Photo of Dr Georgios Pollakis

Dr Georgios Pollakis PhD

Senior research Fellow Clinical Infection, Microbiology and Immunology

    Publications

    Selected Publications

    1. Blood CXCR3(+) CD4 T Cells Are Enriched in Inducible Replication Competent HIV in Aviremic Antiretroviral Therapy-Treated Individuals (Journal article - 2018)
    2. CD25(+) FoxP3(+) Memory CD4 T Cells Are Frequent Targets of HIV Infection In Vivo (Journal article - 2016)
    3. Temporal and spatial analysis of the 2014-2015 Ebola virus outbreak in West Africa (Journal article - 2015)
    4. Characterisation of Transmitted and Non-transmitted HIV in Index-recipient Transmission Pairs (Conference Paper - 2014)
    5. Envelope-Specific Recognition Patterns of HIV Vaccine-Induced IgG Antibodies Are Linked to Immunogen Structure and Sequence (Journal article - 2019)

    2019

    Bile-salt stimulated lipase polymorphisms do not associate with HCV susceptibility (Journal article)

    Steba, G. S., Koekkoek, S. M., Prins, M., Brinkman, K., Kwa, D., van der Meer, J. T. M., . . . Acu, M. O. S. A. I. C. M. S. M. O. S. (2019). Bile-salt stimulated lipase polymorphisms do not associate with HCV susceptibility. VIRUS RESEARCH, 274. doi:10.1016/j.virusres.2019.197715

    DOI: 10.1016/j.virusres.2019.197715

    High Resolution Analysis of Respiratory Syncytial Virus Infection In Vivo (Journal article)

    Aljabr, W., Armstrong, S., Rickett, N. Y., Pollakis, G., Touzelet, O., Cloutman-Green, E., . . . Hiscox, J. A. (2019). High Resolution Analysis of Respiratory Syncytial Virus Infection In Vivo. VIRUSES-BASEL, 11(10). doi:10.3390/v11100926

    DOI: 10.3390/v11100926

    Schistosoma mansoni soluble egg antigen (SEA) and recombinant Omega-1 modulate induced CD4(+) T-lymphocyte responses and HIV-1 infection in vitro (Journal article)

    Mouser, E. E. I. M., Pollakis, G., Smits, H. H., Thomas, J., Yazdanbakhsh, M., de Jong, E. C., & Paxton, W. A. (2019). Schistosoma mansoni soluble egg antigen (SEA) and recombinant Omega-1 modulate induced CD4(+) T-lymphocyte responses and HIV-1 infection in vitro. PLOS PATHOGENS, 15(9). doi:10.1371/journal.ppat.1007924

    DOI: 10.1371/journal.ppat.1007924

    Envelope-Specific Recognition Patterns of HIV Vaccine-Induced IgG Antibodies Are Linked to Immunogen Structure and Sequence (Journal article)

    Nadai, Y., Held, K., Joseph, S., Ahmed, M. I. M., Hoffmann, V. S., Peterhoff, D., . . . Geldmacher, C. (2019). Envelope-Specific Recognition Patterns of HIV Vaccine-Induced IgG Antibodies Are Linked to Immunogen Structure and Sequence. FRONTIERS IN IMMUNOLOGY, 10. doi:10.3389/fimmu.2019.00717

    DOI: 10.3389/fimmu.2019.00717

    Dendritic Cells Potently Purge Latent HIV-1 in TCR-Activated Cells via the PI3K-Akt-mTOR Pathway: Implications for ‘Shock and Kill’ Strategies and Reservoir Analysis (Journal article)

    van Montfort, T., van der Sluis, R., Darcis, G., Beaty, D., Groen, K., Pasternak, A. O., . . . Berkhout, B. (2019). Dendritic Cells Potently Purge Latent HIV-1 in TCR-Activated Cells via the PI3K-Akt-mTOR Pathway: Implications for ‘Shock and Kill’ Strategies and Reservoir Analysis. EBioMedicine.

    Dendritic cells potently purge latent HIV-1 beyond TCR-stimulation, activating the PI3K-Akt-mTOR pathway (Journal article)

    van Montfort, T., van der Sluis, R., Darcis, G., Beaty, D., Groen, K., Pasternak, A. O., . . . Berkhout, B. (2019). Dendritic cells potently purge latent HIV-1 beyond TCR-stimulation, activating the PI3K-Akt-mTOR pathway. EBioMedicine. doi:10.1016/j.ebiom.2019.02.014

    DOI: 10.1016/j.ebiom.2019.02.014

    2018

    Comparative analysis and generation of a robust HIV-1 DNA quantification assay (Journal article)

    Thomas, J., Ruggiero, A., Procopio, F. A., Pantaleo, G., Paxton, W. A., & Pollakis, G. (2019). Comparative analysis and generation of a robust HIV-1 DNA quantification assay. JOURNAL OF VIROLOGICAL METHODS, 263, 24-31. doi:10.1016/j.jviromet.2018.10.010

    DOI: 10.1016/j.jviromet.2018.10.010

    Development of a Sensitive qPCR Assay for Quantification of Integrated HIV-1 DNA in Peripheral Blood Mononuclear Cells (Journal article)

    Ruggiero, A., Malatinkova, E., De Spiegelaere, W., Thomas, J., Rutsaert, S., Geretti, A. M., . . . Paxton, W. A. (n.d.). Development of a Sensitive qPCR Assay for Quantification of Integrated HIV-1 DNA in Peripheral Blood Mononuclear Cells. Journal of Virological Methods.

    SNP rs688 within the low-density lipoprotein receptor (LDL-R) gene associates with HCV susceptibility. (Journal article)

    Steba, G. S., Koekkoek, S. M., Tanck, M. W. T., Vanhommerig, J. W., van der Meer, J. T. M., Kwa, D., . . . MOSAIC (MSM observational Study of Acute infection with Hepatitis C) Study Group and the ACS (Amsterdam Cohort Studies). (2018). SNP rs688 within the low-density lipoprotein receptor (LDL-R) gene associates with HCV susceptibility.. Liver international : official journal of the International Association for the Study of the Liver. doi:10.1111/liv.13978

    DOI: 10.1111/liv.13978

    Blood CXCR3(+) CD4 T Cells Are Enriched in Inducible Replication Competent HIV in Aviremic Antiretroviral Therapy-Treated Individuals (Journal article)

    Banga, R., Procopio, F. A., Ruggiero, A., Noto, A., Ohmiti, K., Cavassini, M., . . . Perreau, M. (2018). Blood CXCR3(+) CD4 T Cells Are Enriched in Inducible Replication Competent HIV in Aviremic Antiretroviral Therapy-Treated Individuals. FRONTIERS IN IMMUNOLOGY, 9. doi:10.3389/fimmu.2018.00144

    DOI: 10.3389/fimmu.2018.00144

    Detection, characterization, and enrollment of donors of Ebola convalescent plasma in Sierra Leone (Journal article)

