2003). Progastrin stimulates murine colonic epithelial mitosis after DNA damage.. Gastroenterology, 124(5), 1348-1357. doi:10.1016/S0016-5085(03)00288-9DOI: 10.1016/S0016-5085(03)00288-9
Stimulation of matrix metalloproteinase-7 (MMP-7) by <i>Helicobacter pylori</i> in gastric epithelial cells:: Role in epithelial cell migration (Conference Paper)
Varro, A., Wroblewski, L. E., Pagliocca, A., Pritchard, D. M., Noble, P. J. M., & Hart, C. A. (2003). Stimulation of matrix metalloproteinase-7 (MMP-7) by <i>Helicobacter pylori</i> in gastric epithelial cells:: Role in epithelial cell migration. In GUT Vol. 52 (pp. A53). Retrieved from https://www.webofscience.com/
2002
Gastrin-stimulated gastric epithelial cell invasion: the role and mechanism of increased matrix metalloproteinase 9 expression (Journal article)
Wroblewski, L. E., Pritchard, D. M., Carter, S., & Varro, A. (2002). Gastrin-stimulated gastric epithelial cell invasion: the role and mechanism of increased matrix metalloproteinase 9 expression. BIOCHEMICAL JOURNAL, 365, 873-879. doi:10.1042/BJ20020068DOI: 10.1042/BJ20020068
Progastrin Stimulates Murine Colonic Epithelial Mitosis after Dna Damage (Journal article)
Pritchard, D. M., Ottewell, P. D., Watson, A. J. M., Wang, T. C., & Dockray, G. J. (2002). Progastrin Stimulates Murine Colonic Epithelial Mitosis after Dna Damage. Clinical Science, 103(s47), 43P. doi:10.1042/cs103043pDOI: 10.1042/cs103043p
Amidated gastrin induces proliferation via the cholecystokinin type 2 (CCK<sub>2</sub>) receptor in Barrett's oesophagus (Conference Paper)
Haigh, C. R., Attwood, S. E. A., Thompson, D. G., Kirton, C. M., Pritchard, D. M., Varro, A., & Dimaline, R. (2002). Amidated gastrin induces proliferation via the cholecystokinin type 2 (CCK<sub>2</sub>) receptor in Barrett's oesophagus. In JOURNAL OF PHYSIOLOGY-LONDON Vol. 543 (pp. 50P). Retrieved from https://www.webofscience.com/
Progastrin stimulates murine colonic epithelial mitosis after DNA damage (Journal article)
Ottewell, P. D., Watson, A. J. M., Wang, T. C., Dockray, G. J., & Pritchard, D. M. (2002). Progastrin stimulates murine colonic epithelial mitosis after DNA damage. GUT, 50, A93. Retrieved from https://www.webofscience.com/
2000
Bcl-w is an important determinant of damage-induced apoptosis in epithelia of small and large intestine (Journal article)
Pritchard, D. M., Print, C., O'Reilly, L., Adams, J. M., Potten, C. S., & Hickman, J. A. (2000). Bcl-w is an important determinant of damage-induced apoptosis in epithelia of small and large intestine. ONCOGENE, 19(34), 3955-3959. doi:10.1038/sj.onc.1203729DOI: 10.1038/sj.onc.1203729
BCL-W expression is an important determinant of damage-induced apoptosis in murine small and large intestinal epithelium in vivo (Journal article)
Pritchard, D. M., Print, C., Adams, J. M., Potten, C. S., & Hickman, J. A. (2000). BCL-W expression is an important determinant of damage-induced apoptosis in murine small and large intestinal epithelium in vivo. Gastroenterology, 118(4), A538. doi:10.1016/s0016-5085(00)84284-5DOI: 10.1016/s0016-5085(00)84284-5
New directions in the treatment of colorectal cancer: a look to the future (Journal article)
Sobrero, A., Kerr, D., Glimelius, B., Van Cutsem, E., Milano, G., Pritchard, D. M., . . . Aapro, M. (2000). New directions in the treatment of colorectal cancer: a look to the future. EUROPEAN JOURNAL OF CANCER, 36(5), 559-566. doi:10.1016/S0959-8049(99)00314-7DOI: 10.1016/S0959-8049(99)00314-7
Balb/c mice as a preclinical model for raltitrexed-induced gastrointestinal toxicity (Journal article)
Clarke, S. J., Farrugia, D. C., Aherne, G. W., Pritchard, D. M., Benstead, J., & Jackman, A. L. (2000). Balb/c mice as a preclinical model for raltitrexed-induced gastrointestinal toxicity. CLINICAL CANCER RESEARCH, 6(1), 285-296. Retrieved from https://www.webofscience.com/
Lessons from genetically engineered animal models VII. Apoptosis in intestinal epithelium: Lessons from transgenic and knockout mice (Journal article)
Watson, A. J. M., & Pritchard, D. M. (2000). Lessons from genetically engineered animal models VII. Apoptosis in intestinal epithelium: Lessons from transgenic and knockout mice. American Journal of Physiology - Gastrointestinal and Liver Physiology, 278(1 41-1). doi:10.1152/ajpgi.2000.278.1.g1DOI: 10.1152/ajpgi.2000.278.1.g1
