Professor Rachel Williams BSc MS PhD CEng MIPEM FIMMM

Professor of Ophthalmic Bioengineering Eye & Vision Sciences

+44 (0)151 794 9043
Work email Rlw@liverpool.ac.uk

Publications

Selected Publications

Novel Heavy Tamponade for Vitreoretinal Surgery (Journal article - 2013)
A Novel Peptide Hydrogel for an Antimicrobial Bandage Contact Lens (Journal article - 2016)
The formation of a functional retinal pigment epithelium occurs on porous polytetrafluoroethylene substrates independently of the surface chemistry (Journal article - 2017)
Biomaterials for Regenerative Medicine Approaches for the Anterior Segment of the Eye (Journal article - 2018)
Development of decellularized conjunctiva as a substrate for the ex vivo expansion of conjunctival epithelium (Journal article - 2018)

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2023

FluoroPi Device With SmartProbes: A Frugal Point-of-Care System for Fluorescent Detection of Bacteria From a Pre-Clinical Model of Microbial Keratitis. (Journal article)

Mohanan, S. M. P. C., Russell, K., Duncan, S., Kiang, A., Lochenie, C., Duffy, E., . . . Mills, B. (2023). FluoroPi Device With SmartProbes: A Frugal Point-of-Care System for Fluorescent Detection of Bacteria From a Pre-Clinical Model of Microbial Keratitis.. Translational vision science & technology, 12(7), 1. doi:10.1167/tvst.12.7.1

DOI: 10.1167/tvst.12.7.1

Antimicrobial effect of nitric oxide releasing hydrogels on Staphylococcus aureus derived proteases (Journal article)

Deller, R., Li, M., Doherty, K., Hanson, J., Williams, R., Kolegraff, K., . . . D'Sa, R. (2023). Antimicrobial effect of nitric oxide releasing hydrogels on Staphylococcus aureus derived proteases. Advanced Materials Interfaces, 10(15). doi:10.1002/admi.202202472

DOI: 10.1002/admi.202202472

Antimicrobial Effect of Nitric Oxide Releasing Hydrogels on Staphylococcus Aureus Derived Proteases (Adv. Mater. Interfaces 15/2023) (Journal article)

Deller, R. C., Li, M., Doherty, K. G., Aveyard, J., Williams, R. L., Kolegraff, K. N., . . . D'Sa, R. A. (2023). Antimicrobial Effect of Nitric Oxide Releasing Hydrogels on Staphylococcus Aureus Derived Proteases (Adv. Mater. Interfaces 15/2023). Advanced Materials Interfaces, 10(15). doi:10.1002/admi.202370050

DOI: 10.1002/admi.202370050

The conjunctival extracellular matrix, related disorders and development of substrates for conjunctival restoration (Journal article)

Makuloluwa, A. K., Hamill, K. J., Rauz, S., Bosworth, L., Haneef, A., Romano, V., . . . Kaye, S. B. (2023). The conjunctival extracellular matrix, related disorders and development of substrates for conjunctival restoration. OCULAR SURFACE, 28, 322-335. doi:10.1016/j.jtos.2021.05.011

DOI: 10.1016/j.jtos.2021.05.011

2022

Scaffold-Free Strategy Using a PEG-Dextran Aqueous Two-Phase-System for Corneal Tissue Repair. (Journal article)

Hung, L. T., Poon, S. H. L., Yan, W. H., Lace, R., Zhou, L., Wong, J. K. W., . . . Chan, Y. K. (2022). Scaffold-Free Strategy Using a PEG-Dextran Aqueous Two-Phase-System for Corneal Tissue Repair.. ACS biomaterials science & engineering, 8(5), 1987-1999. doi:10.1021/acsbiomaterials.1c01500

DOI: 10.1021/acsbiomaterials.1c01500

Antimicrobial Nitric Oxide-Releasing Electrospun Dressings for Wound Healing Applications (Journal article)

Li, M., Aveyard, J., Doherty, K. G., Deller, R. C., Williams, R. L., Kolegraff, K. N., . . . D'Sa, R. A. (2022). Antimicrobial Nitric Oxide-Releasing Electrospun Dressings for Wound Healing Applications. ACS MATERIALS AU, 2(2), 190-203. doi:10.1021/acsmaterialsau.1c00056

DOI: 10.1021/acsmaterialsau.1c00056

Amoebicidal Activity of Poly-Epsilon-Lysine Functionalized Hydrogels (Journal article)

Kennedy, S. M., Deshpande, P., Gallagher, A. G., Horsburgh, M. J., Allison, H. E., Kaye, S. B., . . . Williams, R. L. (2022). Amoebicidal Activity of Poly-Epsilon-Lysine Functionalized Hydrogels. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 63(1). doi:10.1167/iovs.63.1.11

DOI: 10.1167/iovs.63.1.11

Using CRISPR-Cas9 generated models to determine the role of laminin a5 polymerisation (Conference Paper)

Shaw, L., Williams, R. L., & Hamill, K. (2022). Using CRISPR-Cas9 generated models to determine the role of laminin a5 polymerisation. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 103 (pp. A13-A14). Retrieved from https://www.webofscience.com/

2021

Melt electro-written scaffolds with box-architecture support orthogonally oriented collagen (Journal article)

Bosworth, L. A., Lanaro, M., O'Loughlin, D. A., D'Sa, R. A., Woodruff, M. A., & Williams, R. L. (2022). Melt electro-written scaffolds with box-architecture support orthogonally oriented collagen. BIOFABRICATION, 14(1). doi:10.1088/1758-5090/ac41a1

DOI: 10.1088/1758-5090/ac41a1

3D reactive inkjet printing of poly-ɛ-lysine/gellan gum hydrogels for potential corneal constructs (Journal article)

Duffy, G. L., Liang, H., Williams, R. L., Wellings, D. A., & Black, K. (2021). 3D reactive inkjet printing of poly-ɛ-lysine/gellan gum hydrogels for potential corneal constructs. Materials Science and Engineering: C, 131, 112476. doi:10.1016/j.msec.2021.112476

DOI: 10.1016/j.msec.2021.112476

Biological tissues and components, and synthetic substrates for conjunctival cell transplantation (Journal article)

Makuloluwa, A. K., Hamill, K. J., Rauz, S., Bosworth, L., Haneef, A., Romano, V., . . . Kaye, S. B. (2021). Biological tissues and components, and synthetic substrates for conjunctival cell transplantation. OCULAR SURFACE, 22, 15-26. doi:10.1016/j.jtos.2021.06.003

DOI: 10.1016/j.jtos.2021.06.003

Characterization of Tunable Poly-ε-Lysine-Based Hydrogels for Corneal Tissue Engineering. (Journal article)

Lace, R., Duffy, G. L., Gallagher, A. G., Doherty, K. G., Maklad, O., Wellings, D. A., & Williams, R. L. (2021). Characterization of Tunable Poly-ε-Lysine-Based Hydrogels for Corneal Tissue Engineering. MACROMOLECULAR BIOSCIENCE, 21(7). doi:10.1002/mabi.202100036

DOI: 10.1002/mabi.202100036

Chemical Cross-Linking of Corneal Tissue to Reduce Progression of Loss of Sight in Patients With Keratoconus (Journal article)

Haneef, A., Gopalan, R. O. G., Rajendran, D. T., Nunes, J., Kuppamuthu, D., Radhakrishnan, N., . . . Williams, R. (2021). Chemical Cross-Linking of Corneal Tissue to Reduce Progression of Loss of Sight in Patients With Keratoconus. TRANSLATIONAL VISION SCIENCE & TECHNOLOGY, 10(5). doi:10.1167/tvst.10.5.6

DOI: 10.1167/tvst.10.5.6

Material Characterisation and Stratification of Conjunctival Epithelial Cells on Electrospun Poly(ε-Caprolactone) Fibres Loaded with Decellularised Tissue Matrices. (Journal article)

