Magnetic Resonance Imaging and Spectroscopy
The Centre has a high-resolution 9.4 T Bruker Biospec 94/20 USR horizontal bore MR imaging scanner. It is specifically geared for small animal imaging and spectroscopy studies as well for high-resolution imaging of ex vivo and non-biological samples. Besides 1H MRI and MRS, the scanner can also be used for observing other nuclei such as 13C, 31P, 23Na, and 19F.
Currently active projects:
- High resolution MR microscopy for MR phenotyping of genetic models;
- In vivo cell tracking for assessing the safety and efficacy of cell therapies;
- Non-invasive measurement of blood flow in kidneys, brain and tumours;
- Measuring tissue metabolism in vivo (MR spectroscopy, chemical shift imaging) in liver and brain tumours;
- Diffusion tensor imaging (DTI) in brain tumours and tissue phenotyping;
- Cardiac imaging;
- MR relaxometry using T1, T2 mapping for contrast agent characterization.
High-resolution three-dimensional image of a brain
Three-dimensional image of a kidney showing stem cells as dark spots
Short-axis view of the motion of a heart over one cardiac cycle