Dr Valentina Barrera PhD

Postdoctoral Research Associate Eye and Vision Science

Publications

2019

Neutrophil extracellular traps drive inflammatory pathogenesis in malaria (Journal article)

Knackstedt, S. L., Georgiadou, A., Apel, F., Abu-Abed, U., Moxon, C. A., Cunnington, A. J., . . . Amulic, B. (2019). Neutrophil extracellular traps drive inflammatory pathogenesis in malaria. SCIENCE IMMUNOLOGY, 4(40). doi:10.1126/sciimmunol.aaw0336

DOI: 10.1126/sciimmunol.aaw0336

LaNt alpha 31 influences cell adhesion and migration through modulation of laminin organisation and hemidesmosome maturation (Conference Paper)

Troughton, L. D., Iorio, V., Barrera, V., Shaw, L., Zech, T., Risk, J., & Hamill, K. J. (2019). LaNt alpha 31 influences cell adhesion and migration through modulation of laminin organisation and hemidesmosome maturation. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 100 (pp. A38-A39). Retrieved from http://gateway.webofknowledge.com/

Preserved neural extracellular matrix in decellularised human femoral nerve: towards developing a new allograft for peripheral nerve injury in the UK (Conference Paper)

Barrera, V., Webster, G., Joseph, A., Hogg, P., Hall, R., Kearney, J. N., . . . Rooney, P. (2019). Preserved neural extracellular matrix in decellularised human femoral nerve: towards developing a new allograft for peripheral nerve injury in the UK. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 100 (pp. A11-A12). Retrieved from http://gateway.webofknowledge.com/

Comparison of CD8(+) T Cell Accumulation in the Brain During Human and Murine Cerebral Malaria (Journal article)

Barrera, V., Haley, M. J., Strangward, P., Attree, B., Kamiza, S., Seydel, K. B., . . . Couper, K. N. (2019). Comparison of CD8(+) T Cell Accumulation in the Brain During Human and Murine Cerebral Malaria. FRONTIERS IN IMMUNOLOGY, 10. doi:10.3389/fimmu.2019.01747

DOI: 10.3389/fimmu.2019.01747

2018

LaNt alpha 31, a novel regulator of basement membrane assembly (Conference Paper)

Troughton, L. D., Iorio, V., Barrera, V., & Hamill, K. J. (2018). LaNt alpha 31, a novel regulator of basement membrane assembly. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 99 (pp. A32-A33). Retrieved from http://gateway.webofknowledge.com/

Differential Distribution of Laminin N-Terminus alpha 31 Across the Ocular Surface: Implications for Corneal Wound Repair (vol 59, pg 4082, 2018) (Journal article)

Barrera, V., Troughton, L. D., Iorio, V., Liu, S., Oyewole, O., Sheridan, C. M., & Hamill, K. J. (2018). Differential Distribution of Laminin N-Terminus alpha 31 Across the Ocular Surface: Implications for Corneal Wound Repair (vol 59, pg 4082, 2018). INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 59(11), 4463. doi:10.1167/iovs.18-24037a

DOI: 10.1167/iovs.18-24037a

A splicing switch provides dual layer control of laminin alpha3: Implications for squamous cell carcinoma (Conference Paper)

Troughton, L. D., Barrera, V., Brown, L., Zech, T., Willoughby, C. E., Risk, J. M., & Hamill, K. J. (2018). A splicing switch provides dual layer control of laminin alpha3: Implications for squamous cell carcinoma. In JOURNAL OF INVESTIGATIVE DERMATOLOGY Vol. 138 (pp. S147). Retrieved from http://gateway.webofknowledge.com/

Neurovascular sequestration in paediatric P. falciparum malaria is visible clinically in the retina (Journal article)

Barrera, V., MacCormick, I. J. C., Czanner, G., Hiscott, P. S., White, V. A., Craig, A. G., . . . Harding, S. P. (2018). Neurovascular sequestration in paediatric P. falciparum malaria is visible clinically in the retina. ELIFE, 7. doi:10.7554/eLife.32208

