Dr Lucille Rainbow Ph.D

Research Associate Biochemistry & Systems Biology

Publications

2021

Assessment of the impact of mitochondrial genotype upon drug-induced mitochondrial dysfunction in platelets derived from healthy volunteers (Journal article)

Ball, A. L., Bloch, K. M., Rainbow, L., Liu, X., Kenny, J., Lyon, J. J., . . . Chadwick, A. E. (n.d.). Assessment of the impact of mitochondrial genotype upon drug-induced mitochondrial dysfunction in platelets derived from healthy volunteers. Archives of Toxicology. doi:10.1007/s00204-021-02988-3

DOI: 10.1007/s00204-021-02988-3

2020

Long non-coding RNA dysregulation is a frequent event in non-small cell lung carcinoma pathogenesis (Journal article)

Acha-Sagredo, A., Uko, B., Pantazi, P., Bediaga, N., Moschandrea, C., Rainbow, L., . . . Liloglou, T. (2020). Long non-coding RNA dysregulation is a frequent event in non-small cell lung carcinoma pathogenesis. British Journal of Cancer, 122(7), 1050-1058. doi:10.1038/s41416-020-0742-9

DOI: 10.1038/s41416-020-0742-9

Netazepide Inhibits Expression of Pappalysin 2 in Type 1 Gastric Neuroendocrine Tumors (Journal article)

Lloyd, K. A., Parsons, B. N., Burkitt, M. D., Moore, A. R., Papoutsopoulou, S., Boyce, M., . . . Pritchard, D. M. (2020). Netazepide Inhibits Expression of Pappalysin 2 in Type 1 Gastric Neuroendocrine Tumors. CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY, 10(1), 113-132. doi:10.1016/j.jcmgh.2020.01.010

DOI: 10.1016/j.jcmgh.2020.01.010

Netazepide Inhibits Expression of Pappalysin 2 in Type-1 Gastric Neuroendocrine Tumors (Journal article)

Rainbow, L. (n.d.). Netazepide Inhibits Expression of Pappalysin 2 in Type-1 Gastric Neuroendocrine Tumors. CMGH Cellular and Molecular Gastroenterology and Hepatology. doi:10.1016/j.jcmgh.2020.01.010

DOI: 10.1016/j.jcmgh.2020.01.010

2019

A novel panel of differentially-expressed microRNAs in breast cancer brain metastasis may predict patient survival (Journal article)

Giannoudis, A., Clarke, K., Zakaria, R., Vareslija, D., Farahani, M., Rainbow, L., . . . Palmieri, C. (2019). A novel panel of differentially-expressed microRNAs in breast cancer brain metastasis may predict patient survival. SCIENTIFIC REPORTS, 9. doi:10.1038/s41598-019-55084-z

DOI: 10.1038/s41598-019-55084-z

Endocardium differentiation through Sox17 expression in endocardium precursor cells regulates heart development in mice (Journal article)

Saba, R., Kitajima, K., Rainbow, L., Engert, S., Uemura, M., Ishida, H., . . . Yashiro, K. (2019). Endocardium differentiation through Sox17 expression in endocardium precursor cells regulates heart development in mice. SCIENTIFIC REPORTS, 9. doi:10.1038/s41598-019-48321-y

DOI: 10.1038/s41598-019-48321-y

CD4 T-CELL HLA-U PSEUDOGENE AT BASELINE PREDICTS CLINICAL REMISSION TO ANTI-TNF AGENTS IN ULCERATIVE COLITIS (Conference Paper)

Subramanian, S., Rainbow, L., Gemmell, M., Fang, Y., Haldenby, S., Hough, R., & Probert, C. (2019). CD4 T-CELL HLA-U PSEUDOGENE AT BASELINE PREDICTS CLINICAL REMISSION TO ANTI-TNF AGENTS IN ULCERATIVE COLITIS. In GUT Vol. 68 (pp. A64-A65). doi:10.1136/gutjnl-2019-BSGAbstracts.127

DOI: 10.1136/gutjnl-2019-BSGAbstracts.127

Identification of microRNAs differentially expressed in brain metastasis secondary to breast cancer (Conference Paper)

Giannoudis, A., Clarke, K., Zakaria, R., Vareslija, D., Farahani, M., Rainbow, L., . . . Palmieri, C. (2019). Identification of microRNAs differentially expressed in brain metastasis secondary to breast cancer. In CANCER RESEARCH Vol. 79. doi:10.1158/1538-7445.SABCS18-P6-05-02

