2024
Smith, E. M. D., Aggarwal, A., Ainsworth, J., Al-Abadi, E., Avcin, T., Bortey, L., . . . Marks, S. D. (2024). Defining remission in childhood-onset lupus: PReS-endorsed consensus definitions by an international task force.. Clinical immunology (Orlando, Fla.), 110214. doi:10.1016/j.clim.2024.110214DOI: 10.1016/j.clim.2024.110214
Renaudineau, Y., Charras, A., Natoli, V., Fusaro, M., Smith, E. M. D., Beresford, M. W., . . . UK jSLE Cohort Study. (2024). Type I interferon associated epistasis may contribute to early disease-onset and high disease activity in juvenile-onset lupus.. Clinical immunology (Orlando, Fla.), 262, 110194. doi:10.1016/j.clim.2024.110194DOI: 10.1016/j.clim.2024.110194
Charras, A., Hofmann, S. R., Cox, A., Schulze, F., Russ, S., Northey, S., . . . Hedrich, C. M. (2024). P2RX7 gene variants associate with altered inflammasome assembly and reduced pyroptosis in chronic nonbacterial osteomyelitis (CNO).. Journal of autoimmunity, 144, 103183. doi:10.1016/j.jaut.2024.103183DOI: 10.1016/j.jaut.2024.103183
Chapter 11 Approaches to autoimmune diseases using epigenetic therapy (Chapter)
Hedrich, C. M. (2024). Chapter 11 Approaches to autoimmune diseases using epigenetic therapy. In Epigenetics in Human Disease (pp. 413-431). Elsevier. doi:10.1016/b978-0-443-18661-5.00024-5DOI: 10.1016/b978-0-443-18661-5.00024-5
2023
Li, S. W. S., Roberts, E., & Hedrich, C. (2023). Treatment and monitoring of SAPHO syndrome: a systematic review.. RMD open, 9(4), e003688. doi:10.1136/rmdopen-2023-003688DOI: 10.1136/rmdopen-2023-003688
Updates zur chronisch nichtbakteriellen Osteomyelitis (CNO) (Journal article)
Hahn, G., & Hedrich, C. M. (2023). Updates zur chronisch nichtbakteriellen Osteomyelitis (CNO). Arthritis und Rheuma, 43(06), 393-402. doi:10.1055/a-2198-2295DOI: 10.1055/a-2198-2295
Carlsson, E., Cowell-McGlory, T., & Hedrich, C. M. (2023). cAMP responsive element modulator α promotes effector T cells in systemic autoimmune diseases. IMMUNOLOGY. doi:10.1111/imm.13680DOI: 10.1111/imm.13680
Jiang, L., Qiu, W., Wang, X., Duan, X., Han, X., Yu, T., . . . Deng, G. -M. (2023). Immunoglobulin G inhibits glucocorticoid-induced osteoporosis through occupation of FcγRI.. iScience, 26(10), 107749. doi:10.1016/j.isci.2023.107749DOI: 10.1016/j.isci.2023.107749
Wu, E. Y., Oliver, M., Scheck, J., Lapidus, S., Akca, U. K., Yasin, S., . . . Zhao, Y. (2023). Feasibility of Conducting Comparative Effectiveness Research and Validation of a Clinical Disease Activity Score for Chronic Nonbacterial Osteomyelitis.. The Journal of rheumatology, 50(10), 1333-1340. doi:10.3899/jrheum.2022-1323DOI: 10.3899/jrheum.2022-1323
Late Breaking Abstract - Age and vitamin D influence airway epithelial cells response to SARS-CoV-2 infection (Conference Paper)
Sposito, F., Pennington, S., David, C., Duggan, J., Northey, S., Biagini, G., . . . Hedrich, C. (2023). Late Breaking Abstract - Age and vitamin D influence airway epithelial cells response to SARS-CoV-2 infection. In Airway cell biology and immunopathology. European Respiratory Society. doi:10.1183/13993003.congress-2023.oa4962DOI: 10.1183/13993003.congress-2023.oa4962
Sposito, F., Northey, S., Charras, A., McNamara, P. S., & Hedrich, C. M. (2023). Hypertonic saline induces inflammation in human macrophages through the NLRP1 inflammasome.. Genes and immunity. doi:10.1038/s41435-023-00218-7DOI: 10.1038/s41435-023-00218-7
Sposito, F., Pennington, S. H., A W David, C., Duggan, J., Northey, S., Biagini, G., . . . Hedrich, C. M. (2023). Age differential CD13 and interferon expression in airway epithelia affect SARS-CoV-2 infection - effects of vitamin D.. Mucosal immunology, S1933-0219(23)00064-8. doi:10.1016/j.mucimm.2023.08.002DOI: 10.1016/j.mucimm.2023.08.002
Natoli, V., Charras, A., Hahn, G., & Hedrich, C. M. (2023). Neuropsychiatric involvement in juvenile-onset systemic lupus erythematosus (jSLE). MOLECULAR AND CELLULAR PEDIATRICS, 10(1). doi:10.1186/s40348-023-00161-7DOI: 10.1186/s40348-023-00161-7
On the climate emergency and the health of our patients: comment on the article by Dellaripa et al (Journal article)
Hospach, T., Belot, A. W., Beresford, M., Dressler, F., Kallinich, T., Oommen, P. E., . . . Hedrich, C. (2023). On the climate emergency and the health of our patients: comment on the article by Dellaripa et al. ARTHRITIS & RHEUMATOLOGY, 75(8), 1493-1494. doi:10.1002/art.42483DOI: 10.1002/art.42483
David, T., Su, L., Cheng, Y., Gordon, C., Parker, B., Isenberg, D., . . . MASTERPLANS Consortium. (2023). Predictors of British Isles Lupus Assessment Group-based outcomes in patients with systemic lupus erythematosus: Analysis from the Systemic Lupus International Collaborating Clinics Inception Cohort.. Lupus, 32(9), 1043-1055. doi:10.1177/09612033231183273DOI: 10.1177/09612033231183273
Akthar, M., Nair, N., Carter, L. M., Vital, E. M., Sutton, E., McHugh, N., . . . Reynolds, J. A. (2023). Deconvolution of whole blood transcriptomics identifies changes in immune cell composition in patients with systemic lupus erythematosus (SLE) treated with mycophenolate mofetil.. Arthritis research & therapy, 25(1), 111. doi:10.1186/s13075-023-03089-5DOI: 10.1186/s13075-023-03089-5
Mohanna, M., Roberts, E., Whitty, L., Gritzfeld, J. F., Pain, C. E., Girschick, H. J., . . . Hedrich, C. M. (2023). Priorities in Chronic nonbacterial osteomyelitis (CNO) - results from an international survey and roundtable discussions. PEDIATRIC RHEUMATOLOGY, 21(1). doi:10.1186/s12969-023-00851-6DOI: 10.1186/s12969-023-00851-6
Singhal, S., Landes, C., Shukla, R., McCann, L. J., & Hedrich, C. M. (2023). Classification and management strategies for paediatric chronic nonbacterial osteomyelitis and chronic recurrent multifocal osteomyelitis.. Expert review of clinical immunology, 1-16. doi:10.1080/1744666x.2023.2218088DOI: 10.1080/1744666x.2023.2218088
Hedrich, C. M., Beresford, M. W., Dedeoglu, F., Hahn, G., Hofmann, S. R., Jansson, A. F., . . . Girschick, H. J. (2023). Gathering expert consensus to inform a proposed trial in chronic nonbacterial osteomyelitis (CNO). CLINICAL IMMUNOLOGY, 251. doi:10.1016/j.clim.2023.109344DOI: 10.1016/j.clim.2023.109344
OP0100 DNA METHYLATION PATTERNS IN CD4+ T CELLS DISCERN SKIN PSORIASIS FROM PSORIATIC ARTHRITIS (Conference Paper)
Natoli, V., Charras, A., Hofmann, S., Northey, S., Russ, S., Schulze, F., . . . Hedrich, C. (2023). OP0100 DNA METHYLATION PATTERNS IN CD4+ T CELLS DISCERN SKIN PSORIASIS FROM PSORIATIC ARTHRITIS. In Scientific Abstracts. BMJ Publishing Group Ltd and European League Against Rheumatism. doi:10.1136/annrheumdis-2023-eular.4069DOI: 10.1136/annrheumdis-2023-eular.4069
Smith, E. M. D., Aggarwal, A., Ainsworth, J., Al-Abadi, E., Avcin, T., Bortey, L., . . . Beresford, M. W. (2023). Towards development of treat to target (T2T) in childhood-onset systemic lupus erythematosus: PReS-endorsed overarching principles and points-to-consider from an international task force. ANNALS OF THE RHEUMATIC DISEASES, 82(6), 788-798. doi:10.1136/ard-2022-223328DOI: 10.1136/ard-2022-223328
PReS-endorsed international childhood lupus T2T task force definition of childhood lupus low disease activity state (cLLDAS) (Journal article)
Smith, E. M. D., Aggarwal, A., Ainsworth, J., Al-Abadi, E., Avcin, T., Bortey, L., . . . Beresford, M. W. (2023). PReS-endorsed international childhood lupus T2T task force definition of childhood lupus low disease activity state (cLLDAS). CLINICAL IMMUNOLOGY, 250. doi:10.1016/j.clim.2023.109296DOI: 10.1016/j.clim.2023.109296
OA39 Development of a Childhood Lupus Low Disease Activity State definition: recommendations from the International Childhood Lupus Treat-to-Target Task Force (Journal article)
Smith, E. M. D., Aggarwal, A., Ainsworth, J., Al-Abadi, E., Avcin, T., Bortey, L., . . . Beresford, M. W. (2023). OA39 Development of a Childhood Lupus Low Disease Activity State definition: recommendations from the International Childhood Lupus Treat-to-Target Task Force. Rheumatology, 62(Supplement_2). doi:10.1093/rheumatology/kead104.038DOI: 10.1093/rheumatology/kead104.038
Garau, J., Charras, A., Varesio, C., Orcesi, S., Dragoni, F., Galli, J., . . . Hedrich, C. M. (2023). Altered DNA methylation and gene expression predict disease severity in patients with Aicardi-Goutieres syndrome. CLINICAL IMMUNOLOGY, 249. doi:10.1016/j.clim.2023.109299DOI: 10.1016/j.clim.2023.109299
Current views on lupus in children (Journal article)
Smith, E. M. D., Lythgoe, H., & Hedrich, C. M. (2023). Current views on lupus in children. CURRENT OPINION IN RHEUMATOLOGY, 35(2), 68-81. doi:10.1097/BOR.0000000000000913DOI: 10.1097/BOR.0000000000000913
Charras, A., Haldenby, S., Smith, E. M. D., Egbivwie, N., Olohan, L., Kenny, J. G., . . . Hedrich, C. M. (2023). Panel sequencing links rare, likely damaging gene variants with distinct clinical phenotypes and outcomes in juvenile-onset SLE. RHEUMATOLOGY, 62(SI2), SI210-SI225. doi:10.1093/rheumatology/keac275DOI: 10.1093/rheumatology/keac275
Approaches to autoimmune diseases using epigenetic therapy (Chapter)
Hedrich, C. M. (2024). Approaches to autoimmune diseases using epigenetic therapy. In Epigenetics in Human Disease (pp. 413-431). Elsevier. doi:10.1016/b978-0-443-18661-5.00024-5DOI: 10.1016/b978-0-443-18661-5.00024-5
Natoli, V., Charras, A., Hofmann, S. R., Northey, S., Russ, S., Schulze, F., . . . Hedrich, C. M. (n.d.). DNA methylation patterns in CD4+ T-cells separate psoriasis patients from healthy controls, and skin psoriasis from psoriatic arthritis. Frontiers in Immunology, 14. doi:10.3389/fimmu.2023.1245876DOI: 10.3389/fimmu.2023.1245876
Jiju, P., Matalliotakis, M., Lane, S., Wong, W., Hedrich, C. M., & Pain, C. E. (2023). Demographic, clinical and laboratory differences between paediatric acute COVID-19 and PIMS-TS-results from a single centre study in the UK.. Frontiers in pediatrics, 11, 1219654. doi:10.3389/fped.2023.1219654DOI: 10.3389/fped.2023.1219654
Renaudineau, Y., Muller, S., Hedrich, C. M., Chauveau, D., Belliere, J., De Almeida, S., . . . Bost, C. (2023). Immunological and translational key challenges in systemic lupus erythematosus: A symposium update. In JOURNAL OF TRANSLATIONAL AUTOIMMUNITY Vol. 6. doi:10.1016/j.jtauto.2023.100199DOI: 10.1016/j.jtauto.2023.100199
Gavan, S. P., Bruce, I. N., Payne, K., & MASTERPLANS Consortium. (2023). Valuing Health Gain from Composite Response Endpoints for Multisystem Diseases.. Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research, 26(1), 115-122. doi:10.1016/j.jval.2022.07.001DOI: 10.1016/j.jval.2022.07.001
2022
Feasibility of Conducting Comparative Effectiveness Research and Validation of a Clinical Disease Activity Score for Chronic Nonbacterial Osteomyelitis (Preprint)
DOI: 10.1101/2022.10.03.22280351
Hypertonic saline triggers inflammatory responses in THP-1 derived macrophages (Conference Paper)
Sposito, F., Northey, S., Mcnamara, P., & Hedrich, C. (2022). Hypertonic saline triggers inflammatory responses in THP-1 derived macrophages. In EUROPEAN RESPIRATORY JOURNAL Vol. 60. doi:10.1183/13993003.congress-2022.2490DOI: 10.1183/13993003.congress-2022.2490
Smith, E. M. D., Tharmaratnam, K., Al-Abadi, E., Armon, K., Bailey, K., Brennan, M., . . . Beresford, M. W. (n.d.). Attainment of low disease activity and remission targets reduces the risk of severe flare and new damage in childhood lupus. Rheumatology. doi:10.1093/rheumatology/keab915DOI: 10.1093/rheumatology/keab915
678 Damaging variants in P2X7R associate with Chronic Nonbacterial Osteomyelitis (CNO) (Conference Paper)
Charras, A., Hofmann, S. R., Cox, A., Schulze, F., Russ, S., Hartmann, H., . . . Hedrich, C. M. (2022). 678 Damaging variants in P2X7R associate with Chronic Nonbacterial Osteomyelitis (CNO). In British Society for Rheumatology. BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health. doi:10.1136/archdischild-2022-rcpch.421DOI: 10.1136/archdischild-2022-rcpch.421
883 Altered DNA methylation patterns in monocytes from Chronic Nonbacterial Osteomyelitis (CNO) patients remain after induction of remission (Conference Paper)
