Photo of Dr Laura Bonnett

Dr Laura Bonnett PhD CStat FHEA

Tenure Track Fellow Biostatistics

Publications

Selected Publications

  1. External Validation of a Prognostic Model for Seizure Recurrence Following a First Unprovoked Seizure and Implications for Driving (Journal article - 2014)
  2. Prognostic factors for time to treatment failure and time to 12 months of remission for patients with focal epilepsy: post-hoc, subgroup analyses of data from the SANAD trial (Journal article - 2012)
  3. Prognostic factors for time to treatment failure and time to 12 month remission for patients with generalised epilepsy: post-hoc and subgroup analyses of SANAD (Conference Paper - 2012)
  4. Seizure recurrence after antiepileptic drug withdrawal and the implications for driving: further results from the MRC Antiepileptic Drug Withdrawal Study and a systematic review (Journal article - 2011)
  5. Risk of recurrence after a first seizure and implications for driving: further analysis of the Multicentre study of early Epilepsy and Single Seizures (Journal article - 2010)

2019

General health complaints and sleep associated with new injury within an endurance sporting population: A prospective study (Journal article)

Johnston, R., Cahalan, R., Bonnett, L., Maguire, M., Glasgow, P., Madigan, S., . . . Comyns, T. (2019). General health complaints and sleep associated with new injury within an endurance sporting population: A prospective study. Journal of Science and Medicine in Sport. doi:10.1016/j.jsams.2019.10.013

DOI: 10.1016/j.jsams.2019.10.013

IMPROVED SURVIVAL PREDICTION AND COMPARISON OF PROGNOSTIC MODELS FOR PATIENTS WITH HEPATOCELLULAR CARCINOMA TREATED WITH SORAFENIB (Journal article)

Labeur, T., Berhane, S., Edeline, J., Blanc, J. -F., Bettinger, D., Meyer, T., . . . Johnson, P. (2019). IMPROVED SURVIVAL PREDICTION AND COMPARISON OF PROGNOSTIC MODELS FOR PATIENTS WITH HEPATOCELLULAR CARCINOMA TREATED WITH SORAFENIB. HEPATOLOGY, 70, 525A-526A. Retrieved from http://gateway.webofknowledge.com/

Antibiotics for COPD exacerbations: does drug or duration matter? A primary care database analysis. (Journal article)

Stolbrink, M., Bonnett, L. J., & Blakey, J. D. (2019). Antibiotics for COPD exacerbations: does drug or duration matter? A primary care database analysis.. BMJ open respiratory research, 6(1), e000458. doi:10.1136/bmjresp-2019-000458

DOI: 10.1136/bmjresp-2019-000458

Predictors of severe asthma attack re-attendance in Ecuadorian children: a cohort study. (Journal article)

Ardura-Garcia, C., Arias, E., Hurtado, P., Bonnett, L. J., Sandoval, C., Maldonado, A., . . . Blakey, J. D. (2019). Predictors of severe asthma attack re-attendance in Ecuadorian children: a cohort study.. The European respiratory journal. doi:10.1183/13993003.02419-2018

DOI: 10.1183/13993003.02419-2018

An apparent paradox: resistance mutations in HIV-1 DNA predict improved virological responses to antiretroviral therapy (Journal article)

Geretti, A. M., Abdullahi, A., Fopoussi, O. M., Bonnett, L., Defo, V. F., Moudourou, S., . . . Torimiro, J. (2019). An apparent paradox: resistance mutations in HIV-1 DNA predict improved virological responses to antiretroviral therapy. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 74(10), 3011-3015. doi:10.1093/jac/dkz264

DOI: 10.1093/jac/dkz264

What is the correlation between patient-reported outcome measure (PROM) scores and patient satisfaction following elective reverse total shoulder replacement? (Journal article)

Daw, R. L. C., Gibson, J., Prescot, D., Bonnett, L., & Smith, M. (2019). What is the correlation between patient-reported outcome measure (PROM) scores and patient satisfaction following elective reverse total shoulder replacement?. Shoulder & elbow, 11(2 Suppl), 42-47. doi:10.1177/1758573217744178

DOI: 10.1177/1758573217744178

Non-blanchable erythema for predicting pressure ulcer development: a systematic review with an individual participant data meta-analysis. (Journal article)

Shi, C., Bonnett, L. J., Dumville, J. C., & Cullum, N. (2019). Nonblanchable erythema for predicting pressure ulcer development: a systematic review with an individual participant data meta-analysis. BRITISH JOURNAL OF DERMATOLOGY. doi:10.1111/bjd.18154

DOI: 10.1111/bjd.18154

Training Load and Baseline Characteristics Associated With New Injury/Pain Within an Endurance Sporting Population: A Prospective Study (Journal article)

Johnston, R., Cahalan, R., Bonnett, L., Maguire, M., Nevill, A., Glasgow, P., . . . Comyns, T. (2019). Training Load and Baseline Characteristics Associated With New Injury/Pain Within an Endurance Sporting Population: A Prospective Study. INTERNATIONAL JOURNAL OF SPORTS PHYSIOLOGY AND PERFORMANCE, 14(5), 590-597. doi:10.1123/ijspp.2018-0644

