Dr James Wilson PhD

Lecturer Molecular and Clinical Cancer Medicine

  • +44 (0)151 794 8871

    Publications

    2012

    mRNA 3 ' Tagging Is Induced by Nonsense-Mediated Decay and Promotes Ribosome Dissociation (Journal article)

    Morozov, I. Y., Jones, M. G., Gould, P. D., Crome, V., Wilson, J. B., Hall, A. J. W., . . . Caddick, M. X. (2012). mRNA 3 ' Tagging Is Induced by Nonsense-Mediated Decay and Promotes Ribosome Dissociation. MOLECULAR AND CELLULAR BIOLOGY, 32(13), 2585-2595. doi:10.1128/MCB.00316-12

    DOI: 10.1128/MCB.00316-12

    2011

    Functional and physical interaction between the mismatch repair and FA-BRCA pathways (Journal article)

    Williams, S. A., Wilson, J. B., Clark, A. P., Mitson-Salazar, A., Tomashevski, A., Ananth, S., . . . Kupfer, G. M. (2011). Functional and physical interaction between the mismatch repair and FA-BRCA pathways. Human Molecular Genetics, 20(22), 4395-4410. doi:10.1093/hmg/ddr366

    DOI: 10.1093/hmg/ddr366

    2010

    Several tetratricopeptide repeat (TPR) motifs of FANCG are required for assembly of the BRCA2/D1-D2-G-X3 complex, FANCD2 monoubiquitylation and phleomycin resistance (Journal article)

    Wilson, J. B., Blom, E., Cunningham, R., Xiao, Y., Kupfer, G. M., & Jones, N. J. (2010). Several tetratricopeptide repeat (TPR) motifs of FANCG are required for assembly of the BRCA2/D1-D2-G-X3 complex, FANCD2 monoubiquitylation and phleomycin resistance. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 689(1-2), 12-20. doi:10.1016/j.mrfmmm.2010.04.003

    DOI: 10.1016/j.mrfmmm.2010.04.003

    Significance of the Fanconi Anemia FANCD2 Protein in Sporadic and Metastatic Human Breast Cancer (Journal article)

    Rudland, P. S., Platt-Higgins, A. M., Davies, L. M., Rudland, S. D. S., Wilson, J. B., Aladwani, A., . . . Jones, N. J. (2010). Significance of the Fanconi Anemia FANCD2 Protein in Sporadic and Metastatic Human Breast Cancer. AMERICAN JOURNAL OF PATHOLOGY, 176(6), 2935-2947. doi:10.2353/ajpath.2010.090779

    DOI: 10.2353/ajpath.2010.090779

    2009

    Optimization of the comet assay for the sensitive detection of PUVA-induced DNA interstrand cross-links (Journal article)

    Wu, J. H., Wilson, J. B., Wolfreys, A. M., Scott, A., & Jones, N. J. (n.d.). Optimization of the comet assay for the sensitive detection of PUVA-induced DNA interstrand cross-links. Mutagenesis, 24(2), 173-181. doi:10.1093/mutage/gen068

    DOI: 10.1093/mutage/gen068

    ATR-dependent phosphorylation of FANCA on serine 1449 after DNA damage is important for FA pathway function (Journal article)

    Collins, N. B., Wilson, J. B., Bush, T., Thomashevski, A., Roberts, K. J., Jones, N. J., & Kupfer, G. M. (2009). ATR-dependent phosphorylation of FANCA on serine 1449 after DNA damage is important for FA pathway function. Blood, 113(10), 2181-2190. doi:10.1182/blood-2008-05-154294

    DOI: 10.1182/blood-2008-05-154294

    Fanconi Anemia Complementation Group FANCD2 Protein Serine 331 Phosphorylation Is Important for Fanconi Anemia Pathway Function and BRCA2 Interaction (Journal article)

    Zhi, G., Wilson, J. B., Chen, X., Krause, D. S., Xiao, Y., Jones, N. J., & Kupfer, G. M. (2009). Fanconi Anemia Complementation Group FANCD2 Protein Serine 331 Phosphorylation Is Important for Fanconi Anemia Pathway Function and BRCA2 Interaction. Cancer Research, 69(22), 8775-8783. doi:10.1158/0008-5472.can-09-2312

