Module Specification
The information contained in this module specification was correct at the time of publication but may be subject to change, either during the session because of unforeseen circumstances, or following review of the module at the end of the session. Queries about the module should be directed to the member of staff with responsibility for the module.
Title Advanced Genetics Techniques
Code LIFE226
Coordinator Dr KL Hammond
School of Life Sciences
K.Hammond@liverpool.ac.uk
Year CATS Level Semester CATS Value
Session 2016-17 Level 5 FHEQ Second Semester 7.5

Pre-requisites before taking this module (other modules and/or general educational/academic requirements):
LIFE101; LIFE103 None 

Modules for which this module is a pre-requisite:
 

Co-requisite modules:
 

Linked Modules:
 

Teaching Schedule
  Lectures Seminars Tutorials Lab Practicals Fieldwork Placement Other TOTAL
Study Hours 5

     30

   2

3

 40
Timetable (if known) This refers to timetabled lectures
  		    This refers to practical sessions in laboratories, including groupwork
  		  This refers to a poster session held during session 6
This refers to scheduled time for in-course summative assessments
  		 
Private Study 35
TOTAL HOURS 75

Assessment
EXAM Duration Timing
(Semester)		 % of
final
mark		 Resit/resubmission
opportunity		 Penalty for late
submission		 Notes
             
CONTINUOUS Duration Timing
(Semester)		 % of
final
mark		 Resit/resubmission
opportunity		 Penalty for late
submission		 Notes
Practical Assessment  3 hours  Semester 2  40  No reassessment opportunity  Standard UoL penalty applies  Assessment 1 There is no reassessment opportunity,  
Coursework  During practical ses  Semester 2  10  No reassessment opportunity  Standard UoL penalty applies  Assessment 2 There is no reassessment opportunity,  
Coursework  Out of class  Semester 2  10  Yes  Standard UoL penalty applies  Assessment 3 
Coursework  Out of class  Semester 2  40  Yes  Standard UoL penalty applies  Assessment 4 Notes (applying to all assessments) Assessment 226 will be a practical and data analysis exam Assessment 226.1 will be based on completing the coursework assignments within the laboratory class Assessment 226.2 will be based on completing pre-practical on-line questionnaires designed to guide student’s preparation for the next session and build on learning from the previous session. These will have a formative as well as summative role and be objective assessments (e.g. multiple choice and extended matching questions) Assessment 226.3 will be based on the generation of a group scientific report and poster and individual completion of problem solving exercises based on each session’s practical work (out of class) 

Aims

  • This module aims to:

     
    Provide students with a practical training that will help them to carry our projects in genetics;

  • Train students in the production and characterisation of specific deletion mutan ts, mutagen screening, cytogenetics and karyotype analysis, population studies, molecular analysis of genomes and bioinformatics;

  • Develop knowledge and understanding in genetics, and ability to apply, evaluate and interpret this knowledge to solve problems.

    		•

    Learning Outcomes

    On successful completion of this module students will be able to:

     
    Present, critically evaluate and interpret qualitative and quantitative data, and record procedures and protocols;

    Work individually and as part of a team , manage their time effectively and use laboratory equipment correctly and safely to generate data;

    Plan and execute a series of experiments to produce and characterise deletion mutants, screen mutagens, analyse karotypes, carry out population studies and molecular analysis of genomes and interogate bioinformatic databases ,

    Analyse data, interpret validity and apply statistical analyses.

    Teaching and Learning Strategies

    Lecture -

    This refers to timetabled lectures

    Laboratory Work -

    This refers to practical sessions in laboratories, including groupwork

    Workshop -

    This refers to a poster session held during session 6

    Assessment -

    This refers to scheduled time for in-course summative assessments

    Syllabus
    1 

    A series of practical exercises will be conducted, in which students will be set a series of problems that they have to address experimentally. Emphasis will be placed upon the design of experiments and the rational interpretation of experimental data obtained by the student. Where appropriate, students will work in teams to plan experiments/programmes of experiments, to carry out the experiments and to draw conclusions from pooled data. Experiments carried out are as follows. Note that most are carried out over several sessions

     
    Reverse genetics: Site-directed gene dis ruption in Aspergillus and characterisation of the resulting mutants.
     
    Bacterial Mutagenesis: Induction of mutations by UV light and chemical mutagens. The AMES assay.
     
    Genotyping and population genetic analysis: Genotyping the BIOL276 class population.
     
    Cytogenetics: Analysis of normal and abnormal chromosome spreads.
     
    Recombination and gene conversion in  Sordaria
     
    The module will culminate in a g roup poster presentation and an in-class final course assessment.

    Recommended Texts
    Reading lists are managed at readinglists.liverpool.ac.uk. Click here to access the reading lists for this module.
    Explanation of Reading List: