Photo of Prof Paul McNamara

Prof Paul McNamara MBBS MRCPCH PhD

Professor in Child Health, Honorary Consultant in Paediatric Respiratory Medicine Women's and Children's Health

Publications

Selected Publications

  1. Interleukin 9 production in the lungs of infants with severe respiratory syncytial virus bronchlolitis (Journal article - 2004)

2019

MVA-NP+M1 vaccine activates mucosal M1-specific T cell immunity and tissue-resident memory T cells in human nasopharynx-associated lymphoid tissue. (Journal article)

Puksuriwong, S., Ahmed, M. S., Sharma, R., Krishnan, M., Leong, S., Lambe, T., . . . Zhang, Q. (2019). MVA-NP+M1 vaccine activates mucosal M1-specific T cell immunity and tissue-resident memory T cells in human nasopharynx-associated lymphoid tissue.. The Journal of infectious diseases. doi:10.1093/infdis/jiz593

DOI: 10.1093/infdis/jiz593

Minimally Invasive Nasal Sampling in Children Offers Accurate Pneumococcal Colonization Detection (Journal article)

Nikolaou, E., Blizard, A., Pojar, S., Mitsi, E., German, E. L., Reine, J., . . . Jochems, S. P. (2019). Minimally Invasive Nasal Sampling in Children Offers Accurate Pneumococcal Colonization Detection. PEDIATRIC INFECTIOUS DISEASE JOURNAL, 38(11), 1147-1149. doi:10.1097/INF.0000000000002454

DOI: 10.1097/INF.0000000000002454

Epidemiology of Nontuberculous Mycobacteria Infection in Children and Young People With Cystic Fibrosis: Analysis of UK Cystic Fibrosis Registry (Journal article)

Gardner, A. I., McClenaghan, E., Saint, G., McNamara, P. S., Brodlie, M., & Thomas, M. F. (2019). Epidemiology of Nontuberculous Mycobacteria Infection in Children and Young People With Cystic Fibrosis: Analysis of UK Cystic Fibrosis Registry. CLINICAL INFECTIOUS DISEASES, 68(5), 731-737. doi:10.1093/cid/ciy531

DOI: 10.1093/cid/ciy531

Progression of whole-blood transcriptional signatures from interferon-induced to neutrophil-associated patterns in severe influenza (vol 19, pg 625, 2018) (Journal article)

Dunning, J., Blankley, S., Hoang, L. T., Cox, M., Graham, C. M., James, P. L., . . . Investigators, M. O. S. A. I. C. (2019). Progression of whole-blood transcriptional signatures from interferon-induced to neutrophil-associated patterns in severe influenza (vol 19, pg 625, 2018). NATURE IMMUNOLOGY, 20(3), 373. doi:10.1038/s41590-019-0328-y

DOI: 10.1038/s41590-019-0328-y

Contribution of respiratory viruses and bacteria to community-acquired pneumonia in highly vaccinated children: a case-control study. (Journal article)

Saint, G. L., Hawcutt, D. B., & McNamara, P. S. (2019). Contribution of respiratory viruses and bacteria to community-acquired pneumonia in highly vaccinated children: a case-control study.. Thorax. doi:10.1136/thoraxjnl-2018-212625

DOI: 10.1136/thoraxjnl-2018-212625

2018

Non-invasive ventilation for the management of children with bronchiolitis (NOVEMBR): a feasibility study and core outcome set development protocol (Journal article)

van Miert, C., Fernandes, R. M., Eccleson, H., Bedson, E., Lane, S., Peak, M., . . . McNamara, P. S. (2018). Non-invasive ventilation for the management of children with bronchiolitis (NOVEMBR): a feasibility study and core outcome set development protocol. TRIALS, 19. doi:10.1186/s13063-018-2969-9

DOI: 10.1186/s13063-018-2969-9

Adherence to Aerosol Therapy in Young People With Cystic Fibrosis: Patient and Parent Perspectives Following Electronic Data Capture. (Journal article)

O'Toole, D. P. H., Latchford, G. J., Duff, A. J. A., Ball, R., McCormack, P., McNamara, P. S., . . . Southern, K. W. (2019). Adherence to Aerosol Therapy in Young People With Cystic Fibrosis: Patient and Parent Perspectives Following Electronic Data Capture. QUALITATIVE HEALTH RESEARCH, 29(6), 846-856. doi:10.1177/1049732318805754

DOI: 10.1177/1049732318805754

Expression of the B cell differentiation factor BAFF and chemokine CXCL13 in a murine model of Respiratory Syncytial Virus infection (Journal article)

Alturaiki, W., McFarlane, A. J., Rose, K., Corkhill, R., McNamara, P. S., Schwarze, J., & Flanagan, B. F. (2018). Expression of the B cell differentiation factor BAFF and chemokine CXCL13 in a murine model of Respiratory Syncytial Virus infection. CYTOKINE, 110, 267-271. doi:10.1016/j.cyto.2018.01.014

DOI: 10.1016/j.cyto.2018.01.014

Respiratory readmission rates differ in the year following hospitalisation with RSV and non-RSV bronchiolitis (Conference Paper)

Saint, G., Flanagan, B., & Mcnamara, P. (2018). Respiratory readmission rates differ in the year following hospitalisation with RSV and non-RSV bronchiolitis. In EUROPEAN RESPIRATORY JOURNAL Vol. 52. doi:10.1183/13993003.congress-2018.PA4644

