Module Details |
The information contained in this module specification was correct at the time of publication but may be subject to change, either during the session because of unforeseen circumstances, or following review of the module at the end of the session. Queries about the module should be directed to the member of staff with responsibility for the module. |
Title | CATALYSIS | ||
Code | CHEM368 | ||
Coordinator |
Dr JA Iggo Chemistry J.A.Iggo@liverpool.ac.uk |
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Year | CATS Level | Semester | CATS Value |
Session 2016-17 | Level 6 FHEQ | Second Semester | 15 |
Pre-requisites before taking this module (or general academic requirements): |
Completion of years 1 and 2 of an MChem or BSc (Hons) Chemistry programme or, for PGT students, a BSc (Hons) Chemistry programme. |
Aims |
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The aim of this module is to give students a broad, interdisciplinary, background in catalysis across the traditional divides within chemistry. |
Learning Outcomes |
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By the end of the module, students should:
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Teaching and Learning Strategies |
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Lecture - |
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Tutorial - |
Syllabus |
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1 |
The module is divided into three components, as follows:
Inorganic Catalysis (Dr J A Iggo) The Inorganic Chemistry section of the module will introduce students to the application of organometallic complexes of transition metals in catalysis. Particular emphasis is placed on the mechanistic aspects of the subject. The approach is via worked examples chosen both for the commercial significance of the reaction and to illustrate how the catalytic mechanism can be studied. Organic and Bio-organic Catalysis (Dr R Bonar-Law) This section introduces the principles of chemical and biological catalysis: transition state and intermediate; the Hammond postulate, rate-determining step,simple kinetic analysis. Types of catalysis: General and specific acid/base catalysis, ele ctrophilic and nucleophilic catalysis, intra molecular catalysisand effective molarity. Isotope effects as a probe of mechanism. These principles will provide the basis and understanding for a discussion of important enzyme-catalysed reactions in a series of case studies. The role of specific active site amino-acids and co-factors in catalytic mechanisms will be stressed; detailed knowledge of protein structure will not be required. Enzyme kinetics (Michaelis-Menten); types of enzyme inhibition. Hydrolytic enzymes: catalytic mechanism of a -chymotrypsin-the prototype; synthetic applications of hydrolases. Catalysis by metal ions. Redox enzymes: dehydrogenases (NAD/NADH) and cytochromes. Carbon-carbon bond forming enzymes, especially Class I aldolases; thiamine pyrophosphate (TPP). Functional group-transforming enzymes: pyridoxalphosphate (PLP)-case study. This section of the module provides a link between "conventional" chemistry and th e chemistry of enzyme catalysis and shows students how the fundamental chemical mechanisms and principles are the same. A 50:50 split between chemical and biological catalysis will be aimed for. Heterogeneous Catalysis (Prof I Kozhevnikov) This set of lectures aims to give an integrated description of the basic principles of heterogeneous catalysis, including the role of active sites on the solid surface and importance of adsorption phenomena in the determination of reaction kinetics, and uses different classes of catalysts and well-known catalytic processes as examples to apply these notions. Also examined are the importance of transport limitations (heat and mass transfer) in porous solid catalysts and molecular shape selectivity in zeolite catalysts. A general view is thus provided of major factors which determine the behaviour of heterogeneous catalysts, and their importance is illustrated through the discussion of case examples selected from important catalytic applications. |
Recommended Texts |
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Reading lists are managed at readinglists.liverpool.ac.uk. Click here to access the reading lists for this module. Explanation of Reading List: |
Teaching Schedule |
Lectures | Seminars | Tutorials | Lab Practicals | Fieldwork Placement | Other | TOTAL | |
Study Hours |
30 |
6 |
36 | ||||
Timetable (if known) | |||||||
Private Study | 114 | ||||||
TOTAL HOURS | 150 |
Assessment |
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EXAM | Duration | Timing (Semester) |
% of final mark |
Resit/resubmission opportunity |
Penalty for late submission |
Notes |
Unseen Written Exam | 3 hr | Semester 2 | 80 | Yes | Standard UoL penalty applies | Assessment 2 Notes (applying to all assessments) 6 Problem Sets - work is not marked anonymously Written Examination Students to answer four questions from a choice of six. Questions will be a mix of "short answer" with some problem solving and essays. August resit for students if applicable. |
CONTINUOUS | Duration | Timing (Semester) |
% of final mark |
Resit/resubmission opportunity |
Penalty for late submission |
Notes |
Coursework | 6x8 hrs for 6 sets o | 2nd Semester | 20 | Yes | Standard UoL penalty applies | Assessment 1 |