Photo of Dr Michael Berenbrink

Dr Michael Berenbrink Ph.D.

Senior Lecturer Evolution, Ecology and Behaviour

    Publications

    2019

    ATP-induced reversed thermal sensitivity of O2 binding in both major haemoglobin polymorphs of the non-endothermic Atlantic cod, Gadus morhua. (Journal article)

    Nelson, C., Barlow, S. L., & Berenbrink, M. (2019). ATP-induced reversed thermal sensitivity of O-2 binding in both major haemoglobin polymorphs of the non-endothermic Atlantic cod, Gadus morhua. JOURNAL OF EXPERIMENTAL BIOLOGY, 222(12). doi:10.1242/jeb.200279

    DOI: 10.1242/jeb.200279

    Body condition impacts blood and muscle oxygen storage capacity of free-living beluga whales (Delphinapterus leucas). (Journal article)

    Choy, E. S., Campbell, K. L., Berenbrink, M., Roth, J. D., & Loseto, L. L. (2019). Body condition impacts blood and muscle oxygen storage capacity of free-living beluga whales (Delphinapterus leucas). JOURNAL OF EXPERIMENTAL BIOLOGY, 222(11). doi:10.1242/jeb.191916

    DOI: 10.1242/jeb.191916

    Regulation of erythrocyte function: Multiple evolutionary solutions for respiratory gas transport and its regulation in fish. (Journal article)

    Nikinmaa, M., Berenbrink, M., & Brauner, C. J. (2019). Regulation of erythrocyte function: Multiple evolutionary solutions for respiratory gas transport and its regulation in fish.. Acta physiologica (Oxford, England), 227(2), e13299. doi:10.1111/apha.13299

    DOI: 10.1111/apha.13299

    2017

    Extreme anoxia tolerance in crucian carp and goldfish through neofunctionalization of duplicated genes creating a new ethanol-producing pyruvate decarboxylase pathway (Journal article)

    Fagernes, C. E., Stenslokken, K. -O., Rohr, S. K., Berenbrink, M., Ellefsen, S., & Nilsson, G. E. (2017). Extreme anoxia tolerance in crucian carp and goldfish through neofunctionalization of duplicated genes creating a new ethanol-producing pyruvate decarboxylase pathway. SCIENTIFIC REPORTS, 7. doi:10.1038/s41598-017-07385-4

    DOI: 10.1038/s41598-017-07385-4

    Life on the edge: O-2 binding in Atlantic cod red blood cells near their southern distribution limit is not sensitive to temperature or haemoglobin genotype (Journal article)

    Barlow, S. L., Metcalfe, J., Righton, D. A., & Berenbrink, M. (2017). Life on the edge: O-2 binding in Atlantic cod red blood cells near their southern distribution limit is not sensitive to temperature or haemoglobin genotype. JOURNAL OF EXPERIMENTAL BIOLOGY, 220(3), 414-424. doi:10.1242/jeb.141044

    DOI: 10.1242/jeb.141044

    2016

    Marine Genomics Special issue "Genome-powered perspectives in integrative physiology and evolutionary biology" (Edited special journal issue)

    Marine Genomics Special issue "Genome-powered perspectives in integrative physiology and evolutionary biology" (2016). (Vol. 30).

    DOI: 10.1016/j.margen.2016.11.003

    Temperature sensitivity of red blood cell physiology in Atlantic cod, Gadus morhua: Comparative, molecular, evolutionary and environmental aspects (Thesis / Dissertation)

    Barlow, S. L. (2016, March 31). Temperature sensitivity of red blood cell physiology in Atlantic cod, Gadus morhua: Comparative, molecular, evolutionary and environmental aspects.