Bosworth, L. A., Doherty, K. G., Hsuan, J. D., Cray, S. P., D'Sa, R. A., Pineda Molina, C., . . . Williams, R. L. (2021). Material Characterisation and Stratification of Conjunctival Epithelial Cells on Electrospun Poly(ε-Caprolactone) Fibres Loaded with Decellularised Tissue Matrices.. Pharmaceutics, 13(3). doi:10.3390/pharmaceutics13030318

DOI: 10.3390/pharmaceutics13030318

Learning Unsupervised Parameter-Specific Affine Transformation for Medical Images Registration (Conference Paper)

Chen, X., Meng, Y., Zhao, Y., Williams, R., Vallabhaneni, S. R., & Zheng, Y. (2021). Learning Unsupervised Parameter-Specific Affine Transformation for Medical Images Registration. In MEDICAL IMAGE COMPUTING AND COMPUTER ASSISTED INTERVENTION - MICCAI 2021, PT IV Vol. 12904 (pp. 24-34). doi:10.1007/978-3-030-87202-1_3

DOI: 10.1007/978-3-030-87202-1_3

Plasma polymer surface modified expanded polytetrafluoroethylene promotes epithelial monolayer formation in vitro and can be transplanted into the dystrophic rat subretinal space (Journal article)

Nian, S., Kearns, V. R., Wong, D. S. H., Bachhuka, A., Vasilev, K., Williams, R. L., . . . Sheridan, C. M. (2021). Plasma polymer surface modified expanded polytetrafluoroethylene promotes epithelial monolayer formation in vitro and can be transplanted into the dystrophic rat subretinal space. JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE, 15(1), 49-62. doi:10.1002/term.3154

DOI: 10.1002/term.3154

2020

A human retinal microvascular endothelial-pericyte co-culture model to study diabetic retinopathy in vitro (Journal article)

Eyre, J. J., Williams, R. L., & Levis, H. J. (2020). A human retinal microvascular endothelial-pericyte co-culture model to study diabetic retinopathy in vitro. EXPERIMENTAL EYE RESEARCH, 201. doi:10.1016/j.exer.2020.108293

DOI: 10.1016/j.exer.2020.108293

Exploratory use of fluorescent SmartProbes for the rapid detection of microbial isolates causing corneal ulcer. (Journal article)

Gunasekaran, R., Lalitha, P., Megia-Fernandez, A., Bradley, M., Williams, R. L., Dhaliwal, K., . . . Mills, B. (n.d.). Exploratory use of fluorescent SmartProbes for the rapid detection of microbial isolates causing corneal ulcer.. American journal of ophthalmology. doi:10.1016/j.ajo.2020.06.014

DOI: 10.1016/j.ajo.2020.06.014

Poly-ε-Lysine or Mel4 Antimicrobial Surface Modification on a Novel Peptide Hydrogel Bandage Contact Lens (Journal article)

Lace, R., Doherty, K., Dutta, D., Willcox, M., & Williams, R. (n.d.). Poly-ε-Lysine or Mel4 Antimicrobial Surface Modification on a Novel Peptide Hydrogel Bandage Contact Lens. Advanced Materials Interfaces. doi:10.1002/admi.202001232

DOI: 10.1002/admi.202001232

Antimicrobial Activity of Poly-epsilon-lysine Peptide Hydrogels Against Pseudomonas aeruginosa (Journal article)

Kennedy, S. M., Deshpande, P., Gallagher, A. G., Horsburgh, M. J., Allison, H. E., Kaye, S. B., . . . Williams, R. L. (2020). Antimicrobial Activity of Poly-epsilon-lysine Peptide Hydrogels Against Pseudomonas aeruginosa. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 61(10). doi:10.1167/iovs.61.10.18

DOI: 10.1167/iovs.61.10.18

In vitro and computational modelling of drug delivery across the outer blood-retinal barrier (Journal article)

Davies, A. E., Williams, R. L., Lugano, G., Pop, S. R., & Kearns, V. R. (2020). In vitro and computational modelling of drug delivery across the outer blood-retinal barrier. INTERFACE FOCUS, 10(2). doi:10.1098/rsfs.2019.0132

DOI: 10.1098/rsfs.2019.0132

Mass Spectrometry Reveals α-2-HS-Glycoprotein as a Key Early Extracellular Matrix Protein for Conjunctival Cells (Journal article)

Makuloluwa, A. K., Stewart, R. M. K., Kaye, S. B., Williams, R. L., & Hamill, K. J. (2020). Mass Spectrometry Reveals α-2-HS-Glycoprotein as a Key Early Extracellular Matrix Protein for Conjunctival Cells. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 61(3). doi:10.1167/iovs.61.3.44

DOI: 10.1167/iovs.61.3.44

CRISPR-Cas9-mediated labelling of the C-terminus of human laminin β1 leads to secretion inhibition (Journal article)

Shaw, L., Williams, R. L., & Hamill, K. J. (2020). CRISPR-Cas9-mediated labelling of the C-terminus of human laminin β1 leads to secretion inhibition. BMC RESEARCH NOTES, 13(1). doi:10.1186/s13104-020-04956-z

DOI: 10.1186/s13104-020-04956-z

Ophthalmic Biomaterials (Chapter)

Williams, R. L., & Wong, D. (2021). Ophthalmic Biomaterials. In Biomedical Materials (pp. 495-515). Springer International Publishing. doi:10.1007/978-3-030-49206-9_15

DOI: 10.1007/978-3-030-49206-9_15

2019

Proof on Concept: Semi-Automated Alignment of Evar Surveillance Radiographs – Increasing the Sensitivity to Device Migration and Distortion (Journal article)

Roy, I., Zheng, Y., Czanner, G., Williams, R., & Vallabhaneni, S. R. (2019). Proof on Concept: Semi-Automated Alignment of Evar Surveillance Radiographs – Increasing the Sensitivity to Device Migration and Distortion. European Journal of Vascular and Endovascular Surgery, 58(6), e109. doi:10.1016/j.ejvs.2019.06.646

DOI: 10.1016/j.ejvs.2019.06.646

Antimicrobial nitric oxide releasing contact lens gels for the treatment of microbial keratitis. (Journal article)

Aveyard, J. L., Deller, R. C., Lace, R., Williams, R. L., Kaye, S. B., Kolegraff, K. N., . . . D'Sa, R. A. (2019). Antimicrobial nitric oxide releasing contact lens gels for the treatment of microbial keratitis.. ACS applied materials & interfaces. doi:10.1021/acsami.9b13958

DOI: 10.1021/acsami.9b13958

Poly-ε-lysine based hydrogels as synthetic substrates for the expansion of corneal endothelial cells for transplantation (Journal article)

Kennedy, S., Lace, R., Carserides, C., Gallagher, A. G., Wellings, D. A., Williams, R. L., & Levis, H. J. (2019). Poly-ε-lysine based hydrogels as synthetic substrates for the expansion of corneal endothelial cells for transplantation. JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 30(9). doi:10.1007/s10856-019-6303-1

DOI: 10.1007/s10856-019-6303-1

Plasma Polymer Coatings To Direct the Differentiation of Mouse Kidney-Derived Stem Cells into Podocyte and Proximal Tubule-like Cells (Journal article)

Hopp, I., MacGregor, M. N., Doherty, K., Visalakshan, R. M., Vasilev, K., Williams, R., & Murray, P. (2019). Plasma Polymer Coatings To Direct the Differentiation of Mouse Kidney-Derived Stem Cells into Podocyte and Proximal Tubule-like Cells. ACS Biomaterials Science and Engineering, 5(6), 2834-2845. doi:10.1021/acsbiomaterials.9b00299

DOI: 10.1021/acsbiomaterials.9b00299

Learning Active Contour Models for Medical Image Segmentation (Conference Paper)