DOI: 10.1123/ijspp.2018-0644

Guide to presenting clinical prediction models for use in clinical settings (Journal article)

Bonnett, L. J., Snell, K. I. E., Collins, G. S., & Riley, R. D. (2019). Guide to presenting clinical prediction models for use in clinical settings. BMJ-BRITISH MEDICAL JOURNAL, 365. doi:10.1136/bmj.l737

DOI: 10.1136/bmj.l737

Identifying patients who will not reachieve remission after breakthrough seizures (Journal article)

Hughes, D. M., Bonnett, L. J., Marson, A. G., & Garcia-Finana, M. (2019). Identifying patients who will not reachieve remission after breakthrough seizures. EPILEPSIA, 60(4), 774-782. doi:10.1111/epi.14697

DOI: 10.1111/epi.14697

Investigating populations via penguins and their poo! (Journal article)

Bonnett, L. J., & White, S. (2019). Investigating populations via penguins and their poo!. Teaching Statistics: an international journal for teachers.

A Systematic Review of Methodology Used in the Development of Prediction Models for Future Asthma Attack (Conference Paper)

Bonnett, L., Bridge, J., & Blakey, J. D. (2019). A Systematic Review of Methodology Used in the Development of Prediction Models for Future Asthma Attack. In AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Vol. 199. Retrieved from http://gateway.webofknowledge.com/

2018

Modelling Seizures in Epilepsy - An Alternative to the Cox Model (Conference Paper)

Bonnett, L., Hutton, J., Smith, C. T., & Marson, A. (2018). Modelling Seizures in Epilepsy - An Alternative to the Cox Model. In EPILEPSIA Vol. 59 (pp. S343). Retrieved from http://gateway.webofknowledge.com/

Can acoustic radiation force imaging of the liver and spleen predict the presence of gastroesophageal varices? (Journal article)

Wiles, R., Patanwala, I., Hankinson, B., Healey, P., Farrell, C., Griffin, C., . . . Richardson, P. (2018). Can acoustic radiation force imaging of the liver and spleen predict the presence of gastroesophageal varices?. CLINICAL RADIOLOGY, 73(12), 1046-1051. doi:10.1016/j.crad.2018.07.199

DOI: 10.1016/j.crad.2018.07.199

Mitigating bias in observational vaccine effectiveness studies using simulated comparator populations: Application to rotavirus vaccination in the UK (Journal article)

Hungerford, D., Vivancos, R., Read, J. M., Bonnett, L. J., Bar-Zeev, N., Iturriza-Gomara, M., . . . French, N. (2018). Mitigating bias in observational vaccine effectiveness studies using simulated comparator populations: Application to rotavirus vaccination in the UK. VACCINE, 36(45), 6674-6682. doi:10.1016/j.vaccine.2018.09.051

DOI: 10.1016/j.vaccine.2018.09.051

Amoxicillin is associated with a lower risk of further antibiotic prescriptions for lower respiratory tract infections in primary care - A database analysis spanning over 30 years. (Journal article)

Stolbrink, M., Bonnett, L. J., & Blakey, J. D. (2018). Amoxicillin is associated with a lower risk of further antibiotic prescriptions for lower respiratory tract infections in primary care - A database analysis spanning over 30 years.. European clinical respiratory journal, 5(1), 1529535. doi:10.1080/20018525.2018.1529535

DOI: 10.1080/20018525.2018.1529535

Antibiotic Choice and Duration Associate with Repeat Prescriptions in Infective Asthma Exacerbations (Journal article)

Stolbrink, M., Bonnett, L. J., & Blakey, J. D. (2019). Antibiotic Choice and Duration Associate with Repeat Prescriptions in Infective Asthma Exacerbations. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE, 7(2), 548-+. doi:10.1016/j.jaip.2018.07.049

DOI: 10.1016/j.jaip.2018.07.049

Identification of patients who will not achieve seizure remission within 5 years on AEDs (Journal article)

Hughes, D. M., Bonnett, L. J., Czanner, G., Komarek, A., Marson, A. G., & Garcia-Finana, M. (2018). Identification of patients who will not achieve seizure remission within 5 years on AEDs. NEUROLOGY, 91(22), E2035-E2044. doi:10.1212/WNL.0000000000006564

DOI: 10.1212/WNL.0000000000006564

Variation in the length and structure of reports written by reporting radiographers: A retrospective study (Journal article)

Manning-Stanley, A. S., Bonnett, L., Mellett, T., Herreran, J. R., & Anforth, R. (2018). Variation in the length and structure of reports written by reporting radiographers: A retrospective study.. Radiography (London, England : 1995), 24(4), 383-391. doi:10.1016/j.radi.2018.06.005

DOI: 10.1016/j.radi.2018.06.005

What Factors Affect Treatment Failure When Antibiotics Are Given for Asthma Exacerbations? A Database Analysis (Conference Paper)

Stolbrink, M., Bonnett, L. J., & Blakey, J. D. (2018). What Factors Affect Treatment Failure When Antibiotics Are Given for Asthma Exacerbations? A Database Analysis. In AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Vol. 197. Retrieved from http://gateway.webofknowledge.com/

Incidence, aetiology, and sequelae of viral meningitis in UK adults: a multicentre prospective observational cohort study (Journal article)

McGill, F., Griffiths, M. J., Bonnett, L. J., Geretti, A. M., Michael, B. D., Beeching, N. J., . . . Investigators, U. K. M. S. (2018). Incidence, aetiology, and sequelae of viral meningitis in UK adults: a multicentre prospective observational cohort study. LANCET INFECTIOUS DISEASES, 18(9), 992-1003. doi:10.1016/S1473-3099(18)30245-7

DOI: 10.1016/S1473-3099(18)30245-7

Biased sampling: an investigation to promote discussion (Journal article)

White, S., & Bonnett, L. J. (2018). Biased sampling: an investigation to promote discussion. Teaching Statistics: an international journal for teachers.