Lessons from genetically engineered animal models VII. Apoptosis in intestinal epithelium: lessons from transgenic and knockout mice (Journal article)
Watson, A. J. M., & Pritchard, D. M. (2000). Lessons from genetically engineered animal models VII. Apoptosis in intestinal epithelium: lessons from transgenic and knockout mice. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 278(1), G1-G5. doi:10.1152/ajpgi.2000.278.1.G1DOI: 10.1152/ajpgi.2000.278.1.G1
The importance of p53-independent apoptosis in the intestinal toxicity induced by raltitrexed (ZD1694, Tomudex): Genetic differences between BALB/c and DBA/2 mice (Journal article)
Pritchard, D. M., Bower, L., Potten, C. S., Jackman, A. L., & Hickman, J. A. (2000). The importance of p53-independent apoptosis in the intestinal toxicity induced by raltitrexed (ZD1694, Tomudex): Genetic differences between BALB/c and DBA/2 mice. CLINICAL CANCER RESEARCH, 6(11), 4389-4395. Retrieved from https://www.webofscience.com/
1999
Damage-induced apoptosis in intestinal epithelia from <i>bcl</i>-2-null and <i>bax</i>-null mice:: investigations of the mechanistic determinants of epithelial apoptosis <i>in vivo</i> (Journal article)
Pritchard, D. M., Potten, C. S., Korsmeyer, S. J., Roberts, S., & Hickman, J. A. (1999). Damage-induced apoptosis in intestinal epithelia from <i>bcl</i>-2-null and <i>bax</i>-null mice:: investigations of the mechanistic determinants of epithelial apoptosis <i>in vivo</i>. ONCOGENE, 18(51), 7287-7293. doi:10.1038/sj.onc.1203150DOI: 10.1038/sj.onc.1203150
Role of Bcl-2 Family Members in Homeostasis, in Toxicology in Normal Intestine, and for Prognosis of Colonic Carcinomas (Chapter)
Pritchard, D. M. (1999). Role of Bcl-2 Family Members in Homeostasis, in Toxicology in Normal Intestine, and for Prognosis of Colonic Carcinomas. In Apoptosis and Cancer Chemotherapy (pp. 275-290). Humana Press. doi:10.1007/978-1-59259-720-8_18DOI: 10.1007/978-1-59259-720-8_18
1998
Chemically-induced apoptosis: p21 and p53 as determinants of enterotoxin activity (Journal article)
Pritchard, D. M., Jackman, A., Potten, C. S., & Hickman, J. A. (1998). Chemically-induced apoptosis: p21 and p53 as determinants of enterotoxin activity. TOXICOLOGY LETTERS, 103, 19-27. doi:10.1016/S0378-4274(98)00273-2DOI: 10.1016/S0378-4274(98)00273-2
The relationships between p53-dependent apoptosis, inhibition of proliferation, and 5-fluorouracil-induced histopathology in murine intestinal epithelia (Journal article)
Pritchard, D. M., Potten, C. S., & Hickman, J. A. (1998). The relationships between p53-dependent apoptosis, inhibition of proliferation, and 5-fluorouracil-induced histopathology in murine intestinal epithelia. CANCER RESEARCH, 58(23), 5453-5465. Retrieved from https://www.webofscience.com/
Radiation-induced p53 and p21<SUP>WAF-1/CIP1</SUP> expression in the murine intestinal epithelium -: Apoptosis and cell cycle arrest (Journal article)
Wilson, J. W., Pritchard, D. M., Hickman, J. A., & Potten, C. S. (1998). Radiation-induced p53 and p21<SUP>WAF-1/CIP1</SUP> expression in the murine intestinal epithelium -: Apoptosis and cell cycle arrest. AMERICAN JOURNAL OF PATHOLOGY, 153(3), 899-909. doi:10.1016/S0002-9440(10)65631-3DOI: 10.1016/S0002-9440(10)65631-3
1997
The intestinal epithelial stem cell: the mucosal governor (Journal article)
Potten, C. S., Booth, C., & Pritchard, D. M. (1997). The intestinal epithelial stem cell: the mucosal governor. INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY, 78(4), 219-243. doi:10.1046/j.1365-2613.1997.280362.xDOI: 10.1046/j.1365-2613.1997.280362.x
Inhibition by uridine but not thymidine of p53-dependent intestinal apoptosis initiated by 5-fluorouracil: Evidence for the involvement of RNA perturbation (Journal article)
Pritchard, D. M., Watson, A. J. M., Potten, C. S., Jackman, A. L., & Hickman, J. A. (1997). Inhibition by uridine but not thymidine of p53-dependent intestinal apoptosis initiated by 5-fluorouracil: Evidence for the involvement of RNA perturbation. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 94(5), 1795-1799. doi:10.1073/pnas.94.5.1795DOI: 10.1073/pnas.94.5.1795
1996
Apoptosis and gastrointestinal pharmacology (Journal article)
Pritchard, D. M., & Watson, A. J. M. (1996). Apoptosis and gastrointestinal pharmacology. PHARMACOLOGY & THERAPEUTICS, 72(2), 149-169. doi:10.1016/S0163-7258(96)00102-7DOI: 10.1016/S0163-7258(96)00102-7