Chen, X., Williams, B. M., Vallabhaneni, S. R., Czanner, G., Williams, R., & Zheng, Y. (2019). Learning Active Contour Models for Medical Image Segmentation. In 2019 IEEE/CVF Conference on Computer Vision and Pattern Recognition (CVPR) (pp. 11624-11632). Long Beach, CA, USA: IEEE. doi:10.1109/cvpr.2019.01190

DOI: 10.1109/cvpr.2019.01190

Plasma Polymerisation Using Helium Atmospheric-Pressure Plasma Jet with Heptylamine Monomer (Journal article)

Doherty, K. G., Oh, J. -S., Unsworth, P., Sheridan, C. M., Weightman, P., Bradley, J., & Williams, R. L. (2019). Plasma Polymerisation Using Helium Atmospheric-Pressure Plasma Jet with Heptylamine Monomer. Plasma Processes and Polymers, 16(4). doi:10.1002/ppap.201800185

DOI: 10.1002/ppap.201800185

Cover Picture: Plasma Process. Polym. 4/2019 (Journal article)

Doherty, K. G., Oh, J., Unsworth, P., Sheridan, C. M., Weightman, P., Bradley, J. W., & Williams, R. L. (2019). Cover Picture: Plasma Process. Polym. 4/2019. Plasma Processes and Polymers, 16(4). doi:10.1002/ppap.201970009

DOI: 10.1002/ppap.201970009

Biomaterials in Ophthalmology (Chapter)

Williams, R. L., Levis, H. J., Lace, R., Doherty, K. G., Kennedy, S. M., & Kearns, V. R. (2019). Biomaterials in Ophthalmology. In ENCYCLOPEDIA OF BIOMEDICAL ENGINEERING, VOL 1 (pp. 289-300). doi:10.1016/B978-0-12-801238-3.11034-7

DOI: 10.1016/B978-0-12-801238-3.11034-7

INCORPORATION OF ENDOTHELIAL COLONY FORMING CELLS INTO AN IN VITRO HUMAN PRIMARY CO-CULTURE MODEL OF DIABETIC RETINOPATHY (Conference Paper)

Eyre, J. J., Bosworth, L. A., Williams, R. L., & Levis, H. J. (2019). INCORPORATION OF ENDOTHELIAL COLONY FORMING CELLS INTO AN IN VITRO HUMAN PRIMARY CO-CULTURE MODEL OF DIABETIC RETINOPATHY. In EUROPEAN JOURNAL OF OPHTHALMOLOGY Vol. 29 (pp. NP21-NP22). Retrieved from https://www.webofscience.com/

Laminin β1 with C-terminal Dendra2 fluorescent protein tag is inefficiently secreted from lung adenocarcinoma cells in culture (Conference Paper)

Shaw, L., Williams, R. L., & Hamill, K. J. (2019). Laminin β1 with C-terminal Dendra2 fluorescent protein tag is inefficiently secreted from lung adenocarcinoma cells in culture. In INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY Vol. 100 (pp. A35). Retrieved from https://www.webofscience.com/

Learning Active Contour Models for Medical Image Segmentation. (Conference Paper)

Chen, X., Williams, B. M., Vallabhaneni, S. R., Czanner, G., Williams, R., & Zheng, Y. (2019). Learning Active Contour Models for Medical Image Segmentation.. In CVPR (pp. 11632-11640). Computer Vision Foundation / IEEE.

2018

Biomaterials for Regenerative Medicine Approaches for the Anterior Segment of the Eye (Journal article)

Williams, R., Lace, R., Kennedy, S., Doherty, K., & Levis, H. (2018). Biomaterials for Regenerative Medicine Approaches for the Anterior Segment of the Eye. ADVANCED HEALTHCARE MATERIALS, 7(10). doi:10.1002/adhm.201701328

DOI: 10.1002/adhm.201701328

Developing Regenerative Medicine Strategies for Diabetic Retinopathy using Human Retinal Endothelial Cells (Conference Paper)

Eyre, J. J., Williams, R. L., Bosworth, L. A., & Levis, H. J. (2018). Developing Regenerative Medicine Strategies for Diabetic Retinopathy using Human Retinal Endothelial Cells. In EUROPEAN JOURNAL OF OPHTHALMOLOGY Vol. 28 (pp. 12). Retrieved from https://www.webofscience.com/

Modulated release from implantable ocular silicone oil tamponade drug reservoirs (Journal article)

Cauldbeck, H., Le Hellaye, M., McDonald, T., Long, M., Williams, R., Rannard, S. P., & Kearns, V. R. (2018). Modulated release from implantable ocular silicone oil tamponade drug reservoirs. Journal of Polymer Science. Part A, Polymer Chemistry, 56(8), 938-946. doi:10.1002/pola.28973

DOI: 10.1002/pola.28973

Development of decellularized conjunctiva as a substrate for the ex vivo expansion of conjunctival epithelium (Journal article)

Kasbekar, S., Kaye, S. B., Williams, R. L., Stewart, R. M. K., Leow-Dyke, S., & Rooney, P. (2018). Development of decellularized conjunctiva as a substrate for the ex vivo expansion of conjunctival epithelium. JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE, 12(2), E973-E982. doi:10.1002/term.2419

DOI: 10.1002/term.2419

2017

The Role of Controlled Surface Topography and Chemistry on Mouse Embryonic Stem Cell Attachment, Growth and Self-Renewal (Journal article)

Macgregor, M., Williams, R., Downes, J., Bachhuka, A., & Vasilev, K. (2017). The Role of Controlled Surface Topography and Chemistry on Mouse Embryonic Stem Cell Attachment, Growth and Self-Renewal. MATERIALS, 10(9). doi:10.3390/ma10091081

DOI: 10.3390/ma10091081

Development of a Poly-epsilon-lysine Contact Lens for Drug Delivery in the Management of Fungal Keratitis (Conference Paper)

McLean, K., Gallagher, A. G., Stewart, R. M. K., Wellings, D. A., Allison, H. E., & Williams, R. (2017). Development of a Poly-epsilon-lysine Contact Lens for Drug Delivery in the Management of Fungal Keratitis. In INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Vol. 58. Retrieved from http://gateway.webofknowledge.com/

Development of a Poly-ε-lysine Contact Lens as a Drug Delivery Device for the Treatment of Fungal Keratitis (Journal article)

Gallagher, A. G., McLean, K., Stewart, R. M. K., Wellings, D., Allison, H. E., & Williams, R. L. (2017). Development of a Poly-ε-lysine Contact Lens as a Drug Delivery Device for the Treatment of Fungal Keratitis. Investigative Ophthalmology and Visual Science, 58(11), 4499-4505. doi:10.1167/iovs.17-22301

DOI: 10.1167/iovs.17-22301

The formation of a functional retinal pigment epithelium occurs on porous polytetrafluoroethylene substrates independently of the surface chemistry (Journal article)

Kearns, V. R., Tasker, J., Zhuola., Akhtar, R., Bachhuka, A., Vasilev, K., . . . Williams, R. (2017). The formation of a functional retinal pigment epithelium occurs on porous polytetrafluoroethylene substrates independently of the surface chemistry. Journal of Materials Science: Materials in Medicine, 28. doi:10.1007/s10856-017-5926-3

DOI: 10.1007/s10856-017-5926-3

Towards better characterization and quantification of emulsification of silicone oil in vitro (Journal article)

Chan, Y. K., Czanner, G., Shum, H. C., Williams, R. L., Cheung, N., & Wong, D. (2017). Towards better characterization and quantification of emulsification of silicone oil in vitro. Acta Ophthalmologica, 95(5), e385-e392. doi:10.1111/aos.13258