Carlsson, E., Charras, A., Duffy, G., Beresford, M., Girschick, H., Morbach, H., & Hedrich, C. (2022). 883 Altered DNA methylation patterns in monocytes from Chronic Nonbacterial Osteomyelitis (CNO) patients remain after induction of remission. In British Society for Rheumatology. BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health. doi:10.1136/archdischild-2022-rcpch.423DOI: 10.1136/archdischild-2022-rcpch.423
Smith, E. M. D., Egbivwie, N., Jorgensen, A. L., Ciurtin, C., Al-Abadi, E., Armon, K., . . . Hedrich, C. M. (2022). Real world treatment of juvenile-onset systemic lupus erythematosus: Data from the UK JSLE cohort study. CLINICAL IMMUNOLOGY, 239. doi:10.1016/j.clim.2022.109028DOI: 10.1016/j.clim.2022.109028
WS12.06 Hypertonic saline triggers inflammatory responses in human macrophages (Journal article)
Sposito, F., Northey, S., McNamara, P. S., & Hedrich, C. M. (2022). WS12.06 Hypertonic saline triggers inflammatory responses in human macrophages. Journal of Cystic Fibrosis, 21, S24. doi:10.1016/s1569-1993(22)00224-7DOI: 10.1016/s1569-1993(22)00224-7
McDonald, S., Yiu, S., Su, L., Gordon, C., Truman, M., Lisk, L., . . . MASTERPLANS Consortium. (2022). Predictors of treatment response in a lupus nephritis population: lessons from the Aspreva Lupus Management Study (ALMS) trial.. Lupus science & medicine, 9(1), e000584. doi:10.1136/lupus-2021-000584DOI: 10.1136/lupus-2021-000584
RIP2-deficiency induces inflammation in response to SV40 Large T induced genotoxic stress through altered ROS homeostasis (Journal article)
Kapplusch, F., Schulze, F., Reinke, S., Russ, S., Linge, M., Kulling, F., . . . Hofmann, S. R. (2022). RIP2-deficiency induces inflammation in response to SV40 Large T induced genotoxic stress through altered ROS homeostasis. CLINICAL IMMUNOLOGY, 238. doi:10.1016/j.clim.2022.108998DOI: 10.1016/j.clim.2022.108998
Schnabel, A., Nashawi, M., Anderson, C., Felsenstein, S., Lamoudi, M., Poole-Cowley, J., . . . Hedrich, C. M. (2022). TNF-inhibitors or bisphosphonates in chronic nonbacterial osteomyelitis? -Results of an international retrospective multicenter study. CLINICAL IMMUNOLOGY, 238. doi:10.1016/j.clim.2022.109018DOI: 10.1016/j.clim.2022.109018
Vollbach, K., Schuetz, C., Hedrich, C. M., Speth, F., Moenkemoeller, K., Brunner, J., . . . Haffner, D. (2022). Working Towards a Treat-to-Target Protocol in Juvenile Proliferative Lupus Nephritis - A Survey of Pediatric Rheumatologists and Nephrologists in Germany and Austria. FRONTIERS IN PEDIATRICS, 10. doi:10.3389/fped.2022.851998DOI: 10.3389/fped.2022.851998
Carlsson, E., Quist, A., Davies, J. C., Midgley, A., Smith, E. M. D., Bruce, I. N., . . . Hedrich, C. M. (2022). Longitudinal analysis of urinary proteins in lupus nephritis – A pilot study. Clinical Immunology, 236, 108948. doi:10.1016/j.clim.2022.108948DOI: 10.1016/j.clim.2022.108948
Systemic lupus erythematosus-are children small adults? (Journal article)
Alexander, T., & Hedrich, C. M. (2022). Systemic lupus erythematosus-are children small adults?. ZEITSCHRIFT FUR RHEUMATOLOGIE, 81(1), 28-35. doi:10.1007/s00393-021-01116-xDOI: 10.1007/s00393-021-01116-x
Antiphospholipid-Syndrom bei Kindern und Jugendlichen (Chapter)
Hedrich, C. M., & Kallinich, T. (2022). Antiphospholipid-Syndrom bei Kindern und Jugendlichen. In Pädiatrische Rheumatologie (pp. 533-549). Springer Berlin Heidelberg. doi:10.1007/978-3-662-60410-6_39DOI: 10.1007/978-3-662-60410-6_39
Biosimilars in der pädiatrischen Rheumatologie (Chapter)
Hedrich, C. M., & Cuevas, O. A. (2022). Biosimilars in der pädiatrischen Rheumatologie. In Pädiatrische Rheumatologie (pp. 259-264). Springer Berlin Heidelberg. doi:10.1007/978-3-662-60410-6_20DOI: 10.1007/978-3-662-60410-6_20
Classification of systemic lupus erythematosus in children and adults (Journal article)
Lythgoe, H., Lj, M., Hedrich, C. M., & Aringer, M. (2022). Classification of systemic lupus erythematosus in children and adults. CLINICAL IMMUNOLOGY, 234. doi:10.1016/j.clim.2021.108898DOI: 10.1016/j.clim.2021.108898
Nichtbakterielle Osteomyelitis bei Kindern und Jugendlichen (Chapter)
Hedrich, C. M., Morbach, H., & Girschick, H. (2022). Nichtbakterielle Osteomyelitis bei Kindern und Jugendlichen. In Pädiatrische Rheumatologie (pp. 865-874). Springer Berlin Heidelberg. doi:10.1007/978-3-662-60410-6_65DOI: 10.1007/978-3-662-60410-6_65
Systemic lupus erythematosus - Are children miniature adults? (Journal article)
Alexander, T., & Hedrich, C. M. (2022). Systemic lupus erythematosus - Are children miniature adults?. CLINICAL IMMUNOLOGY, 234. doi:10.1016/j.clim.2021.108907DOI: 10.1016/j.clim.2021.108907
2021
Comment on: Limited sensitivity and specificity of the ACR/EULAR-2019 classification criteria for SLE in JSLE?: Reply (Journal article)
Smith, E. M. D., Beresford, M. W., McCann, L., & Hedrich, C. M. (2022). Comment on: Limited sensitivity and specificity of the ACR/EULAR-2019 classification criteria for SLE in JSLE?: Reply. RHEUMATOLOGY, 61(1), E27-E28. doi:10.1093/rheumatology/keab667DOI: 10.1093/rheumatology/keab667
Brain, D., Plant-Hately, A., Heaton, B., Arshad, U., David, C., Hedrich, C., . . . Liptrott, N. J. (2021). Drug delivery systems as immunomodulators for therapy of infectious disease: Relevance to COVID-19. ADVANCED DRUG DELIVERY REVIEWS, 178. doi:10.1016/j.addr.2021.113848DOI: 10.1016/j.addr.2021.113848
EXPRESSION OF THE SARS-COV-2 RECEPTORS ACE2 AND TMPRSS2 IN THE RESPIRATORY TRACT OF CHILDREN AND ADULTS (Conference Paper)
Nuttall, A. G., Hedrich, C., Semple, C., Losty, P., Shukla, R., McPartland, J., . . . McNamara, P. (2021). EXPRESSION OF THE SARS-COV-2 RECEPTORS ACE2 AND TMPRSS2 IN THE RESPIRATORY TRACT OF CHILDREN AND ADULTS. In THORAX Vol. 76 (pp. A39). doi:10.1136/thorax-2021-BTSabstracts.63DOI: 10.1136/thorax-2021-BTSabstracts.63
Charras, A., Garau, J., Hofmann, S. R., Carlsson, E., Cereda, C., Russ, S., . . . Hedrich, C. M. (2021). DNA Methylation Patterns in CD8<SUP>+</SUP> T Cells Discern Psoriasis From Psoriatic Arthritis and Correlate With Cutaneous Disease Activity. FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 9. doi:10.3389/fcell.2021.746145DOI: 10.3389/fcell.2021.746145
Keenan, P., Brunner, J., Quan, A. S., Smitka, M., Hahn, G., Pain, C. E., . . . Hedrich, C. M. (2021). Diagnosis and Treatment of Small Vessel Childhood Primary Angiitis of the Central Nervous System (sv-cPACNS): An International Survey. FRONTIERS IN PEDIATRICS, 9. doi:10.3389/fped.2021.756612DOI: 10.3389/fped.2021.756612
1675 Real world treatment of juvenile systemic lupus erythematosus (JSLE): evidence from the UK JSLE cohort study (Conference Paper)
Egbivwie, N., Jorgensen, A. L., Beresford, M. W., Hedrich, C. M., & Smith, E. M. D. (2021). 1675 Real world treatment of juvenile systemic lupus erythematosus (JSLE): evidence from the UK JSLE cohort study. In Abstracts. BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health. doi:10.1136/archdischild-2021-rcpch.790DOI: 10.1136/archdischild-2021-rcpch.790
Giani, T., Smith, E. M., Al-Abadi, E., Armon, K., Bailey, K., Ciurtin, C., . . . Hedrich, C. M. (2021). Neuropsychiatric involvement in juvenile-onset systemic lupus erythematosus: Data from the UK Juvenile-onset systemic lupus erythematosus cohort study. LUPUS, 30(12), 1955-1965. doi:10.1177/09612033211045050DOI: 10.1177/09612033211045050
cardiac pathology and outcomes vary between Kawasaki disease and PIMS-TS (vol 229, 108780, 2021) (Journal article)
Felsenstein, S., Duong, P., Lane, S., Jones, C., Paine, C. E., & Hedrich, C. M. (2021). cardiac pathology and outcomes vary between Kawasaki disease and PIMS-TS (vol 229, 108780, 2021). CLINICAL IMMUNOLOGY, 231. doi:10.1016/j.clim.2021.108855DOI: 10.1016/j.clim.2021.108855
Editorial: Focusing on T-Cells for Novel Treatments of Systemic Lupus Erythematosus (Journal article)
Ichinose, K., Hedrich, C. M., Moulton, V. R., & Mizui, M. (2021). Editorial: Focusing on T-Cells for Novel Treatments of Systemic Lupus Erythematosus. FRONTIERS IN IMMUNOLOGY, 12. doi:10.3389/fimmu.2021.744866DOI: 10.3389/fimmu.2021.744866
Cardiac pathology and outcomes vary between Kawasaki disease and PIMS-TS (Journal article)
Felsenstein, S., Phuoc, D., Lane, S., Jones, C., Pain, C. E., & Hedrich, C. M. (2021). Cardiac pathology and outcomes vary between Kawasaki disease and PIMS-TS. CLINICAL IMMUNOLOGY, 229. doi:10.1016/j.clim.2021.108780DOI: 10.1016/j.clim.2021.108780
Establishing core domain sets for Chronic Nonbacterial Osteomyelitis (CNO) and Synovitis, Acne, Pustulosis, Hyperostosis, Osteitis (SAPHO): A report from the OMERACT 2020 special interest group (Journal article)
Oliver, M., Jayatilleke, A., Wu, E., Nuruzzaman, F., Aguiar, C., Lenert, A., . . . Zhao, Y. (2021). Establishing core domain sets for Chronic Nonbacterial Osteomyelitis (CNO) and Synovitis, Acne, Pustulosis, Hyperostosis, Osteitis (SAPHO): A report from the OMERACT 2020 special interest group. SEMINARS IN ARTHRITIS AND RHEUMATISM, 51(4), 957-961. doi:10.1016/j.semarthrit.2021.05.015DOI: 10.1016/j.semarthrit.2021.05.015
Carlsson, E., Midgley, A., Perkins, S., Caamano-Gutierrez, E., Gritzfeld, J. F., Beresford, M. W., & Hedrich, C. M. (2021). Serum protein signatures differentiate paediatric autoimmune/ inflammatory disorders. CLINICAL IMMUNOLOGY, 229. doi:10.1016/j.clim.2021.108790DOI: 10.1016/j.clim.2021.108790
Carlsson, E., Beresford, M. W., Ramanan, A. V., Dick, A. D., & Hedrich, C. M. (2021). Juvenile Idiopathic Arthritis Associated Uveitis. CHILDREN-BASEL, 8(8). doi:10.3390/children8080646DOI: 10.3390/children8080646
Hofmann, S. R., Carlsson, E., Kapplusch, F., Carvalho, A. L., Liloglou, T., Schulze, F., . . . Hedrich, C. M. (2021). Cyclic AMP Response Element Modulator-α Suppresses PD-1 Expression and Promotes Effector CD4<SUP>+</SUP> T Cells in Psoriasis. JOURNAL OF IMMUNOLOGY, 207(1), 55-64. doi:10.4049/jimmunol.2100240DOI: 10.4049/jimmunol.2100240
Janda, A., Schuetz, C., Canna, S., Gorelik, M., Heeg, M., Minden, K., . . . Speth, F. (2021). Therapeutic approaches to pediatric COVID-19: an online survey of pediatric rheumatologists. RHEUMATOLOGY INTERNATIONAL, 41(5), 911-920. doi:10.1007/s00296-021-04824-4DOI: 10.1007/s00296-021-04824-4
Massias, J. S., Smith, E. M. D., Al-Abadi, E., Armon, K., Bailey, K., Ciurtin, C., . . . Hedrich, C. M. (2021). Clinical and laboratory phenotypes in juvenile-onset Systemic Lupus Erythematosus across ethnicities in the UK. LUPUS, 30(4), 597-607. doi:10.1177/0961203320984251DOI: 10.1177/0961203320984251
Carvalho, A. L., & Hedrich, C. M. (2021). The Molecular Pathophysiology of Psoriatic Arthritis-The Complex Interplay Between Genetic Predisposition, Epigenetics Factors, and the Microbiome. FRONTIERS IN MOLECULAR BIOSCIENCES, 8. doi:10.3389/fmolb.2021.662047DOI: 10.3389/fmolb.2021.662047
Quan, A. S., Brunner, J., Rose, B., Smitka, M., Hahn, G., Pain, C. E., . . . Hedrich, C. M. (n.d.). Diagnosis and Treatment of Angiography Positive Medium to Large Vessel Childhood Primary Angiitis of Central Nervous System (p-cPACNS): An International Survey. Frontiers in Pediatrics, 9. doi:10.3389/fped.2021.654537DOI: 10.3389/fped.2021.654537
Smith, E. M. D., Rasul, S., Ciurtin, C., Al-Abadi, E., Armon, K., Bailey, K., . . . Hedrich, C. M. (2021). Limited sensitivity and specificity of the ACR/EULAR-2019 classification criteria for SLE in JSLE?-observations from the UK JSLE Cohort Study. RHEUMATOLOGY, 60(11), 5271-5281. doi:10.1093/rheumatology/keab210DOI: 10.1093/rheumatology/keab210
Hawcutt, D., McWilliam, S., Rodriguez-Martinez, C., Pacheco, R., Hedrich, C., Sinha, I., & Fernandes, R. (2021). The safety of hydroxychloroquine in paediatric populations: Analysis of worldwide pharmacovigilance reports. In BRITISH JOURNAL OF CLINICAL PHARMACOLOGY Vol. 87 (pp. 1622-1623). Retrieved from https://www.webofscience.com/
Charras, A., Smith, E., & Hedrich, C. M. (2021). Systemic Lupus Erythematosus in Children and Young People. CURRENT RHEUMATOLOGY REPORTS, 23(3). doi:10.1007/s11926-021-00985-0DOI: 10.1007/s11926-021-00985-0
Is chronic non-infectious osteomyelitis with mandibular involvement a distinct disease? (Other)