Linezolid pharmacokinetics in MDR-TB: a systematic review, meta-analysis and Monte Carlo simulation (Journal article)

Millard, J., Pertinez, H., Bonnett, L., Hodel, E. M., Dartois, V., Johnson, J. L., . . . Sloan, D. J. (2018). Linezolid pharmacokinetics in MDR-TB: a systematic review, meta-analysis and Monte Carlo simulation. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 73(7), 1755-1762. doi:10.1093/jac/dky096

DOI: 10.1093/jac/dky096

Linezolid pharmacokinetics in multidrug resistant tuberculosis (MDR TB): a systematic review, meta-analysis and Monte Carlo simulation (Journal article)

Millard, J., Pertinez, H., Bonnett, L. J., Hodel, E., Dartois, V., Johnson, J. L., . . . Sloan, D. (2018). Linezolid pharmacokinetics in multidrug resistant tuberculosis (MDR TB): a systematic review, meta-analysis and Monte Carlo simulation. Journal of Antimicrobial Chemotherapy.

Quality of reporting of outcomes in phase III studies of pulmonary tuberculosis: a systematic review (Journal article)

Bonnett, L. J., Ken-Dror, G., & Davies, G. R. (2018). Quality of reporting of outcomes in phase III studies of pulmonary tuberculosis: a systematic review. TRIALS, 19. doi:10.1186/s13063-018-2522-x

DOI: 10.1186/s13063-018-2522-x

May the odds be ever in your favour. (Journal article)

Bonnett, L. J., & White, S. R. (2018). May the odds be ever in your favour.. Teaching statistics, 40(3), 94-97. doi:10.1111/test.12162

DOI: 10.1111/test.12162

The inter-rater reliability and prognostic value of coma scales in Nepali children with acute encephalitis syndrome (Journal article)

Ray, S., Rayamajhi, A., Bonnett, L. J., Solomon, T., Kneen, R., & Griffiths, M. J. (2018). The inter-rater reliability and prognostic value of coma scales in Nepali children with acute encephalitis syndrome. PAEDIATRICS AND INTERNATIONAL CHILD HEALTH, 38(1), 60-65. doi:10.1080/20469047.2017.1398503

DOI: 10.1080/20469047.2017.1398503

2017

Effectiveness of protease inhibitor/nucleos(t)ide reverse transcriptase inhibitor-based second-line antiretroviral therapy for the treatment of HIV-1 infection in sub-Saharan Africa: systematic review and meta-analysis. (Journal article)

Stockdale, A. J., Saunders, M. J., Boyd, M. A., Bonnett, L. J., Johnston, V., Wandeler, G., . . . Geretti, A. M. (2018). Effectiveness of Protease Inhibitor/Nucleos(t)ide Reverse Transcriptase Inhibitor-Based Second-line Antiretroviral Therapy for the Treatment of Human Immunodeficiency Virus Type 1 Infection in Sub-Saharan Africa: A Systematic Review and Meta-analysis. CLINICAL INFECTIOUS DISEASES, 66(12), 1846-1857. doi:10.1093/cid/cix1108

DOI: 10.1093/cid/cix1108

BREAKTHROUGH SEIZURES - FURTHER ANALYSIS OF THE STANDARD VS. NEW ANTIEPILEPTIC DRUGS (SANAD) STUDY (Conference Paper)

Bonnett, L., Powell, G., Smith, C. T., & Marson, A. (2017). BREAKTHROUGH SEIZURES - FURTHER ANALYSIS OF THE STANDARD VS. NEW ANTIEPILEPTIC DRUGS (SANAD) STUDY. In EPILEPSIA Vol. 58 (pp. S57). Retrieved from http://gateway.webofknowledge.com/

Breakthrough seizures-Further analysis of the Standard versus New Antiepileptic Drugs (SANAD) study (Journal article)

Bonnett, L. J., Powell, G. A., Smith, C. T., & Marson, A. G. (2017). Breakthrough seizures-Further analysis of the Standard versus New Antiepileptic Drugs (SANAD) study. PLOS ONE, 12(12). doi:10.1371/journal.pone.0190035

DOI: 10.1371/journal.pone.0190035

BREAKTHROUGH SEIZURES - FURTHER ANALYSIS OF THE SANAD STUDY (Conference Paper)

Bonnett, L., Powell, G., Smith, C. T., & Marson, A. (2017). BREAKTHROUGH SEIZURES - FURTHER ANALYSIS OF THE SANAD STUDY. In JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY Vol. 88 (pp. A22). doi:10.1136/jnnp-2017-ABN.74