DOI: 10.7554/eLife.32208

2016

LaNt alpha 31: a new regulator of corneal epithelial cell migration (Conference Paper)

Troughton, L. D., Iorio, V., Barrera, V., Sharif, U., & Hamill, K. J. (2016). LaNt alpha 31: a new regulator of corneal epithelial cell migration. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 97 (pp. A28). Retrieved from http://gateway.webofknowledge.com/

2015

Severity of Retinopathy Parallels the Degree of Parasite Sequestration in the Eyes and Brains of Malawian Children With Fatal Cerebral Malaria (Journal article)

Barrera, V., Hiscott, P. S., Craig, A. G., White, V. A., Milner, D. A., Beare, N. A. V., . . . Harding, S. P. (2015). Severity of Retinopathy Parallels the Degree of Parasite Sequestration in the Eyes and Brains of Malawian Children With Fatal Cerebral Malaria. JOURNAL OF INFECTIOUS DISEASES, 211(12), 1977-1986. doi:10.1093/infdis/jiu592

DOI: 10.1093/infdis/jiu592

2014

Cerebral malaria in children: using the retina to study the brain (Journal article)

MacCormick, I. J. C., Beare, N. A. V., Taylor, T. E., Barrera, V., White, V. A., Hiscott, P., . . . Harding, S. P. (2014). Cerebral malaria in children: using the retina to study the brain. BRAIN, 137, 2119-2142. doi:10.1093/brain/awu001

DOI: 10.1093/brain/awu001

Malarial pigment hemozoin impairs chemotactic motility and transendothelial migration of monocytes via 4-hydroxynonenal (Journal article)

Skorokhod, O. A., Barrera, V., Heller, R., Carta, F., Turrini, F., Arese, P., & Schwarzer, E. (2014). Malarial pigment hemozoin impairs chemotactic motility and transendothelial migration of monocytes via 4-hydroxynonenal. Free Radical Biology and Medicine, 75, 210-221. doi:10.1016/j.freeradbiomed.2014.07.004

DOI: 10.1016/j.freeradbiomed.2014.07.004

Reply: Retinopathy, histidine-rich protein-2 and perfusion pressure in cerebral malaria (Journal article)

MacCormick, I. J. C., Beare, N. A. V., Taylor, T. E., Barrera, V., White, V. A., Hiscott, P., . . . Harding, S. P. (2014). Reply: Retinopathy, histidine-rich protein-2 and perfusion pressure in cerebral malaria. BRAIN, 137. doi:10.1093/brain/awu146

DOI: 10.1093/brain/awu146

2013

Intensity of Parasite Sequestration in Retinal Vessels Correlates with Severity of Retinopathy in Malawian Children with Cerebral Malaria: a Histopathological Study (Conference Paper)

Barrera, V., Hiscott, P. S., Beare, N. A. V., Craig, A. G., White, V. A., MacCormick, I. J. C., . . . Harding, S. P. (2013). Intensity of Parasite Sequestration in Retinal Vessels Correlates with Severity of Retinopathy in Malawian Children with Cerebral Malaria: a Histopathological Study. In American Society of Tropical Medicine and Hygiene (ASTMH) Annual conference (pp. 274). Washington DC, USA: ..

Intensity of parasite sequestration in retinal vessels correlates with severity of retinopathy in malawian children with cerebral malaria: a histopathological study. (Presentation material)

Barrera, V., Hiscott, P. S., Beare, N. A. V., Craig, A. G., White, V. A., MacCormick, I. J. C., . . . Harding, S. P. (2013). Intensity of parasite sequestration in retinal vessels correlates with severity of retinopathy in malawian children with cerebral malaria: a histopathological study..

Malaria Pigment (Hemozoin) and Extravasated Fibrinogen are Associated with Retinal Vessel Leakage and Hemorrhages in Malawian Children with Cerebral Malaria (Conference Paper)

Barrera, V., Hiscott, P. S., Beare, N. A. V., Craig, A. G., White, V. A., MacCormick, I. J. C., . . . Harding, S. P. (2013). Malaria Pigment (Hemozoin) and Extravasated Fibrinogen are Associated with Retinal Vessel Leakage and Hemorrhages in Malawian Children with Cerebral Malaria. In ASTMH Annual conference (pp. 274). Washington DC, USA: ..