Murray, G. M., Schnabel, A., Alessi, M., Chopra, M., Mahmood, K., Killeen, O. G., . . . Ramanan, A. V. (2021). Is chronic non-infectious osteomyelitis with mandibular involvement a distinct disease?. In LANCET RHEUMATOLOGY (Vol. 3, Iss. 2, pp. E90-E92). doi:10.1016/S2665-9913(20)30414-8DOI: 10.1016/s2665-9913(20)30414-8
Is it time to re-think juvenile-onset Rheumatic and Musculoskeletal Diseases? - First steps towards individualised treatments to meet agreed targets. (Edited special journal issue)
Is it time to re-think juvenile-onset Rheumatic and Musculoskeletal Diseases? - First steps towards individualised treatments to meet agreed targets (2021). (Vol. 223).DOI: 10.1016/j.clim.2020.108647
Literaturübersicht zur Therapie der CNO mit TNF-α-Inhibitoren (Journal article)
Hospach, T., & Hedrich, C. (2021). Literaturübersicht zur Therapie der CNO mit TNF-α-Inhibitoren. Arthritis und Rheuma, 41(01), 56-57. doi:10.1055/a-1253-0075DOI: 10.1055/a-1253-0075
Antiphospholipid-Syndrom bei Kindern und Jugendlichen (Chapter)
Hedrich, C. M., & Kallinich, T. (2021). Antiphospholipid-Syndrom bei Kindern und Jugendlichen. In Pädiatrische Rheumatologie (pp. 1-18). Springer Berlin Heidelberg. doi:10.1007/978-3-662-60411-3_39-1DOI: 10.1007/978-3-662-60411-3_39-1
Biosimilars in der pädiatrischen Rheumatologie (Chapter)
Hedrich, C. M., & Cuevas, O. A. (2021). Biosimilars in der pädiatrischen Rheumatologie. In Pädiatrische Rheumatologie (pp. 1-6). Springer Berlin Heidelberg. doi:10.1007/978-3-662-60411-3_20-1DOI: 10.1007/978-3-662-60411-3_20-1
Chapter 32 Epigenetics (Chapter)
Hedrich, C. M. (2021). Chapter 32 Epigenetics. In Systemic Lupus Erythematosus (pp. 277-292). Elsevier. doi:10.1016/b978-0-12-814551-7.00032-5DOI: 10.1016/b978-0-12-814551-7.00032-5
Zhao, D. Y., McCann, L., Hahn, G., & Hedrich, C. M. (2021). Chronic nonbacterial osteomyelitis (CNO) and chronic recurrent multifocal osteomyelitis (CRMO). JOURNAL OF TRANSLATIONAL AUTOIMMUNITY, 4. doi:10.1016/j.jtauto.2021.100095DOI: 10.1016/j.jtauto.2021.100095
Nichtbakterielle Osteomyelitis bei Kindern und Jugendlichen (Chapter)
Hedrich, C. M., Morbach, H., & Girschick, H. (2021). Nichtbakterielle Osteomyelitis bei Kindern und Jugendlichen. In Pädiatrische Rheumatologie (pp. 1-10). Springer Berlin Heidelberg. doi:10.1007/978-3-662-60411-3_65-1DOI: 10.1007/978-3-662-60411-3_65-1
2020
Davies, J., Carlsson, E., Midgley, A., Smith, E., Bruce, I., Beresford, M., & Hedrich, C. (2020). A Panel of Urinary Proteins Predicts Active Lupus Nephritis and Response to Rituximab Treatment. ARTHRITIS & RHEUMATOLOGY, 72. Retrieved from http://gateway.webofknowledge.com/
Radiologist’s Perspectives on the Use of Imaging for Diagnosis and Monitoring of Chronic Nonbacterial Osteomyelitis (Preprint)
DOI: 10.21203/rs.3.rs-109523/v1
Sposito, F., McNamara, P. S., & Hedrich, C. M. (2020). Vasculitis in Cystic Fibrosis. FRONTIERS IN PEDIATRICS, 8. doi:10.3389/fped.2020.585275DOI: 10.3389/fped.2020.585275
Felsenstein, S., & Hedrich, C. M. (2020). SARS-CoV-2 infections in children and young people. CLINICAL IMMUNOLOGY, 220. doi:10.1016/j.clim.2020.108588DOI: 10.1016/j.clim.2020.108588
Dedieu, C., Albert, M. H., Mahlaoui, N., Hauck, F., Hedrich, C., Baumann, U., . . . Kühl, J. -S. (2020). Outcome of chronic granulomatous disease - conventional treatment versus stem cell transplantation.. Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology. doi:10.1111/pai.13402DOI: 10.1111/pai.13402
Felsenstein, S., Willis, E., Lythgoe, H., McCann, L., Cleary, A., Mahmood, K., . . . Hedrich, C. M. (2020). Presentation, Treatment Response and Short-Term Outcomes in Paediatric Multisystem Inflammatory Syndrome Temporally Associated with SARS-CoV-2 (PIMS-TS). JOURNAL OF CLINICAL MEDICINE, 9(10). doi:10.3390/jcm9103293DOI: 10.3390/jcm9103293
COVID-19 bei Kindern und Jugendlichen (Journal article)
Felsenstein, S., & Hedrich, C. M. (2020). COVID-19 bei Kindern und Jugendlichen. Arthritis und Rheuma, 40(05), 347-357. doi:10.1055/a-1255-8937DOI: 10.1055/a-1255-8937
Zhao, Y., Naden, R., Oliver, M., Wang, Z., Wu, E., Aguiar, C., . . . Ozen, S. (2020). Comparison of Clinicopathologic and Imaging Features Between Chronic Nonbacterial Osteomyelitis and Its Mimickers: A Multi-national 450 Case-Control Study. In ARTHRITIS & RHEUMATOLOGY Vol. 72. Retrieved from https://www.webofscience.com/
COVID-19 in children and young people (Journal article)
Felsenstein, S., & Hedrich, C. M. (2020). COVID-19 in children and young people. LANCET RHEUMATOLOGY, 2(9), E514-E516. doi:10.1016/S2665-9913(20)30212-5DOI: 10.1016/s2665-9913(20)30212-5
Janda, A., Schuetz, C., Heeg, M., Minden, K., Hedrich, C. M., Kallinich, T., . . . Speth, F. (2020). COVID-19: treatment strategies of German-speaking pediatric rheumatologists Results of an online survey. ZEITSCHRIFT FUR RHEUMATOLOGIE, 79(7), 710-717. doi:10.1007/s00393-020-00854-8DOI: 10.1007/s00393-020-00854-8
Hedrich, C. M., Morbach, H., Reiser, C., & Girschick, H. J. (2020). New Insights into Adult and Paediatric Chronic Non-bacterial Osteomyelitis CNO. CURRENT RHEUMATOLOGY REPORTS, 22(9). doi:10.1007/s11926-020-00928-1DOI: 10.1007/s11926-020-00928-1
Cuevas, O. A., & Hedrich, C. M. (2020). Biosimilars in pediatric rheumatology and their introduction into routine care. Clinical Immunology, 216. doi:10.1016/j.clim.2020.108447DOI: 10.1016/j.clim.2020.108447
Pain, C. E., Felsenstein, S., Cleary, G., Mayell, S., Conrad, K., Harave, S., . . . Hedrich, C. M. (2020). Novel paediatric presentation of COVID-19 with ARDS and cytokine storm syndrome without respiratory symptoms.. Lancet Rheumatology, 2(7), E376-E379. doi:10.1016/S2665-9913(20)30137-5DOI: 10.1016/S2665-9913(20)30137-5
Davies, J. C., Midgley, A., Carlsson, E., Donohue, S., Bruce, I. N., Beresford, M. W., & Hedrich, C. M. (2020). Urine and serum S100A8/A9 and S100A12 associate with active lupus nephritis and may predict response to rituximab treatment. RMD OPEN, 6(2). doi:10.1136/rmdopen-2020-001257DOI: 10.1136/rmdopen-2020-001257
Felsenstein, S., Herbert, J. A., McNamara, P. S., & Hedrich, C. M. (2020). COVID-19: Immunology and treatment options. CLINICAL IMMUNOLOGY, 215. doi:10.1016/j.clim.2020.108448DOI: 10.1016/j.clim.2020.108448
Davies, J., Midgley, A., Donohue, S., Bruce, I. N., Beresford, M., & Hedrich, C. (2020). URINE AND SERUM S100 PROTEINS ASSOCIATE WITH LUPUS NEPHRITIS AND RESPONSE TO TREATMENT. In ANNALS OF THE RHEUMATIC DISEASES Vol. 79 (pp. 348). doi:10.1136/annrheumdis-2020-eular.1180DOI: 10.1136/annrheumdis-2020-eular.1180
Hedrich, C. M. (2020). COVID-19-Considerations for the paediatric rheumatologist. CLINICAL IMMUNOLOGY, 214. doi:10.1016/j.clim.2020.108420DOI: 10.1016/j.clim.2020.108420
Massias, J., Smith, E., Beresford, M., & Hedrich, C. (2020). Clinical and Laboratory Characteristics in Juvenile-onset Systemic Lupus Erythematosus Across Age Groups. In ARTHRITIS & RHEUMATOLOGY Vol. 72 (pp. 95-96). Retrieved from https://www.webofscience.com/
Donohue, S., Midgley, A., Davies, J., Wright, R., Bruce, I., Beresford, M., & Hedrich, C. (2020). Differential Analysis of Serum and Urine S100 Proteins in Juvenile-onset Systemic Lupus Erythematosus (jSLE). In ARTHRITIS & RHEUMATOLOGY Vol. 72 (pp. 96-97). Retrieved from https://www.webofscience.com/
Donohue, S. J., Midgley, A., Davies, J. C., Wright, R. D., Bruce, I., Beresford, M. W., & Hedrich, C. M. (2020). Differential analysis of serum and urine S100 proteins in juvenile-onset systemic lupus erythematosus (jSLE). CLINICAL IMMUNOLOGY, 214. doi:10.1016/j.clim.2020.108375DOI: 10.1016/j.clim.2020.108375
Massias, J. S., Smith, E. M. D., Al-Abadi, E., Armon, K., Bailey, K., Ciurtin, C., . . . Hedrich, C. M. (2020). Clinical and laboratory characteristics in juvenile-onset systemic lupus erythematosus across age groups. LUPUS, 29(5), 474-481. doi:10.1177/0961203320909156DOI: 10.1177/0961203320909156
de Jesus, A. A., Hou, Y., Brooks, S., Malle, L., Biancotto, A., Huang, Y., . . . Goldbach-Mansky, R. (2020). Distinct interferon signatures and cytokine patterns define additional systemic autoinflammatory diseases. Journal of Clinical Investigation, 130(4), 1669-1682. doi:10.1172/jci129301DOI: 10.1172/jci129301
High-dose intravenous methylprednisolone in juvenile non-infectious uveitis: A retrospective analysis (Journal article)
Schnabel, A., Unger, E., Brueck, N., Berner, R., Range, U., Holl-Wieden, A., . . . Hedrich, C. M. (2020). High-dose intravenous methylprednisolone in juvenile non-infectious uveitis: A retrospective analysis. CLINICAL IMMUNOLOGY, 211. doi:10.1016/j.clim.2019.108327DOI: 10.1016/j.clim.2019.108327
Linking genetic variation with epigenetic profiles in Sjogren's syndrome (Journal article)
Arvaniti, P., Le Dantec, C., Charras, A., Arleevskaya, M. A., Hedrich, C. M., Zachou, K., . . . Renaudineau, Y. (2020). Linking genetic variation with epigenetic profiles in Sjogren's syndrome. CLINICAL IMMUNOLOGY, 210. doi:10.1016/j.clim.2019.108314DOI: 10.1016/j.clim.2019.108314
Qiao, W., Ding, H., Zuo, Y., Jiang, L., Zhou, J., Han, X., . . . Deng, G. -M. (2020). Lupus IgG deposition causes arthritis but inhibits bone destruction through competitive occupation of FcγRI and reduced RANKL signalling. CLINICAL & TRANSLATIONAL IMMUNOLOGY, 9(9). doi:10.1002/cti2.1174DOI: 10.1002/cti2.1174
Giani, T., Smith, E., Cimaz, R., Beresford, M., & Hedrich, C. (2020). Neuropsychiatric Involvement in Juvenile-onset Systemic Lupus Erythematosus (JSLE): Data from the UK JSLE Cohort Study. In ARTHRITIS & RHEUMATOLOGY Vol. 72. Retrieved from https://www.webofscience.com/
Nuruzzaman, F., Huang, M., Hedrich, C., Girschick, H., Cherian, J., Onel, K., . . . Zhao, Y. (2020). Perspectives of Radiologist Physicians in the Imaging of Chronic Nonbacterial Osteomyelitis. In ARTHRITIS & RHEUMATOLOGY Vol. 72 (pp. 105-107). Retrieved from https://www.webofscience.com/
Nuruzzaman, F., Huang, M., Hedrich, C., Girschick, H., Cherian, J., Sato, T. S., . . . Zhao, Y. (2020). Perspectives of Radiologist Physicians in the Imaging of Chronic Nonbacterial Osteomyelitis. In ARTHRITIS & RHEUMATOLOGY Vol. 72. Retrieved from https://www.webofscience.com/
de Jesus, A. A., Lin, B., Calvo, K. R., Sanchez, G. A. M., Mitchell, J. T., Marrero, B., . . . Goldbach-Mansky, R. (2020). Truncating Mutations in SAMD9L Cause an Early-Onset Immune-Dysregulatory Syndrome of Neutrophilic Panniculitis, Interstitial Lung Disease and Cytopenias. In JOURNAL OF CLINICAL IMMUNOLOGY Vol. 40 (pp. S149-S150). Retrieved from https://www.webofscience.com/
Vaskulitiden (Chapter)
Hedrich, C. M. (2020). Vaskulitiden. In Pädiatrie (pp. 1123-1130). Springer Berlin Heidelberg. doi:10.1007/978-3-662-60300-0_109DOI: 10.1007/978-3-662-60300-0_109
Hofmann, S., Kapplusch, F., Abraham, S., Northey, S., Russ, S., Schulze, F., . . . Hedrich, C. (2020). cAMP Response Element Modulator (CREM)α Promotes PD-1-effector CD4+T Cells in Psoriasis and Psoriatic Arthritis. In ARTHRITIS & RHEUMATOLOGY Vol. 72. Retrieved from https://www.webofscience.com/
2019
Tille, L., Schnabel, A., Laass, M. W., Hahn, G., Taut, H., Leszczynska, A., . . . Hedrich, C. M. (2020). Orbital inflammation and colitis in pediatric IgG4-related disease: A case report and review of the literature. EUROPEAN JOURNAL OF RHEUMATOLOGY, 7, S21-S27. doi:10.5152/eurjrheum.2019.19165DOI: 10.5152/eurjrheum.2019.19165
Smith, E. M. D., Lythgoe, H., Midgley, A., Beresford, M. W., & Hedrich, C. M. (2019). Juvenile-onset systemic lupus erythematosus: Update on clinical presentation, pathophysiology and treatment options. CLINICAL IMMUNOLOGY, 209. doi:10.1016/j.clim.2019.108274DOI: 10.1016/j.clim.2019.108274
cAMP Response Element Modulator α Induces Dual Specificity Protein Phosphatase 4 to Promote Effector T Cells in Juvenile-Onset Lupus (Journal article)
Hofmann, S. R., Mäbert, K., Kapplusch, F., Russ, S., Northey, S., Beresford, M. W., . . . Hedrich, C. M. (2019). cAMP Response Element Modulator α Induces Dual Specificity Protein Phosphatase 4 to Promote Effector T Cells in Juvenile-Onset Lupus. Journal of Immunology, 203(11), 2807-2816. doi:10.4049/jimmunol.1900760DOI: 10.4049/jimmunol.1900760