DOI: 10.1183/13993003.congress-2018.PA4644

Children's views on research without prior consent in emergency situations: a UK qualitative study (Journal article)

Roper, L., Sherratt, F. C., Young, B., McNamara, P., Dawson, A., Appleton, R., . . . Woolfall, K. (2018). Children's views on research without prior consent in emergency situations: a UK qualitative study. BMJ OPEN, 8(6). doi:10.1136/bmjopen-2018-022894

DOI: 10.1136/bmjopen-2018-022894

Progression of whole-blood transcriptional signatures from interferon-induced to neutrophil-associated patterns in severe influenza (Journal article)

Dunning, J., Blankley, S., Hoang, L. T., Cox, M., Graham, C. M., James, P. L., . . . Investigators, M. O. S. A. I. C. (2018). Progression of whole-blood transcriptional signatures from interferon-induced to neutrophil-associated patterns in severe influenza. NATURE IMMUNOLOGY, 19(6), 625-+. doi:10.1038/s41590-018-0111-5

DOI: 10.1038/s41590-018-0111-5

Activation and Induction of Antigen-Specific T Follicular Helper Cells Play a Critical Role in Live-Attenuated Influenza Vaccine-Induced Human Mucosal Anti-influenza Antibody Response (Journal article)

Aljurayyan, A., Puksuriwong, S., Ahmed, M., Sharma, R., Krishnan, M., Sood, S., . . . Zhang, Q. (2018). Activation and Induction of Antigen-Specific T Follicular Helper Cells Play a Critical Role in Live-Attenuated Influenza Vaccine-Induced Human Mucosal Anti-influenza Antibody Response. JOURNAL OF VIROLOGY, 92(11). doi:10.1128/JVI.00114-18

DOI: 10.1128/JVI.00114-18

Transaminase levels reflect disease severity in children ventilated for respiratory syncytial virus (RSV) bronchiolitis (Journal article)

Thorburn, K., Fulton, C., King, C., Ramaneswaran, D., Alammar, A., & McNamara, P. S. (2018). Transaminase levels reflect disease severity in children ventilated for respiratory syncytial virus (RSV) bronchiolitis. SCIENTIFIC REPORTS, 8. doi:10.1038/s41598-018-20292-6

DOI: 10.1038/s41598-018-20292-6

Accumulation mode particles and LPS exposure induce TLR-4 dependent and independent inflammatory responses in the lung (Journal article)

Fonceca, A. M., Zosky, G. R., Bozanich, E. M., Sutanto, E. N., Kicic, A., McNamara, P. S., . . . Stick, S. M. (2018). Accumulation mode particles and LPS exposure induce TLR-4 dependent and independent inflammatory responses in the lung. RESPIRATORY RESEARCH, 19. doi:10.1186/s12931-017-0701-z

DOI: 10.1186/s12931-017-0701-z

2017

Recovery of hypothalamo-pituitary-adrenal axis suppression during treatment with inhaled corticosteroids for childhood asthma (Journal article)

Gangadharan, A., McCoy, P., Phyo, A., McGuigan, M. P., Dharmaraj, P., Ramakrishnan, R., . . . Blair, J. (2017). Recovery of hypothalamo-pituitary-adrenal axis suppression during treatment with inhaled corticosteroids for childhood asthma. JOURNAL OF ASTHMA AND ALLERGY, 10, 317-326. doi:10.2147/JAA.S142874

DOI: 10.2147/JAA.S142874

Novel FOXA2 mutation causes Hyperinsulinism, Hypopituitarism with Craniofacial and Endoderm-derived organ abnormalities (Journal article)

Giri, D., Vignola, M. L., Gualtieri, A., Scagliotti, V., McNamara, P., Peak, M., . . . Senniappan, S. (2017). Novel FOXA2 mutation causes Hyperinsulinism, Hypopituitarism with Craniofacial and Endoderm-derived organ abnormalities. HUMAN MOLECULAR GENETICS, 26(22), 4315-4326. doi:10.1093/hmg/ddx318

DOI: 10.1093/hmg/ddx318

Novel compound heterozygous ASXL3 mutation causing Bainbridge-ropers like syndrome and primary IGF1 deficiency. (Journal article)

Giri, D., Rigden, D., Didi, M., Peak, M., McNamara, P., & Senniappan, S. (2017). Novel compound heterozygous ASXL3 mutation causing Bainbridge-ropers like syndrome and primary IGF1 deficiency.. International journal of pediatric endocrinology, 2017, 8. doi:10.1186/s13633-017-0047-9

DOI: 10.1186/s13633-017-0047-9

Predicting Risk of Serious Bacterial Infections in Febrile Children in the Emergency Department (Journal article)

Irwin, A. D., Grant, A., Williams, R., Kolamunnage-Dona, R., Drew, R. J., Paulus, S., . . . Carrol, E. D. (2017). Predicting Risk of Serious Bacterial Infections in Febrile Children in the Emergency Department. PEDIATRICS, 140(2). doi:10.1542/peds.2016-2853

DOI: 10.1542/peds.2016-2853

M1-like monocytes are a major immunological determinant of severity in previously healthy adults with life-threatening influenza (Journal article)