    2015

    Gene Turnover in the Avian Globin Gene Families and Evolutionary Changes in Hemoglobin Isoform Expression (Journal article)

    Opazo, J. C., Hoffmann, F. G., Natarajan, C., Witt, C. C., Berenbrink, M., & Storz, J. F. (2015). Gene Turnover in the Avian Globin Gene Families and Evolutionary Changes in Hemoglobin Isoform Expression. MOLECULAR BIOLOGY AND EVOLUTION, 32(4), 871-887. doi:10.1093/molbev/msu341

    DOI: 10.1093/molbev/msu341

    2013

    Evolution of Mammalian Diving Capacity Traced by Myoglobin Net Surface Charge (Journal article)

    Mirceta, S., Signore, A. V., Burns, J. M., Cossins, A. R., Campbell, K. L., & Berenbrink, M. (2013). Evolution of Mammalian Diving Capacity Traced by Myoglobin Net Surface Charge. Science, 340(6138), 1234192. doi:10.1126/science.1234192

    DOI: 10.1126/science.1234192

    Pronounced in vivo hemoglobin polymerization in red blood cells of Gulf toadfish: a general role for hemoglobin aggregation in vertebrate hemoparasite defense? (Journal article)

    Koldkjaer, P., McDonald, M. D., Prior, I., & Berenbrink, M. (2013). Pronounced in vivo hemoglobin polymerization in red blood cells of Gulf toadfish: a general role for hemoglobin aggregation in vertebrate hemoparasite defense?. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY, 305(10), R1190-R1199. doi:10.1152/ajpregu.00246.2013

    DOI: 10.1152/ajpregu.00246.2013

    The foraging behaviour of seabirds: defining and predicting home range areas (Thesis / Dissertation)

    Soanes, L. (n.d.). The foraging behaviour of seabirds: defining and predicting home range areas. (PhD Thesis, University of Liverpool).

    2012

    Functional differentiation of myoglobin isoforms in hypoxia-tolerant carp indicates tissue-specific protective roles (Journal article)

    Helbo, S., Dewilde, S., Williams, D. R., Berghmans, H., Berenbrink, M., Cossins, A. R., & Fago, A. (2012). Functional differentiation of myoglobin isoforms in hypoxia-tolerant carp indicates tissue-specific protective roles. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 302(6), R693-R701. doi:10.1152/ajpregu.00501.2011

    DOI: 10.1152/ajpregu.00501.2011

    Nitrite Regulates Hypoxic Vasodilation via Myoglobin-Dependent Nitric Oxide Generation (Journal article)

    Totzeck, M., Hendgen-Cotta, U. B., Luedike, P., Berenbrink, M., Klare, J. P., Steinhoff, H. -J., . . . Rassaf, T. (2012). Nitrite Regulates Hypoxic Vasodilation via Myoglobin-Dependent Nitric Oxide Generation. Circulation, 126(3), 325-334. doi:10.1161/CIRCULATIONAHA.111.087155

    DOI: 10.1161/CIRCULATIONAHA.111.087155

    2011

    Transport and Exchange of Respiratory Gases in the Blood: Evolution of the Bohr Effect (Chapter)

    Berenbrink, M. (2011). Transport and Exchange of Respiratory Gases in the Blood: Evolution of the Bohr Effect. In A. P. Farrell (Ed.), Encyclopedia of Fish Physiology: From Genome to Environment (pp. 921-928). Amsterdam: Elsevier.

    Transport and Exchange of Respiratory Gases in the Blood: Root Effect: Molecular Basis, Evolution of the Root Effect and Rete Systems (Chapter)

    Berenbrink, M. (2011). Transport and Exchange of Respiratory Gases in the Blood: Root Effect: Molecular Basis, Evolution of the Root Effect and Rete Systems. In A. P. Farrell (Ed.), Encyclopedia of Fish Physiology: From Genome to Environment (pp. 929-934). Amsterdam: Elsevier.

    2010

    Magnitude of the Root effect in red blood cells and haemoglobin solutions of fishes: a tribute to August Krogh (Journal article)

    Berenbrink, M., Koldkjaer, P., Hannah Wright, E., Kepp, O., & José da Silva, A. (2011). Magnitude of the Root effect in red blood cells and haemoglobin solutions of fishes: a tribute to August Krogh. Acta Physiologica, 202(3), 583-592. doi:10.1111/j.1748-1716.2010.02243.x

    DOI: 10.1111/j.1748-1716.2010.02243.x

    2009

    Diverse cell-specific expression of myoglobin isoforms in brain, kidney, gill and liver of the hypoxia-tolerant carp and zebrafish (Journal article)

    Cossins, A. R., Williams, D. R., Foulkes, N. S., Berenbrink, M., & Kipar, A. (2009). Diverse cell-specific expression of myoglobin isoforms in brain, kidney, gill and liver of the hypoxia-tolerant carp and zebrafish. Journal of Experimental Biology, 212(5), 627-638. doi:10.1242/jeb.026286