Kapplusch, F., Schulze, F., Rabe-Matschewsky, S., Russ, S., Herbig, M., Heymann, M. C., . . . Hofmann, S. R. (2019). CASP1 variants influence subcellular caspase-1 localization, pyroptosome formation, pro-inflammatory cell death and macrophage deformability. Clinical Immunology, 208. doi:10.1016/j.clim.2019.06.008DOI: 10.1016/j.clim.2019.06.008
Bone Pain in Upper Leg, Hip, Lower Back (Chapter)
Hedrich, C. M. (2019). Bone Pain in Upper Leg, Hip, Lower Back. In Pediatric Immunology (pp. 583-590). Springer International Publishing. doi:10.1007/978-3-030-21262-9_108DOI: 10.1007/978-3-030-21262-9_108
P40 S100A8/A9 and S100A12 may be biomarkers for juvenile-onset systemic lupus erythematosus (Journal article)
Donohue, S. J., Midgley, A., Bruce, I., Beresford, M. W., & Hedrich, C. M. (2019). P40 S100A8/A9 and S100A12 may be biomarkers for juvenile-onset systemic lupus erythematosus. Rheumatology, 58(Supplement_4). doi:10.1093/rheumatology/kez416.007DOI: 10.1093/rheumatology/kez416.007
SNPs talk to genes using landlines: long-range chromatin interactions link genetic risk with epigenetic patterns in Takayasu arteritis (Journal article)
Hedrich, C. M., & Tsokos, G. (2019). SNPs talk to genes using landlines: long-range chromatin interactions link genetic risk with epigenetic patterns in Takayasu arteritis. ANNALS OF THE RHEUMATIC DISEASES, 78(10), 1293-1295. doi:10.1136/annrheumdis-2019-215957DOI: 10.1136/annrheumdis-2019-215957
Kessel, C., Hedrich, C. M., & Foell, D. (2019). Innately adaptive or truly autoimmune.. Arthritis & rheumatology (Hoboken, N.J.). doi:10.1002/art.41107DOI: 10.1002/art.41107
The role of epigenetics in paediatric rheumatic disease (Journal article)
Charras, A., & Hedrich, C. M. (2019). The role of epigenetics in paediatric rheumatic disease. CURRENT OPINION IN RHEUMATOLOGY, 31(5), 450-463. doi:10.1097/BOR.0000000000000627DOI: 10.1097/BOR.0000000000000627
Young, S., Sharma, N., Lee, J. H., Chitu, V., Neumeister, V., Sohr, E., . . . Craig, A. W. B. (2019). Mast cells enhance sterile inflammation in chronic nonbacterial osteomyelitis. Disease Models and Mechanisms, 12(8). doi:10.1242/dmm.040097DOI: 10.1242/dmm.040097
Interference of canakinumab with commercial IL-1β ELISAs (Journal article)
Linge, M., Hedrich, C. M., Roesen-Wolff, A., & Winkler, S. (2019). Interference of canakinumab with commercial IL-1β ELISAs. CLINICAL IMMUNOLOGY, 205, 6-7. doi:10.1016/j.clim.2019.05.008DOI: 10.1016/j.clim.2019.05.008
CAMP RESPONSE ELEMENT MODULATOR (CREM) A INDUCES DUAL SPECIFICITY PROTEIN PHOSPHATASE (DUSP) 4 THROUGH EPIGENETIC REMODELING, PROMOTING IL-17A AND REDUCING IL-2 EXPRESSION IN T CELLS (Conference Paper)
Hofmann, S., Maebert, K., Kapplusch, F., Russ, S., & Hedrich, C. (2019). CAMP RESPONSE ELEMENT MODULATOR (CREM) A INDUCES DUAL SPECIFICITY PROTEIN PHOSPHATASE (DUSP) 4 THROUGH EPIGENETIC REMODELING, PROMOTING IL-17A AND REDUCING IL-2 EXPRESSION IN T CELLS. In ANNALS OF THE RHEUMATIC DISEASES Vol. 78 (pp. 172). doi:10.1136/annrheumdis-2019-eular.999DOI: 10.1136/annrheumdis-2019-eular.999
CLINICAL RESPONSE TO HIGH-DOSE INTRAVENOUS METHYLPREDNISOLONE IN CHILDHOOD AUTOIMMUNE UVEITIS: A RETROSPECTIVE ANALYSIS (Conference Paper)
Schnabel, A., Unger, E., Bruck, N., Holl-Wieden, A., Morbach, H., Berner, R., . . . Hedrich, C. (2019). CLINICAL RESPONSE TO HIGH-DOSE INTRAVENOUS METHYLPREDNISOLONE IN CHILDHOOD AUTOIMMUNE UVEITIS: A RETROSPECTIVE ANALYSIS. In ANNALS OF THE RHEUMATIC DISEASES Vol. 78 (pp. 983). doi:10.1136/annrheumdis-2019-eular.2495DOI: 10.1136/annrheumdis-2019-eular.2495
Ramanan, A. V., Hampson, L. V., Lythgoe, H., Jones, A. P., Hardwick, B., Hind, H., . . . Beresford, M. W. (2019). Defining consensus opinion to develop randomised controlled trials in rare diseases using Bayesian design: An example of a proposed trial of adalimumab versus pamidronate for children with CNO/CRMO. PLOS ONE, 14(6). doi:10.1371/journal.pone.0215739DOI: 10.1371/journal.pone.0215739
PATHOPHYSIOLOGY AND THERAPEUTIC CONSEQUENCES AUTO-INFLAMMATORY BONE DISORDERS (Conference Paper)
Hedrich, C. (2019). PATHOPHYSIOLOGY AND THERAPEUTIC CONSEQUENCES AUTO-INFLAMMATORY BONE DISORDERS. In ANNALS OF THE RHEUMATIC DISEASES Vol. 78 (pp. 57-58). doi:10.1136/annrheumdis-2019-eular.8494DOI: 10.1136/annrheumdis-2019-eular.8494
Smith, E. M., Lythgoe, H., & Hedrich, C. M. (2019). Vasculitis in juvenile-onset systemic lupus erythematosus. Frontiers in Pediatrics, 7(APR). doi:10.3389/fped.2019.00149DOI: 10.3389/fped.2019.00149
I017 The molecular pathophysiology of CNO and consequences for patient care (Journal article)
Hedrich, C. M. (2019). I017 The molecular pathophysiology of CNO and consequences for patient care. Rheumatology, 58(Supplement_3). doi:10.1093/rheumatology/kez109.016DOI: 10.1093/rheumatology/kez109.016
THE MOLECULAR PATHOPHYSIOLOGY OF CNO AND CONSEQUENCES FOR PATIENT CARE (Conference Paper)
Hedrich, C. M. (2019). THE MOLECULAR PATHOPHYSIOLOGY OF CNO AND CONSEQUENCES FOR PATIENT CARE. In RHEUMATOLOGY Vol. 58. Retrieved from https://www.webofscience.com/
Smith, E., Al-Abadi, E., Armon, K., Bailey, K., Ciurtin, C., Davidson, J., . . . Hedrich, C. M. (2019). Outcomes following mycophenolate mofetil versus cyclophosphamide induction treatment for proliferative juvenile-onset lupus nephritis.. Lupus, 961203319836712. doi:10.1177/0961203319836712DOI: 10.1177/0961203319836712
Conventional Treatment versus Stem Cell Transplantation Outcome in 105 Patients with Chronic Granulomatous Disease (Conference Paper)
Dedieu, C., Albert, M. H., Mahlaoui, N., Hauck, F., Hedrich, C., Baumann, U., . . . von Bernuth, H. (2019). Conventional Treatment versus Stem Cell Transplantation Outcome in 105 Patients with Chronic Granulomatous Disease. In JOURNAL OF CLINICAL IMMUNOLOGY Vol. 39 (pp. S136-S137). Retrieved from https://www.webofscience.com/
Chapter 21 Pharmacoepigenetics of Systemic Lupus Erythematosus (Chapter)
Hedrich, C. M. (2019). Chapter 21 Pharmacoepigenetics of Systemic Lupus Erythematosus. In Pharmacoepigenetics (pp. 597-608). Elsevier. doi:10.1016/b978-0-12-813939-4.00021-8DOI: 10.1016/b978-0-12-813939-4.00021-8
Schnabel, A., & Hedrich, C. M. (2019). Childhood Vasculitis. FRONTIERS IN PEDIATRICS, 6. doi:10.3389/fped.2018.00421DOI: 10.3389/fped.2018.00421
Chronic Non-Bacterial Osteomyelitis (Chapter)
Hedrich, C. M., & Girschick, H. J. (2019). Chronic Non-Bacterial Osteomyelitis. In Textbook of Autoinflammation (pp. 563-585). Springer International Publishing. doi:10.1007/978-3-319-98605-0_31DOI: 10.1007/978-3-319-98605-0_31
Chronic Nonbacterial Osteomyelitis (Chapter)
McCann, L., Beresford, M. W., Hahn, G., & Hedrich, C. M. (2019). Chronic Nonbacterial Osteomyelitis. In Auto-Inflammatory Syndromes (pp. 227-248). Springer International Publishing. doi:10.1007/978-3-319-96929-9_17DOI: 10.1007/978-3-319-96929-9_17
Pharmacoepigenetics of Systemic Lupus Erythematosus (Chapter)
Hedrich, C. M. (2019). Pharmacoepigenetics of Systemic Lupus Erythematosus. In PHARMACOEPIGENETICS (Vol. 10, pp. 597-608). doi:10.1016/B978-0-12-813939-4.00021-8DOI: 10.1016/B978-0-12-813939-4.00021-8
Primary CNS vasculitis in children (Journal article)
Hedrich, C. M., Hahn, G., & Smitka, M. (2019). Primary CNS vasculitis in children. AKTUELLE RHEUMATOLOGIE, 44(3), 205-211. doi:10.1055/a-0896-2526DOI: 10.1055/a-0896-2526
S100A8/A9 and S100A12 may be biomarkers for juvenile-onset systemic lupus erythematosus (Conference Paper)
Donohue, S. J., Midgley, A., Bruce, I., Beresford, M. W., & Hedrich, C. M. (2019). S100A8/A9 and S100A12 may be biomarkers for juvenile-onset systemic lupus erythematosus. In RHEUMATOLOGY Vol. 58. Retrieved from https://www.webofscience.com/
El-Helou, S. M., Biegner, A. -K., Bode, S., Ehl, S. R., Heeg, M., Maccari, M. E., . . . Grimbacher, B. (2019). The German National Registry of Primary Immunodeficiencies (2012-2017). FRONTIERS IN IMMUNOLOGY, 10. doi:10.3389/fimmu.2019.01272DOI: 10.3389/fimmu.2019.01272
Surace, A. E. A., & Hedrich, C. M. (2019). The Role of Epigenetics in Autoimmune/Inflammatory Disease. FRONTIERS IN IMMUNOLOGY, 10. doi:10.3389/fimmu.2019.01525DOI: 10.3389/fimmu.2019.01525
Vaskulitiden bei Kindern und Jugendlichen (Chapter)
Hedrich, C. M. (2019). Vaskulitiden bei Kindern und Jugendlichen. In Pädiatrie (pp. 1-8). Springer Berlin Heidelberg. doi:10.1007/978-3-642-54671-6_109-2DOI: 10.1007/978-3-642-54671-6_109-2
2018
Moghaddas, F., Zeng, P., Zhang, Y., Schuetzle, H., Brenner, S., Hofmann, S. R., . . . Masters, S. L. (2018). Autoinflammatory mutation in NLRC4 reveals a leucine-rich repeat (LRR)-LRR oligomerization interface. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 142(6), 1956-1967. doi:10.1016/j.jaci.2018.04.033DOI: 10.1016/j.jaci.2018.04.033
Brandt, D., Sohr, E., Pablik, J., Schnabel, A., Kapplusch, F., Maebert, K., . . . Hedrich, C. M. (2018). CD14(+) monocytes contribute to inflammation in chronic nonbacterial osteomyelitis (CNO) through increased NLRP3 inflammasome expression. CLINICAL IMMUNOLOGY, 196, 77-84. doi:10.1016/j.clim.2018.04.011DOI: 10.1016/j.clim.2018.04.011
Hedrich, C. M. (2018). Mechanistic aspects of epigenetic dysregulation in SLE. CLINICAL IMMUNOLOGY, 196, 3-11. doi:10.1016/j.clim.2018.02.002DOI: 10.1016/j.clim.2018.02.002
Zhao, Y., Wu, E. Y., Oliver, M. S., Cooper, A. M., Basiaga, M. L., Vora, S. S., . . . Ferguson, P. J. (2018). Consensus Treatment Plans for Chronic Nonbacterial Osteomyelitis Refractory to Nonsteroidal Antiinflammatory Drugs and/or With Active Spinal Lesions. ARTHRITIS CARE & RESEARCH, 70(8), 1228-1237. doi:10.1002/acr.23462DOI: 10.1002/acr.23462
Protokolle zur Klassifikation, Überwachung und Therapie in der Kinderrheumatologie (PRO-KIND): Chronisch nicht-bakterielle Osteomyelitis (CNO) (Journal article)
Oommen, P. T., Windschall, D., Weissbarth-Riedel, E., Trauzeddel, R., Grote, V., von Bismarck, P., . . . Schwarz, T. (2018). Protokolle zur Klassifikation, Überwachung und Therapie in der Kinderrheumatologie (PRO-KIND): Chronisch nicht-bakterielle Osteomyelitis (CNO). Arthritis und Rheuma, 38(04), 282-288. doi:10.1055/s-0038-1669796DOI: 10.1055/s-0038-1669796
Hedrich, C. M., Schnabel, A., & Hospach, T. (2018). Kawasaki Disease. FRONTIERS IN PEDIATRICS, 6. doi:10.3389/fped.2018.00198DOI: 10.3389/fped.2018.00198
An optimized whole blood assay measuring expression and activity of NLRP3, NLRC4 and AIM2 inflammasomes (Journal article)
Grinstein, L., Endter, K., Hedrich, C. M., Reinke, S., Luksch, H., Schulze, F., . . . Winkler, S. (2018). An optimized whole blood assay measuring expression and activity of NLRP3, NLRC4 and AIM2 inflammasomes. CLINICAL IMMUNOLOGY, 191, 100-109. doi:10.1016/j.clim.2017.11.011DOI: 10.1016/j.clim.2017.11.011
Hofmann, S. R., Laass, M. W., Fehrs, A., Schuppan, D., Zevallos, V. F., Salminger, D., . . . Hedrich, C. M. (2018). IL10 promoter haplotypes may contribute to altered cytokine expression and systemic inflammation in celiac disease. CLINICAL IMMUNOLOGY, 190, 15-21. doi:10.1016/j.clim.2018.02.010DOI: 10.1016/j.clim.2018.02.010
Brandt, D., & Hedrich, C. M. (2018). TCRαβ<SUP>+</SUP>CD3<SUP>+</SUP>CD4<SUP>-</SUP>CD8<SUP>-</SUP> (double negative) T cells in autoimmunity. AUTOIMMUNITY REVIEWS, 17(4), 422-430. doi:10.1016/j.autrev.2018.02.001DOI: 10.1016/j.autrev.2018.02.001
Cell-Specific Requirements for STAT Proteins and Type I IFN Receptor Signaling Discretely Regulate IL-24 and IL-10 Expression in NK Cells and Macrophages (Journal article)
Dabitao, D., Hedrich, C. M., Wang, F., Vacharathit, V., & Bream, J. H. (2018). Cell-Specific Requirements for STAT Proteins and Type I IFN Receptor Signaling Discretely Regulate IL-24 and IL-10 Expression in NK Cells and Macrophages. Journal of Immunology, 200(6), 2154-2164. doi:10.4049/jimmunol.1701340DOI: 10.4049/jimmunol.1701340
Bacterial arthritis in children and adolescents, core theme treatment. Results of the Worlitz consensus meeting 2016, part 2 (Journal article)
Hospach, T., Hedrich, C., Fernandez, F., Girschick, H., Borte, M., Guenther, A., . . . Huppertz, H. -I. (2018). Bacterial arthritis in children and adolescents, core theme treatment. Results of the Worlitz consensus meeting 2016, part 2. MONATSSCHRIFT KINDERHEILKUNDE, 166(3), 239-248. doi:10.1007/s00112-017-0327-8DOI: 10.1007/s00112-017-0327-8