    Tedder, R. S., Samuel, D., Dicks, S., Scott, J. T., Ijaz, S., Smith, C. C., . . . Investigators, E. C. P. C. (2018). Detection, characterization, and enrollment of donors of Ebola convalescent plasma in Sierra Leone. TRANSFUSION, 58(5), 1289-1298. doi:10.1111/trf.14580

    DOI: 10.1111/trf.14580

    2017

    Virus genomes reveal factors that spread and sustained the Ebola epidemic (Journal article)

    Dudas, G., Carvalho, L. M., Bedford, T., Tatem, A. J., Baele, G., Faria, N. R., . . . Rambaut, A. (2017). Virus genomes reveal factors that spread and sustained the Ebola epidemic. NATURE, 544(7650), 309-+. doi:10.1038/nature22040

    DOI: 10.1038/nature22040

    2016

    CD25(+) FoxP3(+) Memory CD4 T Cells Are Frequent Targets of HIV Infection In Vivo (Journal article)

    Chachage, M., Pollakis, G., Kuffour, E. O., Haase, K., Bauer, A., Nadai, Y., . . . Geldmacher, C. (2016). CD25(+) FoxP3(+) Memory CD4 T Cells Are Frequent Targets of HIV Infection In Vivo. JOURNAL OF VIROLOGY, 90(20), 8954-8967. doi:10.1128/JVI.00612-16

    DOI: 10.1128/JVI.00612-16

    Env-specific IgG Responses Induced by Identical and None-identical Immunogen Prime-boost Vaccination Strategies Target Different Antigenic Regions (Conference Paper)

    Nadai, Y., Ahmed, M. I. M., Joseph, S., Missanga, M., Bauer, A., Cope, A. V., . . . Held, K. (2016). Env-specific IgG Responses Induced by Identical and None-identical Immunogen Prime-boost Vaccination Strategies Target Different Antigenic Regions. In AIDS RESEARCH AND HUMAN RETROVIRUSES Vol. 32 (pp. 392). Retrieved from http://gateway.webofknowledge.com/

    PD-1(+) and follicular helper T cells are responsible for persistent HIV-1 transcription in treated aviremic individuals (Journal article)

    Banga, R., Procopio, F. A., Noto, A., Pollakis, G., Cavassini, M., Ohmiti, K., . . . Perreau, M. (2016). PD-1(+) and follicular helper T cells are responsible for persistent HIV-1 transcription in treated aviremic individuals. NATURE MEDICINE, 22(7), 754-761. doi:10.1038/nm.4113

    DOI: 10.1038/nm.4113

    Real-time, portable genome sequencing for Ebola surveillance (Journal article)

    Quick, J., Loman, N. J., Duraffour, S., Simpson, J. T., Severi, E., Cowley, L., . . . Carroll, M. W. (2016). Real-time, portable genome sequencing for Ebola surveillance. NATURE, 530(7589), 228-+. doi:10.1038/nature16996

    DOI: 10.1038/nature16996

    Brugia malayi Antigen (BmA) Inhibits HIV-1 Trans-Infection but Neither BmA nor ES-62 Alter HIV-1 Infectivity of DC Induced CD4(+) Th-Cells (Journal article)

    Mouser, E. E. I. M., Pollakis, G., Yazdanbakhsh, M., Harnett, W., de Jong, E. C., & Paxton, W. A. (2016). Brugia malayi Antigen (BmA) Inhibits HIV-1 Trans-Infection but Neither BmA nor ES-62 Alter HIV-1 Infectivity of DC Induced CD4(+) Th-Cells. PLOS ONE, 11(1). doi:10.1371/journal.pone.0146527

    DOI: 10.1371/journal.pone.0146527

    2015

    Investigating the Influence of Ribavirin on Human Respiratory Syncytial Virus RNA Synthesis by Using a High-Resolution Transcriptome Sequencing Approach (Journal article)

    Aljabr, W., Touzelet, O., Pollakis, G., Wu, W., Munday, D. C., Hughes, M., . . . Hiscox, J. A. (2016). Investigating the Influence of Ribavirin on Human Respiratory Syncytial Virus RNA Synthesis by Using a High-Resolution Transcriptome Sequencing Approach. JOURNAL OF VIROLOGY, 90(10), 4876-4888. doi:10.1128/JVI.02349-15

    DOI: 10.1128/JVI.02349-15

    During Stably Suppressive Antiretroviral Therapy Integrated HIV-1 DNA Load in Peripheral Blood is Associated with the Frequency of CD8 Cells Expressing HLA-DR/DP/DQ (Journal article)

    Ruggiero, A., De Spiegelaere, W., Cozzi-Lepri, A., Kiselinova, M., Pollakis, G., Beloukas, A., . . . Grp, E. R. A. S. S. (2015). During Stably Suppressive Antiretroviral Therapy Integrated HIV-1 DNA Load in Peripheral Blood is Associated with the Frequency of CD8 Cells Expressing HLA-DR/DP/DQ. EBIOMEDICINE, 2(9), 1153-1159. doi:10.1016/j.ebiom.2015.07.025

    DOI: 10.1016/j.ebiom.2015.07.025

    Association between gp120 envelope V1V2 and V4V5 variable loop profiles in a defined HIV-1 transmission cluster (Journal article)

    Pollakis, G., Baan, E., van Werkhoven, M. B., Berkhout, B., Bakker, M., Jurriaans, S., & Paxton, W. A. (2015). Association between gp120 envelope V1V2 and V4V5 variable loop profiles in a defined HIV-1 transmission cluster. AIDS, 29(10), 1161-1171. doi:10.1097/QAD.0000000000000692

    DOI: 10.1097/QAD.0000000000000692

    The burden of integrated HIV-1 DNA during suppressive ART is associated with levels of activated (HLA-DR+) CD8 T cells (Journal article)

    Ruggiero, A., King, S., Pollakis, G., Beloukas, A., Geretti, A. M., Vandekerckhove, L., . . . Phillips, A. (2015). The burden of integrated HIV-1 DNA during suppressive ART is associated with levels of activated (HLA-DR+) CD8 T cells. HIV MEDICINE, 16, 21. Retrieved from http://gateway.webofknowledge.com/

    Colorectal Mucus Binds DC-SIGN and Inhibits HIV-1 Trans-Infection of CD4(+) T-Lymphocytes (Journal article)

    Stax, M. J., Mouser, E. E. I. M., van Montfort, T., Sanders, R. W., de Vries, H. J. C., Dekker, H. L., . . . Paxton, W. A. (2015). Colorectal Mucus Binds DC-SIGN and Inhibits HIV-1 Trans-Infection of CD4(+) T-Lymphocytes. PLOS ONE, 10(3). doi:10.1371/journal.pone.0122020

    DOI: 10.1371/journal.pone.0122020

    Improved metastasis-free survival in nonadjuvantly treated postmenopausal breast cancer patients with chemokine receptor 5 del32 frameshift mutations (Journal article)