Cole, S. L., Dunning, J., Kok, W. L., Benam, K. H., Benlahrech, A., Repapi, E., . . . Investigators, M. O. S. A. I. C. (2017). M1-like monocytes are a major immunological determinant of severity in previously healthy adults with life-threatening influenza. JCI INSIGHT, 2(7). doi:10.1172/jci.insight.91868

DOI: 10.1172/jci.insight.91868

2016

A critical role of T follicular helper cells in human mucosal anti-influenza response that can be enhanced by immunological adjuvant CpG-DNA (Journal article)

Aljurayyan, A. N., Sharma, R., Upile, N., Beer, H., Vaughan, C., Xie, C., . . . Zhang, Q. (2016). A critical role of T follicular helper cells in human mucosal anti-influenza response that can be enhanced by immunological adjuvant CpG-DNA. ANTIVIRAL RESEARCH, 132, 122-130. doi:10.1016/j.antiviral.2016.05.021

DOI: 10.1016/j.antiviral.2016.05.021

Weakly acidic pH reduces inflammatory cytokine expression in airway epithelial cells (Journal article)

Hackett, A. P., Trinick, R. E., Rose, K., Flanagan, B. F., & McNamara, P. S. (2016). Weakly acidic pH reduces inflammatory cytokine expression in airway epithelial cells. RESPIRATORY RESEARCH, 17. doi:10.1186/s12931-016-0399-3

DOI: 10.1186/s12931-016-0399-3

Activation of cross-reactive mucosal T and B cell responses in human nasopharynx-associated lymphoid tissue in vitro by Modified Vaccinia Ankara-vectored influenza vaccines (Journal article)

Mullin, J., Ahmed, M. S., Sharma, R., Upile, N., Beer, H., Achar, P., . . . Zhang, Q. (2016). Activation of cross-reactive mucosal T and B cell responses in human nasopharynx-associated lymphoid tissue in vitro by Modified Vaccinia Ankara-vectored influenza vaccines. VACCINE, 34(14), 1688-1695. doi:10.1016/j.vaccine.2016.02.028

DOI: 10.1016/j.vaccine.2016.02.028

Characterisation Of The Neutrophil In Respiratory Syncytial Virus Bronchiolitis (Conference Paper)

Saint, G. L., Smyth, R., Flanagan, B. F., & McNamara, P. S. (2016). Characterisation Of The Neutrophil In Respiratory Syncytial Virus Bronchiolitis. In AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Vol. 193. Retrieved from http://gateway.webofknowledge.com/

Rhinovirus-C detection in children presenting with acute respiratory infection to hospital in Brazil (Journal article)

Fawkner-Corbett, D. W., Khoo, S. K., Duarte, C. M., Bezerra, P. G. M., Bochkov, Y. A., Gern, J. E., . . . McNamara, P. S. (2016). Rhinovirus-C detection in children presenting with acute respiratory infection to hospital in Brazil. JOURNAL OF MEDICAL VIROLOGY, 88(1), 58-63. doi:10.1002/jmv.24300

DOI: 10.1002/jmv.24300

2015

Saline in Acute Bronchiolitis RCT and Economic evaluation: hypertonic saline in acute bronchiolitis - randomised controlled trial and systematic review (Journal article)

Everard, M. L., Hind, D., Ugonna, K., Freeman, J., Bradburn, M., Dixon, S., . . . Cross, E. (2015). Saline in Acute Bronchiolitis RCT and Economic evaluation: hypertonic saline in acute bronchiolitis - randomised controlled trial and systematic review. HEALTH TECHNOLOGY ASSESSMENT, 19(66), 1-+. doi:10.3310/hta19660

DOI: 10.3310/hta19660

Impaired Antibody-mediated Protection and Defective IgA B-Cell Memory in Experimental Infection of Adults with Respiratory Syncytial Virus (Journal article)

Habibi, M. S., Jozwik, A., Makris, S., Dunning, J., Paras, A., DeVincenzo, J. P., . . . Influenza, M. S. A. (2015). Impaired Antibody-mediated Protection and Defective IgA B-Cell Memory in Experimental Infection of Adults with Respiratory Syncytial Virus. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 191(9), 1040-1049. doi:10.1164/rccm.201412-2256OC

DOI: 10.1164/rccm.201412-2256OC

Cross-reactive immunity against influenza viruses in children and adults following 2009 pandemic H1N1 infection (Journal article)

Ahmed, M. S., Jacques, L. C., Mahallawi, W., Ferrara, F., Temperton, N., Upile, N., . . . Zhang, Q. (2015). Cross-reactive immunity against influenza viruses in children and adults following 2009 pandemic H1N1 infection. ANTIVIRAL RESEARCH, 114, 106-112. doi:10.1016/j.antiviral.2014.12.008

DOI: 10.1016/j.antiviral.2014.12.008

An Observational Study Examining the Relationship between Respiratory Symptoms, Airway Inflammation and Bacteriology in Children with Severe Neurodisability (Journal article)

Trinick, R. E., Bunni, L., Thorburn, K., Hackett, A. P., Dalzell, M., & McNamara, P. S. (2015). An Observational Study Examining the Relationship between Respiratory Symptoms, Airway Inflammation and Bacteriology in Children with Severe Neurodisability. PLOS ONE, 10(4). doi:10.1371/journal.pone.0124627