DOI: 10.1111/aos.13258

2016

Controlling drug release from non-aqueous environments: Moderating delivery from ocular silicone oil drug reservoirs to combat proliferative vitreoretinopathy (Journal article)

Cauldbeck, H., Le Hellaye, M., Long, M., Kennedy, S. M., Williams, R. L., Kearns, V. R., & Rannard, S. P. (2016). Controlling drug release from non-aqueous environments: Moderating delivery from ocular silicone oil drug reservoirs to combat proliferative vitreoretinopathy. Journal of Controlled Release, 244(Part A), 41-51. doi:10.1016/j.jconrel.2016.11.010

DOI: 10.1016/j.jconrel.2016.11.010

A Novel Peptide Hydrogel for an Antimicrobial Bandage Contact Lens (Journal article)

Gallagher, A. G., Alorabi, J. A., Wellings, D. A., Lace, R., Horsburgh, M. J., & Williams, R. L. (2016). A Novel Peptide Hydrogel for an Antimicrobial Bandage Contact Lens. Advanced Healthcare Materials, 5(16), 2013-2018. doi:10.1002/adhm.201600258

DOI: 10.1002/adhm.201600258

2015

Development of emulsification resistant heavier-than-water tamponades using high molecular weight silicone oil polymers (Journal article)

Caramoy, A., Kearns, V. R., Chan, Y. K., Hagedorn, N., Poole, R. J., Wong, D., . . . Williams, R. L. (2015). Development of emulsification resistant heavier-than-water tamponades using high molecular weight silicone oil polymers. JOURNAL OF BIOMATERIALS APPLICATIONS, 30(2), 212-220. doi:10.1177/0885328215575623

DOI: 10.1177/0885328215575623

Biomaterials for ocular reconstruction (Journal article)

Lace, R., Murray-Dunning, C., & Williams, R. (2015). Biomaterials for ocular reconstruction. JOURNAL OF MATERIALS SCIENCE, 50(4), 1523-1534. doi:10.1007/s10853-014-8707-0

DOI: 10.1007/s10853-014-8707-0

Distal fixation forces of different endovascular limb extensions in an experimental porcine model (Journal article)

Shah, S., Jones, S. M., How, T. V., Williams, R. L., & Fisher, R. K. (2015). Distal fixation forces of different endovascular limb extensions in an experimental porcine model. BRITISH JOURNAL OF SURGERY, 102, 15. Retrieved from https://www.webofscience.com/

Haemodynamic Evidence that Large Iliac Arteries Increase the Risk of Limb Migration following Endovascular Aneurysm Repair (Conference Paper)

Jones, S. M., England, A., Poole, R. J., Vallabhaneni, S. R., Brennan, J. A., McWilliams, R. G., . . . Fisher, R. K. (2015). Haemodynamic Evidence that Large Iliac Arteries Increase the Risk of Limb Migration following Endovascular Aneurysm Repair. In BRITISH JOURNAL OF SURGERY Vol. 102 (pp. 13-14). Retrieved from https://www.webofscience.com/

2014

Flow Behavior of Heavy Silicone Oil During Eye Movements (Journal article)

Chan, Y. K., Williams, R. L., & Wong, D. (2014). Flow Behavior of Heavy Silicone Oil During Eye Movements. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 55(12), 8453-8457. doi:10.1167/iovs.14-15439

DOI: 10.1167/iovs.14-15439

Fibrinogen adsorption and platelet adhesion to silica surfaces with stochastic nanotopography (Journal article)

Lord, M. S., Whitelock, J. M., Simmons, A., Williams, R. L., & Milthorpe, B. K. (2014). Fibrinogen adsorption and platelet adhesion to silica surfaces with stochastic nanotopography. BIOINTERPHASES, 9(4). doi:10.1116/1.4900993

DOI: 10.1116/1.4900993

Computational Fluid Dynamic (CFD) analysis of the distraction forces experienced by stent-grafts following fEVAR (Conference Paper)

Jones, S. M., Poole, R. J., How, T. V., Williams, R. L., McWilliams, R. G., Brennan, J. A., . . . Fisher, R. K. (2014). Computational Fluid Dynamic (CFD) analysis of the distraction forces experienced by stent-grafts following fEVAR. In BRITISH JOURNAL OF SURGERY Vol. 101 (pp. 2). Retrieved from https://www.webofscience.com/

Computational fluid dynamic analysis of the effect of morphologic features on distraction forces in fenestrated stent grafts (Journal article)

Jones, S. M., Poole, R. J., How, T. V., Williams, R. L., McWilliams, R. G., Brennan, J. A., . . . Fisher, R. K. (2014). Computational fluid dynamic analysis of the effect of morphologic features on distraction forces in fenestrated stent grafts. JOURNAL OF VASCULAR SURGERY, 60(6), 1648-U632. doi:10.1016/j.jvs.2014.08.077

DOI: 10.1016/j.jvs.2014.08.077

2013

Novel Heavy Tamponade for Vitreoretinal Surgery (Journal article)

Williams, R. L., Kearns, V. R., Lo, A. C., Day, M., Garvey, M. J., Krishna, Y., . . . Wong, D. (2013). Novel Heavy Tamponade for Vitreoretinal Surgery. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 54(12), 7284-7292. doi:10.1167/iovs.13-11876

DOI: 10.1167/iovs.13-11876

Polystyrene Surface Modification for Localized Cell Culture Using a Capillary Dielectric Barrier Discharge Atmospheric-Pressure Microplasma Jet (Journal article)

Doherty, K. G., Oh, J. -S., Unsworth, P., Bowfield, A., Sheridan, C. M., Weightman, P., . . . Williams, R. L. (2013). Polystyrene Surface Modification for Localized Cell Culture Using a Capillary Dielectric Barrier Discharge Atmospheric-Pressure Microplasma Jet. PLASMA PROCESSES AND POLYMERS, 10(11), 978-989. doi:10.1002/ppap.201300052

DOI: 10.1002/ppap.201300052

Characterization of the interface between adsorbed fibronectin and human embryonic stem cells (Journal article)

Kalaskar, D. M., Downes, J. E., Murray, P., Edgar, D. H., & Williams, R. L. (2013). Characterization of the interface between adsorbed fibronectin and human embryonic stem cells. JOURNAL OF THE ROYAL SOCIETY INTERFACE, 10(83). doi:10.1098/rsif.2013.0139

DOI: 10.1098/rsif.2013.0139

Complications related to the tamponade agent: Emulsification of tamponade agents (Chapter)

Williams, R., & Stappler, T. (2013). Complications related to the tamponade agent: Emulsification of tamponade agents. In Complications of Vitreo-Retinal Surgery.

The influence of high intensity terahertz radiation on mammalian cell adhesion, proliferation and differentiation (Journal article)

Williams, R., Schofield, A., Holder, G., Downes, J., Edgar, D., Harrison, P., . . . Weightman, P. (2013). The influence of high intensity terahertz radiation on mammalian cell adhesion, proliferation and differentiation. PHYSICS IN MEDICINE AND BIOLOGY, 58(2), 373-391. doi:10.1088/0031-9155/58/2/373

DOI: 10.1088/0031-9155/58/2/373

Degradative Effects of the Biological Environment on Metals and Ceramics (Chapter)

Williams, D. F., & Williams, R. L. (2013). Degradative Effects of the Biological Environment on Metals and Ceramics. In Biomaterials Science (pp. 728-738). Elsevier. doi:10.1016/b978-0-08-087780-8.00062-0

DOI: 10.1016/b978-0-08-087780-8.00062-0

Guided gingival fibroblast attachment to titanium surfaces: an in vitro study (Journal article)

Kearns, V. R., Williams, R. L., Mirvakily, F., Doherty, P. J., & Martin, N. (2013). Guided gingival fibroblast attachment to titanium surfaces: an in vitro study. JOURNAL OF CLINICAL PERIODONTOLOGY, 40(1), 99-108. doi:10.1111/jcpe.12025