    DOI: 10.1242/jeb.026286

    Oxygen-dependent ion transport in erythrocytes (Journal article)

    Bogdanova, A., Berenbrink, M., & Nikinmaa, M. (2009). Oxygen-dependent ion transport in erythrocytes. Acta Physiologica, 195(3), 305-319. doi:10.1111/j.1748-1716.2008.01934.x

    DOI: 10.1111/j.1748-1716.2008.01934.x

    2008

    Ancient and modern duplication events and the evolution of stearoyl-CoA desaturases in teleost fishes (Journal article)

    Evans, H., De Tomaso, T., Quail, M., Rogers, J., Gracey, A. Y., Cossins, A. R., & Berenbrink, M. (2008). Ancient and modern duplication events and the evolution of stearoyl-CoA desaturases in teleost fishes. Physiological Genomics, 35(1), 18-29. doi:10.1152/physiolgenomics.90266.2008

    DOI: 10.1152/physiolgenomics.90266.2008

    Evolutionary physiology of oxygen secretion in the eye of fishes of the suborder Notothenioidei (Chapter)

    Verde, C., Berenbrink, M., & di Prisco, G. (2008). Evolutionary physiology of oxygen secretion in the eye of fishes of the suborder Notothenioidei. In M. Bolognesi, G. di Prisco, & C. Verde (Eds.), Dioxygen Binding and Sensing Proteins: A Tribute to Beatrice and Jonathan Wittenberg (Vol. 9, pp. 49-66). Milan: Springer (pp. 49-66).

    Minimal volume regulation after shrinkage of red blood cells from five species of reptiles (Journal article)

    Kristensen, K., Berenbrink, M., Koldkjær, P., Abe, A., & Wang, T. (2008). Minimal volume regulation after shrinkage of red blood cells from five species of reptiles. Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology, 150(1), 46-51. doi:10.1016/j.cbpa.2008.03.002

    DOI: 10.1016/j.cbpa.2008.03.002

    Myoglobins new clothes (News and Views) (Journal article)

    Myoglobins new clothes (News and Views) (2008). Nature, 454(7203), 416-417. doi:10.1038/454416a

    DOI: 10.1038/454416a

    2007

    Gas Transport and Exchange (Chapter)

    Brauner, C. J., & Berenbrink, M. (2007). Gas Transport and Exchange. In D. J. McKenzie, A. P. Farrell, C. J. Brauner, A. P. Farrell, & C. J. Brauner (Eds.), Primitive Fishes (Vol. 26, pp. 213-282). Amsterdam: Elsevier (pp. 213-282).

    Historical reconstructions of evolving physiological complexity: O2 secretion in the eye and swimbladder of fishes (Journal article)

    Berenbrink, M. (2007). Historical reconstructions of evolving physiological complexity: O2 secretion in the eye and swimbladder of fishes. Journal of Experimental Biology, 210(9), 1641-1652. doi:10.1242/jeb.003319

    DOI: 10.1242/jeb.003319

    In vivo red blood cell sickling and mechanism of recovery in whiting, Merlangius merlangus (Journal article)

    Koldkjaer, P., & Berenbrink, M. (2007). In vivo red blood cell sickling and mechanism of recovery in whiting, Merlangius merlangus. Journal of Experimental Biology, 210(19), 3451-3460. doi:10.1242/jeb.008524

    DOI: 10.1242/jeb.008524

    Oxygen-sensitive regulatory volume increase and Na transport in red blood cells from the cane toad, Bufo marinus (Journal article)

    Kristensen, K., Koldkjaer, P., Berenbrink, M., & Wang, T. (2007). Oxygen-sensitive regulatory volume increase and Na transport in red blood cells from the cane toad, Bufo marinus. Journal of Experimental Biology, 210(13), 2290-2299. doi:10.1242/jeb.002824

    DOI: 10.1242/jeb.002824

    2006

    Evolution of vertebrate haemoglobins: Histidine side chains, specific buffer value and Bohr effect (Journal article)

