Dr Steven Lane PhD, MSc, BSc

Lecturer in Medical Statistics Biostatistics

    Research

    Research Interest 1

    Pharmacokinetics and Pharmacodynamics:
    Personalised Dosing Algorithms:
    Pharmacokinetics is the study of what the body does to a drug and Pharmacodynamics is the study of what a drug does to the body. As well as identifying the variables that contribute to inter-patient variability in the response to specific drugs (e.g. Warfarin), the aim is then to combine this information into personalised dosing algorithms to improve both the efficacy and safety of prescribed doses.

    Research Group Membership

    • Medical Statistics

    Research Grants

    The Impact of continuous haemofiltration with high volume fluid exchange during cardiopulmonary bypass surgery on the recovery of patients with impaired renal function- A pilot study

    DEPARTMENT OF HEALTH (UK) (NIHR)

    July 2010 - March 2012

    A pilot randomised control trial, in intensive care patients, comparing seven days versus two days treatment with empirical antibiotics to treat hospital acquired infection of unknown origins

    DEPARTMENT OF HEALTH (UK) (NIHR)

    January 2010 - March 2012

    A pilot study to assess whethr humidified oxygen is more effective than standard oxygen therapy in treating children with acute severe asthma

    DEPARTMENT OF HEALTH (UK) (NIHR)

    November 2013 - October 2016

    Research Collaborations

    Dr B. Matata

    External: Royal Liverpool and Broadgreen University Hospital NHS Trust

    I have collaborated on two successful HTA programme awards with Dr Matata and collegues

    A pilot randomised control trial comparing seven days verses two days of empirical antibiotics to treat hospital acquired infections of unknown origin in intensive care patients, NIHR Health Technology Assessment Programme, £170,000, Matata B, Toh C-H, Ruben M, Haycock A, Stables R., Scawn N. and Lane S.
    The impact of continuous haemofiltration with high volume fluid exchange during cardiopulmonary bypass surgery on the recovery of patients with impaired renal function- a pilot study, NIHR Health Technology Assessment Programme, Matata B, Toh C-H, Ruben M, Haycock A, Mediratta N., Jackson M., Sharma A., Stables R., Scawn N., and Lane S.