Module Specification |
| The information contained in this module specification was correct at the time of publication but may be subject to change, either during the session because of unforeseen circumstances, or following review of the module at the end of the session. Queries about the module should be directed to the member of staff with responsibility for the module. |
| Title | The Immune System in Health and Disease | ||
| Code | LIFE221 | ||
| Coordinator |
Dr LM McShane School of Life Sciences L.Mcshane@liverpool.ac.uk |
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| Year | CATS Level | Semester | CATS Value |
| Session 2016-17 | Level 5 FHEQ | First Semester | 15 |
Pre-requisites before taking this module (other modules and/or general educational/academic requirements): |
| None |
Modules for which this module is a pre-requisite: |
Co-requisite modules: |
Linked Modules: |
Teaching Schedule |
| Lectures | Seminars | Tutorials | Lab Practicals | Fieldwork Placement | Other | TOTAL | |
| Study Hours |
24 Formal lectures |
6 Structured case study problem solving workshops |
30 | ||||
| Timetable (if known) |
Lectures will be used to deliver the bulk of the syllabus
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Structured problem solving workshops based on clinical scenarios of immune system dysfunction
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| Private Study | 120 | ||||||
| TOTAL HOURS | 150 | ||||||
Assessment |
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| EXAM | Duration | Timing (Semester) |
% of final mark |
Resit/resubmission opportunity |
Penalty for late submission |
Notes |
| Unseen Written Exam | 120 | Semester 1 | 80 | Yes | Exam Notes (applying to all assessments) Assessment 1 consists of 4 online tests, spread throughout the semester. Assessment 2 will consist of an exam that includes MCQs and two sets of short, directed written pieces. The first set will be based on a clinical scenario that the students have seen in the problem solving workshops. The second set will be based on a clinical scenario that has not been covered in the workshops. | |
| CONTINUOUS | Duration | Timing (Semester) |
% of final mark |
Resit/resubmission opportunity |
Penalty for late submission |
Notes |
| Coursework | equivalent to approx | Semester 1 | 20 | Yes | Online test | |
Aims |
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This module aims to:
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Learning Outcomes |
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Identify the main components of the mammalian immune system |
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Assess the contribution of innate and adaptive immune mechanisms to host defences |
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Assess the mechanisms that permit recognition of an infinitely diverse microflora
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Discuss the impact of malfunction of immune processes on human health, and explain the bases of autoimmunity and allergy together with the mechanisms by which these can be minimised
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Discuss how dysfunction of immune system constituents can cause disease |
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Teaching and Learning Strategies |
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Lecture - Formal lectures Lectures will be used to deliver the bulk of the syllabus |
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Case Based Learning - Structured case study problem solving workshops Structured problem solving workshops based on clinical scenarios of immune system dysfunction |
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Syllabus |
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| 1 |
Innate vs Adaptive Immunity Cells and Organs of the Immune System Innate Immunity - Epithelial Surfaces and Complement - Cellular Response and Inflammation Adaptive Immunity - Lymphoid Development and Lympoid Tissue - Immunoglobulin Structure and Function- Generation of Antibody Divers ity - Humoral Immunity - T-cell Development and Selection, TH1, TH2, TH17 - T-cell Mediated Immunity - The Cellular Basis of Immunological Memory Immune Cell Signalling Cytokines MHC Structure and Diversity Antigen Presentation via the MHC I and II Pathways Mucosal Immunity Immunity to Bacteria and Bacterial Evasion Strategies Immunity to Viruses and Viral Evasion Strategies Immunity to Parasites and Parasite Evasion Strategies Failures of Host Defense Mechanisms - including clinical scenario case studies Allergy and Allergic Disease Autoimmunity and Transplantation Manipulating the Immune Response
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Recommended Texts |
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Reading lists are managed at readinglists.liverpool.ac.uk. Click here to access the reading lists for this module. Explanation of Reading List: |
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