    Berenbrink, M. (2006). Evolution of vertebrate haemoglobins: Histidine side chains, specific buffer value and Bohr effect. Respiratory Physiology & Neurobiology, 154(1-2), 165-184. doi:10.1016/j.resp.2006.01.002

    DOI: 10.1016/j.resp.2006.01.002

    Two different oxygen sensors regulate oxygen-sensitive K + transport in crucian carp red blood cells (Journal article)

    Berenbrink, M., Völkel, S., Koldkjaer, P., Heisler, N., & Nikinmaa, M. (2006). Two different oxygen sensors regulate oxygen-sensitive K + transport in crucian carp red blood cells. The Journal of Physiology, 575(1), 37-48. doi:10.1113/jphysiol.2006.112680

    DOI: 10.1113/jphysiol.2006.112680

    2005

    Evolution of Oxygen Secretion in Fishes and the Emergence of a Complex Physiological System (Journal article)

    Berenbrink, M. (2005). Evolution of Oxygen Secretion in Fishes and the Emergence of a Complex Physiological System. Science, 307(5716), 1752-1757. doi:10.1126/science.1107793

    DOI: 10.1126/science.1107793

    2001

    'Effects of sulfide on K+ flux pathways in red blood cells of crucian carp and rainbow trout' (Journal article)

    Volkel, S., Berenbrink, M., Heisler, N., & Nikinmaa, M. (2001). 'Effects of sulfide on K+ flux pathways in red blood cells of crucian carp and rainbow trout'. Fish Physiology and Biochemistry, 24(3), 213-223. doi:10.1023/A:1014050001585

    DOI: 10.1023/A:1014050001585

    2000

    'Sulphaemoglobin formation in fish: a comparison between the haemoglobin of the sulphide-sensitive rainbow trout (Oncorhynchus mykiss) and of the sulphide-tolerant common carp (Cyprinus carpio)' (Journal article)

    Volkel, S., & Berenbrink, M. (2000). 'Sulphaemoglobin formation in fish: a comparison between the haemoglobin of the sulphide-sensitive rainbow trout (Oncorhynchus mykiss) and of the sulphide-tolerant common carp (Cyprinus carpio)'. Journal of Experimental Biology, 203(6), 1047-1058.

    O 2 -dependent K + fluxes in trout red blood cells: the nature of O 2 sensing revealed by the O 2 affinity, cooperativity and pH dependence of transport (Journal article)

    Berenbrink, M., Völkel, S., Heisler, N., & Nikinmaa, M. (2000). O 2 -dependent K + fluxes in trout red blood cells: the nature of O 2 sensing revealed by the O 2 affinity, cooperativity and pH dependence of transport. The Journal of Physiology, 526(1), 69-80. doi:10.1111/j.1469-7793.2000.t01-1-00069.x

    DOI: 10.1111/j.1469-7793.2000.t01-1-00069.x

    1998

    Physiology and Biochemistry of the Pseudobranch: An Unanswered Question? (Journal article)

    Bridges, C., Berenbrink, M., Müller, R., & Waser, W. (1998). Physiology and Biochemistry of the Pseudobranch: An Unanswered Question?. Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology, 119(1), 67-77. doi:10.1016/S1095-6433(97)00405-4

    DOI: 10.1016/S1095-6433(97)00405-4

    1997

    'Defining the volume dependence of multiple K flux pathways of trout red blood cells' (Journal article)

    Berenbrink, M., Weaver, Y. R., & Cossins, A. R. (1997). 'Defining the volume dependence of multiple K flux pathways of trout red blood cells'. American Journal of Physiology, 272(4), C1099-C1111.

    1994

    'Active Na+-, Cl- - and HCO3- -dependent acid extrusion in Atlantic cod red blood cells in winter activated by hypercapnia' (Journal article)

    Berenbrink, M., & Bridges, C. R. (1994). 'Active Na+-, Cl- - and HCO3- -dependent acid extrusion in Atlantic cod red blood cells in winter activated by hypercapnia'. Journal of Experimental Biology, 192, 239-252.

    'Catecholamine-activated sodium/proton exchange in red blood cells of the marine teleost Gadus morhua' (Journal article)

    Berenbrink, M., & Bridges, C. R. (1994). 'Catecholamine-activated sodium/proton exchange in red blood cells of the marine teleost Gadus morhua'. Journal of Experimental Biology, 192, 253-267.