Photo of Dr Lakis Liloglou

Dr Lakis Liloglou B.Sc.(hons), Ph.D.

Senior Lecturer in molecular oncology Molecular and Clinical Cancer Medicine

    Research

    Research Interest 1

    Molecular biology of respirstory tract cancers. Epigenetic analysis and Biomarker development for early detection, patient statification and therapeutic monitoring.
    Genomic Instability and transposable elements.

    Research Group Membership

    Research Grants

    Bench fee support to student Ahmed al Khafaji

    REPUBLIC OF IRAQ MINISTRY OF EDUCATION

    September 2012 - August 2014

    Novel epigenetic biomarkers in the diagnosis of minimal residual disease in head and neck cancer.

    CANCER RESEARCH UK (CRUK) (UK)

    September 2007 - April 2009

    Validation of a DNA methylation signature in plasma as an early lung cancer diagnostic tool

    ROY CASTLE LUNG CANCER FOUNDATION (UK)

    September 2013 - August 2016

    Liverpool Lung Project - Genetic Instability.

    ROY CASTLE LUNG CANCER FOUNDATION (UK)

    January 2004 - December 2004

    Methylation - an early lung cancer diagnostic.

    ROY CASTLE LUNG CANCER FOUNDATION (UK)

    October 2002 - September 2005

    Validation of DNA methylation biomarkers for early lung cancer diagnosis in case-control populations and in a primary care high risk cohort population

    CANCER RESEARCH UK (CRUK) (UK)

    October 2010 - September 2012

    miRNA deregulation in respiratory cancers

    ROYAL SOCIETY (CHARITABLE)

    June 2011 - May 2013

    Long non-coding RNA biomarkers for early detection of lung cancer

    ROY CASTLE LUNG CANCER FOUNDATION (UK)

    November 2014 - December 2015

    Roy Castle Lung Cancer Research Programme

    ROY CASTLE LUNG CANCER FOUNDATION (UK)

    January 2006 - March 2018

    MicroRNA biomarkers in surrogate airway tissues for early lung cancer detection

    ROY CASTLE LUNG CANCER FOUNDATION (UK)

    July 2012 - February 2013

    Detection of oral squamous cell carcinoma using epigenetic markers in saliva-derived DNA

    BRITISH ASSOCIATION OF ORAL MAXILLOFACIAL SURGEONS (UK)

    April 2010 - March 2012

    The Liverpool Lung Project - Research Fellowship

    ROY CASTLE LUNG CANCER FOUNDATION (UK)

    January 2008 - December 2010

    Identification of early lung cancer genes using an in vitro carcinogenesis model in organotypic bronchial epithelial cell culture system.

    DEPARTMENT OF TRADE AND INDUSTRY (UK)

    May 2004 - November 2005

    Bench fee support for PhD student

    NIGER DELTA DEVELOPMENT COMMISSION (NDDC)(NIGERIA)

    October 2013 - September 2017

    Bench fees to support PhD student

    REPUBLIC OF IRAQ MINISTRY OF EDUCATION

    December 2013 - November 2016

    Research Collaborations

    Dr Janet Risk

    Internal

    Head and neck cancer

    Dr Aristides Eliopoulos

    External: University of Crete

    Investigation of the TPL-2 kinase status in lung cancer and contribution to inflammation - realted carcinogenesis.

    Dr Alex Santori

    External: Applied Biosystems

    Development of new quantitative method for DNA methylation detection

    Andreas Weinhäusel

    External: Austrian Research Centers GmbH - ARC

    DNA methylation targets for lung cancer diagnosis

    Volker Liebenberg

    External: Epigenomics, AG

    Epigenetic biomarkers for lung cancer detection

    Dr Mark Boyd

    Internal

    MDM2 impact on genome methylation maintenance

    Dr Neil Gibson

    External: AstraZeneca Pharmceuticals

    DNA methylation analysis for therapeutic stratification (information can not disclosed publically)

    Dr Richard Shaw

    Internal

    DNA methylation markers for the diagnosis/prognosis of head and neck tumours

    Dr Vassilis Gorgoulis

    External: University of Athens

    There is an on-going collaboration between the two labs for many years on genomic instability, DNA damage and lung cancer development