Genomics at the Institute

Scientists working within genomics at the Institute are engaged in pioneering research projects across areas as diverse as food security, cancer research and new molecules discovery.

Supported by the Centre for Genomic Research (CGR), genomics research in Liverpool is driven by a desire to understand the genetic make-up of organisms and the environments in which they live. With multiplatform sequencing and array technologies, complimented by a team of technologists and informaticians, our scientists are engaged in research spanning areas such as human and veterinary medicine, biotechnology, environmental and evolutionary biology, agri-tech and zoology.

Our scientists

To find out more about the research interests and work of our team, please see the profiles of our experts:

Case study: Industrial melanism

A textbook example of evolution that supported Darwin's theory and rapid adaptation is the spread of a melanic (black) mutant of the Peppered moth, following the industrial revolution, that matched the soot-darkened trees. Following the Clean Air Acts of 1956 and '68, the lighter form returned. The CGR supported a landmark study by Saccheri that found the gene responsible and examined its spread in historical samples. This work resulted in a Nature paper and widespread coverage in the press.

'Dark satanic wings' (Nature, June 2016)

'Famous peppered moth's dark secret revealed' (BBC News, June 2016)

Case study: African Salmonella

Invasive nontyphoidal Salmonella kills nearly 400,000 people in sub-Saharan Africa every year. The University of Liverpool, with colleagues in Malawi and the Liverpool School of Tropical Medicine, is leading the fight against this important pathogen. The CGR supported work from Hinton to characterise the pathogen's genome and understand how it regulates the expression of its genes to allow it to infect and survive within a host.

Gene expression study sheds new light on African Salmonella

Adding function to the genome of African Salmonella

Centre for Genomic Research

Watch Professor Steve Paterson, CGR Director, introduce the CGR facility.

Genomics has revolutionised all areas of biology, from antimicrobial resistance to climate change. Genomics can help us answer difficult questions and contribute to outstanding, world-class research

Professor Steve Paterson

Join our team

We are currently expanding our genomics team and are looking for people with expertise in functional and single-cell genomics, omics systems and data integration, infection and microbiome genomics and evolutionary and ecological genomics.

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