Module Details |
The information contained in this module specification was correct at the time of publication but may be subject to change, either during the session because of unforeseen circumstances, or following review of the module at the end of the session. Queries about the module should be directed to the member of staff with responsibility for the module. |
Title | Heterocyclic Chemistry and Drug Synthesis | ||
Code | CHEM338 | ||
Coordinator |
Dr IA O'Neil Chemistry Ion@liverpool.ac.uk |
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Year | CATS Level | Semester | CATS Value |
Session 2024-25 | Level 6 FHEQ | Second Semester | 7.5 |
Pre-requisites before taking this module (or general academic requirements): |
Aims |
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The aim of the module is to present the synthesis and reactivity of the most important classes of heterocyclic compounds and to present case studies drawn from major drug classes. |
Learning Outcomes |
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(LO1) Students will be able to solve problems involving the structural features and reactivity of heterocyclic compounds, including stereochemistry. |
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(LO2) Students will be able to solve problems involving some of the major synthetic pathways in heterocyclic chemistry, including carbon-carbon and carbon-heteroatom bond formation, functional group interconversions and ring substitution. |
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(LO3) Students will be aware of the importance of heterocycles as key components in major drug classes and combinatorial libraries. |
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(LO4) Students will be able to solve problems involving the use of heterocycles in modern synthetic methodology. |
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(LO5) Students will be able to solve problems about three-dimensional structure in organic chemistry. |
Teaching and Learning Strategies |
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Lectures: 16 x 1 hr in person lectures. Recorded lectures are also available. Coursework: Two sets of assessment problems related to material presented in the lectures and similar in format to the exam paper. The problems are usually slightly more demanding than the exam questions and they may require students to carry out some independent research and use material covered in other core organic modules (basic carbonyl chemistry for example). Tutorials. 1 x 1 hr in-person tutorial (formative) at the end of the course. *Lectures: 16 |
Syllabus |
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* Introduction to heterocycles. Stereoelectronics of ring closing reactions. Baldwin's rules. The concept of "Chemical Space". |
Recommended Texts |
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Reading lists are managed at readinglists.liverpool.ac.uk. Click here to access the reading lists for this module. |
Teaching Schedule |
Lectures | Seminars | Tutorials | Lab Practicals | Fieldwork Placement | Other | TOTAL | |
Study Hours |
16 |
1 |
17 | ||||
Timetable (if known) | |||||||
Private Study | 58 | ||||||
TOTAL HOURS | 75 |
Assessment |
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EXAM | Duration | Timing (Semester) |
% of final mark |
Resit/resubmission opportunity |
Penalty for late submission |
Notes |
written exam Resit: A single resit including reassessment of the coursework. | 90 | 80 | ||||
CONTINUOUS | Duration | Timing (Semester) |
% of final mark |
Resit/resubmission opportunity |
Penalty for late submission |
Notes |
2 Assignments Exemptions: e-submission 3.2b Resit: No separate resit, reassessment is included in exam resit | 0 | 20 |