DOI: 10.1111/jcpe.12025

Induction of mesenchymal stem cell chondrogenesis by polyacrylate substrates (Journal article)

Glennon-Alty, L., Williams, R., Dixon, S., & Murray, P. (2013). Induction of mesenchymal stem cell chondrogenesis by polyacrylate substrates. ACTA BIOMATERIALIA, 9(4), 6041-6051. doi:10.1016/j.actbio.2012.12.007

DOI: 10.1016/j.actbio.2012.12.007

2012

Plasma polymer coatings to aid retinal pigment epithelial growth for transplantation in the treatment of age related macular degeneration (Journal article)

Kearns, V., Mistry, A., Mason, S., Krishna, Y., Sheridan, C., Short, R., & Williams, R. L. (2012). Plasma polymer coatings to aid retinal pigment epithelial growth for transplantation in the treatment of age related macular degeneration. JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 23(8), 2013-2021. doi:10.1007/s10856-012-4675-6

DOI: 10.1007/s10856-012-4675-6

Characteristics Of Rat Iris Pigment Epithelial Cells Cultured On Modified Expanded-polytetrafluroethylene (ePTFE) Substrates (Conference Paper)

Nian, S., Sheridan, C. M., Kearns, V., Williams, R., Wong, D., Vasillev, K., . . . Lai, W. W. (2012). Characteristics Of Rat Iris Pigment Epithelial Cells Cultured On Modified Expanded-polytetrafluroethylene (ePTFE) Substrates. In ARVO 2012 Vol. 53 (pp. 5840). Fort Lauderdale: IOVS.

GROWTH OF PORCINE IRIS PIGMENTED EPITHELIAL CELLS ON SUBSTRATES FOR THE TREATMENT OF AGE RELATED MACULAR DEGENERATION (AMD) (Conference Paper)

Alias, E., Kearns, V., Harrison, I., Sheridan, C., & Williams, R. (2012). GROWTH OF PORCINE IRIS PIGMENTED EPITHELIAL CELLS ON SUBSTRATES FOR THE TREATMENT OF AGE RELATED MACULAR DEGENERATION (AMD). In XX Biennial Meeting of the International Society for Eye Research (pp. 261). Berlin: ISER. Retrieved from http://www.iser.org/files/2012_abstracts.pdf

QUANTIFICATION OF RETINAL THICKNESS FOLLOWING IMPLANTATION OF ACELLULAR SURFACE-MODIFIED EXPANDED POLYTETRAFLUOROETHYLENE (EPTFE) IN A RABBIT MODEL USING SD-OCT AND HISTOLOGY (Conference Paper)

Kearns, V., Eter, N., Liu, Z., Brinken, R., Somboonthanakij, S., Wongsawag, W., . . . Stanzel, B. V. (2012). QUANTIFICATION OF RETINAL THICKNESS FOLLOWING IMPLANTATION OF ACELLULAR SURFACE-MODIFIED EXPANDED POLYTETRAFLUOROETHYLENE (EPTFE) IN A RABBIT MODEL USING SD-OCT AND HISTOLOGY. In XX Biennial Meeting of the International Society for Eye Research (pp. 287). Berlin: ISER. Retrieved from http://www.iser.org/files/2012_abstracts.pdf

QUANTIFICATION OF RETINAL THICKNESS FOLLOWING IMPLANTATION OF ACELLULAR ULTRATHIN POLYESTER CELL CARRIERS IN A RABBIT MODEL USING SD-OCT AND HISTOLOGY (Conference Paper)

Stanzel, B., Kearns, V., Eter, N., Liu, Z., Brinken, R., Somboonthanakij, S., . . . Sheridan, C. (2012). QUANTIFICATION OF RETINAL THICKNESS FOLLOWING IMPLANTATION OF ACELLULAR ULTRATHIN POLYESTER CELL CARRIERS IN A RABBIT MODEL USING SD-OCT AND HISTOLOGY. In XX Biennial Meeting of the International Society for Eye Research (pp. 266). Berlin: ISER. Retrieved from http://www.iser.org/files/2012_abstracts.pdf

2011

Emulsification of Silicone Oil and Eye Movements (Journal article)

Chan, Y. K., Ng, C. O., Knox, P. C., Garvey, M. J., Williams, R. L., & Wong, D. (2011). Emulsification of Silicone Oil and Eye Movements. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 52(13), 9721-9727. doi:10.1167/iovs.11-8586

DOI: 10.1167/iovs.11-8586

Atmospheric pressure micro-plasma jet technology for influencing cell-surface interactions (Conference Paper)

Doherty, K., Oh, J. S., Sheridan, C., Williams, R., & Bradley, J. W. (2011). Atmospheric pressure micro-plasma jet technology for influencing cell-surface interactions. In 24th European Conference on Biomaterials - Annual Conference of the European Society for Biomaterials.

Glycosaminoglycan coatings for intraocular lenses as a potential to inhibit posterior capsule opacification (Conference Paper)

Lace, R., Rhodes, A., Onis, S., Sandhu, S., Luthra, A., Sheridan, C., & Williams, R. (2011). Glycosaminoglycan coatings for intraocular lenses as a potential to inhibit posterior capsule opacification. In 24th European Conference on Biomaterials - Annual Conference of the European Society for Biomaterials.

The influence of surface chemistry and roughness on ECM production on bruch's membrane prostheses (Conference Paper)

Kearns, V., Vasilev, K., Sheridan, C., & Williams, R. (2011). The influence of surface chemistry and roughness on ECM production on bruch's membrane prostheses. In 24th European Conference on Biomaterials - Annual Conference of the European Society for Biomaterials.

The status of the alice r&d facility at stfc daresbury laboratory (Conference Paper)

Jackson, F., Angal-Kalinin, D., Bate, B., Buckley, R., Buckley, S., Clarke, J., . . . Wolski, A. (2011). The status of the alice r&d facility at stfc daresbury laboratory. In IPAC 2011 - 2nd International Particle Accelerator Conference (pp. 934-936).

Ocular epithelial transplantation: current uses and future potential (Journal article)

Mason, S. L., Stewart, R. M. K., Kearns, V. R., Williams, R. L., & Sheridan, C. M. (2011). Ocular epithelial transplantation: current uses and future potential. REGENERATIVE MEDICINE, 6(6), 767-782. doi:10.2217/RME.11.94

DOI: 10.2217/RME.11.94

The use of reflection anisotropy spectroscopy to assess the alignment of collagen (Journal article)

Schofield, A. L., Smith, C. I., Kearns, V. R., Martin, D. S., Farrell, T., Weightman, P., & Williams, R. L. (2011). The use of reflection anisotropy spectroscopy to assess the alignment of collagen. JOURNAL OF PHYSICS D-APPLIED PHYSICS, 44(33). doi:10.1088/0022-3727/44/33/335302

DOI: 10.1088/0022-3727/44/33/335302

Culture of Iris Pigment Epithelial Cells on Expanded-polytetrafluroethylene (ePTFE) Substrates for the Treatment of Age-related Macular Degeneration (Conference Paper)

Nian, S., Lo, A. C. Y., Sheridan, C., Williams, R. L., Wong, D., Vasilev, K., & Lai, W. W. (2011). Culture of Iris Pigment Epithelial Cells on Expanded-polytetrafluroethylene (ePTFE) Substrates for the Treatment of Age-related Macular Degeneration. In I-PERCEPTION Vol. 2 (pp. 306). Retrieved from https://www.webofscience.com/

The impact of axial length on retinal tamponade for gas, silicone oil, and heavy silicone oil, using an in vitro model (Journal article)

Hillier, R. J., Stappler, T., Williams, R. L., Turner, G. S., & Wong, D. (2011). The impact of axial length on retinal tamponade for gas, silicone oil, and heavy silicone oil, using an in vitro model. GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 249(5), 671-675. doi:10.1007/s00417-010-1579-3