Hedrich, C. M., Smith, E. M. D., & Beresford, M. W. (2018). Juvenile-onset systemic lupus erythematosus (jSLE) - Pathophysiological concepts and treatment options. Best Practice and Research: Clinical Rheumatology. doi:10.1016/j.berh.2018.02.001DOI: 10.1016/j.berh.2018.02.001
Mast Cells Enhance Sterile Inflammation in Chronic Nonbacterial Osteomyelitis (Journal article)
Young, S., Sharma, N., Lee, J. H. P., Chitu, V., Neumeister, V., Sohr, E., . . . Craig, A. W. B. (2018). Mast Cells Enhance Sterile Inflammation in Chronic Nonbacterial Osteomyelitis. doi:10.1101/259275DOI: 10.1101/259275
Bacterial arthritis in children and adolescents, core theme diagnostics. Results of the Worlitz consensus meeting 2016, part 1 (Journal article)
Hospach, T., Hedrich, C., Fernandez, F., Girschick, H., Borte, M., Guenther, A., . . . Huppertz, H. -I. (2018). Bacterial arthritis in children and adolescents, core theme diagnostics. Results of the Worlitz consensus meeting 2016, part 1. MONATSSCHRIFT KINDERHEILKUNDE, 166(2), 141-147. doi:10.1007/s00112-017-0326-9DOI: 10.1007/s00112-017-0326-9
Systemisch inflammatorische Erkrankungen als Differenzialdiagnose in der Neugeborenenperiode – Inflammasom-vermittelte Erkrankungen (Journal article)
Hofmann, S. R., Bruck, N., Hahn, G., Rösen-Wolff, A., & Hedrich, C. M. (2018). Systemisch inflammatorische Erkrankungen als Differenzialdiagnose in der Neugeborenenperiode – Inflammasom-vermittelte Erkrankungen. Arthritis und Rheuma, 38(02), 125-131. doi:10.1055/s-0038-1649292DOI: 10.1055/s-0038-1649292
Hinze, C. H., Holzinger, D., Lainka, E., Haas, J. -P., Speth, F., Kallinich, T., . . . Foell, D. (2018). Practice and consensus-based strategies in diagnosing and managing systemic juvenile idiopathic arthritis in Germany. PEDIATRIC RHEUMATOLOGY, 16. doi:10.1186/s12969-018-0224-2DOI: 10.1186/s12969-018-0224-2
APPROACHES TO AUTOIMMUNE DISEASES USING EPIGENETIC THERAPY (Chapter)
Hedrich, C. M. (2018). APPROACHES TO AUTOIMMUNE DISEASES USING EPIGENETIC THERAPY. In EPIGENETICS IN HUMAN DISEASE, 2ND EDITION (Vol. 6, pp. 387-405). doi:10.1016/B978-0-12-812215-0.00013-3DOI: 10.1016/B978-0-12-812215-0.00013-3
Chapter 13 Approaches to Autoimmune Diseases Using Epigenetic Therapy (Chapter)
Hedrich, C. M. (2018). Chapter 13 Approaches to Autoimmune Diseases Using Epigenetic Therapy. In Epigenetics in Human Disease (pp. 387-405). Elsevier. doi:10.1016/b978-0-12-812215-0.00013-3DOI: 10.1016/b978-0-12-812215-0.00013-3
DGPI Handbuch (Book)
Berner, R., Bialek, R., Forster, J., Härtel, C., Heininger, U., Huppertz, H. -I., . . . Simon, A. (Eds.) (2018). DGPI Handbuch. Georg Thieme Verlag. doi:10.1055/b-006-160379DOI: 10.1055/b-006-160379
Truncating Mutations in SAMD9L Cause an Early-Onset Immune-Dysregulatory Syndrome of Neutrophilic Panniculitis, Interstitial Lung Disease and Cytopenias (Conference Paper)
de Jesus, A. A., Marrero, B., Sanchez, G. A. M., Burnham, J. S., Chan, A., Stepanovskiy, Y., . . . Goldbach-Mansky, R. (2018). Truncating Mutations in SAMD9L Cause an Early-Onset Immune-Dysregulatory Syndrome of Neutrophilic Panniculitis, Interstitial Lung Disease and Cytopenias. In ARTHRITIS & RHEUMATOLOGY Vol. 70. Retrieved from https://www.webofscience.com/
2017
Hofmann, S. R., Kapplusch, F., Girschick, H. J., Morbach, H., Pablik, J., Ferguson, P. J., & Hedrich, C. M. (2017). Chronic Recurrent Multifocal Osteomyelitis (CRMO): Presentation, Pathogenesis, and Treatment. CURRENT OSTEOPOROSIS REPORTS, 15(6), 542-554. doi:10.1007/s11914-017-0405-9DOI: 10.1007/s11914-017-0405-9
Osteomyelitis bei Kindern und Jugendlichen (Journal article)
Schnabel, A., Peters, K., Hahn, G., & Hedrich, C. (2017). Osteomyelitis bei Kindern und Jugendlichen. Orthopädie & Rheuma, 20(6), 31-36. doi:10.1007/s15002-017-1016-7DOI: 10.1007/s15002-017-1016-7
Hofmann, S. R., Boettger, F., Range, U., Lueck, C., Morbach, H., Girschick, H. J., . . . Hedrich, C. M. (2017). Serum Interleukin-6 and CCL11/Eotaxin May Be Suitable Biomarkers for the Diagnosis of Chronic Nonbacterial Osteomyelitis. FRONTIERS IN PEDIATRICS, 5. doi:10.3389/fped.2017.00256DOI: 10.3389/fped.2017.00256
The German PID-net registry (Conference Paper)
El-Helou, S. M., Biegner, A. K., Bode, S., Ehl, S., Heeg, M., Ritterbusch, H., . . . Grimbacher, B. (2017). The German PID-net registry. In EUROPEAN JOURNAL OF IMMUNOLOGY Vol. 47 (pp. 174-175). Retrieved from https://www.webofscience.com/
Still's disease in children and adults (Journal article)
Hedrich, C. M., Guenther, C., & Aringer, M. (2017). Still's disease in children and adults. ZEITSCHRIFT FUR RHEUMATOLOGIE, 76(7), 595-607. doi:10.1007/s00393-017-0358-5DOI: 10.1007/s00393-017-0358-5
Bandola, J., Richter, C., Ryser, M., Jamal, A., Ashton, M. P., von Bonin, M., . . . Thieme, S. (2017). Neurotophin Receptor p75NTR Regulates Immune Function of Plasmacytoid Dendritic Cells. Frontiers in Immunology, 8. doi:10.3389/fimmu.2017.00981DOI: 10.3389/fimmu.2017.00981
TCR+ CD3+ CD4− CD8− effector T cells in psoriasis (Journal article)
Brandt, D., Sergon, M., Abraham, S., Maebert, K., & Hedrich, C. M. (2017). TCR+ CD3+ CD4− CD8− effector T cells in psoriasis. CLINICAL IMMUNOLOGY, 181, 51-59. doi:10.1016/j.clim.2017.06.002DOI: 10.1016/j.clim.2017.06.002
Hofmann, S. R., Kapplusch, F., Mäbert, K., & Hedrich, C. M. (2017). The molecular pathophysiology of chronic non-bacterial osteomyelitis (CNO)-a systematic review.. Molecular and cellular pediatrics, 4(1), 7. doi:10.1186/s40348-017-0073-yDOI: 10.1186/s40348-017-0073-y
Treatment Response and Longterm Outcomes in Children with Chronic Nonbacterial Osteomyelitis (Journal article)
Schnabel, A., Range, U., Hahn, G., Berner, R., & Hedrich, C. M. (2017). Treatment Response and Longterm Outcomes in Children with Chronic Nonbacterial Osteomyelitis. JOURNAL OF RHEUMATOLOGY, 44(7), 1058-1065. doi:10.3899/jrheum.161255DOI: 10.3899/jrheum.161255
Still's disease in children and adults (Journal article)
Hedrich, C. M., Guenther, C., & Aringer, M. (2017). Still's disease in children and adults. HAUTARZT, 68(6), 497-511. doi:10.1007/s00105-017-3983-7DOI: 10.1007/s00105-017-3983-7
van den Bruck, R., Weil, P. P., Ziegenhals, T., Schreiner, P., Juranek, S., Gödde, D., . . . Debatin, K. -M. (2017). Abstracts of the 52nd Workshop for Pediatric Research : Frankfurt, Germany. 27-28 October 2016.. Molecular and cellular pediatrics, 4(Suppl 1), 5. doi:10.1186/s40348-017-0071-0DOI: 10.1186/s40348-017-0071-0
Walsh, S., Knöfler, R., Hahn, G., Lohse, J., Berner, R., Brenner, S., . . . Hedrich, C. M. (2017). Childhood primary large vessel CNS vasculitis: single-centre experience and review of the literature. Clinical and Experimental Rheumatology.
DNA methylation in systemic lupus erythematosus (Journal article)
Hedrich, C. M., Maebert, K., Rauen, T., & Tsokos, G. C. (2017). DNA methylation in systemic lupus erythematosus. EPIGENOMICS, 9(4), 505-525. doi:10.2217/epi-2016-0096DOI: 10.2217/epi-2016-0096
Childhood primary large vessel CNS vasculitis: single-centre experience and review of the literature. (Journal article)
Walsh, S., Knöfler, R., Hahn, G., Lohse, J., Berner, R., Brenner, S., . . . Hedrich, C. M. (2017). Childhood primary large vessel CNS vasculitis: single-centre experience and review of the literature.. Clinical and experimental rheumatology, 35 Suppl 103(1), 213-220.
Childhood primary large-vessel CNS vasculitis: single-centre experience and review of the literature (Journal article)
Walsh, S., Knoefler, R., Hahn, G., Lohse, J., Berner, R., Brenner, S., . . . Hedrich, C. M. (2017). Childhood primary large-vessel CNS vasculitis: single-centre experience and review of the literature. CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, 35(1), S213-S220. Retrieved from https://www.webofscience.com/
Hinze, C. H., Holzinger, D., Lainka, E., Haas, J. -P., Speth, F., Kallinich, T., . . . Föll, D. (2017). Harmonisierung der Diagnostik und Therapie der systemischen juvenilen idiopathischen Arthritis in Deutschland. Arthritis und Rheuma, 37(04), 250-259. doi:10.1055/s-0037-1618435DOI: 10.1055/s-0037-1618435
SLE-Associated Defects Promote Altered T Cell Function (Journal article)
Crispin, J. C., Hedrich, C. M., Suarez-Fueyo, A., Comte, D., & Tsokos, G. C. (2017). SLE-Associated Defects Promote Altered T Cell Function. CRITICAL REVIEWS IN IMMUNOLOGY, 37(1), 39-58. doi:10.1615/CritRevImmunol.2018025213DOI: 10.1615/CritRevImmunol.2018025213
2016
Unexpectedly high incidences of chronic non-bacterial as compared to bacterial osteomyelitis in children (Journal article)
Schnabel, A., Range, U., Hahn, G., Siepmann, T., Berner, R., & Hedrich, C. M. (2016). Unexpectedly high incidences of chronic non-bacterial as compared to bacterial osteomyelitis in children. RHEUMATOLOGY INTERNATIONAL, 36(12), 1737-1745. doi:10.1007/s00296-016-3572-6DOI: 10.1007/s00296-016-3572-6
Chronic Nonbacterial Osteomyelitis: Pathophysiological Concepts and Current Treatment Strategies (Journal article)
Hofmann, S. R., Schnabel, A., Roesen-Wolff, A., Morbach, H., Girschick, H. J., & Hedrich, C. M. (2016). Chronic Nonbacterial Osteomyelitis: Pathophysiological Concepts and Current Treatment Strategies. JOURNAL OF RHEUMATOLOGY, 43(11), 1956-1964. doi:10.3899/jrheum.160256DOI: 10.3899/jrheum.160256
Enzymatically Inactive Procaspase 1 stabilizes the ASC Pyroptosome and Supports Pyroptosome Spreading during Cell Division (Journal article)
Stein, R., Kapplusch, F., Heymann, M. C., Russ, S., Staroske, W., Hedrich, C. M., . . . Hofmann, S. R. (2016). Enzymatically Inactive Procaspase 1 stabilizes the ASC Pyroptosome and Supports Pyroptosome Spreading during Cell Division. JOURNAL OF BIOLOGICAL CHEMISTRY, 291(35), 18419-18429. doi:10.1074/jbc.M116.718668DOI: 10.1074/jbc.M116.718668
Inflammasome and Gout (Journal article)
Aringer, M., Hedrich, C., & Tausche, A. -K. (2016). Inflammasome and Gout. ZEITSCHRIFT FUR RHEUMATOLOGIE, 75(6), 537-541. doi:10.1007/s00393-016-0131-1DOI: 10.1007/s00393-016-0131-1
Proceedings of the 2016 Childhood Arthritis and Rheumatology Research Alliance (CARRA) Scientific Meeting : Toronto, Canada. 14-17 April 2016. (2016). Pediatric rheumatology online journal, 14 Suppl 1, 41. doi:10.1186/s12969-016-0098-0DOI: 10.1186/s12969-016-0098-0
Chronic nonbacterial and bacterial osteomyelitis. Differential diagnostics (Journal article)
Schnabel, A., Berner, R., & Hedrich, C. M. (2016). Chronic nonbacterial and bacterial osteomyelitis. Differential diagnostics. MONATSSCHRIFT KINDERHEILKUNDE, 164(6), 505-517. doi:10.1007/s00112-016-0094-yDOI: 10.1007/s00112-016-0094-y
Serum biomarkers for the diagnosis and monitoring of chronic recurrent multifocal osteomyelitis (CRMO) (Journal article)
Hofmann, S. R., Kubasch, A. S., Range, U., Laass, M. W., Morbach, H., Girschick, H. J., & Hedrich, C. M. (2016). Serum biomarkers for the diagnosis and monitoring of chronic recurrent multifocal osteomyelitis (CRMO). RHEUMATOLOGY INTERNATIONAL, 36(6), 769-779. doi:10.1007/s00296-016-3466-7DOI: 10.1007/s00296-016-3466-7
Caspase-1 regulates autoinflammation in rheumatic diseases (Journal article)
Winkler, S., Hedrich, C. M., & Roesen-Wolff, A. (2016). Caspase-1 regulates autoinflammation in rheumatic diseases. ZEITSCHRIFT FUR RHEUMATOLOGIE, 75(3), 265-+. doi:10.1007/s00393-016-0077-3DOI: 10.1007/s00393-016-0077-3
Shaping the spectrum - From autoinflammation to autoimmunity (Journal article)
Hedrich, C. M. (2016). Shaping the spectrum - From autoinflammation to autoimmunity. CLINICAL IMMUNOLOGY, 165, 21-28. doi:10.1016/j.clim.2016.03.002DOI: 10.1016/j.clim.2016.03.002
Acrodermatitis Chronica Atrophicans (Journal article)
Bruck, N., Fiebig, B., Schnabel, A., Lander, F., Berner, R., & Hedrich, C. M. (2016). Acrodermatitis Chronica Atrophicans. JOURNAL OF PEDIATRICS, 170, 335-+. doi:10.1016/j.jpeds.2015.11.011DOI: 10.1016/j.jpeds.2015.11.011
Chapter 30 Epigenetics (Chapter)
Hedrich, C. M. (2016). Chapter 30 Epigenetics. In Systemic Lupus Erythematosus (pp. 255-264). Elsevier. doi:10.1016/b978-0-12-801917-7.00030-9DOI: 10.1016/b978-0-12-801917-7.00030-9
Pediatric stroke (Journal article)
Von Der Hagen, M., Bodechtel, U., Pütz, V., Hahn, G., Hedrich, C. M., Brenner, S., . . . Knöfler, R. (2016). Pediatric stroke. Padiatrische Praxis, 86(1), 55-68.