DOI: 10.1158/1538-7445.SABCS18-P6-05-02

Characterisation of the NRF2 transcriptional network and its response to chemical insult in primary human hepatocytes: implications for prediction of drug-induced liver injury (Journal article)

Copple, I. M., den Hollander, W., Callegaro, G., Mutter, F. E., Maggs, J. L., Schofield, A. L., . . . Park, B. K. (2019). Characterisation of the NRF2 transcriptional network and its response to chemical insult in primary human hepatocytes: implications for prediction of drug-induced liver injury. Archives of Toxicology, 93, 385-399. doi:10.1007/s00204-018-2354-1

DOI: 10.1007/s00204-018-2354-1

CD4 T-cell transcriptome analysis at baseline predicts clinical remission to anti-TNF agents in ulcerative colitis (UC) (Conference Paper)

Subramanian, S., Rainbow, L., Gemmell, M., Hough, R., Haldenby, S., Gureviciute, A., . . . Probert, C. (2019). CD4 T-cell transcriptome analysis at baseline predicts clinical remission to anti-TNF agents in ulcerative colitis (UC). In JOURNAL OF CROHNS & COLITIS Vol. 13 (pp. S132-S133). doi:10.1093/ecco-jcc/jjy222.217

DOI: 10.1093/ecco-jcc/jjy222.217

2018

The role of SIGLEC-1 in flavivirus infections (Conference Paper)

Prince, T. A. C., Medialdea Carrera, R., Rainbow, L., Solomon, T., Blake, N., & Griffiths, M. J. (2018). The role of SIGLEC-1 in flavivirus infections. In Encephalitis Society Conference. London.

Seasonal and Dietary Influences on Adipose Tissue and Systemic Gene Expression in Control and Previously Laminitic Ponies (Journal article)

Timpson, A. J., de Mestre, A. M., Elliott, J., Harris, P. A., Cheng, Z., Mirczuk, S. M., . . . Menzies-Gow, N. J. (2018). Seasonal and Dietary Influences on Adipose Tissue and Systemic Gene Expression in Control and Previously Laminitic Ponies. JOURNAL OF EQUINE VETERINARY SCIENCE, 69, 84-95. doi:10.1016/j.jevs.2018.06.009

DOI: 10.1016/j.jevs.2018.06.009

2017

Assessment of gene expression profiles of peripheral blood mononuclear cells from patients with a history of carbamazepine hypersensitivity (Conference Paper)

Yip, V., Zhang, E., Clarke, K., Francis, B., Rainbow, L., Falciani, F., . . . Pirmohamed, M. (2017). Assessment of gene expression profiles of peripheral blood mononuclear cells from patients with a history of carbamazepine hypersensitivity. In LANCET Vol. 389 (pp. 104). Retrieved from http://gateway.webofknowledge.com/

2016

Accurate Admission Transcriptomic Signature of the Severity of Acute Pancreatitis (Other)

Nunes, Q. M., Lane, B., Huang, W., Altaf, K., Rainbow, L., Armstrong, J., . . . Sutton, R. (2016). Accurate Admission Transcriptomic Signature of the Severity of Acute Pancreatitis. In PANCREAS (Vol. 45, Iss. 10, pp. 1530). Retrieved from http://gateway.webofknowledge.com/

2015

Identification of Potential Biomarkers of Netazepide (YF476) Treatment of Type I Gastric Neuroendocrine Tumours (Conference Paper)

Moore, A. R., Parsons, B. N., Boyce, M. J., Rainbow, L., Fang, Y., Varro, A., . . . Pritchard, D. M. (2015). Identification of Potential Biomarkers of Netazepide (YF476) Treatment of Type I Gastric Neuroendocrine Tumours. In GASTROENTEROLOGY Vol. 148 (pp. S342). Retrieved from http://gateway.webofknowledge.com/

2014

Gene Expression Profiling of Ppif(-/-) Mice in Experimental Acute Pancreatitis (Journal article)

Wen, L., Amstrong, J., Lane, B., Rainbow, L., Latawiec, D., Criddle, D. N., & Sutton, R. (2014). Gene Expression Profiling of Ppif(-/-) Mice in Experimental Acute Pancreatitis. PANCREAS, 43(8), 1421. Retrieved from http://gateway.webofknowledge.com/

Gene Expression in Blood During Increasingly Severe Cerulein-Induced Acute Pancreatitis (Journal article)

Armstrong, J., Wen, L., Rainbow, L., Latawiec, D., Lane, B., Criddle, D., & Sutton, R. (2014). Gene Expression in Blood During Increasingly Severe Cerulein-Induced Acute Pancreatitis. PANCREAS, 43(8), 1342. Retrieved from http://gateway.webofknowledge.com/