DOI: 10.1007/s00417-010-1579-3

Expanded polytetrafluoroethylene as a substrate for retinal pigment epithelial cell growth and transplantation in age-related macular degeneration (Journal article)

Krishna, Y., Sheridan, C., Kent, D., Kearns, V., Grierson, I., & Williams, R. (2011). Expanded polytetrafluoroethylene as a substrate for retinal pigment epithelial cell growth and transplantation in age-related macular degeneration. BRITISH JOURNAL OF OPHTHALMOLOGY, 95(4), 569-573. doi:10.1136/bjo.2009.169953

DOI: 10.1136/bjo.2009.169953

Injectability of silicone oil-based tamponade agents (Journal article)

Williams, R. L., Day, M. J., Garvey, M. J., Morphis, G., Irigoyen, C., Wong, D., & Stappler, T. (2011). Injectability of silicone oil-based tamponade agents. BRITISH JOURNAL OF OPHTHALMOLOGY, 95(2), 273-276. doi:10.1136/bjo.2010.192344

DOI: 10.1136/bjo.2010.192344

Comparison of Growth and Monolayer Formation of Primary Bovine Rpe and Ipe on Polyurethane (Pu) Membranes. (Conference Paper)

Alias, E., Kearns, V. R., Harrison, I. M., Sheridan, C. M., & Williams, R. L. (2011). Comparison of Growth and Monolayer Formation of Primary Bovine Rpe and Ipe on Polyurethane (Pu) Membranes.. In TERMIS-EU (pp. 342). .: TERMIS.

Contributor contact details (Chapter)

Williams, R., Szili, E., Short, R., Steele, D., Bradley, J., Rhodes, A., . . . Sammons, R. L. (2011). Contributor contact details. In Surface Modification of Biomaterials (pp. xi-xiv). Elsevier. doi:10.1016/b978-1-84569-640-5.50018-x

DOI: 10.1016/b978-1-84569-640-5.50018-x

Optimisation of primary cell culture conditions for retinal and iris pigment epithelial cell transplantation on artificial substrates (Conference Paper)

Kearns, V., Vasilev, K., Nian, S., Sheridan, C., & Williams, R. L. (2011). Optimisation of primary cell culture conditions for retinal and iris pigment epithelial cell transplantation on artificial substrates. In TERMIS-EU (pp. .). Granada, Spain: TERMIS.

Preface (Book)

Williams, R. (2011). Preface. Elsevier. doi:10.1016/b978-1-84569-640-5.50019-1

DOI: 10.1016/b978-1-84569-640-5.50019-1

Preface (Chapter)

Williams, R. (2011). Preface. In Surface Modification of Biomaterials (pp. xv-xvi). Elsevier. doi:10.1016/b978-1-84569-640-5.50019-1

DOI: 10.1016/b978-1-84569-640-5.50019-1

Surface Modification of Biomaterials: Methods, Analysis and Applications (Book)

Surface Modification of Biomaterials: Methods, Analysis and Applications (2010). . Retrieved from https://www.webofscience.com/

Surface Modification of biomaterials; Methods, analysis and applications (Book)

Williams, R. (Ed.) (2011). Surface Modification of biomaterials; Methods, analysis and applications. Cambridge: Woodhead Publishing Ltd.

Surface modified expanded-polytetrafluoroethylene (ePTFE) substrates for retinal pigment epithelial growth and implantation (Journal article)

Kearns, V. R., Nian, S., Vasilev, K., Sheridan, C., & Williams, R. L. (2011). Surface modified expanded-polytetrafluoroethylene (ePTFE) substrates for retinal pigment epithelial growth and implantation. European Cells and Materials, 22(SUPPL.2), 54.

2010

Recent developments on ALICE (Accelerators and lasers in combined experiments) at Daresbury Laboratory (Conference Paper)

Saveliev, Y., Bate, B., Buckley, R., Buckley, S., Clarke, J., Corlett, P., . . . Powers, T. (2010). Recent developments on ALICE (Accelerators and lasers in combined experiments) at Daresbury Laboratory. In IPAC 2010 - 1st International Particle Accelerator Conference (pp. 2350-2352).

The Terahertz Beamline and Tissue Culture Facility on the Alice Accelerator at the Daresbury Laboratory (Journal article)

Weightman, P., Holder, G., Schofield, A., Williams, R. L., Harrison, P., Bowfield, A., & Surman, M. (2010). The Terahertz Beamline and Tissue Culture Facility on the Alice Accelerator at the Daresbury Laboratory. Siberian Journal of Physics, 5(4), 28-31. doi:10.54362/1818-7919-2010-5-4-28-31

DOI: 10.54362/1818-7919-2010-5-4-28-31

Friction transfer of polytetrafluoroethylene (PTFE) to produce nanoscale features and influence cellular response in vitro (Journal article)

Kearns, V. R., Doherty, P. J., Beamson, G., Martin, N., & Williams, R. L. (2010). Friction transfer of polytetrafluoroethylene (PTFE) to produce nanoscale features and influence cellular response in vitro. JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 21(7), 2213-2226. doi:10.1007/s10856-010-4081-x

DOI: 10.1007/s10856-010-4081-x

Reflection anisotropy spectra of polydimethylsiloxane under a range of mechanically applied stress (Journal article)

Farrell, T., Smith, C. I., Schofield, A. L., Williams, R. L., & Weightman, P. (2010). Reflection anisotropy spectra of polydimethylsiloxane under a range of mechanically applied stress. JOURNAL OF PHYSICS D-APPLIED PHYSICS, 43(24). doi:10.1088/0022-3727/43/24/245301

DOI: 10.1088/0022-3727/43/24/245301

MECHANICAL AND BIOLOGICAL PROPERTIES OF TITANIUM SYNTACTIC FOAMS (Conference Paper)

Xue, X. B., Zhao, Y. Y., Kearns, V., & Williams, R. L. (2010). MECHANICAL AND BIOLOGICAL PROPERTIES OF TITANIUM SYNTACTIC FOAMS. In TMS 2010 139TH ANNUAL MEETING & EXHIBITION - SUPPLEMENTAL PROCEEDINGS, VOL 2: MATERIALS CHARACTERIZATION, COMPUTATION AND MODELING AND ENERGY (pp. 129-+). Retrieved from https://www.webofscience.com/

F4H5: a novel substance for the removal of silicone oil from intraocular lenses (Journal article)

Stappler, T., Williams, R., & Wong, D. (2010). F4H5: a novel substance for the removal of silicone oil from intraocular lenses. BRITISH JOURNAL OF OPHTHALMOLOGY, 94(3), 364-367. doi:10.1136/bjo.2009.161489

DOI: 10.1136/bjo.2009.161489

INCREASING THE EXTENSIONAL VISCOSITY OF SILICONE OIL REDUCES THE TENDENCY FOR EMULSIFICATION (Journal article)

Williams, R. L., Day, M., Garvey, M. J., English, R., & Wong, D. (2010). INCREASING THE EXTENSIONAL VISCOSITY OF SILICONE OIL REDUCES THE TENDENCY FOR EMULSIFICATION. RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES, 30(2), 300-304. doi:10.1097/IAE.0b013e3181babe0c

DOI: 10.1097/IAE.0b013e3181babe0c

13 Drug–device combination products for ocular applications (Chapter)

Williams, R. L., & Kearns, V. R. (2010). 13 Drug–device combination products for ocular applications. In Drug-Device Combination Products (pp. 311-338). Elsevier. doi:10.1533/9781845697488.2.311

DOI: 10.1533/9781845697488.2.311

Atmospheric-Pressure Microplasma-Jet Modified Polystyrene Surfaces as Substrates for Epithelial Cell Growth (Journal article)

Oh, J. S., Bradley, J. W., Doherty, K. G., Sheridan, C. M., Williams, R. L., Bowfield, A., . . . Weightman, P. (2010). Atmospheric-Pressure Microplasma-Jet Modified Polystyrene Surfaces as Substrates for Epithelial Cell Growth. AVS 57th International Symposium and Exhibition, 57, PS2-MoA11. Retrieved from http://www2.avs.org/symposium2010/Papers/Paper_PS2-MoA11.html

Comparison of growth and monolayer formation of primary bovine RPE and IPE on polyurethane (PU) membranes (Conference Paper)

Alias, E., Kearns, V. R., Harrison, I. M., Dixon, S. A., Laws, F. A., Sheridan, C. M., & Williams, R. L. (2010). Comparison of growth and monolayer formation of primary bovine RPE and IPE on polyurethane (PU) membranes. In TERMIS-EU (pp. x). Galway, Ireland: TERMIS.