    Span, P. N., Pollakis, G., Paxton, W. A., Sweep, F. C. G. J., Foekens, J. A., Martens, J. W. M., . . . van Laarhoven, H. W. M. (2015). Improved metastasis-free survival in nonadjuvantly treated postmenopausal breast cancer patients with chemokine receptor 5 del32 frameshift mutations. INTERNATIONAL JOURNAL OF CANCER, 136(1), 91-97. doi:10.1002/ijc.28962

    DOI: 10.1002/ijc.28962

    Temporal and spatial analysis of the 2014-2015 Ebola virus outbreak in West Africa (Journal article)

    Carroll, M. W., Matthews, D. A., Hiscox, J. A., Elmore, M. J., Pollakis, G., Rambaut, A., . . . Guenther, S. (2015). Temporal and spatial analysis of the 2014-2015 Ebola virus outbreak in West Africa. NATURE, 524(7563), 97-U201. doi:10.1038/nature14594

    DOI: 10.1038/nature14594

    2014

    Characterisation of Transmitted and Non-transmitted HIV in Index-recipient Transmission Pairs (Conference Paper)

    Bracke, L., Willems, E., Gall, A., Kellam, P., Coppens, S., Meehan, C., . . . Arien, K. (2014). Characterisation of Transmitted and Non-transmitted HIV in Index-recipient Transmission Pairs. In AIDS RESEARCH AND HUMAN RETROVIRUSES Vol. 30 (pp. A224-A225). Retrieved from http://gateway.webofknowledge.com/

    Increased HIV-1 Activity in Anal High-Grade Squamous Intraepithelial Lesions Compared With Unaffected Anal Mucosa in Men Who Have Sex With Men (Journal article)

    Pollakis, G., Richel, O., Vis, J. D., Prins, J. M., Paxton, W. A., & de Vries, H. J. C. (2014). Increased HIV-1 Activity in Anal High-Grade Squamous Intraepithelial Lesions Compared With Unaffected Anal Mucosa in Men Who Have Sex With Men. CLINICAL INFECTIOUS DISEASES, 58(11), 1634-1637. doi:10.1093/cid/ciu133

    DOI: 10.1093/cid/ciu133

    2013

    HIV-1 Autologous Antibody Neutralization Associates with Mother to Child Transmission (Journal article)

    Baan, E., de Ronde, A., Stax, M., Sanders, R. W., Luchters, S., Vyankandondera, J., . . . Paxton, W. A. (2013). HIV-1 Autologous Antibody Neutralization Associates with Mother to Child Transmission. PLOS ONE, 8(7). doi:10.1371/journal.pone.0069274

    DOI: 10.1371/journal.pone.0069274

    Dendritic Cell-induced Activation of Latent HIV-1 Provirus in Actively Proliferating Primary T Lymphocytes (Journal article)

    van der Sluis, R. M., van Montfort, T., Pollakis, G., Sanders, R. W., Speijer, D., Berkhout, B., & Jeeninga, R. E. (2013). Dendritic Cell-induced Activation of Latent HIV-1 Provirus in Actively Proliferating Primary T Lymphocytes. PLOS PATHOGENS, 9(3). doi:10.1371/journal.ppat.1003259

    DOI: 10.1371/journal.ppat.1003259

    Human immunodeficiency virus type 1 gp120 envelope characteristics associated with disease progression differ in family members infected with genetically similar viruses (Journal article)

    Baan, E., van der Sluis, R. M., Bakker, M. E., Bekker, V., Pajkrt, D., Jurriaans, S., . . . Pollakis, G. (2013). Human immunodeficiency virus type 1 gp120 envelope characteristics associated with disease progression differ in family members infected with genetically similar viruses. JOURNAL OF GENERAL VIROLOGY, 94, 20-29. doi:10.1099/vir.0.046185-0

    DOI: 10.1099/vir.0.046185-0

    Quantitation of HIV-1 DNA with a sensitive TaqMan assay that has broad subtype specificity (Journal article)

    van der Sluis, R. M., van Montfort, T., Centlivre, M., Schopman, N. C. T., Cornelissen, M., Sanders, R. W., . . . Pollakis, G. (2013). Quantitation of HIV-1 DNA with a sensitive TaqMan assay that has broad subtype specificity. JOURNAL OF VIROLOGICAL METHODS, 187(1), 94-102. doi:10.1016/j.jviromet.2012.09.019

    DOI: 10.1016/j.jviromet.2012.09.019

    2012

    Selective packaging of cellular miRNAs in HIV-1 particles (Journal article)

    Schopman, N. C. T., van Montfort, T., Willemsen, M., Knoepfel, S. A., Pollakis, G., van Kampen, A., . . . Berkhout, B. (2012). Selective packaging of cellular miRNAs in HIV-1 particles. VIRUS RESEARCH, 169(2), 438-447. doi:10.1016/j.virusres.2012.06.017

    DOI: 10.1016/j.virusres.2012.06.017

    Use of (alternative) coreceptors for HIV entry (Journal article)

    Pollakis, G., & Paxton, W. A. (2012). Use of (alternative) coreceptors for HIV entry. CURRENT OPINION IN HIV AND AIDS, 7(5), 440-449. doi:10.1097/COH.0b013e328356e9f3

    DOI: 10.1097/COH.0b013e328356e9f3

    HIV Type 1 Mother-to-Child Transmission Facilitated by Distinctive Glycosylation Sites in the gp120 Envelope Glycoprotein (Journal article)

    Baan, E., de Ronde, A., Luchters, S., Vyankandondera, J., Lange, J. M., Pollakis, G., & Paxton, W. A. (2012). HIV Type 1 Mother-to-Child Transmission Facilitated by Distinctive Glycosylation Sites in the gp120 Envelope Glycoprotein. AIDS RESEARCH AND HUMAN RETROVIRUSES, 28(7), 715-724. doi:10.1089/aid.2011.0023

    DOI: 10.1089/aid.2011.0023

    Effects of helminths and Mycobacterium tuberculosis infection on HIV-1: a cellular immunological perspective (Journal article)

    Mouser, E. E. I. M., Pollakis, G., & Paxton, W. A. (2012). Effects of helminths and Mycobacterium tuberculosis infection on HIV-1: a cellular immunological perspective. CURRENT OPINION IN HIV AND AIDS, 7(3), 260-267. doi:10.1097/COH.0b013e3283521144

    DOI: 10.1097/COH.0b013e3283521144

    HIV-1 Disease Progression Is Associated with Bile-Salt Stimulated Lipase (BSSL) Gene Polymorphism (Journal article)

    Stax, M. J., Kootstra, N. A., van 't Wout, A. B., Tanck, M. W. T., Bakker, M., Pollakis, G., & Paxton, W. A. (2012). HIV-1 Disease Progression Is Associated with Bile-Salt Stimulated Lipase (BSSL) Gene Polymorphism. PLOS ONE, 7(3). doi:10.1371/journal.pone.0032534

