Professor Daniel Perry MB, ChB (Hons), FRCS (Tr&Orth), PhD

Professor & Honorary Consultant Orthopaedic Surgeon (Alder Hey Children's Hospital) Women's & Children's Health

Research

Research Overview

CLINICAL TRIALS - He has a portfolio of international clinical trials. He has over >£30m (USD $40 million) in research income, including as Chief Investigator on the NIHR British Orthopaedic Surgery Surveillance (BOSS) Study (Paediatric Hip Disease), NIHR FORCE Study (Simple Wrist Fractures), NIHR SCIENCE Study (Medial Epicondyle Fractures), NIHR CRAFFT Study (Severe Wrist Fractures), NIHR BigBOSS Study (Hip Disease), NIHR BASIS Study (Scoliosis) and the NIHR Odd SOCKS Study (Ankle Fractures). He is currently working Lurie Children’s Hospital in Chicago (USA) to reproduce the UK studies throughout North America, with an NIH R01 grant recently awarded.

INNOVATION – He works in collaboration with engineers and industry to develop new diagnostic tools; examples include the identification and monitoring of hip migration amongst children with Cerebral Palsy (Manchester University), and the detection of hip dysplasia amongst babies (Oxford University, Liverpool John Moores University and Industry).

RESEARCH PROFESSORSHIP – Professor Perry is the first orthopaedic surgeon to have been awarded a prestigious NIHR Research Professorship. The focus is to develop a nationwide platform trial to optimise the detection and treatment of developmental hip dysplasia amongst babies – thereby combining his passion for both clinical trials and innovation.

CLINICAL WORK - He works at Alder Hey Children’s Hospital and specialises in Children’s Hip Disease and Trauma. He trained in Liverpool and Warwick, before completing a fellowship at SickKids Hospital, Toronto, Canada.

OUTPUTS - He has published over 150 peer-reviewed papers – including in original research articles in the Lancet, JAMA and BMJ. For his research has been awarded both the Hunterian Professorship by the Royal College of Surgeons of England, the Robert Jones Gold Medal from the British Orthopaedic Association and an Honorary Fellowship from the Royal College of Surgeons of Edinburgh.

PATIENT INVOLVEMENT – Professor Perry has a thriving group of children and families who contribute to his research by advising on the design and conduct of studies. With this group, he has developed the way that research materials are delivered to families – with cartoons now playing a central feature in how studies are explained to families, and how the results are disseminated - i.e. www.FORCEstudy.org

RESEARCH STUDENTS AND STAFF - Dan supervises several PhD students, and works with a broad team of biostatisticians, health economists, trial managers, data specialists and engineers.

A full list of active study websites:

www.FORCEstudy.org
www.CRAFFTstudy.org
www.SCIENCEstudy.org
www.BASISstudy.org
www.ODDsocks.org
www.BigBOSSstudy.org
www.PICbone.com

See my online teaching and videos:

https://vimeo.com/user68840692

Children's Orthopaedic Surgery

Clinical Trials

Big Data

Research Grants

IMPACCT – Infrastructure for Musculoskeletal Pediatric Acute Care Clinical Trials

NATIONAL INSTITUTES OF HEALTH (USA)

September 2021 - August 2024

Overcoming unplanned variation in children’s health: Maximising the safety and effectiveness of orthopaedic care for children through better evidence NIHR Research Professorship for Dan Perry (OUCH)

DEPARTMENT OF HEALTH & SOCIAL CARE (UK)

December 2021 - November 2026

SHINE: Screening the Hips In Newborns - The use of a handheld device to detect the transmission of vibration across the hip joint to enhance the detection of developmental hip dysplasia in babies

ARTHRITIS RESEARCH UK

November 2016 - July 2020

ORCHID Study: Outcomes Research in Children's Hip Disease

ARTHRITIS RESEARCH UK

October 2016 - August 2020

British Orthopaedic SCFE Surgery (BOSS) Study Investigating Slipped Capital Femoral Epiphysis (SCFE) as a childhood precursor to osteoarthritis

ALDER HEY CHILDREN'S NHS FOUNDATION TRUST (UK), DEPARTMENT OF HEALTH & SOCIAL CARE (UK)

March 2015 - May 2020

Establishing a research agenda including ‘trial balance’ and ‘community equipoise’ in Perthes’ disease of the hip: A Qualitative Study

PERTHES ASSOCIATION (UK)

May 2015 - May 2017

Developing the feasibility of a clinical trial in Perthes' Disease

PERTHES ASSOCIATION (UK)

June 2015 - March 2020

Investigating the UK epidemiology of slipped capital femoral epiphysis: A population based descriptive and case-control study

THE ACADEMY OF MEDICAL SCIENCES (UK)

March 2015 - May 2017

Understanding the aetiology of Legg-Calve-Perthes disease: A national investigation of geographical and longitudinal trends using the General Practice Research Database

BRITISH MEDICAL ASSOCIATION (UK)

September 2009 - August 2012