Effect of VEGF and Anti-VEGF Compounds on Retinal Pigment Epithelium Permeability: An in vitro Study (Conference Paper)

Campa, C., Kearns, V., Sheridan, C., Williams, R., Grierson, I., & Harding, S. P. (2010). Effect of VEGF and Anti-VEGF Compounds on Retinal Pigment Epithelium Permeability: An in vitro Study. In INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Vol. 51. Retrieved from https://www.webofscience.com/

Evaluation of Basement Membrane Formation on Bruch's Membrane Implants (Conference Paper)

Kearns, V. R., Vasilev, K., Sheridan, C. M., & Williams, R. L. (2010). Evaluation of Basement Membrane Formation on Bruch's Membrane Implants. In TERMIS-EU (pp. x). Galway, Ireland: TERMIS.

Novel Polymeric Coatings with the Potential to Control In-stent Restenosis - An In Vitro Study (Journal article)

Nickson, C. M., Doherty, P. J., & Williams, R. L. (2010). Novel Polymeric Coatings with the Potential to Control In-stent Restenosis - An In Vitro Study. JOURNAL OF BIOMATERIALS APPLICATIONS, 24(5), 437-452. doi:10.1177/0885328208099338

DOI: 10.1177/0885328208099338

Surface Modified Expanded-polytetrafluoroethylene (ePTFE) Substrates for Retinal Pigment Epithelial Growth and Implantation (Conference Paper)

Kearns, V. R., Nian, S., Vasilev, K., Sheridan, C. M., & Williams, R. L. (2010). Surface Modified Expanded-polytetrafluoroethylene (ePTFE) Substrates for Retinal Pigment Epithelial Growth and Implantation. In TCES (Tissue and Cell Engineering Society) 2010 (pp. x). Manchester, UK: TCES.

2009

Ophthalmic Biomaterials (Chapter)

Williams, R. L., & Wong, D. (2009). Ophthalmic Biomaterials. In BIOMEDICAL MATERIALS (pp. 327-347). doi:10.1007/978-0-387-84872-3_12

DOI: 10.1007/978-0-387-84872-3_12

Drug delivery systems for the eye (Journal article)

Kearns, V. R., & Williams, R. L. (2009). Drug delivery systems for the eye. EXPERT REVIEW OF MEDICAL DEVICES, 6(3), 277-290. doi:10.1586/ERD.09.4

DOI: 10.1586/ERD.09.4

Angle resolved XPS characterization of cationic polyacrylamides (Journal article)

Zekonyte, J., Williams, R. L., Beamson, G., & Weightman, P. (2009). Angle resolved XPS characterization of cationic polyacrylamides. SURFACE AND INTERFACE ANALYSIS, 41(4), 316-323. doi:10.1002/sia.3025

DOI: 10.1002/sia.3025

Drug-Device Combination Products for Ocular Applications (Chapter)

Williams, R. L., & Kearns, V. R. (2009). Drug-Device Combination Products for Ocular Applications. In A. Lewis (Ed.), Drug Device Combination Products (pp. In Press). Cambridge, UK: Woodhead Publishing Limited.

Drug-device combination products for ocular applications (Chapter)

Williams, R. L., & Kearns, V. R. (2009). Drug-device combination products for ocular applications. In DRUG DEVICE COMBINATION PRODUCTS (pp. 311-338). Retrieved from https://www.webofscience.com/

Replacement of the RPE monolayer (Journal article)

Sheridan, C. M., Mason, S., Pattwell, D. M., Kent, D., Grierson, I., & Williams, R. (2009). Replacement of the RPE monolayer. EYE, 23(10), 1910-1915. doi:10.1038/eye.2008.420

DOI: 10.1038/eye.2008.420

•Calcium depletion alters tenocyte surface adhesion ability: possible role of ca2+ channel blockers in tendon healing. (Journal article)

Kamarul, T., Roebuck, M. M., Williams, R. L., & Frostick, S. P. (2009). •Calcium depletion alters tenocyte surface adhesion ability: possible role of ca2+ channel blockers in tendon healing.. British J Orthopaedics, 2010, i-ii.

•Tenocyte alignment is dependant upon cell density and tensional loading. (Journal article)

Kamarul, T., Roebuck, M. M., Williams, R. L., & Frostick, S. P. (2009). •Tenocyte alignment is dependant upon cell density and tensional loading.. European Cell and Materials Journal, 2010, i-ii.

•The effects of cyclical loading on tendon fibroblast metabolism in vitro (Journal article)

Kamarul, T., Roebuck, M. M., Williams, R. L., & Frostick, S. P. (2009). •The effects of cyclical loading on tendon fibroblast metabolism in vitro. Orthopaedic Research Society, 2010, i-ii.

2008

A novel technique for probing the anisotropic structure of tendon (Conference Paper)

Smith, C. I., Mansley, C. P., Weightman, P., & Williams, R. L. (2008). A novel technique for probing the anisotropic structure of tendon. In 8th World Biomaterials Congress 2008 Vol. 3 (pp. 1233).

Human endothelial cell response to a novel polymeric stent coating (Conference Paper)

Nickson, C. M., Dixon, S., Laws, F., Harrison, I., & Williams, R. L. (2008). Human endothelial cell response to a novel polymeric stent coating. In 8th World Biomaterials Congress 2008 Vol. 4 (pp. 2155).

The effect of surface chemistry and topography on the orientation of cells and collagen (Conference Paper)

Kearns, V. R., Doherty, P. J., Martin, N., & Williams, R. L. (2008). The effect of surface chemistry and topography on the orientation of cells and collagen. In 8th World Biomaterials Congress 2008 Vol. 3 (pp. 1158).

Shear and extensional rheometry of PDMS tamponade agents used in vitroretinal surgery (Conference Paper)

Day, M., Blanchard, R. -L., English, R., Dobbie, T., Williams, R., Garvey, M., & Wong, D. (2008). Shear and extensional rheometry of PDMS tamponade agents used in vitroretinal surgery. In XVTH INTERNATIONAL CONGRESS ON RHEOLOGY - THE SOCIETY OF RHEOLOGY 80TH ANNUAL MEETING, PTS 1 AND 2 Vol. 1027 (pp. 1411-+). Retrieved from https://www.webofscience.com/

Tenocyte alignment is dependant upon cell density and tensional loading (Conference Paper)

Kamarul, T., Roebuck, M. M., Williams, R. L., & Frostick, S. P. (2008). Tenocyte alignment is dependant upon cell density and tensional loading. In European Cells and Materials Vol. 16 (pp. 62).