    DOI: 10.1371/journal.pone.0032534

    Transmission of Two Distinct HIV Type 1 Strains to an Individual That Were Harbored for Many Years by Another (Journal article)

    van Werkhoven, M. B., Baan, E., Bakker, M., Jurriaans, S., Paxton, W. A., & Pollakis, G. (2012). Transmission of Two Distinct HIV Type 1 Strains to an Individual That Were Harbored for Many Years by Another. AIDS RESEARCH AND HUMAN RETROVIRUSES, 28(2), 225-227. doi:10.1089/aid.2011.0178

    DOI: 10.1089/aid.2011.0178

    2011

    Latency profiles of full length HIV-1 molecular clone variants with a subtype specific promoter (Journal article)

    van der Sluis, R. M., Pollakis, G., van Gerven, M. L., Berkhout, B., & Jeeninga, R. E. (2011). Latency profiles of full length HIV-1 molecular clone variants with a subtype specific promoter. RETROVIROLOGY, 8. doi:10.1186/1742-4690-8-73

    DOI: 10.1186/1742-4690-8-73

    Innate immune factors associated with HIV-1 transmission (Journal article)

    Pollakis, G., Stax, M. J., & Paxton, W. A. (2011). Innate immune factors associated with HIV-1 transmission. CURRENT OPINION IN HIV AND AIDS, 6(5), 341-347. doi:10.1097/COH.0b013e3283499e11

    DOI: 10.1097/COH.0b013e3283499e11

    Altered dynamics and differential infection profiles of lymphoid and myeloid cell subsets during acute and chronic HIV-1 infection (Journal article)

    Centlivre, M., Legrand, N., Steingrover, R., van der Sluis, R., Grijsen, M. L., Bakker, M., . . . Pollakis, G. (2011). Altered dynamics and differential infection profiles of lymphoid and myeloid cell subsets during acute and chronic HIV-1 infection. JOURNAL OF LEUKOCYTE BIOLOGY, 89(5), 785-795. doi:10.1189/jlb.0410231

    DOI: 10.1189/jlb.0410231

    Binding of Human Milk to Pathogen Receptor DC-SIGN Varies with Bile Salt-Stimulated Lipase (BSSL) Gene Polymorphism (Journal article)

    Stax, M. J., Naarding, M. A., Tanck, M. W. T., Lindquist, S., Hernell, O., Lyle, R., . . . Paxton, W. A. (2011). Binding of Human Milk to Pathogen Receptor DC-SIGN Varies with Bile Salt-Stimulated Lipase (BSSL) Gene Polymorphism. PLOS ONE, 6(2). doi:10.1371/journal.pone.0017316

    DOI: 10.1371/journal.pone.0017316

    HIV-1 disease progression is associated with bile-salt stimulated lipase (BSSL) gene polymorphism. (Journal article)

    Stax, M. J., Kootstra, N. A., van't Wout, A. B., Bakker, M., Pollakis, G., & Paxton, W. A. (2011). HIV-1 disease progression is associated with bile-salt stimulated lipase (BSSL) gene polymorphism.. Retrovirology, 8(Suppl 2), P65. doi:10.1186/1742-4690-8-S2-P65

    DOI: 10.1186/1742-4690-8-S2-P65

    2010

    Preferential infection and depletion of Mycobacterium tuberculosis-specific CD4 T cells after HIV-1 infection (Journal article)

    Geldmacher, C., Ngwenyama, N., Schuetz, A., Petrovas, C., Reither, K., Heeregrave, E. J., . . . Koup, R. A. (2010). Preferential infection and depletion of Mycobacterium tuberculosis-specific CD4 T cells after HIV-1 infection. JOURNAL OF EXPERIMENTAL MEDICINE, 207(13), 2869-2881. doi:10.1084/jem.20100090

    DOI: 10.1084/jem.20100090

    Generation of representative primary virus isolates from blood plasma after isolation of HIV-1 with CD44 MicroBeads (Journal article)

    Cornelissen, M., Heeregrave, E. J., Zorgdrager, F., Pollakis, G., Paxton, W. A., & van der Kuyl, A. C. (2010). Generation of representative primary virus isolates from blood plasma after isolation of HIV-1 with CD44 MicroBeads. ARCHIVES OF VIROLOGY, 155(12), 2017-2022. doi:10.1007/s00705-010-0806-x

    DOI: 10.1007/s00705-010-0806-x

    Differences in HIV Type 1 RNA Plasma Load Profile of Closely Related Cocirculating Ethiopian Subtype C Strains: C and C ' (Journal article)

    Ayele, W., Mekonnen, Y., Messele, T., Mengistu, Y., Tsegaye, A., Bakker, M., . . . Pollakis, G. (2010). Differences in HIV Type 1 RNA Plasma Load Profile of Closely Related Cocirculating Ethiopian Subtype C Strains: C and C '. AIDS RESEARCH AND HUMAN RETROVIRUSES, 26(7), 805-813. doi:10.1089/aid.2009.0152

    DOI: 10.1089/aid.2009.0152

    HIV RNA levels in transmission sources only weakly predict plasma viral load in recipients (Journal article)

    van der Kuyl, A. C., Jurriaans, S., Pollakis, G., Bakker, M., & Cornelissen, M. (2010). HIV RNA levels in transmission sources only weakly predict plasma viral load in recipients. AIDS, 24(10), 1607-1608. doi:10.1097/QAD.0b013e32833b318f

    DOI: 10.1097/QAD.0b013e32833b318f

    HIV-1 (co)Receptors: Implications for Vaccine and Therapy Design (Journal article)

    Pollakis, G., & Paxton, W. A. (2010). HIV-1 (co)Receptors: Implications for Vaccine and Therapy Design. CURRENT PHARMACEUTICAL DESIGN, 16(33), 3701-3715. doi:10.2174/138161210794079146

    DOI: 10.2174/138161210794079146

    Varied sensitivity to therapy of HIV-1 strains in CD4(+) lymphocyte sub-populations upon ART initiation (Journal article)

    Heeregrave, E. J., Geels, M. J., Baan, E., van der Sluis, R. M., Paxton, W. A., & Pollakis, G. (2010). Varied sensitivity to therapy of HIV-1 strains in CD4(+) lymphocyte sub-populations upon ART initiation. AIDS RESEARCH AND THERAPY, 7. doi:10.1186/1742-6405-7-42

    DOI: 10.1186/1742-6405-7-42

    2009

    Lack of in vivo compartmentalization among HIV-1 infected naive and memory CD4(+) T cell subsets (Journal article)

    Heeregrave, E. J., Geels, M. J., Brenchley, J. M., Laan, E., Ambrozak, D. R., van der Sluis, R. M., . . . Paxton, W. A. (2009). Lack of in vivo compartmentalization among HIV-1 infected naive and memory CD4(+) T cell subsets. VIROLOGY, 393(1), 24-32. doi:10.1016/j.virol.2009.07.011