A comprehensive assessment of RNA-seq accuracy, reproducibility and information content by the Sequencing Quality Control Consortium (Journal article)

Su, Z., Labaj, P. P., Li, S., Thierry-Mieg, J., Thierry-Mieg, D., Shi, W., . . . Shi, L. (2014). A comprehensive assessment of RNA-seq accuracy, reproducibility and information content by the Sequencing Quality Control Consortium. NATURE BIOTECHNOLOGY, 32(9), 903-914. doi:10.1038/nbt.2957

DOI: 10.1038/nbt.2957

The neuroendocrine phenotype of gastric myofibroblasts and its loss with cancer progression (Journal article)

Balabanova, S., Holmberg, C., Steele, I., Ebrahimi, B., Rainbow, L., Burdyga, T., . . . Varro, A. (2014). The neuroendocrine phenotype of gastric myofibroblasts and its loss with cancer progression. Carcinogenesis, 35(8), 1798-1806. doi:10.1093/carcin/bgu086

DOI: 10.1093/carcin/bgu086

2013

Micro RNA Profiling in Acute Pancreatitis (Conference Paper)

Altaf, K., Lane, B., Rainbow, L., Halloran, C., Greenhalf, W., & Sutton, R. (2013). Micro RNA Profiling in Acute Pancreatitis. In PANCREAS Vol. 42 (pp. 1337). Retrieved from http://gateway.webofknowledge.com/

2012

Analysis of gene expression from the Wolbachia genome of a filarial nematode supports both metabolic and defensive roles within the symbiosis (Journal article)

Darby, A. C., Armstrong, S. D., Bah, G. S., Kaur, G., Hughes, M. A., Kay, S. M., . . . Makepeace, B. L. (2012). Analysis of gene expression from the Wolbachia genome of a filarial nematode supports both metabolic and defensive roles within the symbiosis. GENOME RESEARCH, 22(12), 2467-2477. doi:10.1101/gr.138420.112

DOI: 10.1101/gr.138420.112

From a Single Whole Exome Read to Notions of Clinical Screening: Primary Ciliary Dyskinesia and RSPH9 p.Lys268del in the Arabian Peninsula (Journal article)

AlSaadi, M. M., Gaunt, T. R., Boustred, C. R., Guthrie, P. A. I., Liu, X., Lenzi, L., . . . Day, I. N. M. (2012). From a Single Whole Exome Read to Notions of Clinical Screening: Primary Ciliary Dyskinesia and RSPH9 p.Lys268del in the Arabian Peninsula. ANNALS OF HUMAN GENETICS, 76, 211-220. doi:10.1111/j.1469-1809.2012.00704.x

DOI: 10.1111/j.1469-1809.2012.00704.x

2011

Gastrin stimulates expression of plasminogen activator inhibitor-1 in gastric epithelial cells (Journal article)

Norsett, K. G., Steele, I., Duval, C., Sammut, S. J., Murugesan, S. V. M., Kenny, S., . . . Varro, A. (2011). Gastrin stimulates expression of plasminogen activator inhibitor-1 in gastric epithelial cells. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 301(3), G446-G453. doi:10.1152/ajpgi.00527.2010

DOI: 10.1152/ajpgi.00527.2010

2010

Gastrin regulates the urokinase plasminogen activator system (Journal article)

Norsett, K. G., Steele, I., Rainbow, L., Murugesam, S. V. M., Duval, C., Kenny, S., . . . Varro, A. (2010). Gastrin regulates the urokinase plasminogen activator system. REGULATORY PEPTIDES, 164(1), 29. doi:10.1016/j.regpep.2010.07.067

DOI: 10.1016/j.regpep.2010.07.067

'Gastrin stimulates expression of plasminogen activator inhibitor (PAI)-1 in gastric epithelial cells' (Journal article)

Norsett, K. G., Steele, I., Duval, C., Sammut, S. J., Kenny, S., Rainbow, L., . . . Varro, A. (2010). 'Gastrin stimulates expression of plasminogen activator inhibitor (PAI)-1 in gastric epithelial cells'. American Journal of Physiology Gastrointestinal and Liver Physiology.