2015
Altered expression of IL-10 family cytokines in monocytes from CRMO patients result in enhanced IL-1β expression and release (Journal article)
Hofmann, S. R., Kubasch, A. S., Ioannidis, C., Roesen-Wolff, A., Girschick, H. J., Morbach, H., & Hedrich, C. M. (2015). Altered expression of IL-10 family cytokines in monocytes from CRMO patients result in enhanced IL-1β expression and release. CLINICAL IMMUNOLOGY, 161(2), 300-307. doi:10.1016/j.clim.2015.09.013DOI: 10.1016/j.clim.2015.09.013
Fluorescent tags influence the enzymatic activity and subcellular localization of procaspase-1 (Journal article)
Heymann, M. C., Rabe, S., Russ, S., Kapplusch, F., Schulze, F., Stein, R., . . . Hofmann, S. R. (2015). Fluorescent tags influence the enzymatic activity and subcellular localization of procaspase-1. CLINICAL IMMUNOLOGY, 160(2), 172-179. doi:10.1016/j.clim.2015.05.011DOI: 10.1016/j.clim.2015.05.011
Altered expression of IL-10 family cytokines in CRMO result in enhanced inflammasome activation (Journal article)
Hofmann, S., Kubasch, A., Rösen-Wolff, A., Girschick, H., Morbach, H., & Hedrich, C. (2015). Altered expression of IL-10 family cytokines in CRMO result in enhanced inflammasome activation. Pediatric rheumatology online journal, 13(Suppl 1), O28. doi:10.1186/1546-0096-13-s1-o28DOI: 10.1186/1546-0096-13-s1-o28
Choosing the right treatment for patients with a severe course of chronic non-bacterial osteomyelitis (CNO) - pamidronate or TNF-α blockade? (Journal article)
Morbach, H., Schnabel, A., Bruck, N., Holl-Wieden, A., Girschick, H., & Hedrich, C. (2015). Choosing the right treatment for patients with a severe course of chronic non-bacterial osteomyelitis (CNO) - pamidronate or TNF-α blockade?. Pediatric rheumatology online journal, 13(Suppl 1), P190. doi:10.1186/1546-0096-13-s1-p190DOI: 10.1186/1546-0096-13-s1-p190
Serum biomarkers for the diagnosis of chronic recurrent multifocal osteomyelitis (CRMO) (Journal article)
Hofmann, S., Kubasch, A. -S., Range, U., Laass, M., Rösen-Wolff, A., Schwarz, T., . . . Hedrich, C. (2015). Serum biomarkers for the diagnosis of chronic recurrent multifocal osteomyelitis (CRMO). Pediatric rheumatology online journal, 13(Suppl 1), O77. doi:10.1186/1546-0096-13-s1-o77DOI: 10.1186/1546-0096-13-s1-o77
Current understanding of the pathophysiology of systemic juvenile idiopathic arthritis (sJIA) and target-directed therapeutic approaches (Journal article)
Bruck, N., Schnabel, A., & Hedrich, C. M. (2015). Current understanding of the pathophysiology of systemic juvenile idiopathic arthritis (sJIA) and target-directed therapeutic approaches. CLINICAL IMMUNOLOGY, 159(1), 72-83. doi:10.1016/j.clim.2015.04.018DOI: 10.1016/j.clim.2015.04.018
Epigenetics and the Regulation of Inflammation (Chapter)
Hedrich, C. M. (2015). Epigenetics and the Regulation of Inflammation. In Epigenetics and Dermatology (pp. 85-111). Elsevier. doi:10.1016/b978-0-12-800957-4.00006-0DOI: 10.1016/b978-0-12-800957-4.00006-0
Altered Expression of IL-10 Family Cytokines in Chronic Recurrent Multifocal Osteomyelitis Result in Enhanced Inflammasome Activation (Conference Paper)
Hofmann, S., Roesen-Wolff, A., Girschick, H., Morbach, H., & Hedrich, C. (2015). Altered Expression of IL-10 Family Cytokines in Chronic Recurrent Multifocal Osteomyelitis Result in Enhanced Inflammasome Activation. In ARTHRITIS & RHEUMATOLOGY Vol. 67. Retrieved from https://www.webofscience.com/
Chapter 6 Epigenetics and the Regulation of Inflammation (Chapter)
Hedrich, C. M. (2015). Chapter 6 Epigenetics and the Regulation of Inflammation. In Epigenetics and Dermatology (pp. 85-111). Elsevier. doi:10.1016/b978-0-12-800957-4.00006-0DOI: 10.1016/b978-0-12-800957-4.00006-0
2014
Scleroderma in childhood and adolescence - Diagnosis and therapy (Journal article)
Girschick, H. J., Hedrich, C., Trcka, J., & Schäd-Trcka, S. (2014). Scleroderma in childhood and adolescence - Diagnosis and therapy. Padiatrische Praxis, 83(2), 289-299.
Scleroderma in childhood and adolescence-diagnosis and therapy. 1. Localized scleroderma (Journal article)
Girschick, H. J., Hedrich, C., Trcka, J., & Schäd-Trcka, S. (2014). Scleroderma in childhood and adolescence-diagnosis and therapy. 1. Localized scleroderma. Padiatrische Praxis, 83(1), 87-93.
Stat3 promotes IL-10 expression in lupus T cells through trans-activation and chromatin remodeling (Journal article)
Hedrich, C. M., Rauen, T., Apostolidis, S. A., Grammatikos, A. P., Rodriguez, N. R., Ioannidis, C., . . . Tsokos, G. C. (2014). Stat3 promotes IL-10 expression in lupus T cells through trans-activation and chromatin remodeling. Proceedings of the National Academy of Sciences of the United States of America, 111(37), 13457-13462. doi:10.1073/pnas.1408023111DOI: 10.1073/pnas.1408023111
CaMK4-dependent activation of AKT/mTOR and CREM-alpha underlies autoimmunity-associated Th17 imbalance (Journal article)
Koga, T., Hedrich, C. M., Mizui, M., Yoshida, N., Otomo, K., Lieberman, L. A., . . . Tsokos, G. C. (2014). CaMK4-dependent activation of AKT/mTOR and CREM-alpha underlies autoimmunity-associated Th17 imbalance. Journal of Clinical Investigation, 124(5), 2234-2245. doi:10.1172/JCI73411DOI: 10.1172/JCI73411
cAMP Responsive Element Modulator (CREM) α Mediates Chromatin Remodeling of CD8 during the Generation of CD3+CD4−CD8− T Cells (Journal article)
Hedrich, C. M., Crispin, J. C., Rauen, T., Ioannidis, C., Koga, T., Rodriguez, N. R., . . . Tsokos, G. C. (2014). cAMP Responsive Element Modulator (CREM) α Mediates Chromatin Remodeling of CD8 during the Generation of CD3+CD4−CD8− T Cells. Journal of Biological Chemistry, 289(4), 2361-2370. doi:10.1074/jbc.M113.523605DOI: 10.1074/jbc.M113.523605
Epigenetic regulation of cytokine expression in systemic lupus erythematosus with special focus on T cells (Journal article)
Hedrich, C. M., Crispin, J. C., & Tsokos, G. C. (2014). Epigenetic regulation of cytokine expression in systemic lupus erythematosus with special focus on T cells. AUTOIMMUNITY, 47(4), 234-241. doi:10.3109/08916934.2013.801462DOI: 10.3109/08916934.2013.801462
Epigenetics in Autoimmunity (Chapter)
Hedrich, C. M. (2014). Epigenetics in Autoimmunity. In Encyclopedia of Medical Immunology (pp. 399-408). Springer New York. doi:10.1007/978-0-387-84828-0_411DOI: 10.1007/978-0-387-84828-0_411
Juvenile Diseases: SLE in Children (Chapter)
Hedrich, C. M. (2014). Juvenile Diseases: SLE in Children. In Encyclopedia of Medical Immunology (pp. 596-603). Springer New York. doi:10.1007/978-0-387-84828-0_395DOI: 10.1007/978-0-387-84828-0_395
Stat3 Promotes IL-10 Expression in SLE T Cells through Transactivation and Chromatin Remodeling (Conference Paper)
Hedrich, C., Rauen, T., Apostolidis, S., Grammatikos, A. P., Rodriguez, N. R., Ioannidis, C., . . . Tsokos, G. C. (2014). Stat3 Promotes IL-10 Expression in SLE T Cells through Transactivation and Chromatin Remodeling. In ARTHRITIS & RHEUMATOLOGY Vol. 66 (pp. S456-S457). Retrieved from https://www.webofscience.com/
Stat3 and Stat5 govern IL-10 expression in T cells through trans-activation and epigenetic remodelling in health and disease (Journal article)
Hedrich, C. M., Rauen, T., Crispin, J. C., & Tsokos, G. C. (2014). Stat3 and Stat5 govern IL-10 expression in T cells through trans-activation and epigenetic remodelling in health and disease. Molecular and Cellular Pediatrics, 1(Suppl 1), A17. doi:10.1186/2194-7791-1-s1-a17DOI: 10.1186/2194-7791-1-s1-a17
2013
Autoinflammatory bone disorders with special focus on chronic recurrent multifocal osteomyelitis (CRMO) (Journal article)
Hedrich, C. M., Hofmann, S. R., Pablik, J., Morbach, H., & Girschick, H. J. (2013). Autoinflammatory bone disorders with special focus on chronic recurrent multifocal osteomyelitis (CRMO). PEDIATRIC RHEUMATOLOGY, 11. doi:10.1186/1546-0096-11-47DOI: 10.1186/1546-0096-11-47
cAMP-responsive Element Modulator α (CREMα) <i>trans</i>-Represses the Transmembrane Glycoprotein CD8 and Contributes to the Generation of CD3<SUP>+</SUP>CD4<SUP>-</SUP>CD8<SUP>-</SUP> T Cells in Health and Disease (Journal article)
Hedrich, C. M., Rauen, T., Crispin, J. C., Koga, T., Ioannidis, C., Zajdel, M., . . . Tsokos, G. C. (2013). cAMP-responsive Element Modulator α (CREMα) <i>trans</i>-Represses the Transmembrane Glycoprotein CD8 and Contributes to the Generation of CD3<SUP>+</SUP>CD4<SUP>-</SUP>CD8<SUP>-</SUP> T Cells in Health and Disease. JOURNAL OF BIOLOGICAL CHEMISTRY, 288(44), 31880-31887. doi:10.1074/jbc.M113.508655DOI: 10.1074/jbc.M113.508655
Protein Phosphatase 2A Enables Expression of Interleukin 17 (IL-17) through Chromatin Remodeling (Journal article)
Apostolidis, S. A., Rauen, T., Hedrich, C. M., Tsokos, G. C., & Crispin, J. C. (2013). Protein Phosphatase 2A Enables Expression of Interleukin 17 (IL-17) through Chromatin Remodeling. JOURNAL OF BIOLOGICAL CHEMISTRY, 288(37), 26775-26784. doi:10.1074/jbc.M113.483743DOI: 10.1074/jbc.M113.483743
Gene-function studies in systemic lupus erythematosus (Journal article)
Crispin, J. C., Hedrich, C. M., & Tsokos, G. C. (2013). Gene-function studies in systemic lupus erythematosus. NATURE REVIEWS RHEUMATOLOGY, 9(8), 476-484. doi:10.1038/nrrheum.2013.78DOI: 10.1038/nrrheum.2013.78
The Catalytic Subunit of Protein Phosphatase 2A (PP2Ac) Promotes DNA Hypomethylation by Suppressing the Phosphorylated Mitogen-activated Protein Kinase/Extracellular Signal-regulated Kinase (ERK) Kinase (MEK)/Phosphorylated ERK/DNMT1 Protein Pathway in T-cells from Controls and Systemic Lupus Erythematosus Patients (Journal article)
Sunahori, K., Nagpal, K., Hedrich, C. M., Mizui, M., Fitzgerald, L. M., & Tsokos, G. C. (2013). The Catalytic Subunit of Protein Phosphatase 2A (PP2Ac) Promotes DNA Hypomethylation by Suppressing the Phosphorylated Mitogen-activated Protein Kinase/Extracellular Signal-regulated Kinase (ERK) Kinase (MEK)/Phosphorylated ERK/DNMT1 Protein Pathway in T-cells from Controls and Systemic Lupus Erythematosus Patients. JOURNAL OF BIOLOGICAL CHEMISTRY, 288(30). doi:10.1074/jbc.M113.467266DOI: 10.1074/jbc.M113.467266
CAMP RESPONSIVE ELEMENT MODULATOR (CREM) ALPHA CONTRIBUTES TO DECREASED NOTCH-1 EXPRESSION IN T CELLS FROM PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS (SLE) (Conference Paper)
Rauen, T., Grammatikos, A., Hedrich, C. M., Kyttaris, V. C., Tenbrock, K., Raffetseder, U., . . . Tsokos, G. C. (2013). CAMP RESPONSIVE ELEMENT MODULATOR (CREM) ALPHA CONTRIBUTES TO DECREASED NOTCH-1 EXPRESSION IN T CELLS FROM PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS (SLE). In ANNALS OF THE RHEUMATIC DISEASES Vol. 71 (pp. 155). doi:10.1136/annrheumdis-2012-eular.1969DOI: 10.1136/annrheumdis-2012-eular.1969
IMMUNOLOGICAL AND GENETIC BASIS OF CRMO (Conference Paper)
Hedrich, C. M. (2013). IMMUNOLOGICAL AND GENETIC BASIS OF CRMO. In ANNALS OF THE RHEUMATIC DISEASES Vol. 71 (pp. 10). doi:10.1136/annrheumdis-2012-eular.1514DOI: 10.1136/annrheumdis-2012-eular.1514
cAMP responsive element modulator: a critical regulator of cytokine production (Journal article)
Rauen, T., Hedrich, C. M., Tenbrock, K., & Tsokos, G. C. (2013). cAMP responsive element modulator: a critical regulator of cytokine production. TRENDS IN MOLECULAR MEDICINE, 19(4), 262-269. doi:10.1016/j.molmed.2013.02.001DOI: 10.1016/j.molmed.2013.02.001
Sengler, C., Girschick, H. J., & Hedrich, C. M. (2013). Pathogenese des systemischen Lupus erythematodes (SLE) im Kindesalter. Arthritis und Rheuma, 33(03), 173-178. doi:10.1055/s-0037-1618176DOI: 10.1055/s-0037-1618176
A clinical and pathomechanistic profile of chronic nonbacterial osteomyelitis/chronic recurrent multifocal osteomyelitis and challenges facing the field (Journal article)
Hedrich, C. M., Hahn, G., Girschick, H. J., & Morbach, H. (2013). A clinical and pathomechanistic profile of chronic nonbacterial osteomyelitis/chronic recurrent multifocal osteomyelitis and challenges facing the field. EXPERT REVIEW OF CLINICAL IMMUNOLOGY, 9(9), 845-854. doi:10.1586/1744666X.2013.824670DOI: 10.1586/1744666X.2013.824670