    DOI: 10.1016/j.virol.2009.07.011

    Mucin 6 in seminal plasma binds DC-SIGN and potently blocks dendritic cell mediated transfer of HIV-1 to CD4(+) T-lymphocytes (Journal article)

    Stax, M. J., van Montfort, T., Sprenger, R. R., Melchers, M., Sanders, R. W., van Leeuwen, E., . . . Paxton, W. A. (2009). Mucin 6 in seminal plasma binds DC-SIGN and potently blocks dendritic cell mediated transfer of HIV-1 to CD4(+) T-lymphocytes. VIROLOGY, 391(2), 203-211. doi:10.1016/j.virol.2009.06.011

    DOI: 10.1016/j.virol.2009.06.011

    RNA detection and subtype C assessment of HIV-1 in infants with diarrhea in Ethiopia. (Journal article)

    Ayele, W., Assefa, T., Lulseged, S., Tegbaru, B., Berhanu, H., Tamene, W., . . . Pollakis, G. (2009). RNA detection and subtype C assessment of HIV-1 in infants with diarrhea in Ethiopia.. The open AIDS journal, 3, 19-23. doi:10.2174/1874613600903010019

    DOI: 10.2174/1874613600903010019

    Natural compounds in bodily fluids which bind DC-SIGN and prevent HIV-1 capture and transfer to CD4 cells (Conference Paper)

    Stax, M. J., Pollakis, G., Sprenger, R. R., Melchers, M., van Montfort, T., Sanders, R. W., . . . Paxton, W. A. (2009). Natural compounds in bodily fluids which bind DC-SIGN and prevent HIV-1 capture and transfer to CD4 cells. In RETROVIROLOGY Vol. 6. doi:10.1186/1742-4690-6-S3-P108

    DOI: 10.1186/1742-4690-6-S3-P108

    Optimization of Human Immunodeficiency Virus Type 1 Envelope Glycoproteins with V1/V2 Deleted, Using Virus Evolution (Journal article)

    Bontjer, I., Land, A., Eggink, D., Verkade, E., Tuin, K., Baldwin, C., . . . Sanders, R. W. (2009). Optimization of Human Immunodeficiency Virus Type 1 Envelope Glycoproteins with V1/V2 Deleted, Using Virus Evolution. JOURNAL OF VIROLOGY, 83(1), 368-383. doi:10.1128/JVI.01404-08

    DOI: 10.1128/JVI.01404-08

    2008

    Dendritic cells preferentially transfer CXCR4-using human immunodeficiency virus type 1 variants to CD4(+) T lymphocytes in trans (Journal article)

    van Montfort, T., Thomas, A. A. M., Pollakis, G., & Paxton, W. A. (2008). Dendritic cells preferentially transfer CXCR4-using human immunodeficiency virus type 1 variants to CD4(+) T lymphocytes in trans. JOURNAL OF VIROLOGY, 82(16), 7886-7896. doi:10.1128/JVI.00245-08

    DOI: 10.1128/JVI.00245-08

    2007

    Statins Disrupt CCR5 and RANTES Expression Levels in CD4(+) T Lymphocytes In Vitro and Preferentially Decrease Infection of R5 Versus X4 HIV-1 (Journal article)

    Nabatov, A. A., Pollakis, G., Linnemann, T., Paxton, W. A., & de Baar, M. P. (2007). Statins Disrupt CCR5 and RANTES Expression Levels in CD4(+) T Lymphocytes In Vitro and Preferentially Decrease Infection of R5 Versus X4 HIV-1. PLOS ONE, 2(5). doi:10.1371/journal.pone.0000470

    DOI: 10.1371/journal.pone.0000470

    Characterization of an HIV-1 group m variant that is distinct from the known subtypes (Journal article)

    Van der Hoek, L., Pollakis, G., Lukashov, V. V., Jebbink, M. F., Jeeninga, R. E., Bakker, M., . . . Berkhout, B. (2007). Characterization of an HIV-1 group m variant that is distinct from the known subtypes. AIDS RESEARCH AND HUMAN RETROVIRUSES, 23(3), 466-470. doi:10.1089/aid.2006.0184

    DOI: 10.1089/aid.2006.0184

    Efficient capture of antibody neutralized HIV-1 by cells expressing DC-SIGN and transfer to CD4(+) T lymphocytes (Journal article)

    van Montfort, T., Nabatov, A. A., Geijtenbeek, T. B. H., Pollakis, G., & Paxton, W. A. (2007). Efficient capture of antibody neutralized HIV-1 by cells expressing DC-SIGN and transfer to CD4(+) T lymphocytes. JOURNAL OF IMMUNOLOGY, 178(5), 3177-3185. doi:10.4049/jimmunol.178.5.3177

    DOI: 10.4049/jimmunol.178.5.3177

    Use of dried spots of whole blood, plasma, and mother's milk collected on filter paper for measurement of human immunodeficiency virus type 1 burden (Journal article)

    Ayele, W., Schuurman, R., Messele, T., Dorigo-Zetsma, W., Mengistu, Y., Goudsmit, J., . . . Pollakis, G. (2007). Use of dried spots of whole blood, plasma, and mother's milk collected on filter paper for measurement of human immunodeficiency virus type 1 burden. JOURNAL OF CLINICAL MICROBIOLOGY, 45(3), 891-896. doi:10.1128/JCM.01919-06

    DOI: 10.1128/JCM.01919-06

    Effect of chloroquine on reducing HIV-I replication in vitro and the DC-SIGN mediated transfer of virus to CD4+ T-lymphocytes (Journal article)

    Naarding, M. A., Baan, E., Pollakis, G., & Paxton, W. A. (2007). Effect of chloroquine on reducing HIV-I replication in vitro and the DC-SIGN mediated transfer of virus to CD4+ T-lymphocytes. RETROVIROLOGY, 4. doi:10.1186/1742-4690-4-6

    DOI: 10.1186/1742-4690-4-6

    2006

    Interaction of HIV-1 with dendritic cell-specific intercellular adhesion molecule-3-grabbing nonintegrin-expressing cells is influenced by gp120 envelope modifications associated with disease progression (Journal article)

    Nabatov, A. A., van Montfort, T., Geijtenbeek, T. B. H., Pollakis, G., & Paxton, W. A. (2006). Interaction of HIV-1 with dendritic cell-specific intercellular adhesion molecule-3-grabbing nonintegrin-expressing cells is influenced by gp120 envelope modifications associated with disease progression. FEBS JOURNAL, 273(21), 4944-4958. doi:10.1111/j.1742-4658.2006.05491.x

    DOI: 10.1111/j.1742-4658.2006.05491.x

    Bile salt-stimulated lipase from human milk binds DC-SIGN and inhibits human immunodeficiency virus type 1 transfer to CD4(+) T cells (Journal article)