DOI: 10.1371/journal.pone.0124627

Blood eosinophils as a marker of likely corticosteroid response in children with preschool wheeze: time for an eosinophil guided clinical trial? (Journal article)

Gaillard, E. A., McNamara, P. S., Murray, C. S., Pavord, I. D., & Shields, M. D. (2015). Blood eosinophils as a marker of likely corticosteroid response in children with preschool wheeze: time for an eosinophil guided clinical trial?. CLINICAL AND EXPERIMENTAL ALLERGY, 45(9), 1384-1395. doi:10.1111/cea.12535

DOI: 10.1111/cea.12535

Etiology of Childhood Bacteremia and Timely Antibiotics Administration in the Emergency Department (Journal article)

Irwin, A. D., Drew, R. J., Marshall, P., Nguyen, K., Hoyle, E., Macfarlane, K. A., . . . Carrol, E. D. (2015). Etiology of Childhood Bacteremia and Timely Antibiotics Administration in the Emergency Department. PEDIATRICS, 135(4), 635-642. doi:10.1542/peds.2014-2061

DOI: 10.1542/peds.2014-2061

2014

SABRE: a multicentre randomised control trial of nebulised hypertonic saline in infants hospitalised with acute bronchiolitis (Journal article)

Everard, M. L., Hind, D., Ugonna, K., Freeman, J., Bradburn, M., Cooper, C. L., . . . Team, S. A. B. R. E. S. (2014). SABRE: a multicentre randomised control trial of nebulised hypertonic saline in infants hospitalised with acute bronchiolitis. THORAX, 69(12), 1105-1112. doi:10.1136/thoraxjnl-2014-205953

DOI: 10.1136/thoraxjnl-2014-205953

Turnover of strains and intraclonal variation amongst Pseudomonas aeruginosa isolates from paediatric CF patients (Journal article)

Hall, A. J., Fothergill, J. L., McNamara, P. S., Southern, K. W., & Winstanley, C. (2014). Turnover of strains and intraclonal variation amongst Pseudomonas aeruginosa isolates from paediatric CF patients. DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE, 80(4), 324-326. doi:10.1016/j.diagmicrobio.2014.09.007

DOI: 10.1016/j.diagmicrobio.2014.09.007

Accumulation of Human-Adapting Mutations during Circulation of A(H1N1)pdm09 Influenza Virus in Humans in the United Kingdom (Journal article)

Elderfield, R. A., Watson, S. J., Godlee, A., Adamson, W. E., Thompson, C. I., Dunning, J., . . . Investigators, M. O. S. A. I. C. (2014). Accumulation of Human-Adapting Mutations during Circulation of A(H1N1)pdm09 Influenza Virus in Humans in the United Kingdom. JOURNAL OF VIROLOGY, 88(22), 13269-13283. doi:10.1128/JVI.01636-14

DOI: 10.1128/JVI.01636-14

Activation of memory Th17 cells by domain 4 pneumolysin in human nasopharynx-associated lymphoid tissue and its association with pneumococcal carriage (Journal article)

Gray, C., Ahmed, M. S., Mubarak, A., Kasbekar, A. V., Derbyshire, S., McCormick, M. S., . . . Zhang, Q. (2014). Activation of memory Th17 cells by domain 4 pneumolysin in human nasopharynx-associated lymphoid tissue and its association with pneumococcal carriage. MUCOSAL IMMUNOLOGY, 7(3), 705-717. doi:10.1038/mi.2013.89

DOI: 10.1038/mi.2013.89

Airway Expression Of The B Cell Differentiation Factor Baff And Chemokine Cxcl13 In A Murine Model Of Human Respiratory Syncytial Virus Infection (Conference Paper)

Flanagan, B., McFarlane, A., Al-Turaiki, W., Fitch, P., Slupsky, J., McNamara, P. S., & Schwarze, J. (2014). Airway Expression Of The B Cell Differentiation Factor Baff And Chemokine Cxcl13 In A Murine Model Of Human Respiratory Syncytial Virus Infection. In AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Vol. 189. Retrieved from http://gateway.webofknowledge.com/

Characterisation of acute respiratory infections at a United Kingdom paediatric teaching hospital: observational study assessing the impact of influenza A (2009 pdmH1N1) on predominant viral pathogens (Journal article)

Lees, E. A., Carrol, E. D., Gerrard, C., Hardiman, F., Howel, G., Timmis, A., . . . McNamara, P. S. (2014). Characterisation of acute respiratory infections at a United Kingdom paediatric teaching hospital: observational study assessing the impact of influenza A (2009 pdmH1N1) on predominant viral pathogens. BMC INFECTIOUS DISEASES, 14. doi:10.1186/1471-2334-14-343

DOI: 10.1186/1471-2334-14-343

Cytokine Inflammatory Responses In Children With Acute Respiratory Infections By Different Viruses And Atypical Bacteria (Conference Paper)

Bezerra, P. G. D. M., Duarte, M. M. B., McNamara, P. S., Britto, M. A. D., Rose, K., Cuevas, L. E., . . . Correia, J. D. B. (2014). Cytokine Inflammatory Responses In Children With Acute Respiratory Infections By Different Viruses And Atypical Bacteria. In AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Vol. 189. Retrieved from http://gateway.webofknowledge.com/