Autoinflammatory bone disorders (Journal article)
Morbach, H., Hedrich, C. M., Beer, M., & Girschick, H. J. (2013). Autoinflammatory bone disorders. CLINICAL IMMUNOLOGY, 147(3), 185-196. doi:10.1016/j.clim.2012.12.012DOI: 10.1016/j.clim.2012.12.012
Bridging the gap between autoinflammation and autoimmunity (Journal article)
Hedrich, C. M., & Tsokos, G. C. (2013). Bridging the gap between autoinflammation and autoimmunity. CLINICAL IMMUNOLOGY, 147(3), 151-154. doi:10.1016/j.clim.2013.03.006DOI: 10.1016/j.clim.2013.03.006
Inhibition of Calcium/Calmodulin-Dependent Protein Kinase 4 Ameliorates Th17 Related Autoimmune Disorder (Conference Paper)
Koga, T., Hedrich, C., Mizui, M., Yoshida, N., Lieberman, L., Crispin, J. C., & Tsokos, G. C. (2013). Inhibition of Calcium/Calmodulin-Dependent Protein Kinase 4 Ameliorates Th17 Related Autoimmune Disorder. In ARTHRITIS AND RHEUMATISM Vol. 65 (pp. S242). Retrieved from https://www.webofscience.com/
Pulmonary Hemosiderosis as possible Primary Manifestation of juvenile systemic Lupus erythematosus (Conference Paper)
Fiebig, B., Bruck, N., Schnabel, A., Hahn, G., Vogelberg, C., Berner, R., & Hedrich, C. (2013). Pulmonary Hemosiderosis as possible Primary Manifestation of juvenile systemic Lupus erythematosus. In ZEITSCHRIFT FUR RHEUMATOLOGIE Vol. 72 (pp. 70). Retrieved from https://www.webofscience.com/
cAMP Responsive Element Modulator (CREM) α Governs CD8 Expression and Contributes to the Generation of CD3<SUP>+</SUP> CD4<SUP>-</SUP>CD8<SUP>-</SUP> T Cells in Lupus (Conference Paper)
Hedrich, C. M., Crispin, J. C., Rauen, T., Ioannidis, C., Koga, T., Rodriguez, N. R., . . . Tsokos, G. C. (2013). cAMP Responsive Element Modulator (CREM) α Governs CD8 Expression and Contributes to the Generation of CD3<SUP>+</SUP> CD4<SUP>-</SUP>CD8<SUP>-</SUP> T Cells in Lupus. In ARTHRITIS AND RHEUMATISM Vol. 65 (pp. S1163). Retrieved from https://www.webofscience.com/
2012
cAMP-responsive Element Modulator α (CREMα) Contributes to Decreased Notch-1 Expression in T Cells from Patients with Active Systemic Lupus Erythematosus (SLE) (Journal article)
Rauen, T., Grammatikos, A. P., Hedrich, C. M., Floege, J., Tenbrock, K., Ohl, K., . . . Tsokos, G. C. (2012). cAMP-responsive Element Modulator α (CREMα) Contributes to Decreased Notch-1 Expression in T Cells from Patients with Active Systemic Lupus Erythematosus (SLE). JOURNAL OF BIOLOGICAL CHEMISTRY, 287(51), 42525-42532. doi:10.1074/jbc.M112.425371DOI: 10.1074/jbc.M112.425371
CD3-T Cell Receptor Co-stimulation through SLAMF3 and SLAMF6 Receptors Enhances RORγt Recruitment to the <i>IL17A</i> Promoter in Human T Lymphocytes (Journal article)
Chatterjee, M., Hedrich, C. M., Rauen, T., Ioannidis, C., Terhorst, C., & Tsokos, G. C. (2012). CD3-T Cell Receptor Co-stimulation through SLAMF3 and SLAMF6 Receptors Enhances RORγt Recruitment to the <i>IL17A</i> Promoter in Human T Lymphocytes. JOURNAL OF BIOLOGICAL CHEMISTRY, 287(45). doi:10.1074/jbc.M112.415067DOI: 10.1074/jbc.M112.415067
Anakinra: A safe and effective first-line treatment in systemic onset juvenile idiopathic arthritis (SoJIA) (Journal article)
Hedrich, C. M., Bruck, N., Fiebig, B., & Gahr, M. (2012). Anakinra: A safe and effective first-line treatment in systemic onset juvenile idiopathic arthritis (SoJIA). RHEUMATOLOGY INTERNATIONAL, 32(11), 3525-3530. doi:10.1007/s00296-011-2249-4DOI: 10.1007/s00296-011-2249-4
cAMP response element modulator α controls <i>IL2</i> and <i>IL17A</i> expression during CD4 lineage commitment and subset distribution in lupus (Journal article)
Hedrich, C. M., Crispin, J. C., Rauen, T., Ioannidis, C., Apostolidis, S. A., Lo, M. S., . . . Tsokos, G. C. (2012). cAMP response element modulator α controls <i>IL2</i> and <i>IL17A</i> expression during CD4 lineage commitment and subset distribution in lupus. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 109(41), 16606-16611. doi:10.1073/pnas.1210129109DOI: 10.1073/pnas.1210129109
Attenuated TLR4/MAPK signaling in monocytes from patients with CRMO results in impaired IL-10 expression (Journal article)
Hofmann, S. R., Morbach, H., Schwarz, T., Roesen-Wolff, A., Girschick, H. J., & Hedrich, C. M. (2012). Attenuated TLR4/MAPK signaling in monocytes from patients with CRMO results in impaired IL-10 expression. CLINICAL IMMUNOLOGY, 145(1), 69-76. doi:10.1016/j.clim.2012.07.012DOI: 10.1016/j.clim.2012.07.012
"Mutation negative" familial cold autoinflammatory syndrome (FCAS) in an 8-year-old boy: clinical course and functional studies (Journal article)
Hedrich, C. M., Bruck, N., Paul, D., Hahn, G., Gahr, M., & Roesen-Wolff, A. (2012). "Mutation negative" familial cold autoinflammatory syndrome (FCAS) in an 8-year-old boy: clinical course and functional studies. RHEUMATOLOGY INTERNATIONAL, 32(9), 2629-2636. doi:10.1007/s00296-011-2019-3DOI: 10.1007/s00296-011-2019-3
Hofmann, S. R., Roesen-Wolff, A., Hahn, G., & Hedrich, C. M. (2012). Update: Cytokine Dysregulation in Chronic Nonbacterial Osteomyelitis (CNO).. International journal of rheumatology, 2012, 310206. doi:10.1155/2012/310206DOI: 10.1155/2012/310206
A novel isoform of the orphan receptor RORγt suppresses IL-17 production in human T cells (Journal article)
Rauen, T., Juang, Y. -T., Hedrich, C. M., Kis-Toth, K., & Tsokos, G. C. (2012). A novel isoform of the orphan receptor RORγt suppresses IL-17 production in human T cells. GENES AND IMMUNITY, 13(4), 346-350. doi:10.1038/gene.2011.85DOI: 10.1038/gene.2011.85
Biological properties and regulation of IL-10 related cytokines and their contribution to autoimmune disease and tissue injury (Journal article)
Hofmann, S. R., Roesen-Wolff, A., Tsokos, G. C., & Hedrich, C. M. (2012). Biological properties and regulation of IL-10 related cytokines and their contribution to autoimmune disease and tissue injury. CLINICAL IMMUNOLOGY, 143(2), 116-127. doi:10.1016/j.clim.2012.02.005DOI: 10.1016/j.clim.2012.02.005
cAMP responsive element modulator (CREM)α induces epigenetic remodeling of IL2 in T lymphocytes from SLE patients (Conference Paper)
Hedrich, C., Rauen, T., & Tsokos, G. (2012). cAMP responsive element modulator (CREM)α induces epigenetic remodeling of IL2 in T lymphocytes from SLE patients. In JOURNAL OF IMMUNOLOGY Vol. 188. Retrieved from https://www.webofscience.com/
Epigenetic patterns in systemic sclerosis and their contribution to attenuated CD70 signaling cascades (Journal article)
Hedrich, C. M., & Rauen, T. (2012). Epigenetic patterns in systemic sclerosis and their contribution to attenuated CD70 signaling cascades. CLINICAL IMMUNOLOGY, 143(1), 1-3. doi:10.1016/j.clim.2012.01.017DOI: 10.1016/j.clim.2012.01.017
cAMP-responsive Element Modulator α (CREMα) Suppresses IL-17F Protein Expression in T Lymphocytes from Patients with Systemic Lupus Erythematosus (SLE) (Journal article)
Hedrich, C. M., Rauen, T., Kis-Toth, K., Kyttaris, V. C., & Tsokos, G. C. (2012). cAMP-responsive Element Modulator α (CREMα) Suppresses IL-17F Protein Expression in T Lymphocytes from Patients with Systemic Lupus Erythematosus (SLE). JOURNAL OF BIOLOGICAL CHEMISTRY, 287(7), 4715-4725. doi:10.1074/jbc.M111.323261DOI: 10.1074/jbc.M111.323261
Increased Expression of SLAM Receptors SLAMF3 and SLAMF6 in Systemic Lupus Erythematosus T Lymphocytes Promotes Th17 Differentiation (Journal article)
Chatterjee, M., Rauen, T., Kis-Toth, K., Kyttaris, V. C., Hedrich, C. M., Terhorst, C., & Tsokos, G. C. (2012). Increased Expression of SLAM Receptors SLAMF3 and SLAMF6 in Systemic Lupus Erythematosus T Lymphocytes Promotes Th17 Differentiation. JOURNAL OF IMMUNOLOGY, 188(3), 1206-1212. doi:10.4049/jimmunol.1102773DOI: 10.4049/jimmunol.1102773
Pilot study: possible association of IL10 promoter polymorphisms with CRMO (Journal article)
Hamel, J., Paul, D., Gahr, M., & Hedrich, C. M. (2012). Pilot study: possible association of IL10 promoter polymorphisms with CRMO. RHEUMATOLOGY INTERNATIONAL, 32(2), 555-556. doi:10.1007/s00296-010-1768-8DOI: 10.1007/s00296-010-1768-8
Role of Human DNA Glycosylase Nei-like 2 (NEIL2) and Single Strand Break Repair Protein Polynucleotide Kinase 3′-Phosphatase in Maintenance of Mitochondrial Genome (Journal article)
Mandal, S. M., Hegde, M. L., Chatterjee, A., Hegde, P. M., Szczesny, B., Banerjee, D., . . . Hazra, T. K. (2012). Role of Human DNA Glycosylase Nei-like 2 (NEIL2) and Single Strand Break Repair Protein Polynucleotide Kinase 3′-Phosphatase in Maintenance of Mitochondrial Genome. JOURNAL OF BIOLOGICAL CHEMISTRY, 287(4), 2819-2829. doi:10.1074/jbc.M111.272179DOI: 10.1074/jbc.M111.272179
Dynamic CpG-DNA Methylation of <i>Il10</i> and <i>Il19</i> in CD4<SUP>+</SUP> T Lymphocytes and Macrophages: Effects on Tissue-Specific Gene Expression (Journal article)
Hofmann, S. R., Moeller, J., Rauen, T., Paul, D., Gahr, M., Roesen-Wolff, Z., . . . Hedrich, C. M. (2012). Dynamic CpG-DNA Methylation of <i>Il10</i> and <i>Il19</i> in CD4<SUP>+</SUP> T Lymphocytes and Macrophages: Effects on Tissue-Specific Gene Expression. KLINISCHE PADIATRIE, 224(2), 53-60. doi:10.1055/s-0031-1291359DOI: 10.1055/s-0031-1291359
2011
Autologous stem cell transplantation in refractory paediatric Wegener's granulomatosis (Journal article)
Hedrich, C. M., Fiebig, B., Bruck, N., Hahn, G., Bornhaeuser, M., Gahr, M., & Suttorp, M. (2011). Autologous stem cell transplantation in refractory paediatric Wegener's granulomatosis. CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, 29(5), 897-898. Retrieved from https://www.webofscience.com/
cAMP-responsive Element Modulator (CREM)α Protein Induces Interleukin 17A Expression and Mediates Epigenetic Alterations at the Interleukin-17A Gene Locus in Patients with Systemic Lupus Erythematosus (Journal article)
Rauen, T., Hedrich, C. M., Juang, Y. -T., Tenbrock, K., & Tsokos, G. C. (2011). cAMP-responsive Element Modulator (CREM)α Protein Induces Interleukin 17A Expression and Mediates Epigenetic Alterations at the Interleukin-17A Gene Locus in Patients with Systemic Lupus Erythematosus. JOURNAL OF BIOLOGICAL CHEMISTRY, 286(50), 43437-43446. doi:10.1074/jbc.M111.299313DOI: 10.1074/jbc.M111.299313
cAMP-responsive Element Modulator (CREM)α Protein Signaling Mediates Epigenetic Remodeling of the Human Interleukin-2 Gene <i>IMPLICATIONS IN SYSTEMIC LUPUS ERYTHEMATOSUS</i> (Journal article)
Hedrich, C. M., Rauen, T., & Tsokos, G. C. (2011). cAMP-responsive Element Modulator (CREM)α Protein Signaling Mediates Epigenetic Remodeling of the Human Interleukin-2 Gene <i>IMPLICATIONS IN SYSTEMIC LUPUS ERYTHEMATOSUS</i>. JOURNAL OF BIOLOGICAL CHEMISTRY, 286(50), 43429-43436. doi:10.1074/jbc.M111.299339DOI: 10.1074/jbc.M111.299339
Chronic non-bacterial osteomyelitis is associated with impaired Sp1 signaling, reduced <i>IL10</i> promoter phosphorylation, and reduced myeloid IL-10 expression (Journal article)
Hofmann, S. R., Schwarz, T., Moeller, J. C., Morbach, H., Schnabel, A., Roesen-Wolff, A., . . . Hedrich, C. M. (2011). Chronic non-bacterial osteomyelitis is associated with impaired Sp1 signaling, reduced <i>IL10</i> promoter phosphorylation, and reduced myeloid IL-10 expression. CLINICAL IMMUNOLOGY, 141(3), 317-327. doi:10.1016/j.clim.2011.08.012DOI: 10.1016/j.clim.2011.08.012
Epigenetic mechanisms in systemic lupus erythematosus and other autoimmune diseases (Journal article)
Hedrich, C. M., & Tsokos, G. C. (2011). Epigenetic mechanisms in systemic lupus erythematosus and other autoimmune diseases. TRENDS IN MOLECULAR MEDICINE, 17(12), 714-724. doi:10.1016/j.molmed.2011.07.005DOI: 10.1016/j.molmed.2011.07.005
Presentations and Treatment of Childhood Scleroderma: Localized Scleroderma, Eosinophilic Fasciitis, Systemic Sclerosis, and Graft-Versus-Host Disease (Journal article)