    Naarding, M. A., Dirac, A. M., Ludwig, I. S., Speijer, D., Lindquist, S., Vestman, E. -L., . . . Paxton, W. A. (2006). Bile salt-stimulated lipase from human milk binds DC-SIGN and inhibits human immunodeficiency virus type 1 transfer to CD4(+) T cells. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 50(10), 3367-3374. doi:10.1128/AAC.00593-06

    DOI: 10.1128/AAC.00593-06

    CTL escape and increased viremia irrespective of HIV-specific CD4(+) T-helper responses in two HIV-infected individuals (Journal article)

    Geels, M. J., Jansen, C. A., Baan, E., De Cuyper, I. M., van Schijndel, G. J. M., Schuitemaker, H., . . . van Baarle, D. (2006). CTL escape and increased viremia irrespective of HIV-specific CD4(+) T-helper responses in two HIV-infected individuals. VIROLOGY, 345(1), 209-219. doi:10.1016/j.virol.2005.09.023

    DOI: 10.1016/j.virol.2005.09.023

    2005

    Surveillance technology for HIV-1 subtype C in ethiopia: An env-based NASBA molecular beacon assay to discriminate between subcluster C and C ' (Journal article)

    Ayele, W., de Baar, M. P., Goudsmit, J., Kliphuis, A., Tilahun, T., Dorigo-Zetsma, W., . . . Pollakis, G. (2005). Surveillance technology for HIV-1 subtype C in ethiopia: An env-based NASBA molecular beacon assay to discriminate between subcluster C and C '. JOURNAL OF VIROLOGICAL METHODS, 130(1-2), 22-29. doi:10.1016/j.jviromet.2005.05.028

    DOI: 10.1016/j.jviromet.2005.05.028

    Lewis X component in human milk binds DC-SIGN and inhibits HIV-1 transfer to CD4(+) T lymphocytes (Journal article)

    Naarding, M. A., Ludwig, I. S., Groot, F., Berkhout, B., Geijtenbeek, T. B. H., Pollakis, G., & Paxton, W. A. (2005). Lewis X component in human milk binds DC-SIGN and inhibits HIV-1 transfer to CD4(+) T lymphocytes. JOURNAL OF CLINICAL INVESTIGATION, 115(11), 3256-3264. doi:10.1172/JCI25105

    DOI: 10.1172/JCI25105

    Broad cross-glade T-cell responses to gag in individuals infected with human immunodeficiency virus type 1 non-B clades (A to G): Importance of HLA anchor residue conservation (Journal article)

    Geels, M. J., Dubey, S. A., Anderson, K., Baan, E., Bakker, M., Pollakis, G., . . . Goudsmit, J. (2005). Broad cross-glade T-cell responses to gag in individuals infected with human immunodeficiency virus type 1 non-B clades (A to G): Importance of HLA anchor residue conservation. JOURNAL OF VIROLOGY, 79(17), 11247-11258. doi:10.1128/JVI.79.17.11247-11258.2005

    DOI: 10.1128/JVI.79.17.11247-11258.2005

    Evidence of genetic variability of human immunodeficiency virus type 1 in plasma and cervicovaginal lavage in Ethiopian women seeking care for sexually transmitted infections (Journal article)

    Adal, M., Ayele, W., Wolday, D., Dagne, K., Messele, T., Tilahun, T., . . . Dorigo-Zetsma, W. (2005). Evidence of genetic variability of human immunodeficiency virus type 1 in plasma and cervicovaginal lavage in Ethiopian women seeking care for sexually transmitted infections. AIDS RESEARCH AND HUMAN RETROVIRUSES, 21(7), 649-653. doi:10.1089/aid.2005.21.649

    DOI: 10.1089/aid.2005.21.649

    2004

    Development of a nucleic acid sequence-based amplification assay that uses gag-based molecular beacons to distinguish between human immunodeficiency virus type 1 subtype C and C ' infections in Ethiopia (Journal article)

    Ayele, W., Pollakis, G., Abebe, A., Fisseha, B., Tegbaru, B., Tesfaye, G., . . . de Baar, M. P. (2004). Development of a nucleic acid sequence-based amplification assay that uses gag-based molecular beacons to distinguish between human immunodeficiency virus type 1 subtype C and C ' infections in Ethiopia. JOURNAL OF CLINICAL MICROBIOLOGY, 42(4), 1534-1541. doi:10.1128/JCM.42.4.1534-1541.2004

    DOI: 10.1128/JCM.42.4.1534-1541.2004

    Human immunodeficiency virus type 1 subtypes have a distinct long terminal repeat that determines the replication rate in a host-cell-specific manner (Journal article)

    van Opijnen, T., Jeeninga, R. E., Boerlijst, M. C., Pollakis, G. P., Zetterberg, V., Salminen, M., & Berkhout, B. (2004). Human immunodeficiency virus type 1 subtypes have a distinct long terminal repeat that determines the replication rate in a host-cell-specific manner. JOURNAL OF VIROLOGY, 78(7), 3675-3683. doi:10.1128/JVI.78.7.3675-3683.2004

    DOI: 10.1128/JVI.78.7.3675-3683.2004

    Phenotypic and genotypic comparisons of CCR5- and CXCR4-Tropic human immunodeficiency virus type 1 biological clones isolated from subtype C-infected individuals (Journal article)

    Pollakis, G., Abebe, A., Kliphuis, A., Chalaby, M. I. M., Bakker, M., Mengistu, Y., . . . Paxton, W. A. (2004). Phenotypic and genotypic comparisons of CCR5- and CXCR4-Tropic human immunodeficiency virus type 1 biological clones isolated from subtype C-infected individuals. JOURNAL OF VIROLOGY, 78(6), 2841-2852. doi:10.1128/JVI.78.6.2841-2852.2004

    DOI: 10.1128/JVI.78.6.2841-2852.2004

    Intrapatient alterations in the human immunodeficiency virus type 1 gp120 V1V2 and V3 regions differentially modulate coreceptor usage, virus inhibition by CC/CXC chemokines, soluble CD4, and the b12 and 2G12 monoclonal antibodies (Journal article)

    Nabatov, A. A., Pollakis, G., Linnemann, T., Kliphius, A., Chalaby, M. I. M., & Paxton, W. A. (2004). Intrapatient alterations in the human immunodeficiency virus type 1 gp120 V1V2 and V3 regions differentially modulate coreceptor usage, virus inhibition by CC/CXC chemokines, soluble CD4, and the b12 and 2G12 monoclonal antibodies. JOURNAL OF VIROLOGY, 78(1), 524-530. doi:10.1128/JVI.78.1.524-530.2004

    DOI: 10.1128/JVI.78.1.524-530.2004

    Rapid CD4(+) T-lymphocyte depletion in rhesus monkeys infected with a simian-human immunodeficiency virus expressing the envelope glycoproteins of a primary dual-tropic Ethiopian clade C HIV type 1 isolate (Journal article)

