Module Details |
The information contained in this module specification was correct at the time of publication but may be subject to change, either during the session because of unforeseen circumstances, or following review of the module at the end of the session. Queries about the module should be directed to the member of staff with responsibility for the module. |
Title | Medicinal Chemistry of Anti-Infectives | ||
Code | CHEM335 | ||
Coordinator |
Prof PM O'Neill Chemistry P.M.Oneill01@liverpool.ac.uk |
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Year | CATS Level | Semester | CATS Value |
Session 2020-21 | Level 6 FHEQ | First Semester | 7.5 |
Pre-requisites before taking this module (or general academic requirements): |
CHEM231 ORGANIC CHEMISTRY II; CHEM248 AN INTRODUCTION TO MEDICINAL CHEMISTRY |
Aims |
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The aim of this module is to introduce students to the fundamental principles that underpin modern medicinal chemistry of anti-infective drugs; these will include qualitative and advanced quantitative SAR techniques, computer aided molecular design, further techniques in solid phase chemistry / combinatorial chemistry. The course will build on the principles taught in the introductory medicinal chemistry module CHEM248. |
Learning Outcomes |
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(LO1) By the end of the module students will have achieved a solid understanding of modern approaches to anti-infective drug design. In particular they should be able to show a clear understanding of: |
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(S1) Students will develop their chemistry-related cognitive abilities and skills i.e. abilities and skills relating to intellectual tasks, including problem solving as required by the Chemistry subject benchmark statement. In particular they will gain the ability to adapt and apply methodology to the solution of unfamiliar problems |
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(S2) Communication skills through online team meetings |
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(S3) Organisational skills |
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(S4) IT skills through computational workshops and online exercises |
Teaching and Learning Strategies |
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Lectures will be taught asynchronously via virtual learning environment (13 x 1h lectures with each lecture split into two halves), workshops (equivalent to 2x 2h) and associated assignments. Molecular modelling assignments will be supported virtually (e.g. via MS Teams and email). Each lecture will have discussion points and questions which will be covered in sequential lectures. In summary: |
Syllabus |
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Lecture 1 - Introduction; Recap of the process of drug discovery including revision of QSAR, combinatorial chemistry and HTS. Major therapeutic areas targeted in module will be discussed. |
Recommended Texts |
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Reading lists are managed at readinglists.liverpool.ac.uk. Click here to access the reading lists for this module. |
Teaching Schedule |
Lectures | Seminars | Tutorials | Lab Practicals | Fieldwork Placement | Other | TOTAL | |
Study Hours |
13 |
6 |
19 | ||||
Timetable (if known) | |||||||
Private Study | 56 | ||||||
TOTAL HOURS | 75 |
Assessment |
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EXAM | Duration | Timing (Semester) |
% of final mark |
Resit/resubmission opportunity |
Penalty for late submission |
Notes |
remote examination. 2 hours on task | 2 hours | 60 | ||||
CONTINUOUS | Duration | Timing (Semester) |
% of final mark |
Resit/resubmission opportunity |
Penalty for late submission |
Notes |
two problem based tutorials, one MCQ, and one tutorial/computer modelling exercise Standard UoL penalties apply for late submission. There is no re-submission opportunity. These assignments are not | 2 problem/computer m | 40 |