Cytokines Do Not Predict Admission Patterns Or Need For Oxygen In Infants With Respiratory Syncytial Virus (Conference Paper)

Duarte, M. M. B., McNamara, P. S., Bezerra, P. G. D. M., Britto, M. A. D., Cuevas, L. E., Rose, K., . . . Correia, J. D. B. (2014). Cytokines Do Not Predict Admission Patterns Or Need For Oxygen In Infants With Respiratory Syncytial Virus. In AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Vol. 189. Retrieved from http://gateway.webofknowledge.com/

Development and validation of the Liverpool infant bronchiolitis severity score: a research protocol (Journal article)

van Miert, C., Abbott, J., Verheoff, F., Lane, S., Carter, B., & McNamara, P. (2014). Development and validation of the Liverpool infant bronchiolitis severity score: a research protocol. JOURNAL OF ADVANCED NURSING, 70(10), 2353-2362. doi:10.1111/jan.12387

DOI: 10.1111/jan.12387

Respiratory Symptoms Increase With Increasing Neurodisability (Conference Paper)

Bunni, L., Turner, L., Mohamed, S., & McNamara, P. S. (2014). Respiratory Symptoms Increase With Increasing Neurodisability. In AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Vol. 189. Retrieved from http://gateway.webofknowledge.com/

Respiratory Syncytial Virus Is Taken Up By Neutrophils And Can Be Visualised By Confocal Microscopy Throughout The Cytoplasm (Conference Paper)

Saint, G. L., Smyth, R. L., Flanagan, B. F., & McNamara, P. S. (2014). Respiratory Syncytial Virus Is Taken Up By Neutrophils And Can Be Visualised By Confocal Microscopy Throughout The Cytoplasm. In AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Vol. 189. Retrieved from http://gateway.webofknowledge.com/

The B Lymphocyte Differentiation Factor (BAFF) Is Expressed in the Airways of Children with CF and in Lungs of Mice Infected with Pseudomonas aeruginosa (Journal article)

Neill, D. R., Saint, G. L., Bricio-Moreno, L., Fothergill, J. L., Southern, K. W., Winstanley, C., . . . Flanagan, B. F. (2014). The B Lymphocyte Differentiation Factor (BAFF) Is Expressed in the Airways of Children with CF and in Lungs of Mice Infected with Pseudomonas aeruginosa. PLOS ONE, 9(5). doi:10.1371/journal.pone.0095892

DOI: 10.1371/journal.pone.0095892

2013

Respiratory Viruses and Atypical Bacteria (Chapter)

McNamara, P. S., & Van Doorn, H. R. (2014). Respiratory Viruses and Atypical Bacteria. In Manson's Tropical Infectious Diseases (pp. 215-224.e2). Elsevier. doi:10.1016/b978-0-7020-5101-2.00020-0

DOI: 10.1016/b978-0-7020-5101-2.00020-0

After a long wait, two arrive, one after the other! (Journal article)

Southern, K. W., McCormack, P., & McNamara, P. S. (2013). After a long wait, two arrive, one after the other!. THORAX, 68(4), 311-312. doi:10.1136/thoraxjnl-2012-202891

DOI: 10.1136/thoraxjnl-2012-202891

Adherence to nebulised therapies in adolescents with cystic fibrosis is best on week-days during school term-time (Journal article)

Ball, R., Southern, K. W., McCormack, P., Duff, A. J. A., Brownlee, K. G., & McNamara, P. S. (2013). Adherence to nebulised therapies in adolescents with cystic fibrosis is best on week-days during school term-time. JOURNAL OF CYSTIC FIBROSIS, 12(5), 440-444. doi:10.1016/j.jcf.2012.12.012

DOI: 10.1016/j.jcf.2012.12.012

Comparison of real time diagnostic chemistries to detect Pseudomonas aeruginosa in respiratory samples from cystic fibrosis patients (Journal article)

Fothergill, J. L., Ledson, M. J., Walshaw, M. J., McNamara, P. S., Southern, K. W., & Winstanley, C. (2013). Comparison of real time diagnostic chemistries to detect Pseudomonas aeruginosa in respiratory samples from cystic fibrosis patients. JOURNAL OF CYSTIC FIBROSIS, 12(6), 675-681. doi:10.1016/j.jcf.2013.04.007

DOI: 10.1016/j.jcf.2013.04.007

Infection with 2009 H1N1 Influenza Virus Primes for Immunological Memory in Human Nose-Associated Lymphoid Tissue, Offering Cross-Reactive Immunity to H1N1 and Avian H5N1 Viruses (Journal article)

Mahallawi, W. H., Kasbekar, A. V., McCormick, M. S., Hoschler, K., Temperton, N., Leong, S. C., . . . Zhang, Q. (2013). Infection with 2009 H1N1 Influenza Virus Primes for Immunological Memory in Human Nose-Associated Lymphoid Tissue, Offering Cross-Reactive Immunity to H1N1 and Avian H5N1 Viruses. JOURNAL OF VIROLOGY, 87(10), 5331-5339. doi:10.1128/JVI.03547-12

DOI: 10.1128/JVI.03547-12

Infection with 2009 H1N1 influenza virus primes for immunological memory in human nose-associated lymphoid tissue, offering cross-reactive immunity to H1N1 and avian H5N1 viruses. (Journal article)