DOI: 10.1136/jnnp-2017-ABN.74

INCIDENCE AND HEALTHCARE COSTS OF VIRAL MENINGITIS IN ADULTS - A MULTICENTRE PROSPECTIVE OBSERVATIONAL STUDY IN ENGLAND (Conference Paper)

McGill, F., Griffiths, M. J., Bonnett, L., Martin, A., Geretti, A. M., Michael, B. D., . . . Investigators, U. K. M. S. (2017). INCIDENCE AND HEALTHCARE COSTS OF VIRAL MENINGITIS IN ADULTS - A MULTICENTRE PROSPECTIVE OBSERVATIONAL STUDY IN ENGLAND. In JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY Vol. 88 (pp. A73). doi:10.1136/jnnp-2017-ABN.253

DOI: 10.1136/jnnp-2017-ABN.253

Minimally Invasive Epicardial Surgical Ablation Alone Versus Hybrid Ablation for Atrial Fibrillation: A Systematic Review and Meta-Analysis. (Journal article)

Pearman, C. M., Poon, S. S., Bonnett, L. J., Haldar, S., Wong, T., Mediratta, N., & Gupta, D. (2017). Minimally Invasive Epicardial Surgical Ablation Alone Versus Hybrid Ablation for Atrial Fibrillation: A Systematic Review and Meta-Analysis.. Arrhythmia & electrophysiology review, 6(4), 202-209. doi:10.15420/aer/2017.29.2

DOI: 10.15420/aer/2017.29.2

NEUROPSYCHOLOGICAL SEQUELAE OF VIRAL MENINGITIS (Conference Paper)

Adan, G., Griffiths, M., Bonnett, L., Miller, A., Geretti, A. M., Michael, B., . . . Solomon, T. (2017). NEUROPSYCHOLOGICAL SEQUELAE OF VIRAL MENINGITIS. In JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY Vol. 88 (pp. A68). doi:10.1136/jnnp-2017-ABN.235

DOI: 10.1136/jnnp-2017-ABN.235

USING ROUTINELY RECORDED DATA IN A CLINICAL TRIAL (Conference Paper)

Powell, G., Bonnett, L., Tudur-Smith, C., Hughes, D., Williamson, P., & Marson, T. (2017). USING ROUTINELY RECORDED DATA IN A CLINICAL TRIAL. In JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY Vol. 88 (pp. A75). doi:10.1136/jnnp-2017-ABN.261

DOI: 10.1136/jnnp-2017-ABN.261

The Influence of Cytomegalovirus on Expression of HLA-G and its Ligand KIR2DL4 by Human Peripheral Blood Leucocyte Subsets (Journal article)

Albayati, Z., Alyami, A., Alomar, S., Middleton, D., Bonnett, L., Aleem, S., . . . Christmas, S. E. (2017). The Influence of Cytomegalovirus on Expression of HLA-G and its Ligand KIR2DL4 by Human Peripheral Blood Leucocyte Subsets. SCANDINAVIAN JOURNAL OF IMMUNOLOGY, 86(5), 396-407. doi:10.1111/sji.12594

DOI: 10.1111/sji.12594

Prevalence of hepatitis D virus infection in sub-Saharan Africa: a systematic review and meta-analysis (vol 5, pg e992, 2016) (Journal article)

Stockdale, A. J., Chaponda, M., & Beloukas, A. (2017). Prevalence of hepatitis D virus infection in sub-Saharan Africa: a systematic review and meta-analysis (vol 5, pg e992, 2016). LANCET GLOBAL HEALTH, 5(11), E1079. Retrieved from http://gateway.webofknowledge.com/

EARLY IDENTIFICATION OF PATIENTS WITH DRUG-RESISTANT EPILEPSY (Poster)

Hughes, D. M., Bonnett, L. J., Czanner, G., Komarek, A., Marson, A., & Garcia-Finana, M. (2017). EARLY IDENTIFICATION OF PATIENTS WITH DRUG-RESISTANT EPILEPSY. Poster session presented at the meeting of Unknown Conference. Retrieved from http://gateway.webofknowledge.com/

Using routinely recorded data in the UK to assess outcomes in a randomised controlled trial: The Trials of Access (Journal article)

Powell, G., Bonnett, L., Tudur-Smith, C., Hughes, D., Marson, A., & Williamson, P. (2017). Using routinely recorded data in the UK to assess outcomes in a randomised controlled trial: The Trials of Access. TRIALS, 18. Retrieved from http://gateway.webofknowledge.com/

Dynamic Longitudinal Discriminant Analysis: Statistical and clinical findings from The DiALog project (Presentation material)

Hughes., Komarek, A., Bonnett, L. J., Czanner, G., Marson, A., & Garcia-Finana, M. (2017). Dynamic Longitudinal Discriminant Analysis: Statistical and clinical findings from The DiALog project. Statistical Analysis of Multi-Outcome Data (SAM) 2017.

