Prof Robert Moots BSc (hons), MB BS (hons), PhD, FRCP

Professor of Rheumatology (Clin,Hcc) Musculoskeletal Biology I

    Research

    Research Interest 1

    Inflammatory rheumatic diseases (rheumatoid arthritis, scleroderma. Behcet's). Clinical assessment, immunotherapy and molecular immunology. T cells NK cells and neutrophils

    Research Grants

    A Novel mechanism for control of apoptosis via post-translational modifiction of Mcl-1

    ARTHRITIS RESEARCH CAMPAIGN

    June 2008 - August 2011

    Changes in neutrophil gene expression during active and resolved inflammation

    ARTHRITIS RESEARCH UK

    December 2010 - April 2014

    Immunotherapy in inflammatory arthritis.

    AINTREE UNIVERSITY HOSPITAL NHS FOUNDATION TRUST (UK)

    April 2005 - December 2011

    UKIERI-UGC Thamatic partnerships

    BRITISH COUNCIL (UK)

    March 2013 - September 2015

    Body effect of metabolism on risk of cardiovascular disease in rheumatoid arthritis.

    AINTREE UNIVERSITY HOSPITAL NHS FOUNDATION TRUST (CHARITY) (UK)

    January 2004 - June 2005

    T Cell Responses to Type II Collagen and Molecular Mimicry in Rheumatoid Arthritis.

    ARTHRITIS RESEARCH CAMPAIGN

    July 1999 - October 2002

    The Innate Immune System in Scleroderma.

    RAYNAUD'S & SCLERODERMA ASSOCIATION (UK)

    November 2005 - October 2008

    Rheumatology Research Fellowship: Sadik.

    AINTREE UNIVERSITY HOSPITAL NHS FOUNDATION TRUST (CHARITY) (UK)

    April 2005 - October 2006

    The functional characterisation of natural killer cells accumulating in the synovial fluid in patients with rheumatoid arthritis.

    ARTHRITIS RESEARCH CAMPAIGN

    December 2000 - November 2003

    CASE: A systems based approach to studying neutrophil gene expression

    UCB PHARMA LTD (UK)

    October 2010 - March 2015

    Extension for Sarang Chitale to continue research into clinical aspects of inflammatory arthritis

    AINTREE UNIVERSITY HOSPITAL NHS FOUNDATION TRUST (UK)

    October 2010 - October 2011

    ARC Senior Lecturer (Clinical) in Rheumatology.

    ARTHRITIS RESEARCH CAMPAIGN

    May 2004 - March 2009

    Molecular Mimicry in Insulin-Dependent Diabetes Mellitus.

    DIABETIC CHILDRENS APPEAL (UK)

    September 1999 - September 2004

    Musculoskeletal ultrasound machine

    JOHN WYETH & BROTHER LIMITED (UK)

    July 2008 - July 2009

    The development of a novel mechanism to inhibit neutrophil function selectively as a therapy for rheumatoid arthritis.

    AINTREE UNIVERSITY HOSPITAL NHS FOUNDATION TRUST (UK)

    December 2003 - March 2006

    The relationship between oxygen concentrations and apoptosis in the joints of patients with rheumatoid arthritis.

    AINTREE UNIVERSITY HOSPITAL NHS FOUNDATION TRUST (CHARITY) (UK)

    October 2003 - September 2006

    Development of musculoskeletal research collaborations

    AINTREE UNIVERSITY HOSPITAL NHS FOUNDATION TRUST (UK)

    May 2013 - December 2017

    Investigating neutrophil function in juvenile onset systemic lupus erythematosus.

    ARTHRITIS RESEARCH CAMPAIGN

    April 2007 - March 2008

    Comparison of neutrophil protein expression between patients with systemic sclerosis and controls.

    MEDICAL RESEARCH COUNCIL (MRC)

    November 2006 - October 2009

    Post-doctoral Fellowship in Rheumatology.

    AINTREE UNIVERSITY HOSPITAL NHS FOUNDATION TRUST (CHARITY) (UK)

    November 2001 - October 2002

    2) BIO BEHÇET’S Optimal utilisation of biologic drugs in Behçet’s Disease: a randomised controlled trial of infliximab vs alpha interferon, with genotyping and metabolomic profiling, towards a stratified medicines approach to treatment.