Mahallawi, W. H., Kasbekar, A. V., McCormick, M. S., Hoschler, K., Temperton, N., Leong, S. C., . . . Zhang, Q. (2013). Infection with 2009 H1N1 influenza virus primes for immunological memory in human nose-associated lymphoid tissue, offering cross-reactive immunity to H1N1 and avian H5N1 viruses.. Journal of virology, 87(10), 5331-5339. doi:10.1128/JVI.03547-12

DOI: 10.1128/JVI.03547-12

Intraclonal genetic diversity amongst cystic fibrosis and keratitis isolates of Pseudomonas aeruginosa (Journal article)

Hall, A. J., Fothergill, J. L., Kaye, S. B., Neal, T. J., McNamara, P. S., Southern, K. W., & Winstanley, C. (2013). Intraclonal genetic diversity amongst cystic fibrosis and keratitis isolates of Pseudomonas aeruginosa. JOURNAL OF MEDICAL MICROBIOLOGY, 62, 208-216. doi:10.1099/jmm.0.048272-0

DOI: 10.1099/jmm.0.048272-0

Respiratory syncytial virus infection of airway epithelial cells, in vivo and in vitro, supports pulmonary antibody responses by inducing expression of the B cell differentiation factor BAFF (Journal article)

McNamara, P. S., Fonceca, A. M., Howarth, D., Correia, J. B., Slupsky, J. R., Trinick, R. E., . . . Flanagan, B. F. (2013). Respiratory syncytial virus infection of airway epithelial cells, in vivo and in vitro, supports pulmonary antibody responses by inducing expression of the B cell differentiation factor BAFF. THORAX, 68(1), 76-81. doi:10.1136/thoraxjnl-2012-202288

DOI: 10.1136/thoraxjnl-2012-202288

2012

THE IMPACT OF THE H1N1 INFLUENZA PANDEMIC ON CLINICAL PRESENTATIONS AND VIRAL EPIDEMIOLOGY OF ACUTE RESPIRATORY INFECTION IN PRESCHOOL CHILDREN IN BRAZIL (Journal article)

Fawkner-Corbett, D. W., Duarte, M. D. C. M. B., Rose, K., Fonceca, A., Bezerra, P., Hopkins, M., . . . McNamara, P. S. (2012). THE IMPACT OF THE H1N1 INFLUENZA PANDEMIC ON CLINICAL PRESENTATIONS AND VIRAL EPIDEMIOLOGY OF ACUTE RESPIRATORY INFECTION IN PRESCHOOL CHILDREN IN BRAZIL. PEDIATRIC INFECTIOUS DISEASE JOURNAL, 31(6), 653-655. doi:10.1097/INF.0b013e3182501ff4

DOI: 10.1097/INF.0b013e3182501ff4

Reply to Kahn (Journal article)

Halfhide, C. P., Flanagan, B. F., Brearey, S. P., Hunt, J. A., Fonceca, A. M., McNamara, P. S., . . . Smyth, R. L. (2012). Reply to Kahn. Journal of Infectious Diseases, 205(4), 693-694. doi:10.1093/infdis/jir823

DOI: 10.1093/infdis/jir823

Assessing the Liverpool Respiratory Symptom Questionnaire in children with cystic fibrosis (Journal article)

Trinick, R., Southern, K. W., & McNamara, P. S. (2012). Assessing the Liverpool Respiratory Symptom Questionnaire in children with cystic fibrosis. EUROPEAN RESPIRATORY JOURNAL, 39(4), 899-905. doi:10.1183/09031936.00070311

DOI: 10.1183/09031936.00070311

Bronchiolitis (Chapter)

Thorburn, K., & McNamara, P. S. (2014). Bronchiolitis. In Pediatric Critical Care Medicine (pp. 75-85). Springer London. doi:10.1007/978-1-4471-6356-5_5

DOI: 10.1007/978-1-4471-6356-5_5

IFITM3 restricts the morbidity and mortality associated with influenza (Journal article)

Everitt, A. R., Clare, S., Pertel, T., John, S. P., Wash, R. S., Smith, S. E., . . . Investigators, M. O. S. A. I. C. (2012). IFITM3 restricts the morbidity and mortality associated with influenza. NATURE, 484(7395), 519-U146. doi:10.1038/nature10921

DOI: 10.1038/nature10921

Intraclonal genetic diversity amongst cystic fibrosis and keratitis isolates of Pseudomonas aeruginosa. (Journal article)

Hall, A. J., Fothergill, J. L., Kaye, S. B., Neal, T. J., McNamara, P. S., Southern, K. W., & Winstanley, C. (2013). Intraclonal genetic diversity amongst cystic fibrosis and keratitis isolates of Pseudomonas aeruginosa.. Journal of medical microbiology, 62(Pt 2), 208-216. doi:10.1099/jmm.0.048272-0

DOI: 10.1099/jmm.0.048272-0

New Nebulizer Technology to Monitor Adherence and Nebulizer Performance in Cystic Fibrosis (Journal article)

McCormack, P., Southern, K. W., & McNamara, P. S. (2012). New Nebulizer Technology to Monitor Adherence and Nebulizer Performance in Cystic Fibrosis. JOURNAL OF AEROSOL MEDICINE AND PULMONARY DRUG DELIVERY, 25(6), 307-309. doi:10.1089/jamp.2011.0934