Risk of a seizure recurrence after a breakthrough seizure and the implications for driving: further analysis of the standard versus new antiepileptic drugs (SANAD) randomised controlled trial (Journal article)

Bonnett, L. J., Powell, G. A., Smith, C. T., & Marson, A. G. (2017). Risk of a seizure recurrence after a breakthrough seizure and the implications for driving: further analysis of the standard versus new antiepileptic drugs (SANAD) randomised controlled trial. BMJ OPEN, 7(7). doi:10.1136/bmjopen-2017-015868

DOI: 10.1136/bmjopen-2017-015868

Pulmonary Vein Re-Isolation as a Routine Strategy Regardless of Symptoms: The PRESSURE Randomized Controlled Trial. (Journal article)

Das, M., Wynn, G. J., Saeed, Y., Gomes, S., Morgan, M., Ronayne, C., . . . Gupta, D. (2017). Pulmonary Vein Re-Isolation as a Routine Strategy Regardless of Symptoms: The PRESSURE Randomized Controlled Trial.. JACC. Clinical electrophysiology, 3(6), 602-611. doi:10.1016/j.jacep.2017.01.016

DOI: 10.1016/j.jacep.2017.01.016

Dynamic classification using credible intervals in longitudinal discriminant analysis (Journal article)

Hughes, D. M., Komarek, A., Bonnett, L. J., Czanner, G., & Garcia-Finana, M. (2017). Dynamic classification using credible intervals in longitudinal discriminant analysis. STATISTICS IN MEDICINE, 36(24), 3858-3874. doi:10.1002/sim.7397

DOI: 10.1002/sim.7397

Comparing the Efficacy of Drug Regimens for Pulmonary Tuberculosis: Meta-analysis of Endpoints in Early-Phase Clinical Trials (Journal article)

Bonnett, L. J., Ken-Dror, G., Koh, G. C. K. W., & Davies, G. R. (2017). Comparing the Efficacy of Drug Regimens for Pulmonary Tuberculosis: Meta-analysis of Endpoints in Early-Phase Clinical Trials. CLINICAL INFECTIOUS DISEASES, 65(1), 46-54. doi:10.1093/cid/cix247

DOI: 10.1093/cid/cix247

2016

Liver stiffness and virologic outcomes after introducing tenofovir as part of antiretroviral therapy in lamivudine-experienced adults with HIV and hepatitis B virus (HBV) co-infection in Ghana: four-year follow up of the prospective HEPIK cohort (Conference Paper)

Stockdale, A., Phillips, R. O., Sarfo, F. S., Appiah, L. T., Bonnett, L. J., Chadwicks, D., . . . Geretti, A. M. (2016). Liver stiffness and virologic outcomes after introducing tenofovir as part of antiretroviral therapy in lamivudine-experienced adults with HIV and hepatitis B virus (HBV) co-infection in Ghana: four-year follow up of the prospective HEPIK cohort. In HEPATOLOGY Vol. 64 (pp. 942A). Retrieved from http://gateway.webofknowledge.com/

Discriminant Function Analysis for Longitudinal Data (DiALog): Applications in Medical Research (Poster)

Hughes., Czanner, G., Cox, T., Bonnett, L., Harding, S., Marson, A., . . . Van der Hoek, M. (2016). Discriminant Function Analysis for Longitudinal Data (DiALog): Applications in Medical Research. Poster session presented at the meeting of 2016 MRC Festival of Medical Science. Liverpool.

Non-tumour Bone Marrow Lymphocytes Correlate with Improved Overall Survival in Childhood Acute Lymphoblastic Leukaemia (Journal article)

Edwin, C., Dean, J., Bonnett, L. J., Phillips, K., & Keenan, R. (n.d.). Non-tumour Bone Marrow Lymphocytes Correlate with Improved Overall Survival in Childhood Acute Lymphoblastic Leukaemia. Pediatric Blood and Cancer.

Ablation index, a novel marker of ablation lesion quality: prediction of pulmonary vein reconnection at repeat electrophysiology study and regional differences in target values (Journal article)

Das, M., Loveday, J. J., Wynn, G. J., Gomes, S., Saeed, Y., Bonnett, L. J., . . . Gupta, D. (2017). Ablation index, a novel marker of ablation lesion quality: prediction of pulmonary vein reconnection at repeat electrophysiology study and regional differences in target values. EUROPACE, 19(5), 775-783. doi:10.1093/europace/euw105

DOI: 10.1093/europace/euw105

The gamma-glutamyl transpeptidase to platelet ratio (GPR) shows poor correlation with transient elastography measurements of liver fibrosis in HIV-positive patients with chronic hepatitis B in West Africa. Response to: 'The gamma-glutamyl transpeptidase to platelet ratio (GPR) predicts significant liver fibrosis and cirrhosis in patients with chronic HBV infection in West Africa' by Lemoine et al (Journal article)

Stockdale, A. J., Phillips, R. O., Geretti, A. M., & Grp, H. E. P. I. K. S. (2016). The gamma-glutamyl transpeptidase to platelet ratio (GPR) shows poor correlation with transient elastography measurements of liver fibrosis in HIV-positive patients with chronic hepatitis B in West Africa. Response to: 'The gamma-glutamyl transpeptidase to platelet ratio (GPR) predicts significant liver fibrosis and cirrhosis in patients with chronic HBV infection in West Africa' by Lemoine et al. GUT, 65(5), 882-U193. doi:10.1136/gutjnl-2015-311133

DOI: 10.1136/gutjnl-2015-311133

2015

Quality of outcome reporting in phase II studies in pulmonary tuberculosis (Journal article)