    DOI: 10.1158/0008-5472.can-09-2312

    2008

    FANCG promotes formation of a newly identified protein complex containing BRCA2, FANCD2 and XRCC3 (Journal article)

    Wilson, J. B., Yamamoto, K., Marriott, A. S., Hussain, S., Sung, P., Hoatlin, M. E., . . . Jones, N. J. (2008). FANCG promotes formation of a newly identified protein complex containing BRCA2, FANCD2 and XRCC3. ONCOGENE, 27(26), 3641-3652. doi:10.1038/sj.onc.1211034

    DOI: 10.1038/sj.onc.1211034

    2006

    Tetratricopeptide-motif-mediated interaction of FANCG with recombination proteins XRCC3 and BRCA2 (Journal article)

    Hussain, S., Wilson, J. B., Blom, E., Thompson, L. H., Sung, P., Gordon, S. M., . . . Jones, N. J. (2006). Tetratricopeptide-motif-mediated interaction of FANCG with recombination proteins XRCC3 and BRCA2. DNA REPAIR, 5(5), 629-640. doi:10.1016/j.dnarep.2006.02.007

    DOI: 10.1016/j.dnarep.2006.02.007

    2005

    New insights into the Fanconi anemia pathway from an isogenic FancG hamster CHO mutant (Journal article)

    Tebbs, R. S., Hinz, J. M., Yamada, N. A., Wilson, J. B., Salazar, E. P., Thomas, C. B., . . . Thompson, L. H. (2005). New insights into the Fanconi anemia pathway from an isogenic FancG hamster CHO mutant. DNA Repair, 4, 11-22. Retrieved from http://www.sciencedirect.com/

    2004

    Direct interaction of FANCD2 with BRCA2 in DNA damage response pathways (Journal article)

    Hussain, S., Wilson, J. B., Medhurst, A. L., Hejna, J., Witt, E., Ananth, S., . . . Mathew, C. G. (2004). Direct interaction of FANCD2 with BRCA2 in DNA damage response pathways. HUMAN MOLECULAR GENETICS, 13(12), 1241-1248. doi:10.1093/hmg/ddh135

    DOI: 10.1093/hmg/ddh135

    FANCG Is Phosphorylated at Serines 383 and 387 during Mitosis (Journal article)

    Mi, J., Qiao, F., Wilson, J. B., High, A. A., Schroeder, M. J., Stukenberg, P. T., . . . Kupfer, G. M. (2004). FANCG Is Phosphorylated at Serines 383 and 387 during Mitosis. Molecular and Cellular Biology, 24(19), 8576-8585. doi:10.1128/mcb.24.19.8576-8585.2004

    DOI: 10.1128/mcb.24.19.8576-8585.2004

    Phosphorylation of Fanconi Anemia (FA) Complementation Group G Protein, FANCG, at Serine 7 Is Important for Function of the FA Pathway (Journal article)

    Qiao, F., Mi, J., Wilson, J. B., Zhi, G., Bucheimer, N. R., Jones, N. J., & Kupfer, G. M. (2004). Phosphorylation of Fanconi Anemia (FA) Complementation Group G Protein, FANCG, at Serine 7 Is Important for Function of the FA Pathway. Journal of Biological Chemistry, 279(44), 46035-46045. doi:10.1074/jbc.m408323200

    DOI: 10.1074/jbc.m408323200

    2001

    The Chinese hamster FANCG/XRCC9 mutant NM3 fails to express the monoubiquitinated form of the FANCD2 protein, is hypersensitive to a range of DNA damaging agents and exhibits a normal level of spontaneous sister chromatid exchange (Journal article)

    Wilson, J. B., Johnson, M. A., Stuckert, A. P., Trueman, K. L., May, S., Bryant, P. E., . . . Jones, N. J. (2001). The Chinese hamster FANCG/XRCC9 mutant NM3 fails to express the monoubiquitinated form of the FANCD2 protein, is hypersensitive to a range of DNA damaging agents and exhibits a normal level of spontaneous sister chromatid exchange. Carcinogenesis, 22(12), 1939-1946. doi:10.1093/carcin/22.12.1939

    DOI: 10.1093/carcin/22.12.1939

    • +44 (0)151 794 8871