DOI: 10.1089/jamp.2011.0934

Reflux aspiration in children with neurodisability-a significant problem, but can we measure it? (Journal article)

Trinick, R., Johnston, N., Dalzell, A. M., & McNamara, P. S. (2012). Reflux aspiration in children with neurodisability-a significant problem, but can we measure it?. JOURNAL OF PEDIATRIC SURGERY, 47(2), 291-298. doi:10.1016/j.jpedsurg.2011.11.019

DOI: 10.1016/j.jpedsurg.2011.11.019

The impact of the H1N1 influenza pandemic on clinical presentations and viral epidemiology of acute respiratory infection in preschool children in Brazil. (Journal article)

Fawkner-Corbett, D. W., Duarte, M. C. M. B., Rose, K., Fonceca, A., Bezerra, P., Hopkins, M., . . . McNamara, P. S. (2012). The impact of the H1N1 influenza pandemic on clinical presentations and viral epidemiology of acute respiratory infection in preschool children in Brazil.. The Pediatric infectious disease journal, 31(6), 653-655. doi:10.1097/INF.0b013e3182501ff4

DOI: 10.1097/INF.0b013e3182501ff4

2011

A randomised controlled trial of breathing modes for adaptive aerosol delivery in children with cystic fibrosis (Journal article)

McCormack, P., McNamara, P. S., & Southern, K. W. (2011). A randomised controlled trial of breathing modes for adaptive aerosol delivery in children with cystic fibrosis. JOURNAL OF CYSTIC FIBROSIS, 10(5), 343-349. doi:10.1016/j.jcf.2011.04.006

DOI: 10.1016/j.jcf.2011.04.006

Array tube genotyping of Pseudomonas aeruginosa isolates as a strategy for identifying potential emerging transmissible strains. (Journal article)

Hall, A. J., Fothergill, J. L., Southern, K. W., McNamara, P. S., Ledson, M. J., Walshaw, M. J., & Winstanley, C. (2011). Array tube genotyping of Pseudomonas aeruginosa isolates as a strategy for identifying potential emerging transmissible strains.. Journal of Cystic Fibrosis, 10 (S1, S32.

Characterisation of Regulatory T Cells in Nasal Associated Lymphoid Tissue in Children: Relationships with Pneumococcal Colonization (Journal article)

Zhang, Q., Leong, S. C., McNamara, P. S., Mubarak, A., Malley, R., & Finn, A. (2011). Characterisation of Regulatory T Cells in Nasal Associated Lymphoid Tissue in Children: Relationships with Pneumococcal Colonization. PLOS PATHOGENS, 7(8). doi:10.1371/journal.ppat.1002175

DOI: 10.1371/journal.ppat.1002175

Primary airway epithelial cultures from children are highly permissive to respiratory syncytial virus infection (Journal article)

Fonceca, A. M., Flanagan, B. F., Trinick, R., Smyth, R. L., & McNamara, P. S. (2012). Primary airway epithelial cultures from children are highly permissive to respiratory syncytial virus infection. THORAX, 67(1), 42-48. doi:10.1136/thoraxjnl-2011-200131

DOI: 10.1136/thoraxjnl-2011-200131

Viral and Atypical Bacterial Detection in Acute Respiratory Infection in Children Under Five Years (Journal article)

Bezerra, P. G. M., Britto, M. C. A., Correia, J. B., Duarte, M. D. C. M. B., Fonceca, A. M., Rose, K., . . . McNamara, P. S. (2011). Viral and Atypical Bacterial Detection in Acute Respiratory Infection in Children Under Five Years. PLOS ONE, 6(4). doi:10.1371/journal.pone.0018928

DOI: 10.1371/journal.pone.0018928

2010

Microarray genotyping of Pseudomonas aeruginosa isolates from CF units. (Journal article)

Hall, A. J., Fothergill, J. L., Southern, K. W., McNamara, P. S., Ledson, M. J., Walshaw, M. J., & Winstanley, C. (2010). Microarray genotyping of Pseudomonas aeruginosa isolates from CF units.. Journal of Cystic Fibrosis, 9(S1), S30.

2009

Open adherence monitoring using routine data download from an adaptive aerosol delivery nebuliser in children with cystic fibrosis (Journal article)

McNamara, P. S., McCormack, P., McDonald, A. J., Heaf, L., & Southern, K. W. (2009). Open adherence monitoring using routine data download from an adaptive aerosol delivery nebuliser in children with cystic fibrosis. JOURNAL OF CYSTIC FIBROSIS, 8(4), 258-263. doi:10.1016/j.jcf.2009.04.006

DOI: 10.1016/j.jcf.2009.04.006

A reducing prevalence of the Liverpool Epidemic Strain of Pseudomonas aeruginosa in children attending the index paediatric clinic. (Journal article)

Morris, D., Fallon, L., Heaf, L., Burrows, E. F., Wallace, H., McNamara, P. S., . . . Southern, K. W. (2009). A reducing prevalence of the Liverpool Epidemic Strain of Pseudomonas aeruginosa in children attending the index paediatric clinic.. Ped Pulmonol, 32, 325.

