Research
Research groups
Research grants
Tissue bank - development of a process of tissue bio-banking and transfer of urological / hepatobilary specimens for academic unit
THE CLATTERBRIDGE CANCER CENTRE NHS FOUNDATION TRUST (UK)
August 2014 - December 2019
A prospective evaluation of a serological screening test for hepatocellular carcinoma; comparison with current standard of care
LIVERPOOL HEALTH PARTNERS (UK)
February 2013 - April 2016
Liver research fund
AINTREE UNIVERSITY HOSPITAL NHS FOUNDATION TRUST (CHARITY) (UK)
April 2012 - March 2013
To evaluate whether cardiopulmonary exercise testing (CPET) offers additional benefit above that of WHO performance status in predicting outcome of patients undergoing palliative chemotherapy for pancreatic cancer
THE CLATTERBRIDGE CANCER CENTRE NHS FOUNDATION TRUST (UK)
January 2015 - December 2021
FSF funding for Senior Trial Co-ordinator
CLATTERBRIDGE CENTRE FOR ONCOLOGY
November 2011 - May 2014
Characterisation of dendritic cell function in the three-dimensional model of urothelial carcinoma in response to soluble CD40L based immunotherapy
THE CLATTERBRIDGE CANCER CENTRE NHS FOUNDATION TRUST (UK)
May 2014 - December 2019
A phase 1b study of pre-operative cisplatin and gemcitabine chemotherapy in patients with Borderline resectable Biliary tract Cancer: BBC-01 study
NORTH WEST CANCER RESEARCH INCORPORATING CLATTERBRIDGE CANCER RESEARCH (UK)
September 2014 - December 2020
Regulation of irinotecan anti-cancer pharmacology by Nrf2 – Implications for current use and potential for improved efficacy
NORTH WEST CANCER RESEARCH FUND
February 2014 - February 2016
Stratification of adjuvant chemotherapeutic response to allow personalised choice of pyrimidine prodrug: based on levels of transporters and enzymes involved in initial metabolism
CANCER RESEARCH UK (UK)
November 2013 - April 2017
ESPAC-5F Four arm, prospective, multicentre, randomised Phase II trial of immediate surgery compared with neoadjuvant chemotherapies and neoadjuvant chemoradiotherapy
CANCER RESEARCH UK (UK)
July 2013 - December 2019
Chair of Oncology support
CLATTERBRIDGE CANCER RESEARCH
July 2011 - March 2017
Applied Cancer Biology Group
CLATTERBRIDGE CANCER RESEARCH
February 2012 - July 2014
Role of monocytes in the metastatic process: identification of novel molecular targets to fight pancreatic cancer
PANCREATIC CANCER RESEARCH FUND (UK)
July 2015 - June 2019
Pembrolizumab IIT Proposal: Cyclophosphamide And PEmbrolizumab in metastatic Renal cell carcinoma (CAPER Trial)
THE CHRISTIE NHS FOUNDATION TRUST (UK)
October 2017 - June 2029
Integrating biomarkers to stratify adjuvant chemotherapy in pancreatic cancer patients
NORTH WEST CANCER RESEARCH INCORPORATING CLATTERBRIDGE CANCER RESEARCH (UK)
January 2019 - August 2022
Treatment of unresectable Locally Advanced Pancreas (LAP) cancer with Percutaneous Irreversible Electroporation (PIE) following initial systemic chemotherapy: a feasibility randomised controlled trial (The LAP-PIE) trial
DEPARTMENT OF HEALTH & SOCIAL CARE (UK)
February 2020 - February 2025
Nanoparticle Interventions for Colorectal Cancer
CANCER RESEARCH UK (UK)
October 2016 - September 2021
A two-arm multi-stage (TAMS) seamless phase II/III randomised trial of nivolumab in combination with TACE for patients with intermediate stage HCC. (TACE-3)
THE CLATTERBRIDGE CANCER CENTRE NHS FOUNDATION TRUST (UK)
March 2018 - September 2026
CCP–CANCER UK: Clinical Characterisation Protocol for Severe Emerging Infections in the UK (CCP-UK) – a prospective companion study for patients with Cancer and COVID-19.
MEDICAL RESEARCH COUNCIL, THE CLATTERBRIDGE CANCER CHARITY (UK)
June 2020 - April 2024
Circulating Tumour DNA Guided Adaptive BRAF and MEK Inhibitor Therapy
THE CHRISTIE NHS FOUNDATION TRUST (UK)
November 2020 - April 2027
CPET OBSERVATIONAL STUDY
ROYAL LIVERPOOL AND BROADGREEN UNIVERSITY HOSPITALS NHS TRUST (UK)
September 2019 - September 2021
A modular, multi-arm, first in human trial to evaluate the safety and tolerability of MDX-124 alone and in combination with anti-cancer treatments, in subjects with locally advanced, unresectable or metastatic solid malignancies
MEDANNEX LIMITED (UK)
June 2022 - April 2027
Proteomic and genomic assessment of hepatopancreaticobiliary cancers
BIONTECH (GERMANY)
September 2020 - August 2029
TARGET trial: Molecular Profiling of Circulating Tumour DNA to Stratify Patients to Early Phase Clinical Trials
THE CHRISTIE NHS FOUNDATION TRUST (UK)
January 2021 - April 2029
PreOperative Brain Irradiation in Glioblastoma (POBIG) (POBIG)
THE CHRISTIE NHS FOUNDATION TRUST (UK)
February 2021 - November 2025
Exploratory analysis of the association between Cox-2 expression and primary resistance to check-point inhibitor therapy for cancer (COX2)
THE CLATTERBRIDGE CANCER CENTRE NHS FOUNDATION TRUST (UK)
May 2020 - January 2026
Interrogating tumour-mediated immunosuppression in peri-hilar cholangiocarcinoma
AMMF THE CHOLANGIOCARCINOMA CHARITY(THE ALAN MOREMENT MEMORIAL FUND)(UK)
August 2023 - August 2026
Assessing Gas6+ neutrophils in the blood of pancreatic cancer patients undergoing chemotherapy to generate evidence for targeting Gas6/AXL signalling in patients
THE CLATTERBRIDGE CANCER CENTRE NHS FOUNDATION TRUST (UK)
September 2023 - August 2025
Liverpool ECMC (LECMC)
CANCER RESEARCH UK (UK), DEPARTMENT OF HEALTH & SOCIAL CARE (UK)
April 2023 - March 2028