2004

Identification and expression of a Burkholderia pseudomallei collagenase in Escherichia coli (Journal article)

Rainbow, L., Wilkinson, M. C., Sargent, P. J., Hart, C. A., & Winstanley, C. (2004). Identification and expression of a Burkholderia pseudomallei collagenase in Escherichia coli. CURRENT MICROBIOLOGY, 48(4), 300-304. doi:10.1007/s00284-003-4192-4

DOI: 10.1007/s00284-003-4192-4

2003

Activation of mitogen-activated protein kinase and NF-kappa B pathways by a Kaposi's sarcoma-associated herpesvirus K15 membrane protein (Journal article)

Brinkmann, M. M., Glenn, M., Rainbow, L., Kieser, A., Henke-Gendo, C., & Schulz, T. F. (2003). Activation of mitogen-activated protein kinase and NF-kappa B pathways by a Kaposi's sarcoma-associated herpesvirus K15 membrane protein. JOURNAL OF VIROLOGY, 77(17), 9346-9358. doi:10.1128/JVI.77.17.9346-9358.2003

DOI: 10.1128/JVI.77.17.9346-9358.2003

Suppression-subtractive hybridisation reveals variations in gene distribution amongst the Burkholderia cepacia complex, including the presence in some strains of a genomic island containing putative polysaccharide production genes (Journal article)

Parsons, Y. N., Banasko, R., Detsika, M. G., Duangsonk, K., Rainbow, L., Hart, C. A., & Winstanley, C. (2003). Suppression-subtractive hybridisation reveals variations in gene distribution amongst the Burkholderia cepacia complex, including the presence in some strains of a genomic island containing putative polysaccharide production genes. ARCHIVES OF MICROBIOLOGY, 179(3), 214-223. doi:10.1007/s00203-003-0518-7

DOI: 10.1007/s00203-003-0518-7

2002

Distribution of type III secretion gene clusters in Burkholderia pseudomallei, B-thailandensis and B-mallei (Journal article)

Rainbow, L., Hart, C. A., & Winstanley, C. (2002). Distribution of type III secretion gene clusters in Burkholderia pseudomallei, B-thailandensis and B-mallei. JOURNAL OF MEDICAL MICROBIOLOGY, 51(5), 374-384. doi:10.1099/0022-1317-51-5-374

DOI: 10.1099/0022-1317-51-5-374

1999

Identification of a spliced gene from Kaposi's sarcoma-associated herpesvirus encoding a protein with similarities to latent membrane proteins 1 and 2A of Epstein-Barr virus (Journal article)

Glenn, M., Rainbow, L., Aurade, F., Davison, A., & Schulz, T. F. (1999). Identification of a spliced gene from Kaposi's sarcoma-associated herpesvirus encoding a protein with similarities to latent membrane proteins 1 and 2A of Epstein-Barr virus. JOURNAL OF VIROLOGY, 73(8), 6953-6963. doi:10.1128/JVI.73.8.6953-6963.1999

DOI: 10.1128/JVI.73.8.6953-6963.1999

1997

The 222- to 234-kilodalton latent nuclear protein (LNA) of Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) is encoded by orf73 and is a component of the latency-associated nuclear antigen (Journal article)

Rainbow, L., Platt, G. M., Simpson, G. R., Sarid, R., Gao, S. J., Stoiber, H., . . . Schulz, T. F. (1997). The 222- to 234-kilodalton latent nuclear protein (LNA) of Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) is encoded by orf73 and is a component of the latency-associated nuclear antigen. JOURNAL OF VIROLOGY, 71(8), 5915-5921. doi:10.1128/JVI.71.8.5915-5921.1997

DOI: 10.1128/JVI.71.8.5915-5921.1997

1996

Prevalence of Kaposi's sarcoma associated herpesvirus infection measured by antibodies to recombinant capsid protein and latent immunofluorescence antigen (Journal article)

Simpson, G. R., Schulz, T. F., Whitby, D., Cook, P. M., Boshoff, C., Rainbow, L., . . . Moore, P. S. (1996). Prevalence of Kaposi's sarcoma associated herpesvirus infection measured by antibodies to recombinant capsid protein and latent immunofluorescence antigen. LANCET, 348(9035), 1133-1138. doi:10.1016/S0140-6736(96)07560-5

DOI: 10.1016/S0140-6736(96)07560-5

1994

ULTRASTRUCTURAL-CHANGES IN MURINE LYMPHOCYTES INDUCED BY AFLATOXIN-B1 (Journal article)

RAINBOW, L., MAXWELL, S. M., & HENDRICKSE, R. G. (1994). ULTRASTRUCTURAL-CHANGES IN MURINE LYMPHOCYTES INDUCED BY AFLATOXIN-B1. MYCOPATHOLOGIA, 125(1), 33-39. doi:10.1007/BF01103973

DOI: 10.1007/BF01103973