Bonnett, L. J., & Davies, G. R. (2015). Quality of outcome reporting in phase II studies in pulmonary tuberculosis. TRIALS, 16. doi:10.1186/s13063-015-1050-1

DOI: 10.1186/s13063-015-1050-1

Liver Fibrosis by Transient Elastography and Virologic Outcomes After Introduction of Tenofovir in Lamivudine-Experienced Adults With HIV and Hepatitis B Virus Coinfection in Ghana (Journal article)

Stockdale, A. J., Phillips, R. O., Beloukas, A., Appiah, L. T., Chadwick, D., Bhagani, S., . . . HEPIK, H. B. I. K. (2015). Liver Fibrosis by Transient Elastography and Virologic Outcomes After Introduction of Tenofovir in Lamivudine-Experienced Adults With HIV and Hepatitis B Virus Coinfection in Ghana. CLINICAL INFECTIOUS DISEASES, 61(6), 883-891. doi:10.1093/cid/civ421

DOI: 10.1093/cid/civ421

Reported outcomes in phase II studies of newly-diagnosed pulmonary tuberculosis (Journal article)

Bonnett, L. J., & Davies, G. (2015). Reported outcomes in phase II studies of newly-diagnosed pulmonary tuberculosis. TRIALS, 16. Retrieved from http://gateway.webofknowledge.com/

Is infant exposure to antiretroviral drugs during breastfeeding quantitatively important? A systematic review and meta-analysis of pharmacokinetic studies (Journal article)

Waitt, C. J., Garner, P., Bonnett, L. J., Khoo, S. H., & Else, L. J. (2015). Is infant exposure to antiretroviral drugs during breastfeeding quantitatively important? A systematic review and meta-analysis of pharmacokinetic studies. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 70(7), 1928-1941. doi:10.1093/jac/dkv080

DOI: 10.1093/jac/dkv080

Driving Following a First-Ever Seizure (Journal article)

Bonnett, L. (2015). Driving Following a First-Ever Seizure. PracticeUpdate. Retrieved from http://www.practiceupdate.com/

Pinning Down an Acceptable Seizure Risk While Driving (Journal article)

Bonnett, L. (2015). Pinning Down an Acceptable Seizure Risk While Driving. PracticeUpdate. Retrieved from http://www.practiceupdate.com/

Quality-of-life benefits of catheter ablation of persistent atrial fibrillation: a reanalysis of data from the SARA study (Journal article)

Wynn, G. J., Das, M., Bonnett, L. J., & Gupta, D. (2015). Quality-of-life benefits of catheter ablation of persistent atrial fibrillation: a reanalysis of data from the SARA study. EUROPACE, 17(2), 222-224. doi:10.1093/europace/euu154

DOI: 10.1093/europace/euu154

A Novel Marker to Predict Early Recurrence After Atrial Fibrillation Ablation: The Ablation Effectiveness Quotient (Journal article)

Wynn, G. J., Das, M., Bonnett, L. J., Hall, M. C. S., Snowdon, R. L., Waktare, J. E. P., . . . Gupta, D. (2015). A Novel Marker to Predict Early Recurrence After Atrial Fibrillation Ablation: The Ablation Effectiveness Quotient. JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY, 26(4), 397-403. doi:10.1111/jce.12618

DOI: 10.1111/jce.12618

Reported outcomes in phase II studies of newly-diagnosed pulmonary tuberculosis. (Journal article)

Bonnett, L. J., & Davies, G. (2015). Reported outcomes in phase II studies of newly-diagnosed pulmonary tuberculosis.. Trials, 16(Suppl 1), P7. doi:10.1186/1745-6215-16-S1-P7

DOI: 10.1186/1745-6215-16-S1-P7

2014

Efficacy of Catheter Ablation for Persistent Atrial Fibrillation A Systematic Review and Meta-Analysis of Evidence From Randomized and Nonrandomized Controlled Trials (Journal article)

Wynn, G. J., Das, M., Bonnett, L. J., Panikker, S., Wong, T., & Gupta, D. (2014). Efficacy of Catheter Ablation for Persistent Atrial Fibrillation A Systematic Review and Meta-Analysis of Evidence From Randomized and Nonrandomized Controlled Trials. CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY, 7(5), 841-U149. doi:10.1161/CIRCEP.114.001759

DOI: 10.1161/CIRCEP.114.001759

External Validation of a Prognostic Model for Seizure Recurrence Following a First Unprovoked Seizure and Implications for Driving (vol 9, e99063, 2014) (Journal article)

Bonnett, L. J., Marson, A. G., Johnson, A., Kim, L., & Sander, J. W. (2014). External Validation of a Prognostic Model for Seizure Recurrence Following a First Unprovoked Seizure and Implications for Driving (vol 9, e99063, 2014). PLOS ONE, 9(11). doi:10.1371/journal.pone.0113327

DOI: 10.1371/journal.pone.0113327

FIRST, DO NO HARM. IMPROVING SAFETY IN CATHETER ABLATION FOR ATRIAL FIBRILLATION: A PROSPECTIVE STUDY OF THE USE OF ULTRASOUND TO GUIDE VASCULAR ACCESS (Conference Paper)

