Dr Reynaldo Martina

ZZ (DO NOT USE) was Biostatistics

  • +44 (0)151 794 9701

    Publications

    2019

    A combined proof of concept and dose finding study with multiple endpoints: A Bayesian adaptive design in chronic prostatitis/chronic pelvic pain syndrome (Journal article)

    Martina, R., Houbiers, J., Melis, J., & van Till, O. (2019). A combined proof of concept and dose finding study with multiple endpoints: A Bayesian adaptive design in chronic prostatitis/chronic pelvic pain syndrome. BIOMETRICAL JOURNAL, 61(03), 476-487. doi:10.1002/bimj.201700210

    DOI: 10.1002/bimj.201700210

    2018

    The inclusion of real world evidence in clinical development planning (Journal article)

    Martina, R., Jenkins, D., Bujkiewicz, S., Dequen, P., & Abrams, K. (2018). The inclusion of real world evidence in clinical development planning. Trials, 19. doi:10.1186/s13063-018-2769-2

    DOI: 10.1186/s13063-018-2769-2

    Comparative effectiveness from a single-arm trial and real-world data: alectinib versus ceritinib. (Journal article)

    Davies, J., Martinec, M., Delmar, P., Coudert, M., Bordogna, W., Golding, S., . . . Crane, G. (2018). Comparative effectiveness from a single-arm trial and real-world data: alectinib versus ceritinib.. Journal of Comparative Effectiveness Research, 7(9), 855-865. doi:10.2217/cer-2018-0032

    DOI: 10.2217/cer-2018-0032

    Methods for the inclusion of real world evidence in network meta-analysis (Journal article)

    Jenkins, D., bujkiewicz, S., Martina, R. V., Dequen, P., & Abrams, K. R. (n.d.). Methods for the inclusion of real world evidence in network meta-analysis. https://arxiv.org/abs/1805.06839.

    qSOFA, SIRS and NEWS for predicting inhospital mortality and ICU admission in emergency admissions treated as sepsi (Journal article)

    Goulden, R., Hoyle, M. -C., Monis, J., Railton, D., Riley, V., Martin, P., . . . Nsutebu, E. (2018). qSOFA, SIRS and NEWS for predicting inhospital mortality and ICU admission in emergency admissions treated as sepsi. EMERGENCY MEDICINE JOURNAL, 35(6), 345-349. doi:10.1136/emermed-2017-207120

    DOI: 10.1136/emermed-2017-207120

    2017

    Fatty Acid Amide Hydrolase Inhibitor Treatment in Men With Chronic Prostatitis/Chronic Pelvic Pain Syndrome: An Adaptive Double-blind, Randomized Controlled Trial (Journal article)

    Wagenlehner, F., van Till, J. W. O., Houbiers, J. G. A., Martina, R. V., Cerneus, D. P., Melis, J. H. J. M., . . . Nickel, J. C. (2017). Fatty Acid Amide Hydrolase Inhibitor Treatment in Men With Chronic Prostatitis/Chronic Pelvic Pain Syndrome: An Adaptive Double-blind, Randomized Controlled Trial. Urology, 103, 191-197. doi:10.1016/j.urology.2017.02.029

    DOI: 10.1016/j.urology.2017.02.029

    2016

    A clinical perspective on the analysis and presentation of the number of incontinence episodes following treatment for OAB (Journal article)

    Martina, R., Kay, R., Abrams, P., van Maanen, R., & Ridder, A. (2016). A clinical perspective on the analysis and presentation of the number of incontinence episodes following treatment for OAB. Neurourology and urodynamics, 35(6), 728-732. doi:10.1002/nau.22787

    DOI: 10.1002/nau.22787

    Electronic bladder diaries of differing duration versus a paper diary for data collection in overactive bladder (Journal article)

    Abrams, P., Paty, J., Martina, R., Newgreen, D. T., van Maanen, R., Paireddy, A., . . . Ridder, A. (2016). Electronic bladder diaries of differing duration versus a paper diary for data collection in overactive bladder. Neurourology and Urodynamics, 35(6), 743-749. doi:10.1002/nau.22800

    DOI: 10.1002/nau.22800

    A quantitative benefit-risk assessment approach to improve decision making in drug development: Application of a multicriteria decision analysis model in the development of combination therapy for overactive bladder. (Journal article)

    de Greef-van der Sandt, I., Newgreen, D., Schaddelee, M., Dorrepaal, C., Martina, R., Ridder, A., & van Maanen, R. (2016). A quantitative benefit-risk assessment approach to improve decision making in drug development: Application of a multicriteria decision analysis model in the development of combination therapy for overactive bladder.. Clinical pharmacology and therapeutics, 99(4), 442-451. doi:10.1002/cpt.271

    DOI: 10.1002/cpt.271

    The analysis of incontinence episodes and other count data in patients with overactive bladder by Poisson and negative binomial regression (Journal article)

    Martina, R., Kay, R., Maanen, R. V., & Ridder, A. (2016). The analysis of incontinence episodes and other count data in patients with overactive bladder by Poisson and negative binomial regression. Pharmaceutical Statistics, 15(4), 379. doi:10.1002/pst.1752

    DOI: 10.1002/pst.1752

    2015

    The analysis of incontinence episodes and other count data in patients with overactive bladder by Poisson and negative binomial regression (Journal article)

    Martina, R., Kay, R., van Maanen, R., & Ridder, A. (2015). The analysis of incontinence episodes and other count data in patients with overactive bladder by Poisson and negative binomial regression. Pharmaceutical statistics, 14(2), 151-160. doi:10.1002/pst.1664

    DOI: 10.1002/pst.1664

    Combination treatment with mirabegron and solifenacin in patients with overactive bladder: efficacy and safety results from a randomised, double-blind, dose-ranging, phase 2 study (Symphony). (Journal article)

    Abrams, P., Kelleher, C., Staskin, D., Rechberger, T., Kay, R., Martina, R., . . . Ridder, A. (2015). Combination treatment with mirabegron and solifenacin in patients with overactive bladder: efficacy and safety results from a randomised, double-blind, dose-ranging, phase 2 study (Symphony).. European urology, 67(3), 577-588. doi:10.1016/j.eururo.2014.02.012

    DOI: 10.1016/j.eururo.2014.02.012

    • +44 (0)151 794 9701