Hedrich, C. M., Fiebig, B., Hahn, G., Suttorp, M., & Gahr, M. (2011). Presentations and Treatment of Childhood Scleroderma: Localized Scleroderma, Eosinophilic Fasciitis, Systemic Sclerosis, and Graft-Versus-Host Disease. CLINICAL PEDIATRICS, 50(7), 604-614. doi:10.1177/0009922810396546DOI: 10.1177/0009922810396546
Chorioretinitis in a 7-Year-Old African Girl, Probably Related to JSSc Resolving to Methotrexate Therapy (Journal article)
Hedrich, C. M., Leszczynska, A., Hammermann, J., Bau, V., & Gahr, M. (2011). Chorioretinitis in a 7-Year-Old African Girl, Probably Related to JSSc Resolving to Methotrexate Therapy. KLINISCHE PADIATRIE, 223(2), 92-94. doi:10.1055/s-0030-1270438DOI: 10.1055/s-0030-1270438
Early onset systemic lupus erythematosus: differential diagnoses, clinical presentation, and treatment options (Journal article)
Hedrich, C. M., Zappel, H., Straub, S., Laass, M. W., Wieczorek, K., Hahn, G., . . . Gahr, M. (2011). Early onset systemic lupus erythematosus: differential diagnoses, clinical presentation, and treatment options. CLINICAL RHEUMATOLOGY, 30(2), 275-283. doi:10.1007/s10067-010-1576-2DOI: 10.1007/s10067-010-1576-2
Genetic Variation and Epigenetic Patterns in Autoimmunity (Journal article)
Hedrich, C. M. (2011). Genetic Variation and Epigenetic Patterns in Autoimmunity. Journal of Genetic Syndromes & Gene Therapy, 02(01). doi:10.4172/2157-7412.10000e2DOI: 10.4172/2157-7412.10000e2
MENINGOENCEPHALITIS CAUSED BY VARICELLA-ZOSTER VIRUS REACTIVATION IN A CHILD WITH DOMINANT PARTIAL INTERFERON-GAMMA RECEPTOR-1 DEFICIENCY (Journal article)
Roesler, J., Hedrich, C., Laass, M. W., Heyne, K., & Roesen-Wolff, A. (2011). MENINGOENCEPHALITIS CAUSED BY VARICELLA-ZOSTER VIRUS REACTIVATION IN A CHILD WITH DOMINANT PARTIAL INTERFERON-GAMMA RECEPTOR-1 DEFICIENCY. PEDIATRIC INFECTIOUS DISEASE JOURNAL, 30(3), 265-266. doi:10.1097/INF.0b013e3181f6f78aDOI: 10.1097/INF.0b013e3181f6f78a
Mixed multilineage chimerism and course of globoid leukodystrophy after allogeneic transplantation of CD3/CD19 depleted haematopoietic cells (Conference Paper)
Link, C., Bornhaeuser, M., Thiede, C., Parmentier, S., Hedrich, C., Knoefler, R., . . . Suttorp, M. (2011). Mixed multilineage chimerism and course of globoid leukodystrophy after allogeneic transplantation of CD3/CD19 depleted haematopoietic cells. In BONE MARROW TRANSPLANTATION Vol. 46 (pp. S162). Retrieved from https://www.webofscience.com/
Mixed multilineage chimerism and course of globoid leukodystrophy after allogeneic transplantation of CD3/CD19 depleted hematopoietic cells (Conference Paper)
Link, C., Bornhaeuser, M., Thiede, C., Parmentier, S., Hedrich, C., Knoefler, R., . . . Suttorp, M. (2011). Mixed multilineage chimerism and course of globoid leukodystrophy after allogeneic transplantation of CD3/CD19 depleted hematopoietic cells. In ONKOLOGIE Vol. 34 (pp. 270). Retrieved from https://www.webofscience.com/
2010
<i>IL10</i> promoter polymorphisms are associated with systemic onset juvenile idiopathic arthritis (SoJIA) (Journal article)
Moeller, J. C., Paul, D., Ganser, G., Range, U., Gahr, M., Kelsch, R., . . . Hedrich, C. M. (2010). <i>IL10</i> promoter polymorphisms are associated with systemic onset juvenile idiopathic arthritis (SoJIA). CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, 28(6), 912-918. Retrieved from https://www.webofscience.com/
Dynamic DNA methylation patterns across the mouse and human <i>IL10</i> genes during CD4<SUP>+</SUP> T cell activation, influence of IL-27 (Journal article)
Hedrich, C. M., Ramakrishnan, A., Dabitao, D., Wang, F., Ranatunga, D., & Bream, J. H. (2010). Dynamic DNA methylation patterns across the mouse and human <i>IL10</i> genes during CD4<SUP>+</SUP> T cell activation, influence of IL-27. MOLECULAR IMMUNOLOGY, 48(1-3), 73-81. doi:10.1016/j.molimm.2010.09.009DOI: 10.1016/j.molimm.2010.09.009
Cell type-specific regulation of IL-10 expression in inflammation and disease (Journal article)
Hedrich, C. M., & Bream, J. H. (2010). Cell type-specific regulation of IL-10 expression in inflammation and disease. IMMUNOLOGIC RESEARCH, 47(1-3), 185-206. doi:10.1007/s12026-009-8150-5DOI: 10.1007/s12026-009-8150-5
Effects of cell-type specific hIL-10 expression on disease susceptibility (Conference Paper)
Ranatunga, D., Hedrich, C., Wang, F., McVicar, D., Norwak, N., Joshi, T., . . . Bream, J. (2010). Effects of cell-type specific hIL-10 expression on disease susceptibility. In JOURNAL OF IMMUNOLOGY Vol. 184. Retrieved from https://www.webofscience.com/
DNA methylation in T cell specific <i>IL10</i> regulation (Conference Paper)
Hedrich, C. M., Ramakrishnan, A., Ranatunga, D., & Bream, J. H. (2010). DNA methylation in T cell specific <i>IL10</i> regulation. In EUROPEAN JOURNAL OF PEDIATRICS Vol. 169 (pp. 383-384). Retrieved from https://www.webofscience.com/
2009
A human <i>IL10</i> BAC transgene reveals tissue-specific control of IL-10 expression and alters disease outcome (Journal article)
Ranatunga, D., Hedrich, C. M., Wang, F., McVicar, D. W., Nowak, N., Joshi, T., . . . Bream, J. H. (2009). A human <i>IL10</i> BAC transgene reveals tissue-specific control of IL-10 expression and alters disease outcome. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 106(40), 17123-17128. doi:10.1073/pnas.0904955106DOI: 10.1073/pnas.0904955106
A human IL10 BAC transgene reveals tissue-specific control of IL-10 expression: implications on disease outcomes (Conference Paper)
Bream, J. H., Ranatunga, D., Hedrich, C. M., Wang, F., McVicar, D. W., Nowak, N., . . . Staeger, S. (2009). A human IL10 BAC transgene reveals tissue-specific control of IL-10 expression: implications on disease outcomes. In CYTOKINE Vol. 48 (pp. 74-75). doi:10.1016/j.cyto.2009.07.250DOI: 10.1016/j.cyto.2009.07.250
Autosomal Dominant Neurohypophyseal Diabetes Insipidus in Two Families (Journal article)
Hedrich, C. M., Zachurzok-Buczynska, A., Gawlik, A., Russ, S., Hahn, G., Koehler, K., . . . Huebner, A. (2009). Autosomal Dominant Neurohypophyseal Diabetes Insipidus in Two Families. HORMONE RESEARCH, 71(2), 111-119. doi:10.1159/000183900DOI: 10.1159/000183900
2008
Good response to IL-1ß blockade by anakinra in a 23-year-old CINCA/NOMID patient without mutations in the <i>CIAS1</i> gene.: Cytokine profiles and functional studies (Journal article)
Hedrich, C. M., Fiebig, B., Sallmann, S., Bruck, N., Hahn, G., Roesler, J., . . . Gahr, M. (2008). Good response to IL-1ß blockade by anakinra in a 23-year-old CINCA/NOMID patient without mutations in the <i>CIAS1</i> gene.: Cytokine profiles and functional studies. SCANDINAVIAN JOURNAL OF RHEUMATOLOGY, 37(5), 385-389. doi:10.1080/03009740801978889DOI: 10.1080/03009740801978889
Chilblain lupus erythematosus-a review of literature. (Journal article)
Hedrich, C. M., Fiebig, B., Hauck, F. H., Sallmann, S., Hahn, G., Pfeiffer, C., . . . Gahr, M. (2008). Chilblain lupus erythematosus-a review of literature.. Clinical rheumatology, 27(10), 1341. doi:10.1007/s10067-008-0975-0DOI: 10.1007/s10067-008-0975-0
Stat4-dependent, T-bet-independent regulation of IL-10 in NK cells (Journal article)
Grant, L. R., Yao, Z. -J., Hedrich, C. M., Wang, F., Moorthy, A., Wilson, K., . . . Bream, J. H. (2008). Stat4-dependent, T-bet-independent regulation of IL-10 in NK cells. GENES AND IMMUNITY, 9(4), 316-327. doi:10.1038/gene.2008.20DOI: 10.1038/gene.2008.20
Osteoid osteomas of the fingers: an atypical localization? Two case reports and a review of the literature (Journal article)
Hedrich, C. M., Fiebig, B., Sallmann, S., Bruck, N., Thielemann, F., Hahn, G., . . . Gahr, M. (2008). Osteoid osteomas of the fingers: an atypical localization? Two case reports and a review of the literature. ZEITSCHRIFT FUR RHEUMATOLOGIE, 67(2), 145-+. doi:10.1007/s00393-008-0262-0DOI: 10.1007/s00393-008-0262-0
Chilblain lupus erythematosus - a review of literature (Journal article)
Hedrich, C. M., Fiebig, B., Hauck, F. H., Sallmann, S., Hahn, G., Pfeiffer, C., . . . Gahr, M. (2008). Chilblain lupus erythematosus - a review of literature. CLINICAL RHEUMATOLOGY, 27(8), 949-954. doi:10.1007/s10067-008-0942-9DOI: 10.1007/s10067-008-0942-9
Good response to IL-1β blockade by anakinra in a CINCA/NOMID patient without CIAS1 mutations (Conference Paper)
Hedrich, C., Fiebig, B., Bruck, N., Hahn, G., Roesler, J., Roesen-Wolff, A., . . . Gahr, M. (2008). Good response to IL-1β blockade by anakinra in a CINCA/NOMID patient without CIAS1 mutations. In CLINICAL AND EXPERIMENTAL RHEUMATOLOGY Vol. 26 (pp. 203-204). Retrieved from https://www.webofscience.com/
Interaction of cells involved in wound repair with different fibrin sealant matrices (Conference Paper)
Macasev, D., Barry, J., Hedrich, C., Lintl, P., Bittner, M., Gulle, H., & Goppelt, A. (2008). Interaction of cells involved in wound repair with different fibrin sealant matrices. In TISSUE ENGINEERING PART A Vol. 14 (pp. 871). Retrieved from https://www.webofscience.com/
2007
Wegener's granulomatosis in pediatric patients (Journal article)
Fiebig, B., Hedrich, C. M., Heubner, G., & Gahr, M. (2007). Wegener's granulomatosis in pediatric patients. KLINISCHE PADIATRIE, 219(6), 348-354. doi:10.1055/s-2007-971047DOI: 10.1055/s-2007-971047
Chilblain Lupus erythematosus - Diagnosis and therapy with a 13-year old patients (Conference Paper)
Hedrich, C. M., Fiebig, B., Sallmann, S., Bruck, N., Hahn, G., Pfeiffer, C., . . . Gahr, M. (2007). Chilblain Lupus erythematosus - Diagnosis and therapy with a 13-year old patients. In ZEITSCHRIFT FUR RHEUMATOLOGIE Vol. 66 (pp. 633). Retrieved from https://www.webofscience.com/
Osteoid osteoma of finger - A atypical localisation? Conservative therapy approach! (Conference Paper)
Hedrich, C. M., Fiebig, B., Sallmann, S., Bruck, N., Thielemann, F., Hahn, G., . . . Gahr, M. (2007). Osteoid osteoma of finger - A atypical localisation? Conservative therapy approach!. In ZEITSCHRIFT FUR RHEUMATOLOGIE Vol. 66 (pp. 633). Retrieved from https://www.webofscience.com/
Sclerodermiform skin changes in infancy (Conference Paper)
Fiebig, B., Hedrich, C. M., Sallmann, S., Bruck, N., Pfeiffer, C., Hahn, G., . . . Gahr, M. (2007). Sclerodermiform skin changes in infancy. In ZEITSCHRIFT FUR RHEUMATOLOGIE Vol. 66 (pp. 629-630). Retrieved from https://www.webofscience.com/
Successful therapy with a 23 year old CINCA patient with anakinra: Course depending on cytokine profiles and functional analysis (Conference Paper)
Hedrich, C. M., Fiebig, B., Sallmann, S., Bruck, N., Hahn, G., Heubner, G., & Gahr, M. (2007). Successful therapy with a 23 year old CINCA patient with anakinra: Course depending on cytokine profiles and functional analysis. In ZEITSCHRIFT FUR RHEUMATOLOGIE Vol. 66 (pp. 632-633). Retrieved from https://www.webofscience.com/
Takayasu arteritis: Diagnosis, treatment and progression (Conference Paper)
Hedrich, C. M., Fiebig, B., Sallmann, S., Mayer, B., Hahn, G., & Gahr, M. (2007). Takayasu arteritis: Diagnosis, treatment and progression. In KLINISCHE PADIATRIE Vol. 219 (pp. 115). Retrieved from https://www.webofscience.com/
2006
Systemic lupus erythematosus in children and adolescents (Journal article)
Sallmann, S., Fiebig, B., Hedrich, C. M., Heubner, G., & Gahr, M. (2006). Systemic lupus erythematosus in children and adolescents. ZEITSCHRIFT FUR RHEUMATOLOGIE, 65(7), 576-+. doi:10.1007/s00393-006-0115-7DOI: 10.1007/s00393-006-0115-7
2005
Diclofenac inhibits proliferation and matrix formation of osteoblast cells (Journal article)
Kaspar, D., Hedrich, C. M., Schmidt, C., Liedert, A., Claes, L. E., & Ignatius, A. A. (2005). Diclofenac inhibits proliferation and matrix formation of osteoblast cells. UNFALLCHIRURG, 108(1), 18-+. doi:10.1007/s00113-004-0858-zDOI: 10.1007/s00113-004-0858-z
Orbitale Myositis beim Kind – ein Fallbericht (Journal article)
Schreiber, J., Pollack, K., Hedrich, C. M., & Pillunat, L. E. (n.d.). Orbitale Myositis beim Kind – ein Fallbericht. Klinische Monatsblätter für Augenheilkunde, 222(S 4). doi:10.1055/s-2005-922186DOI: 10.1055/s-2005-922186
Undated
