Expertise & Capabilities
The Department of Gastroenterology, provides excellent opportunities for laboratory and clinical research focusing on the pathogenesis of diseases of the gastrointestinal tract in humans and animals. The high quality of our research was specifically commented on in the 2008 Research Assessment Exercise and we have current funding from sources including MRC, BBSRC, Wellcome Trust, EU-FP7 framework, NIHR, AICR and CRUK. Our focus is on “translational” research that will take advances in basic medical research out of the laboratory and into the hospital ‘from the bench to bedside’ in order to improve the health and welfare of people world-wide.
Our research expertise is in the following areas:
- Gastrointestinal cancers - molecular pathogenesis; regulation of apoptosis in the GI tract; the gastrin family of peptides; epithelial glycobiology; development of biomarkers
- Inflammatory Bowel Disease (IBD) – role of bacterial factors; the development and assessment of novel therapies
- GI Infections and bacteraemia
- The Health Economics of Gastrointestinal Disease
- Gut Microbiota & Volatile Organic Compounds in GI disease.
We employ the whole range of cutting-edge experimental techniques from mechanistic studies involving cell-lines and gastrointestinal tissues through to patient studies and clinical trials.