Wynn, G., Haq, I., Hung, J., Bonnett, L., Webber, M., Das, M., . . . Gupta, D. (2014). FIRST, DO NO HARM. IMPROVING SAFETY IN CATHETER ABLATION FOR ATRIAL FIBRILLATION: A PROSPECTIVE STUDY OF THE USE OF ULTRASOUND TO GUIDE VASCULAR ACCESS. In HEART Vol. 100 (pp. A5-A6). doi:10.1136/heartjnl-2014-306118.11

DOI: 10.1136/heartjnl-2014-306118.11

THE ABLATION EFFECTIVENESS QUOTIENT: A NOVEL MARKER TO PREDICT THE SUCCESS OF ATRIAL FIBRILLATION ABLATION (Conference Paper)

Wynn, G., Das, M., Bonnett, L., Hall, M., Snowdon, R., Waktare, J., . . . Gupta, D. (2014). THE ABLATION EFFECTIVENESS QUOTIENT: A NOVEL MARKER TO PREDICT THE SUCCESS OF ATRIAL FIBRILLATION ABLATION. In HEART Vol. 100 (pp. A6-A7). doi:10.1136/heartjnl-2014-306118.13

DOI: 10.1136/heartjnl-2014-306118.13

A comprehensive functional and clinical analysis of ABCC2 and its impact on treatment response to carbamazepine (Journal article)

Raedisch, S., Dickens, D., Lang, T., Bonnett, L., Arlanov, R., Johnson, M. R., . . . Pirmohamed, M. (2014). A comprehensive functional and clinical analysis of ABCC2 and its impact on treatment response to carbamazepine. PHARMACOGENOMICS JOURNAL, 14(5), 481-487. doi:10.1038/tpj.2014.5

DOI: 10.1038/tpj.2014.5

External Validation of a Prognostic Model for Seizure Recurrence Following a First Unprovoked Seizure and Implications for Driving (Journal article)

Bonnett, L. J., Marson, A. G., Johnson, A., Kim, L., Sander, J. W., Lawn, N., . . . Smith, C. T. (2014). External Validation of a Prognostic Model for Seizure Recurrence Following a First Unprovoked Seizure and Implications for Driving. PLOS ONE, 9(6). doi:10.1371/journal.pone.0099063

DOI: 10.1371/journal.pone.0099063

Improving Safety in Catheter Ablation for Atrial Fibrillation: A Prospective Study of the Use of Ultrasound to Guide Vascular Access (Journal article)

Wynn, G. J., Haq, I., Hung, J., Bonnett, L. J., Lewis, G., Webber, M., . . . Gupta, D. (2014). Improving Safety in Catheter Ablation for Atrial Fibrillation: A Prospective Study of the Use of Ultrasound to Guide Vascular Access. JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY, 25(7), 680-685. doi:10.1111/jce.12404

DOI: 10.1111/jce.12404

The European Heart Rhythm Association symptom classification for atrial fibrillation: validation and improvement through a simple modification (Journal article)

Wynn, G. J., Todd, D. M., Webber, M., Bonnett, L., McShane, J., Kirchhof, P., & Gupta, D. (2014). The European Heart Rhythm Association symptom classification for atrial fibrillation: validation and improvement through a simple modification. EUROPACE, 16(7), 965-972. doi:10.1093/europace/eut395

DOI: 10.1093/europace/eut395

Thiopurine monitoring in children with inflammatory bowel disease: a systematic review (Journal article)

Konidari, A., Anagnostopoulos, A., Bonnett, L. J., Pirmohamed, M., & El-Matary, W. (2014). Thiopurine monitoring in children with inflammatory bowel disease: a systematic review. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 78(3), 467-476. doi:10.1111/bcp.12365

DOI: 10.1111/bcp.12365

Time to 12-month remission and treatment failure for generalised and unclassified epilepsy (Journal article)

Bonnett, L. J., Smith, C. T., Smith, D., Williamson, P. R., Chadwick, D., & Marson, A. G. (2014). Time to 12-month remission and treatment failure for generalised and unclassified epilepsy. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 85(6), 603-610. doi:10.1136/jnnp-2013-306040

DOI: 10.1136/jnnp-2013-306040

Treatment outcome after failure of a first antiepileptic drug (Journal article)

Bonnett, L. J., Smith, C. T., Donegan, S., & Marson, A. G. (2014). Treatment outcome after failure of a first antiepileptic drug. NEUROLOGY, 83(6), 552-560. doi:10.1212/WNL.0000000000000673

DOI: 10.1212/WNL.0000000000000673

2013

External validation of a prognostic index (Conference Paper)

Bonnett, L. J., Marson, A. G., Johnson, A., Kim, L., Sander, J. W., Lawn, N., . . . Tudur Smith, C. (2013). External validation of a prognostic index. In Trials Vol. 14 (pp. P43). Retrieved from http://www.trialsjournal.com/content/14/S1/P43

External validation of a prognostic index. (Journal article)

Bonnett, L., Marson, A., Johnson, T., Kim, L., Sander, L., Lawn, N., . . . Smith, C. T. (2013). External validation of a prognostic index.. Trials, 14(Suppl 1), P43. doi:10.1186/1745-6215-14-S1-P43

