Module Specification
The information contained in this module specification was correct at the time of publication but may be subject to change, either during the session because of unforeseen circumstances, or following review of the module at the end of the session. Queries about the module should be directed to the member of staff with responsibility for the module.
Title Clinical, Anatomical and Cellular Basis of Neurological Dysfunction
Code LIFE334
Coordinator Prof JP Quinn
Molecular and Clinical Pharmacology
Jquinn@liverpool.ac.uk
Year CATS Level Semester CATS Value
Session 2016-17 Level 6 FHEQ Second Semester 15

Pre-requisites before taking this module (other modules and/or general educational/academic requirements):
LIFE218; LIFE205 None 

Modules for which this module is a pre-requisite:
 

Co-requisite modules:
 

Linked Modules:
 

Teaching Schedule
  Lectures Seminars Tutorials Lab Practicals Fieldwork Placement Other TOTAL
Study Hours           30
This refers to 10 timetabled 3 hour seminars
30
Timetable (if known)           Seminars include informal discussions. Some or the seminars include research seminars from guest speakers followed by question and answer sections.
  		 
Private Study 120
TOTAL HOURS 150

Assessment
EXAM Duration Timing
(Semester)		 % of
final
mark		 Resit/resubmission
opportunity		 Penalty for late
submission		 Notes
Unseen Written Exam  120  Semester 2  80  Yes    Written examination  
CONTINUOUS Duration Timing
(Semester)		 % of
final
mark		 Resit/resubmission
opportunity		 Penalty for late
submission		 Notes
Coursework  1500 words   Semester 2  20  Yes  Standard UoL penalty applies  Written report Notes (applying to all assessments) The coursework submission date is in week 8. 

Aims

 
 1
 
 
 

2
 

3
 
 
4
 
 
5
 
 
 
 
 
To complement and extend students'' existing knowledge of CNS anatomy and biology to further understanding of the mechanisms which allow the brain function under normal physiological conditions but which can also lead to disease
 
To develop in students an understanding of structure-function relationships in the CNS
 < /span>
To provide students with experience of current clinical and translational research in the neurosciences
 
To introduce students to issues related to mental health and neurological disorders

 
To develop in students the interdisciplinary nature of cutting edge science and how anatomy can inform both surgical and pharmacological intervention in neurological disorders.
 
 

Learning Outcomes

To evaluate the mechanisms underlying the current major problems in mental health and neurological disorders

To critically evaluate the anatomical structures involved in mental health and neurological disorders and the role of neuroimaging

To assess the impact of genomics on our understanding of mental health and neurological disorders

To appraise the application of pharmacological interventions in mental health and neurological disorders


Teaching and Learning Strategies

Seminars - This refers to 10 timetabled 3 hour seminars

Seminars include informal discussions. Some or the seminars include research seminars from guest speakers followed by question and answer sections.

Syllabus
1 


1.     Anatomy of higher cognitive functioning (in particular the temporal lobe)  
2.     Neuroimaging                                       
3.     Genetic predisposition to CNS disorders                   
4.     Stroke                                               
5.     Epilepsy                                    
6.     Multiple sclerosis                                                     
7.     Behaviour     
8.     Schizophrenia                                   
9.     Alzheimer’s disease                                       
10.  Parkinson’s disease                                       
11.  Neurodegenerative diseases (incl. Huntington’s disease and motor neurone disease)       
12.  Depression  

The module will be delivered largely though seminars where i nteraction and discussion with the students is encouraged. Seminars from visiting clinicians and basic scientists at the forefront of current treatment and research will be incorporated to highlight recent advances in selected areas. All teaching material and supplementary teaching material will be available to students on-line through VITAL.
                                                  

Recommended Texts
Reading lists are managed at readinglists.liverpool.ac.uk. Click here to access the reading lists for this module.
Explanation of Reading List:

Principles of Neural Science 4th edition 2000. Kandel, Schwartz and Jessell. Publisher: McGraw-Hill Companies
The lectures will be accompanied by a list of websites and review manuscripts that will be available online and via VITAL.  This reflects the cutting edge nature of the course and our ability to adapt the c ourse annually to reflect breakthroughs and advances in neuroscience.
Books online: Pubmed Bookshelf at NCBI
  http://www.ncbi.nlm.nih.gov/sites/entrez?db=Books&itool=toolbar

School of Life Sciences, University of Liverpool
Crown Street, Liverpool, L69 7ZB
United Kingdom
+44 (0)151 795 5111

Call the department