Dr Anna Auer-Fowler

Health Data Science

    Publications

    2021

    Classification of intestinal T cell receptor repertoires using machine learning methods can identify patients with coeliac disease regardless of dietary gluten status (Journal article)

    Foers, A. D., Shoukat, M. S., Welsh, O. E., Donovan, K., Petry, R., Evans, S. C., . . . Soilleux, E. J. (n.d.). Classification of intestinal T cell receptor repertoires using machine learning methods can identify patients with coeliac disease regardless of dietary gluten status. The Journal of Pathology. doi:10.1002/path.5592

    DOI: 10.1002/path.5592

    Use of machine learning to identify a T cell response to SARS-CoV-2. (Journal article)

    Shoukat, M. S., Foers, A. D., Woodmansey, S., Evans, S. C., Fowler, A., & Soilleux, E. J. (2021). Use of machine learning to identify a T cell response to SARS-CoV-2.. Cell reports. Medicine, 2(2), 100192. doi:10.1016/j.xcrm.2021.100192

    DOI: 10.1016/j.xcrm.2021.100192

    2020

    Predicting the animal hosts of coronaviruses from compositional biases of spike protein and whole genome sequences through machine learning (Journal article)

    Brierley, L., & Fowler, A. (2020). Predicting the animal hosts of coronaviruses from compositional biases of spike protein and whole genome sequences through machine learning. doi:10.1101/2020.11.02.350439

    DOI: 10.1101/2020.11.02.350439

    Statistics at the zoo (Journal article)

    Holmes, L., Edwards, K., Moss, A., Tollington, S., Fowler, A., Hughes, D., & Sudell, M. (2020). Statistics at the zoo. Significance, 17(5), 26-29. doi:10.1111/1740-9713.01446

    DOI: 10.1111/1740-9713.01446

    Inferring B cell specificity for vaccines using a Bayesian mixture model (Journal article)

    Fowler, A., Galson, J. D., Truck, J., Kelly, D. F., & Lunter, G. (2020). Inferring B cell specificity for vaccines using a Bayesian mixture model. BMC GENOMICS, 21(1). doi:10.1186/s12864-020-6571-7

    DOI: 10.1186/s12864-020-6571-7

    2019

    A Novel Artificial Intelligence Based Approach to the Diagnosis of Coeliac Disease, Based on T-Cell Receptor Repertoires (Conference Paper)

    Fowler, A., Shoukat, M. S., Welsh, O. E., Donovan, K., & Soilleux, E. J. (2019). A Novel Artificial Intelligence Based Approach to the Diagnosis of Coeliac Disease, Based on T-Cell Receptor Repertoires. In JOURNAL OF PATHOLOGY Vol. 249 (pp. S21). Retrieved from http://gateway.webofknowledge.com/

    2018

    Computer-implemented method and system for determining a disease status of a subject from immune-receptor sequencing data (Patent)

    Soilleux, E., & Auer-Fowler, A. H. M. (2018, November 5). WO 2019/086900 A1, Computer-implemented method and system for determining a disease status of a subject from immune-receptor sequencing data.

    2016

    Accurate clinical detection of exon copy number variants in a targeted NGS panel using DECoN. (Journal article)

    Fowler, A., Mahamdallie, S., Ruark, E., Seal, S., Ramsay, E., Clarke, M., . . . Rahman, N. (2016). Accurate clinical detection of exon copy number variants in a targeted NGS panel using DECoN.. Wellcome open research, 1, 20. doi:10.12688/wellcomeopenres.10069.1

    DOI: 10.12688/wellcomeopenres.10069.1

    B-cell repertoire dynamics after sequential hepatitis B vaccination and evidence for cross-reactive B-cell activation (Journal article)

    Galson, J. D., Trück, J., Clutterbuck, E. A., Fowler, A., Cerundolo, V., Pollard, A. J., . . . Kelly, D. F. (2016). B-cell repertoire dynamics after sequential hepatitis B vaccination and evidence for cross-reactive B-cell activation. Genome Medicine, 8(1). doi:10.1186/s13073-016-0322-z

    DOI: 10.1186/s13073-016-0322-z

    The Diversity and Molecular Evolution of B-Cell Receptors during Infection (Journal article)

    Hoehn, K. B., Fowler, A., Lunter, G., & Pybus, O. G. (2016). The Diversity and Molecular Evolution of B-Cell Receptors during Infection. MOLECULAR BIOLOGY AND EVOLUTION, 33(5), 1147-1157. doi:10.1093/molbev/msw015

    DOI: 10.1093/molbev/msw015

    Bayesian Classification of Vaccine-Specific B-Cells from Repertoire Sequencing Data (Conference Paper)

    Fowler, A., & Lunter, G. (2016). Bayesian Classification of Vaccine-Specific B-Cells from Repertoire Sequencing Data. In HUMAN HEREDITY Vol. 81 (pp. 234). Retrieved from http://gateway.webofknowledge.com/

    2015

    Analysis of B Cell Repertoire Dynamics Following Hepatitis B Vaccination in Humans, and Enrichment of Vaccine-specific Antibody Sequences (Journal article)

    Galson, J. D., Trueck, J., Fowler, A., Clutterbuck, E. A., Muenz, M., Cerundolo, V., . . . Kelly, D. F. (2015). Analysis of B Cell Repertoire Dynamics Following Hepatitis B Vaccination in Humans, and Enrichment of Vaccine-specific Antibody Sequences. EBioMedicine, 2(12), 2070-2079. doi:10.1016/j.ebiom.2015.11.034

    DOI: 10.1016/j.ebiom.2015.11.034

    BCR repertoire sequencing: different patterns of B-cell activation after two Meningococcal vaccines (Journal article)

    Galson, J. D., Clutterbuck, E. A., Trueck, J., Ramasamy, M. N., Muenz, M., Fowler, A., . . . Kelly, D. F. (2015). BCR repertoire sequencing: different patterns of B-cell activation after two Meningococcal vaccines. IMMUNOLOGY AND CELL BIOLOGY, 93(10), 885-895. doi:10.1038/icb.2015.57

    DOI: 10.1038/icb.2015.57

    In-depth assessment of within-individual and inter-individual variation in the B cell receptor repertoire (Journal article)

    Galson, J. D., Trueck, J., Fowler, A., Muenz, M., Cerundolo, V., Pollard, A. J., . . . Kelly, D. F. (2015). In-depth assessment of within-individual and inter-individual variation in the B cell receptor repertoire. FRONTIERS IN IMMUNOLOGY, 6. doi:10.3389/fimmu.2015.00531

    DOI: 10.3389/fimmu.2015.00531

    2013

    DYNAMIC BAYESIAN CLUSTERING (Journal article)

    Fowler, A., Menon, V., & Heard, N. A. (2013). DYNAMIC BAYESIAN CLUSTERING. JOURNAL OF BIOINFORMATICS AND COMPUTATIONAL BIOLOGY, 11(5). doi:10.1142/S0219720013420018

    DOI: 10.1142/S0219720013420018

    Dynamic Bayesian clustering of gene expression data (Conference Paper)

    Fowler, A., & Heard, N. A. (2013). Dynamic Bayesian clustering of gene expression data. In 5th International Conference on Bioinformatics and Computational Biology 2013, BICoB 2013 (pp. 165-170).

    2012

    On two-way Bayesian agglomerative clustering of gene expression data (Journal article)

    Fowler, A., & Heard, N. A. (2012). On two-way Bayesian agglomerative clustering of gene expression data. Statistical Analysis and Data Mining: The ASA Data Science Journal, 5(5), 463-476. doi:10.1002/sam.11162

    DOI: 10.1002/sam.11162