Malaria pigment (hemozoin) and extravasated fibrinogen are associated with retinal vessel leakage and hemorrhages in malawian children with cerebral malaria. (Presentation material)

Barrera, V., Hiscott, P. S., Beare, N. A. V., Craig, A. G., White, V. A., MacCormick, I. J. C., . . . Harding, S. P. (2013). Malaria pigment (hemozoin) and extravasated fibrinogen are associated with retinal vessel leakage and hemorrhages in malawian children with cerebral malaria..

2012

Impaired migration of hemozoin-fed human monocytes: impact of 4-hydroxynonenal (Conference Paper)

Skorokhod, O., Barrera, V., Heller, R., Carta, F., Turrini, F., Arese, P., & Schwarzer, E. (2012). Impaired migration of hemozoin-fed human monocytes: impact of 4-hydroxynonenal. In Society for Free Radical Research (SFRR) International Biennal Conference (pp. .). London, UK: ..

Platelet surface high mobility group box protein-1 binds receptor for advanced glycation endproducts in plasma or on monocytes in septic patients (Conference Paper)

Thachil, J., Barrera, V., Djebabri, B., Abrams, S., Wang, G., & Toh, C. H. (2012). Platelet surface high mobility group box protein-1 binds receptor for advanced glycation endproducts in plasma or on monocytes in septic patients. In Annual Meeting of the Scientific and Standardization Committee of the International Society of Thrombosis and Haemostasis (ISTH) (pp. .). Liverpool, UK: ..

2011

Host fibrinogen stably bound to hemozoin rapidly activates monocytes via TLR-4 and CD11b/CD18-integrin. A new paradigm of hemozoin action (Journal article)

Barrera, V., Skorokhod, O., Baci, D., Gremo, G., Arese, P., & Schwarzer, E. (2011). Host fibrinogen stably bound to hemozoin rapidly activates monocytes via TLR-4 and CD11b/CD18-integrin. A new paradigm of hemozoin action. Blood, 117(21), 5674-5682.

2010

Inhibition of erythropoiesis in malaria anemia. Role of hemozoin and hemozoin-generated 4-hydroxynonenal (Journal article)

Skorokhod, O., Caione, L., Marrocco, T., Migliardi, G., Barrera, V., Arese, P., . . . Schwarzer, E. (2010). Inhibition of erythropoiesis in malaria anemia. Role of hemozoin and hemozoin-generated 4-hydroxynonenal. Blood, 116(20), 4328-4337.

Transfer of 4-hydroxynonenal, a inhibitory hemozoin (HZ) product, from HZ or HZ-laden phagocytes to developing human erythroid cells. A model for erythropoiesis inhibition in malaria anemia (Journal article)

Skorokhod, O. A., Caione, L., Migliardi, G., Barrera, V., Piacibello, W., Schwarzer, E., & Arese, P. (2010). Transfer of 4-hydroxynonenal, a inhibitory hemozoin (HZ) product, from HZ or HZ-laden phagocytes to developing human erythroid cells. A model for erythropoiesis inhibition in malaria anemia. Malaria Journal, 9(S2). doi:10.1186/1475-2875-9-s2-o28

DOI: 10.1186/1475-2875-9-s2-o28

2009

Fibrinogen as bioactive signal molecule in the immune response to hemozoin (Conference Paper)

Barrera, V., Arese, P., Turrini, F., & Schwarzer, E. (2009). Fibrinogen as bioactive signal molecule in the immune response to hemozoin. In Biology and Pathology of the Malaria Parasite (BioMalPar) conference (pp. .). Heidelberg, Germany: ..

2008

Hemozoin and the human monocyte--a brief review of their interactions (Journal article)

Schwarzer, E., Skorokhod, O., Barrera, V., Prato, M., & Arese, P. (2008). Hemozoin and the human monocyte--a brief review of their interactions. Parassitologia, 50(1-2), 143-145.