    DEPARTMENT OF HEALTH (UK) (NIHR)

    January 2015 - June 2021

    Neutrophil function in rheumatoid arthritis: relation to inflammatory burden and therapeutic intervention

    AINTREE UNIVERSITY HOSPITAL NHS FOUNDATION TRUST (UK)

    October 2009 - September 2010

    Aintree Contribution to Research

    AINTREE UNIVERSITY HOSPITAL NHS FOUNDATION TRUST (UK)

    August 2005 - October 2006

    Functional phosphoproteomics to analyse signalling networks regulated by Fc gamma receptors.

    ARTHRITIS RESEARCH CAMPAIGN

    October 2004 - September 2007

    CHROMED

    EUROPEAN COMMISSION

    October 2012 - March 2016

    Aintree Hospitals research support for Prof R J Moots

    AINTREE UNIVERSITY HOSPITAL NHS FOUNDATION TRUST (UK)

    October 2007 - September 2008

    Rheumatology Research.

    AINTREE UNIVERSITY HOSPITAL NHS FOUNDATION TRUST (CHARITY) (UK)

    August 1998 - September 2001

    Additional R&D nurse day (Bee Squires) to support Rob Moots research

    AINTREE UNIVERSITY HOSPITAL NHS FOUNDATION TRUST (UK)

    May 2009 - December 2010

    Postgraduate Studentship.

    AINTREE UNIVERSITY HOSPITAL NHS FOUNDATION TRUST (CHARITY) (UK)

    August 2001 - July 2003

    Neutrophil function in inflammation

    AINTREE UNIVERSITY HOSPITAL NHS FOUNDATION TRUST (UK)

    October 2012 - January 2017

    Castaway Sequencing System.

    BRITISH SJOGREN'S SYNDROME ASSOCIATION

    April 2001 - March 2003

    QUINS Trial.

    ARTHRITIS RESEARCH CAMPAIGN

    March 2006 - September 2007

    Bridging and accelerating the translation of novel scientific findings for health and wealth gain

    MEDICAL RESEARCH COUNCIL (MRC)

    March 2014 - August 2015

    Academic Secretary Grant.

    ARTHRITIS RESEARCH CAMPAIGN

    April 1999 - April 2002

    Rheumatology Clinical Research Fellowship

    JOHN WYETH & BROTHER LIMITED (UK)

    October 2009 - October 2010

    Rheumatology Research: Clinical Research Fellowship

    AINTREE UNIVERSITY HOSPITAL NHS FOUNDATION TRUST (CHARITY) (UK)

    October 2008 - September 2009

    Effects of anti-TNF alpha therapy in rheumatoid arthritis on innate and specific immunity.

    AINTREE UNIVERSITY HOSPITAL NHS FOUNDATION TRUST (CHARITY) (UK)

    April 2002 - January 2005

    Immunological aspects of arthritis.

    AINTREE UNIVERSITY HOSPITAL NHS FOUNDATION TRUST (UK)

    January 2002 - June 2003

    Neutrophil and endothelial interactions in systematic vasculitis.

    MERSEY KIDNEY FIRST (UK)

    October 2000 - September 2003

    Clinical research in respiratory medicine

    AINTREE UNIVERSITY HOSPITAL NHS FOUNDATION TRUST (UK)

    January 2011 - May 2014

    Induction of cancer cell apoptosis by inhibition of NF-kB and COX-2 mediated expression of Mc1-1 using time lapse imaging of individual living cells.

    NORTH WEST CANCER RESEARCH FUND

    February 2005 - January 2008

    Support for Research at the University of Liverpool Academic Rheumatology Unit at Aintree.

    AINTREE UNIVERSITY HOSPITAL NHS FOUNDATION TRUST (UK)

    December 2002 - November 2003

    Dopamine receptor signalling and inflammatory cytokine production by human monocytes.

    THE NUFFIELD FOUNDATION (UK)

    December 2000 - November 2002

    PHD Studentship pain relief foundation - Skin immune changes in Complex Regional Pain Syndrome

    PAIN RELIEF FOUNDATION (UK)

    October 2009 - March 2013

    Does obesity influence treatment in rheumatoid arthritis?

    AINTREE UNIVERSITY HOSPITAL NHS FOUNDATION TRUST (UK)

    January 2013 - July 2014

    ICAC (Integrated Clinical Arthritis Centre) Grant.

    ARTHRITIS RESEARCH CAMPAIGN

    April 2002 - October 2004

    Determining novel mechanisms of joint destruction as biomarker for arthropathy

    LIVERPOOL HEALTH PARTNERS (UK)

    June 2013 - July 2016

    Research Collaborations

    Prof Steven Edwards

    Internal