Prof Paula Williamson

Professor of Medical Statistics Biostatistics

    Research

    Research Group Membership
    Research Grants
    • Side Lying Upper airway Maintenance in Babies Requiring Surgery for cleft palate repair (SLUMBRS)
    • improving orAl health in Cleft lip and/Or palate: a health pRomotion iNtervention for children and parents (ACORN)
    • Wellcome VIP Award
    • A prospective study of the aPTT waveform and lipoprotein-complexed C reactive protein assays in the early diagnosis and prognosis of sepsis
    • Use of the electronic health record in the design and conduct of clinical trials
    • Variability in response to warfarin: a prospective analysis of pharmacogenetic and environmental factors.
    • Technology Assessment Reviews (TARS).
    • An RCT of longer-term clinical outcomes and cost effectiveness of standard and new antiepileptic drugs.
    • Medicines for Children (MCRN) Clinical Trials Unit.
    • Medicines for Children Research Network Clinical Trials Unit
    • A pragmatic randomised controlled trial comparing the effectiveness and cost effectiveness of levetiracetam and zonisamide versus standard treatments for epilepsy: a comparison of Standard And New Antiepileptic Drugs (SANAD-II)
    • Health R&D NoW.
    • Clinical trial monitoring: establishing best UK practice?
    • Co-ordinating Centre of the UK Medicines for Children Research Network (MCRN.
    • UK Lung Cancer Screening Trial (UKLS) - feasibility study and protocol development.
    • DESIRE
    • NIHR Medicines for Children Research Network
    • Service agreement for medical statistics.
    • Research assistant in medical statistics.
    • Driving up the quality and relevance of research-based knowledge: the COMET (Core Outcome Measures in Effectiveness Trials) Initiative
    • MYPAN: Open label randomised controlled trial of mycophenolate mofetil versus cyclphoshamide for the induction of remission of childhood polyarteritis nodosa
    • Duration of intravenous antibiotic therapy for children with acute osteomyelitis or septic arthritis: a feasibility study
    • NIHR Clinician Scientist Award: Prediction and prevention of adverse pregnancy outcomes in women with chronic vascular disease
    • GORMET
    • Defining patient preferences and priorities for treatment options and outcomes in epilepsy
    • North West Hub for Trial Methodology Research (NWHTMR)
    • Prevention of colonisation with Pseudomonas aeruginosa for cystic fibrosis patients.
    • Development of a central resource for research in recruitment in clinical trials
    • Development of a quality assessment tool for core outcome set development
    • Understanding the process and impact of within-study selective reporting bias.
    • DexEnceph: Dexamethasone in Herpes Simplex Virus Encephalitis Randomised Controlled Trial.
    • UK Lung Cancer Screening Trial (UKLS)
    • Multi-centre feasibility study on the efficacy of insulin-like growth factor-1 (IGF-1) and growth hormone (GH) in children with Crohn's disease-induced growth failure
    • Consolidating guidelines for the prevention, detection and appraisal of reporting biases in clinical trials
    • A pragmatic randomised controlled trial of intravenous levetiracetam versus intravenous phenytoin in terminating acute, prolonged tonic-clonic seizures including convulsive status epilepticus in children, the 'EcLIPSE' Study: Emergency treatment with Levetiracetam or Phenytoin in Status Epilepticus
    • NIHR Research Methods Fellowship
    • COMET Health outcomes research and measurement workshop and collaboration with kyoto university
    • Tissue sample collection from the ESPAC Adjuvant Trials in pancreatic cancer
    • Onabotulinium toxin-A versus extended release tolterodine in the management of idiopathic overactive bladder in children: A pilot randomised controlled trial OVERT
    • Neighbourhood and Dementia: a mixed methods study
    • COMET
    • MerseyBeat - Best Evidence, Application and Translation of research
    • DfID exact title to be defined
    • Adverse Drug Reactions in Children
    • A pharmacogenomic approach to coumarin anticoagulant therapy (PACT)
    • Process in recruitment to randomised controlled trials (RCTs) of medicines for children.
    • Healing Foundation Clinical Trials Unit
    • Refractory Juvenile Myoclonoc Epilepsy Cohort (ReJuMEC)
    • Department of Health Sponsored chair in pharmacogenetics.
    • Statistical methodology for longitudinal studies in clinical research.
    • Skin to skin.
    • North West Research Design Services (Phase 2).
    • Phase IIa, randomised, open label, controlled trial of rostuvastatin for the prevention of aminoglycoside-induced kidney toxicity in children with cystic fibrosis (PROteKT)
    • Metformin and genetic polymorphisms of organic cation transporters.
    • Multi-centre randomised control trial comparing the clinical and cost effectiveness of trans-foraminal epidural steroid injection to surgical microdiscectomy for the treatment of chronic radicular pain secondary to prolapsed intervertebral disc herniation. (NErve Rootblock VErsus Surgery; NERVES)
    • MRC North West Hub for Trials Methodology Research
    • Recruitment and retention in clinical trials: current knowledge and future directions for research, the recruitment and retention workshop
    • PACIFICO Phase III multicentre trial comparing two different Rituximab-Chemotherapy induction regimens for Follicular Lymphoma in Older patients (PACIFIC)
    • MASCOT
    • Research Associate in Medical Statistics.
    • ORBIT II: Outcome Reporting Bias In Trials
    • A randomised controlled trial of Amnioinfusion versus conservative management In very early preterm premature rupture of membranes AMIPROM
    • Adverse Drug Reactions in Children.
    • Research Fellow in Medical Statistics
    • MAGnesium Nebuliser Trial (MAGNET) a randomised, placebo controlled study of nebulised magnesium in acute severe asthma in children.
    • Agreeing current good practice for clinical trial data sharing
    • Introducing personalised risk based intervals in screening for diabetic retinopathy: development, implementation and assessment of safety, cost-effectiveness and patient experience (ISDR study)
    • Pharmacogenetics of GABAergic mechanisms of benefit and harm in epilepsy.
    • Further understanding of medical conditions that can impact on child health in general and child dental health in particular.
    • North West Research Design Services
    • TAILoR (TelmisArtan and InsuLin Resistance in HIV): A dose-ranging Phase II randomised open trial of telmistartan as a strategy for the reduction of insulin resistance in HIV-positive individuals on Combination Antiretroviral Therapy (CART)
    • MOMENT The management of otitis media with effusion (OME) in children with cleft palate
    • NIHR Senior Investigator Award- Funding allocation to Alder Hey and Paula Williamson
    • Workshop on the design and analysis of clinical trials in Head and Neck Cancer