Host Microbe Interactions

Dynamics and Management of Host Microbe Interactions

Prevention of infection requires us to understand how individuals come into contact with each other and microbes, and determining which individuals are most vulnerable to infection.

We study these interactions across many scales, from the molecular interplay between microbe and host, through to modelling the changes in parasite frequency in populations.

Our researchers examine medical, agricultural, and wildlife systems on the basis that fundamental advances in one system can lead to applied benefits in another.

Areas of research

  • Determining microbial factors that determine the progression of infection.
  • Evaluating why infection outcome varies between individuals, with particular reference to the impact of individual condition and history of infection.
  • Understanding the development of the microbiome in a healthy host, and understanding the importance of symbiotic microbes for host function.
  • Combining the above to understand the dynamics of pathogens/parasites in natural populations, and their influence on host ecology and evolution.
Microbes news - salmonella

Genome scientists use UK Salmonella cases to shed light on African epidemic

Scientists at the University of Liverpool and Public Health England have used Salmonella genome data from a UK public health surveillance study to gain new insights into the Salmonella epidemic in sub-Saharan Africa. Read more...

Microbes news - vole

Study reveals that individuals have immune 'personalities'

Researchers from the University's Institute of Integrative Biology, working with external collaborators have identified consistent individual differences in immunity, or what they call ‘immune personalities’, in a wild population of rodents. Read more...

Microbes news - Kate Baker

Using genome sequencing to understand the spread of disease and antimicrobial resistance

Kate Baker joined the Institute at the end of 2016, from the Sanger Institute, a non-profit genomics and genetics research institute, based outside Cambridge. Read more...