Prof Carrol Gamble BSc PhD

Professor of Medical Statistics Biostatistics

    Research

    Research Group Membership
    Research Grants

    Pilot-Education and training for recruiters to randomised trials

    HEALTH RESEARCH BOARD (IRELAND)

    January 2018 - December 2020

    Extending ORRCA to create a central resource for retention research within clinical trials (ORRCA 2)

    MEDICAL RESEARCH COUNCIL (MRC)

    June 2018 - November 2019

    COPE The Carboprost or Oxytocin Postpartum haemorrhage Effectiveness Study

    DEPARTMENT OF HEALTH (UK) (NIHR)

    September 2017 - August 2021

    MIROR Methods in research on research

    EUROPEAN COMMISSION

    March 2016 - February 2020

    From evidence to guidance on patient recruitment to clinical research in intensive care units.

    ECONOMIC AND SOCIAL RESEARCH COUNCIL (ESRC)

    September 2016 - May 2020

    Methods for Patient and Public Involvement in Clinical Trials: A Research Priority and Agenda Setting Exercise.

    MEDICAL RESEARCH COUNCIL (MRC)

    October 2015 - May 2017

    TOPS: Timing of Primary Surgery for Cleft Palate (renewal)

    NATIONAL INSTITUTES OF HEALTH (NIH) (USA)

    July 2016 - June 2020

    The TRECA study: TRials Engagement in Children and Adolescents

    DEPARTMENT OF HEALTH (UK) (NIHR)

    February 2016 - July 2020

    How does treatment with thyroxine for 6 weeks postnatally given to preterm infants born under 28 weeks gestation affect the hypothalamic-pituitary adrenal axix, somatic growth, meylination of white matter and the volumes of key brain structures? An exploratory randomised double blinded placebo controlled clinical trial

    MEDICAL RESEARCH COUNCIL (MRC)

    March 2007 - May 2010

    Development of an interactive website for outcome reporting bias research

    MEDICAL RESEARCH COUNCIL (MRC)

    July 2015 - June 2016

    Radiation versus observation following surgical resection of Atypical Meningioma: a randomised controlled trial (The ROAM trial).

    DEPARTMENT OF HEALTH (UK) (NIHR)

    November 2014 - March 2026

    ORBIT II: Outcome Reporting Bias In Trials

    MEDICAL RESEARCH COUNCIL (MRC)

    June 2012 - December 2013

    SLEEPS: Safety profiLe, Efficacy and Equivalence in Paediatric intensive care Sedation: A Comparison of Clonidine and Midazolam

    DEPARTMENT OF HEALTH (UK) (NIHR)

    July 2007 - November 2012

    Understanding the process and impact of within-study selective reporting bias.

    MEDICAL RESEARCH COUNCIL (MRC)

    October 2006 - November 2008

    Duration of intravenous antibiotic therapy for children with acute osteomyelitis or septic arthritis: a feasibility study

    DEPARTMENT OF HEALTH (UK) (NIHR)

    October 2012 - May 2015

    Evaluation of Corticosteroid therapy in Childhood Severe Sepsis- a randomised pilot study

    MENINGITIS RESEARCH FOUNDATION (UK)

    October 2013 - June 2014

    North West Hub for Trial Methodology Research (NWHTMR)

    MEDICAL RESEARCH COUNCIL (MRC)

    October 2008 - August 2014

    PREVAIL-Preventing infection using antibiotic impregnated long lines

    DEPARTMENT OF HEALTH (UK) (NIHR), UNIVERSITY COLLEGE LONDON (UK)

    June 2014 - August 2019

    StePS study

    MENINGITIS RESEARCH FOUNDATION (UK)

    October 2007 - April 2013

    A pragmatic randomised controlled trial of intravenous levetiracetam versus intravenous phenytoin in terminating acute, prolonged tonic-clonic seizures including convulsive status epilepticus in children, the 'EcLIPSE' Study: Emergency treatment with Levetiracetam or Phenytoin in Status Epilepticus

    DEPARTMENT OF HEALTH (UK) (NIHR)

    June 2014 - July 2019

    Losing the losses: understanding the reasons for attrition in randomised trials and developing the evidence to prevent it

    MEDICAL RESEARCH COUNCIL (MRC)

    October 2013 - July 2015

    Onabotulinium toxin-A versus extended release tolterodine in the management of idiopathic overactive bladder in children: A pilot randomised controlled trial OVERT

    DEPARTMENT OF HEALTH (UK) (NIHR)

    July 2014 - August 2018

    Healing Foundation Clinical Trials Unit

    THE SCAR FREE FOUNDATION

    June 2011 - September 2020

    Establishing a database of statistical expertise to support clinical trial oversight committees and develop capacity

    MEDICAL RESEARCH COUNCIL (MRC)

    April 2014 - September 2015

    TP 165 feasilbility study of enhanced relapse prevention by key workers for people diagnosed with Bipolar Disorder.

    MEDICAL RESEARCH COUNCIL (MRC)

    January 2005 - January 2007

    The British Antibiotic and Silver Impregnated Catheters for ventriculoperitoneal Shunts multi-centre randomised controlled trial (The BASICS trial)

    DEPARTMENT OF HEALTH (UK) (NIHR)

    June 2012 - February 2019

    Training key workers to offer enhanced relapse prevention to people with bipolar disorder and their relatives within an NHS setting.

    MERSEY CARE NHS TRUST (UK)

    September 2004 - August 2007

    Trial steering committees for randomised controlled trials: Updating and redeveloping guidance and terms of reference, informed by current practice and experience

    MEDICAL RESEARCH COUNCIL (MRC)

    October 2012 - September 2014

    Clinical trial monitoring: establishing best UK practice?

    MEDICAL RESEARCH COUNCIL (MRC)

    September 2011 - May 2013

    MOMENT The management of otitis media with effusion (OME) in children with cleft palate

    CENTRAL MANCHESTER TEACHING HOSPITALS (UK)

    August 2012 - August 2013

    Development of guidance for statistical analysis plans for clinical trials

    MEDICAL RESEARCH COUNCIL (MRC)

    April 2014 - December 2016

    Consolidating guidelines for the prevention, detection and appraisal of reporting biases in clinical trials

    MEDICAL RESEARCH COUNCIL (MRC)

    May 2012 - October 2013

    Medicines for Children Research Network Clinical Trials Unit

    DEPARTMENT OF HEALTH (UK) (NIHR)

    April 2010 - March 2015

    Development of a central resource for research in recruitment in clinical trials

    MEDICAL RESEARCH COUNCIL (MRC)

    March 2014 - November 2018

    Use of the electronic health record in the design and conduct of clinical trials

    MEDICAL RESEARCH COUNCIL (MRC)

    November 2013 - September 2016

    Research Collaborations

    Health Research Board Trials Methodology Research Network in Ireland

    External

    Health Research Board Trials Methodology Research Network in Ireland, www.hrb-tmrn.ie – adding value to areas of common scientific interest and training;

    MRC Trials Methodology Research Partnership (TMRP)

    External

    The TMRP brings together a number of networks, institutions and partners working in trials and trials methodology research.The TMRP builds on the achievements of the MRC Hubs for Trials Methodology Research Network to make continued progress in advancing trial methodology, developing capacity and further reducing research waste.
    https://www.methodologyhubs.mrc.ac.uk/about/tmrp/