2007

Impact of human Metapneumovirus and Respiratory Syncytial Virus co-infection in severe bronchiolitis (Journal article)

McNamara, P. S., Flanagan, B. F., Smyth, R. L., & Hart, C. A. (2007). Impact of human Metapneumovirus and Respiratory Syncytial Virus co-infection in severe bronchiolitis. PEDIATRIC PULMONOLOGY, 42(8), 740-743. doi:10.1002/ppul.20649

DOI: 10.1002/ppul.20649

2005

Dual infection of infants by human metapneumovirus and human respiratory syncytial virus is strongly associated with severe bronchiolitis (Journal article)

Semple, M. G., Cowell, A., Dove, W., Greensill, J., McNamara, P. S., Halfhide, C., . . . Hart, C. A. (2005). Dual infection of infants by human metapneumovirus and human respiratory syncytial virus is strongly associated with severe bronchiolitis. JOURNAL OF INFECTIOUS DISEASES, 191(3), 382-386. doi:10.1086/426457

DOI: 10.1086/426457

Interleukin-9 as a possible therapeutic target in both asthma and chronic obstructive airways disease (Journal article)

McNamara, P. S., & Smyth, R. L. (2005). Interleukin-9 as a possible therapeutic target in both asthma and chronic obstructive airways disease. DRUG NEWS & PERSPECTIVES, 18(10), 615-621. doi:10.1358/dnp.2005.18.10.959575

DOI: 10.1358/dnp.2005.18.10.959575

Production of chemokines in the lungs of infants with severe respiratory syncytial virus bronchiolitis (Journal article)

McNamara, P. S., Flanagan, B. F., Hart, C. A., & Smyth, R. L. (2005). Production of chemokines in the lungs of infants with severe respiratory syncytial virus bronchiolitis. JOURNAL OF INFECTIOUS DISEASES, 191(8), 1225-1232. doi:10.1086/428855

DOI: 10.1086/428855

2004

Cytokines in severe Respiratory Syncytial Virus bronchiolitis (Thesis / Dissertation)

McNamara, P. S. (2004). Cytokines in severe Respiratory Syncytial Virus bronchiolitis. (PhD Thesis, The University of Liverpool).

Interleukin 9 production in the lungs of infants with severe respiratory syncytial virus bronchlolitis (Journal article)

McNamara, P. S., Flanagan, B. F., Baldwin, L. M., Newland, P., Hart, C. A., & Smyth, R. L. (2004). Interleukin 9 production in the lungs of infants with severe respiratory syncytial virus bronchlolitis. LANCET, 363(9414), 1031-1037. doi:10.1016/S0140-6736(04)15838-8

DOI: 10.1016/S0140-6736(04)15838-8

Pro- and anti-inflammatory responses in respiratory syncytial virus bronchiolitis (Journal article)

McNamara, P. S., Flanagan, B. F., Selby, A. M., Hart, C. A., & Smyth, R. L. (2004). Pro- and anti-inflammatory responses in respiratory syncytial virus bronchiolitis. EUROPEAN RESPIRATORY JOURNAL, 23(1), 106-112. doi:10.1183/09031936.03.00048103

DOI: 10.1183/09031936.03.00048103

2003

Bronchoalveolar lavage cellularity in infants with severe respiratory syncytial virus bronchiolitis (Journal article)

McNamara, P. S., Ritson, P., Selby, A., Hart, C. A., & Smyth, R. L. (2003). Bronchoalveolar lavage cellularity in infants with severe respiratory syncytial virus bronchiolitis. ARCHIVES OF DISEASE IN CHILDHOOD, 88(10), 922-926. doi:10.1136/adc.88.10.922

DOI: 10.1136/adc.88.10.922

Human metapneumovirus in severe respiratory syncytial virus bronchiolitis (Journal article)

Greensill, J., McNamara, P. S., Dove, W., Flanagan, B., Smyth, R. L., & Hart, C. A. (2003). Human metapneumovirus in severe respiratory syncytial virus bronchiolitis. EMERGING INFECTIOUS DISEASES, 9(3), 372-375. doi:10.3201/eid0903.020289

DOI: 10.3201/eid0903.020289

2002

A parent completed questionnaire to describe the patterns of wheezing and other respiratory symptoms in infants and preschool children (Journal article)

Powell, C. V. E., McNamara, P., Solis, A., & Shaw, N. J. (2002). A parent completed questionnaire to describe the patterns of wheezing and other respiratory symptoms in infants and preschool children. ARCHIVES OF DISEASE IN CHILDHOOD, 87(5), 376-379. doi:10.1136/adc.87.5.376

DOI: 10.1136/adc.87.5.376

The pathogenesis of respiratory syncytial virus disease in childhood (Journal article)

McNamara, P. S., & Smyth, R. L. (2002). The pathogenesis of respiratory syncytial virus disease in childhood. BRITISH MEDICAL BULLETIN, 61, 13-28. doi:10.1093/bmb/61.1.13

DOI: 10.1093/bmb/61.1.13

2001

Headache and abdominal pain (Journal article)

McNamara, P. S., Mallucci, C. L., & Appleton, R. T. (2001). Headache and abdominal pain. LANCET, 357(9260), 930. doi:10.1016/S0140-6736(00)04215-X

DOI: 10.1016/S0140-6736(00)04215-X