    Cayabyab, M., Rohne, D., Pollakis, G., Mische, C., Messele, T., Abebe, A., . . . Sodroski, J. (2004). Rapid CD4(+) T-lymphocyte depletion in rhesus monkeys infected with a simian-human immunodeficiency virus expressing the envelope glycoproteins of a primary dual-tropic Ethiopian clade C HIV type 1 isolate. AIDS RESEARCH AND HUMAN RETROVIRUSES, 20(1), 27-40. doi:10.1089/088922204322749477

    DOI: 10.1089/088922204322749477

    2003

    Recombination of HIV type 1C (C '/C '') in Ethiopia: Possible link of EthHIV-1C ' to subtype C sequences from the high-prevalence epidemics in India and southern Africa (Journal article)

    Pollakis, G., Abebe, A., Kliphuis, A., De Wit, T. F. R., Fisseha, B., Tegbaru, B., . . . Goudsmit, J. (2003). Recombination of HIV type 1C (C '/C '') in Ethiopia: Possible link of EthHIV-1C ' to subtype C sequences from the high-prevalence epidemics in India and southern Africa. AIDS RESEARCH AND HUMAN RETROVIRUSES, 19(11), 999-1008. doi:10.1089/088922203322588350

    DOI: 10.1089/088922203322588350

    HIV type 1 C and C ' subclusters based on long terminal repeat sequences in the Ethiopian HIV type 1 subtype C epidemic (Journal article)

    De Baar, M. P., Abebe, A., Kliphuis, A., Tesfaye, G., Goudsmit, J., & Pollakis, G. (2003). HIV type 1 C and C ' subclusters based on long terminal repeat sequences in the Ethiopian HIV type 1 subtype C epidemic. AIDS RESEARCH AND HUMAN RETROVIRUSES, 19(10), 917-922. doi:10.1089/088922203322493094

    DOI: 10.1089/088922203322493094

    2002

    Primary HIV-1 subtype C infection in Ethiopia (Journal article)

    de Wit, T. F. R., Tsegaye, A., Wolday, D., Hailu, B., Aklilu, M., Sanders, E., . . . Fontanet, A. L. (2002). Primary HIV-1 subtype C infection in Ethiopia. JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, 30(5), 463-470. doi:10.1097/01.QAI.0000026915.39197.99

    DOI: 10.1097/01.QAI.0000026915.39197.99

    Primary HIV-1 subtype C infection in Ethiopia. (Journal article)

    Rinke de Wit, T. F., Tsegaye, A., Wolday, D., Hailu, B., Aklilu, M., Sanders, E., . . . Fontanet, A. L. (2002). Primary HIV-1 subtype C infection in Ethiopia.. Journal of acquired immune deficiency syndromes (1999), 30(5), 463-470. doi:10.1097/00126334-200208150-00001

    DOI: 10.1097/00126334-200208150-00001

    2001

    Timing of the HIV-1 subtype C epidemic in Ethiopia based on early virus strains and subsequent virus diversification (Journal article)

    Abebe, A., Lukashov, V. V., Pollakis, G., Kliphuis, A., Fontanet, A. L., Goudsmit, J., & de Wit, T. F. R. (2001). Timing of the HIV-1 subtype C epidemic in Ethiopia based on early virus strains and subsequent virus diversification. AIDS, 15(12), 1555-1561. doi:10.1097/00002030-200108170-00013

    DOI: 10.1097/00002030-200108170-00013

    Timing of the introduction into ethiopia of subcluster C ' of HIV type 1 subtype C (Journal article)

    Abebe, A., Lukashov, V. V., de Wit, T. F. R., Fisseha, B., Tegbaru, B., Kliphuis, A., . . . Pollakis, G. (2001). Timing of the introduction into ethiopia of subcluster C ' of HIV type 1 subtype C. AIDS RESEARCH AND HUMAN RETROVIRUSES, 17(7), 657-661. doi:10.1089/088922201300119770

    DOI: 10.1089/088922201300119770

    N-linked glycosylation of the HIV type-1 gp120 envelope glycoprotein as a major determinant of CCR5 and CXCR4 coreceptor utilization (Journal article)

    Pollakis, G., Kang, S., Kliphuis, A., Chalaby, M. I. M., Goudsmit, J., & Paxton, W. A. (2001). N-linked glycosylation of the HIV type-1 gp120 envelope glycoprotein as a major determinant of CCR5 and CXCR4 coreceptor utilization. JOURNAL OF BIOLOGICAL CHEMISTRY, 276(16), 13433-13441. doi:10.1074/jbc.M009779200

    DOI: 10.1074/jbc.M009779200

    2000

    Identification of a genetic subcluster of HIV type 1 subtype C (C ') widespread in Ethiopia (Journal article)

    Abebe, A., Pollakis, G., Fontanet, A. L., Fisseha, B., Tegbaru, B., Kliphuis, A., . . . De Wit, T. F. R. (2000). Identification of a genetic subcluster of HIV type 1 subtype C (C ') widespread in Ethiopia. AIDS RESEARCH AND HUMAN RETROVIRUSES, 16(17), 1909-1914. doi:10.1089/08892220050195865

    DOI: 10.1089/08892220050195865

    HIV-1 subtype C in commercial sex workers in Addis Ababa, Ethiopia (Journal article)

    Hussein, M., Abebe, A., Pollakis, G., Brouwer, M., Petros, B., Fontanet, A. L., & de Wit, T. F. R. (2000). HIV-1 subtype C in commercial sex workers in Addis Ababa, Ethiopia. JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, 23(2), 120-127. Retrieved from http://gateway.webofknowledge.com/

    1999

    HIV-1 subtype C syncytium- and non-syncytium-inducing phenotypes and coreceptor usage among Ethiopian patients with AIDS (Journal article)

    Abebe, A., Demissie, D., Goudsmit, J., Brouwer, M., Kuiken, C. L., Pollakis, G., . . . de Wit, T. F. R. (1999). HIV-1 subtype C syncytium- and non-syncytium-inducing phenotypes and coreceptor usage among Ethiopian patients with AIDS. AIDS, 13(11), 1305-1311. doi:10.1097/00002030-199907300-00006

    DOI: 10.1097/00002030-199907300-00006

    1995

    COMPETITION BETWEEN INHIBITORS OF THE TRYPANOSOME ALTERNATIVE OXIDASE (TAO) AND REDUCED COENZYME Q(9) (Journal article)

    POLLAKIS, G., GRADY, R. W., DIECK, H. A., & CLARKSON, A. B. (1995). COMPETITION BETWEEN INHIBITORS OF THE TRYPANOSOME ALTERNATIVE OXIDASE (TAO) AND REDUCED COENZYME Q(9). BIOCHEMICAL PHARMACOLOGY, 50(8), 1207-1210. doi:10.1016/0006-2952(95)00259-3