DOI: 10.1186/1745-6215-14-S1-P43

PROGNOSTIC FACTORS FOR TIME TO TREATMENT FAILURE AND TIME TO 12 MONTH REMISSION FOR PATIENTS WITH GENERALISED EPILEPSY: POST HOC AND SUBGROUP ANALYSES OF SANAD (Conference Paper)

Bonnett, L. J., Smith, C. T., Smith, D., Williamson, P., Chadwick, D., & Marson, A. (2012). PROGNOSTIC FACTORS FOR TIME TO TREATMENT FAILURE AND TIME TO 12 MONTH REMISSION FOR PATIENTS WITH GENERALISED EPILEPSY: POST HOC AND SUBGROUP ANALYSES OF SANAD. In EPILEPSIA Vol. 53 (pp. 77). Retrieved from http://gateway.webofknowledge.com/

Short- versus long-term outcomes after treatment for tuberculosis. (Journal article)

Bonnett, L., & Davies, G. (2013). Short- versus long-term outcomes after treatment for tuberculosis.. Trials, 14(Suppl 1), P44. doi:10.1186/1745-6215-14-S1-P44

DOI: 10.1186/1745-6215-14-S1-P44

2012

Prognostic factors for time to treatment failure and time to 12 months of remission for patients with focal epilepsy: post-hoc, subgroup analyses of data from the SANAD trial (Journal article)

Bonnett, L., Smith, C. T., Smith, D., Williamson, P., Chadwick, D., & Marson, A. G. (2012). Prognostic factors for time to treatment failure and time to 12 months of remission for patients with focal epilepsy: post-hoc, subgroup analyses of data from the SANAD trial. LANCET NEUROLOGY, 11(4), 331-340. doi:10.1016/S1474-4422(12)70018-2

DOI: 10.1016/S1474-4422(12)70018-2

Prognostic factors for time to treatment failure and time to 12 month remission for patients with generalised epilepsy: post-hoc and subgroup analyses of SANAD (Conference Paper)

Bonnett, L. J., Tudur Smith, C., Smith, D., Williamson, P. R., Chadwick, D., & Marson, A. G. (2012). Prognostic factors for time to treatment failure and time to 12 month remission for patients with generalised epilepsy: post-hoc and subgroup analyses of SANAD. In 10th European Congress on Epileptology (pp. 104). London: ILAE.

2011

Child development following in utero exposure Levetiracetam vs sodium valproate (Journal article)

Shallcross, R., Bromley, R. L., Irwin, B., Bonnett, L. J., Morrow, J., Baker, G. A., . . . Register, U. K. E. P. (2011). Child development following in utero exposure Levetiracetam vs sodium valproate. NEUROLOGY, 76(4), 383-389. doi:10.1212/WNL.0b013e3182088297

DOI: 10.1212/WNL.0b013e3182088297

Seizure recurrence after antiepileptic drug withdrawal and the implications for driving: further results from the MRC Antiepileptic Drug Withdrawal Study and a systematic review (Journal article)

Bonnett, L. J., Shukralla, A., Tudur-Smith, C., Williamson, P. R., & Marson, A. G. (2011). Seizure recurrence after antiepileptic drug withdrawal and the implications for driving: further results from the MRC Antiepileptic Drug Withdrawal Study and a systematic review. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 82(12), 1328-1333. doi:10.1136/jnnp.2010.222885

DOI: 10.1136/jnnp.2010.222885

Simulation study - handling missing covariates in the context of external validation. (Conference Paper)

Bonnett, L. J., Marson, T. G., Williamson, P. R., & Tudur-Smith, C. (2011). Simulation study - handling missing covariates in the context of external validation.. In Trials Vol. 12 (pp. A62). doi:10.1186/1745-6215-12-S1-A62

DOI: 10.1186/1745-6215-12-S1-A62

2010

Risk of recurrence after a first seizure and implications for driving: further analysis of the Multicentre study of early Epilepsy and Single Seizures (Journal article)

Bonnett, L. J., Tudur-Smith, C., Williamson, P. R., & Marson, A. G. (2010). Risk of recurrence after a first seizure and implications for driving: further analysis of the Multicentre study of early Epilepsy and Single Seizures. BRITISH MEDICAL JOURNAL, 341. doi:10.1136/bmj.c6477

DOI: 10.1136/bmj.c6477

2009

PROGNOSTIC FACTORS FOR 12-MONTH REMISSION (Conference Paper)

Bonnett, L., Tudur-Smith, C., Williamson, P., & Marson, T. (2009). PROGNOSTIC FACTORS FOR 12-MONTH REMISSION. In EPILEPSIA Vol. 50 (pp. 110). Retrieved from http://gateway.webofknowledge.com/

Using gene subsets in the assessment of microarray data quality for time course experiments (Journal article)

Guan, S. L., Bonnett, L., & Brettschneider, J. (2009). Using gene subsets in the assessment of microarray data quality for time course experiments. CRISM Research Paper. Retrieved from http://www2.warwick.ac.uk/fac/sci/statistics/crism/research/2009/paper09-24

2008

Prognostic Factors for 12-Month Remission (Conference Paper)

Bonnett, L. J. (2008). Prognostic Factors for 12-Month Remission. In Workshop on statistical modeling of epilepsy data (pp. 2). Coventry: University of Warwick.