    DOI: 10.1016/0006-2952(95)00259-3

    1993

    NON-CYTOCHROME MEDIATED MITOCHONDRIAL ATP PRODUCTION IN BLOOD-STREAM FORM TRYPANOSOMA-BRUCEI-BRUCEI (Journal article)

    BIENEN, E. J., MATURI, R. K., POLLAKIS, G., & CLARKSON, A. B. (1993). NON-CYTOCHROME MEDIATED MITOCHONDRIAL ATP PRODUCTION IN BLOOD-STREAM FORM TRYPANOSOMA-BRUCEI-BRUCEI. EUROPEAN JOURNAL OF BIOCHEMISTRY, 216(1), 75-80. doi:10.1111/j.1432-1033.1993.tb18118.x

    DOI: 10.1111/j.1432-1033.1993.tb18118.x

    1991

    MITOCHONDRIAL DEVELOPMENT IN TRYPANOSOMA-BRUCEI-BRUCEI TRANSITIONAL BLOOD-STREAM FORMS (Journal article)

    BIENEN, E. J., SARIC, M., POLLAKIS, G., GRADY, R. W., & CLARKSON, A. B. (1991). MITOCHONDRIAL DEVELOPMENT IN TRYPANOSOMA-BRUCEI-BRUCEI TRANSITIONAL BLOOD-STREAM FORMS. MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 45(2), 185-192. doi:10.1016/0166-6851(91)90085-K

    DOI: 10.1016/0166-6851(91)90085-K

    1989

    RESPIRATION OF BLOOD-STREAM FORMS OF THE PARASITE TRYPANOSOMA-BRUCEI-BRUCEI IS DEPENDENT ON A PLANT-LIKE ALTERNATIVE OXIDASE (Journal article)

    CLARKSON, A. B., BIENEN, E. J., POLLAKIS, G., & GRADY, R. W. (1989). RESPIRATION OF BLOOD-STREAM FORMS OF THE PARASITE TRYPANOSOMA-BRUCEI-BRUCEI IS DEPENDENT ON A PLANT-LIKE ALTERNATIVE OXIDASE. JOURNAL OF BIOLOGICAL CHEMISTRY, 264(30), 17770-17776. Retrieved from http://gateway.webofknowledge.com/

    TRYPANOCIDAL COQ ANALOGS - THEIR EFFECT ON OTHER MITOCHONDRIAL SYSTEMS (Journal article)

    CLARKSON, A. B., BIENEN, E. J., POLLAKIS, G., & GRADY, R. W. (1989). TRYPANOCIDAL COQ ANALOGS - THEIR EFFECT ON OTHER MITOCHONDRIAL SYSTEMS. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY, 94(2), 245-251. doi:10.1016/0305-0491(89)90341-6

    DOI: 10.1016/0305-0491(89)90341-6

    1988

    A NEW CLASS OF FREE-RADICAL SCAVENGERS REDUCING ADRIAMYCIN MITOCHONDRIAL TOXICITY (Journal article)

    PRAET, M., CALDERON, P. B., POLLAKIS, G., ROBERFROID, M., & RUYSSCHAERT, J. M. (1988). A NEW CLASS OF FREE-RADICAL SCAVENGERS REDUCING ADRIAMYCIN MITOCHONDRIAL TOXICITY. BIOCHEMICAL PHARMACOLOGY, 37(24), 4617-4622. doi:10.1016/0006-2952(88)90329-2

    DOI: 10.1016/0006-2952(88)90329-2

    1986

    INVIVO AND INVITRO MODIFICATIONS OF THE MITOCHONDRIAL-MEMBRANE INDUCED BY 4' EPI-ADRIAMYCIN (Journal article)

    PRAET, M., LAGHMICHE, M., POLLAKIS, G., GOORMAGHTIGH, E., & RUYSSCHAERT, J. M. (1986). INVIVO AND INVITRO MODIFICATIONS OF THE MITOCHONDRIAL-MEMBRANE INDUCED BY 4' EPI-ADRIAMYCIN. BIOCHEMICAL PHARMACOLOGY, 35(17), 2923-2928. doi:10.1016/0006-2952(86)90487-9

    DOI: 10.1016/0006-2952(86)90487-9

    1984

    DAMAGES OF THE MITOCHONDRIAL-MEMBRANE IN ADRIAMYCIN TREATED MICE (Journal article)

    PRAET, M., POLLAKIS, G., GOORMAGHTIGH, E., & RUYSSCHAERT, J. M. (1984). DAMAGES OF THE MITOCHONDRIAL-MEMBRANE IN ADRIAMYCIN TREATED MICE. CANCER LETTERS, 25(1), 89-96. doi:10.1016/S0304-3835(84)80030-0

    DOI: 10.1016/S0304-3835(84)80030-0

    ADRIAMYCIN AND DERIVATIVES INTERACTION WITH THE MITOCHONDRIAL-MEMBRANE - O-2 CONSUMPTION AND FREE-RADICALS FORMATION (Journal article)

    POLLAKIS, G., GOORMAGHTIGH, E., DELMELLE, M., LION, Y., & RUYSSCHAERT, J. M. (1984). ADRIAMYCIN AND DERIVATIVES INTERACTION WITH THE MITOCHONDRIAL-MEMBRANE - O-2 CONSUMPTION AND FREE-RADICALS FORMATION. RESEARCH COMMUNICATIONS IN CHEMICAL PATHOLOGY AND PHARMACOLOGY, 44(3), 445-459. Retrieved from http://gateway.webofknowledge.com/

    1983

    ROLE OF THE QUINONE STRUCTURE IN THE MITOCHONDRIAL DAMAGE INDUCED BY ANTI-TUMOR ANTHRACYCLINES - COMPARISON OF ADRIAMYCIN AND 5-IMINODAUNORUBICIN (Journal article)

    POLLAKIS, G., GOORMAGHTIGH, E., & RUYSSCHAERT, J. M. (1983). ROLE OF THE QUINONE STRUCTURE IN THE MITOCHONDRIAL DAMAGE INDUCED BY ANTI-TUMOR ANTHRACYCLINES - COMPARISON OF ADRIAMYCIN AND 5-IMINODAUNORUBICIN. FEBS LETTERS, 155(2), 267-272. doi:10.1016/0014-5793(82)80618-2

    DOI: 10.1016/0014-5793(82)80618-2

    MITOCHONDRIAL-MEMBRANE MODIFICATIONS INDUCED BY ADRIAMYCIN-MEDIATED ELECTRON-TRANSPORT (Journal article)

    GOORMAGHTIGH, E., POLLAKIS, G., & RUYSSCHAERT, J. M. (1983). MITOCHONDRIAL-MEMBRANE MODIFICATIONS INDUCED BY ADRIAMYCIN-MEDIATED ELECTRON-TRANSPORT. BIOCHEMICAL PHARMACOLOGY, 32(5), 889-893. doi:10.1016/0006-2952(83)90593-2

    DOI: 10.1016/0006-2952(83)90593-2