A guide to the removal of heavy silicone oil (Journal article)

Stappler, T., Williams, R., Gibran, S. K., Liazos, E., & Wong, D. (2008). A guide to the removal of heavy silicone oil. BRITISH JOURNAL OF OPHTHALMOLOGY, 92(6), 844-847. doi:10.1136/bjo.2007.134569

DOI: 10.1136/bjo.2007.134569

Synthesis and Properties of Functional Poly(vinylpyrrolidinone) Hydrogels for Drug Delivery (Conference Paper)

Smith, L. E., Collins, S., Liu, Z., Mac Neil, S., Williams, R., & Rimmer, S. (2008). Synthesis and Properties of Functional Poly(vinylpyrrolidinone) Hydrogels for Drug Delivery. In POLYMERS FOR BIOMEDICAL APPLICATIONS Vol. 977 (pp. 196-203). Retrieved from https://www.webofscience.com/

F4H5 -A novel substance for the removal of silicone oil from intraocular lenses. (Journal article)

Stappler, T., Williams, R., & Wong, D. (2008). F4H5 -A novel substance for the removal of silicone oil from intraocular lenses.. Invest. Ophthalmol. Vis. Sci., 49, 5602.

Manufacturing a nanometre scale surface topography with varying surface chemistry to assess the combined effect on cell behaviour (Journal article)

Cousins, B. G., Zekonyte, J., Doherty, P. J., Garvey, M. J., & Williams, R. L. (2008). Manufacturing a nanometre scale surface topography with varying surface chemistry to assess the combined effect on cell behaviour. International Journal of Nano and Biomaterials, 1(3), 320. doi:10.1504/ijnbm.2008.016878

DOI: 10.1504/ijnbm.2008.016878

Shear and extensional rheometry of PDMS tamponade agents used in vitroretinal surgery (Journal article)

Day, M., Blanchard, R. -L., English, R., Dobbie, T., Williams, R., Garvey, M., & Wong, D. (2008). Shear and extensional rheometry of PDMS tamponade agents used in vitroretinal surgery. XVTH INTERNATIONAL CONGRESS ON RHEOLOGY - THE SOCIETY OF RHEOLOGY 80TH ANNUAL MEETING, PTS 1 AND 2, 1027, 1411-1413.

Tenocyte alignment is dependent upon cell density and tensional loading. (Journal article)

Kamarul, T., Roebuck, M. M., Williams, R. L., & Frostick, S. P. (2008). Tenocyte alignment is dependent upon cell density and tensional loading.. European Cell and Mater, 16((suppl), 62.

UK Society for Biomaterials Annual Conference: Abstracts 2008 (Book)

Williams, R. L., Kearns, V. R., & Nickson, C. M. (Eds.) (2008). UK Society for Biomaterials Annual Conference: Abstracts 2008. Liverpool, UK: UK Society for Biomaterials.

2007

Changes in the electronic structure of silicone rubber surfaces induced by oxygen plasma treatment (Journal article)

Haines, S. R., Beamson, G., Williams, R. L., & Weightman, P. (2007). Changes in the electronic structure of silicone rubber surfaces induced by oxygen plasma treatment. SURFACE AND INTERFACE ANALYSIS, 39(12-13), 942-947. doi:10.1002/sia.2646

DOI: 10.1002/sia.2646

Improvements in Alzheimer' Disease Diagnosis using Principal Component Analysis (PCA) in Combination with Raman Spectroscopy (Conference Paper)

Archer, J. K. J., Sudworth, C. D., Williams, R., How, T., Stone, N., Mann, D., & Black, R. A. (2007). Improvements in Alzheimer' Disease Diagnosis using Principal Component Analysis (PCA) in Combination with Raman Spectroscopy. In Diagnostic Optical Spectroscopy in Biomedicine IV. OSA. doi:10.1364/ecbo.2007.6628_37

DOI: 10.1364/ecbo.2007.6628_37

The effect of gas plasma modification on platelet and contact phase activation processes (Journal article)

Rhodes, N. P., Wilson, D. J., & Williams, R. L. (2007). The effect of gas plasma modification on platelet and contact phase activation processes. BIOMATERIALS, 28(31), 4561-4570. doi:10.1016/j.biomaterials.2007.07.008

DOI: 10.1016/j.biomaterials.2007.07.008

Improvements in Alzheimer's disease diagnosis using principal component analysis (PCA) in combination with Raman Spectroscopy (Conference Paper)

Archer, J. K. J., Sudworth, C. D., Williams, R., How, T., Stone, N., Mann, D., & Black, R. A. (2007). Improvements in Alzheimer's disease diagnosis using principal component analysis (PCA) in combination with Raman Spectroscopy. In DIAGNOSTIC OPTICAL SPECTROSCOPY IN BIOMEDICINE IV Vol. 6628. doi:10.1117/12.728464

DOI: 10.1117/12.728464

Transplantation in the treatment of age-related macular degeneration: past, present and future directions (Journal article)

Sheridan, C., Krishna, Y., Williams, R., Mason, S., Wong, D., Heimann, H., . . . Grierson, I. (2007). Transplantation in the treatment of age-related macular degeneration: past, present and future directions. Expert Review of Ophthalmology, 2(3), 497-511. doi:10.1586/17469899.2.3.497

DOI: 10.1586/17469899.2.3.497

Does the surface property of a disposable applanation tonometer account for its underestimation of intraocular pressure when compared with the Goldmann tonometer? (Journal article)

Osborne, S. F., Williams, R., Batterbury, M., & Wong, D. (2007). Does the surface property of a disposable applanation tonometer account for its underestimation of intraocular pressure when compared with the Goldmann tonometer?. GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 245(4), 555-559. doi:10.1007/s00417-006-0380-9

DOI: 10.1007/s00417-006-0380-9

Polydimethylsiloxane as a substrate for retinal pigment epithelial cell growth (Journal article)

Krishna, Y., Sheridan, C. M., Kent, D. L., Grierson, I., & Williams, R. L. (2007). Polydimethylsiloxane as a substrate for retinal pigment epithelial cell growth. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 80A(3), 669-678. doi:10.1002/jbm.a.30953

DOI: 10.1002/jbm.a.30953

Effects of a nanoparticulate silica substrate on cell attachment of Candida albicans (Journal article)

Cousins, B. G., Allison, H. E., Doherty, P. J., Edwards, C., Garvey, M. J., Martin, D. S., & Williams, R. L. (2007). Effects of a nanoparticulate silica substrate on cell attachment of Candida albicans. JOURNAL OF APPLIED MICROBIOLOGY, 102(3), 757-765. doi:10.1111/j.1365-2672.2006.03124.x

DOI: 10.1111/j.1365-2672.2006.03124.x

2006

The effect of silica nanoparticulate coatings on serum protein adsorption and cellular response (Journal article)

Lord, M. S., Cousins, B. G., Doherty, P. J., Whitelock, J. M., Simmons, A., Williams, R. L., & Milthorpe, B. K. (2006). The effect of silica nanoparticulate coatings on serum protein adsorption and cellular response. BIOMATERIALS, 27(28), 4856-4862. doi:10.1016/j.biomaterials.2006.05.037

DOI: 10.1016/j.biomaterials.2006.05.037

Modification of the surface properties of a lens material to influence posterior capsular opacification (Journal article)

Yuen, C., Williams, R., Batterbury, M., & Grierson, I. (2006). Modification of the surface properties of a lens material to influence posterior capsular opacification. CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 34(6), 568-574. doi:10.1111/j.1442-9071.2006.01278.x

DOI: 10.1111/j.1442-9071.2006.01278.x

Reflection anisotropy spectroscopy study of the adsorption of sulfur-containing amino acids at the Au(110)/electrolyte interface (Journal article)

LeParc, R., Smith, C. I., Cuquerella, M. C., Williams, R. L., Fernig, D. G., Edwards, C., . . . Weightman, P. (2006). Reflection anisotropy spectroscopy study of the adsorption of sulfur-containing amino acids at the Au(110)/electrolyte interface. LANGMUIR, 22(7), 3413-3420. doi:10.1021/la052584u

DOI: 10.1021/la052584u

2005

Polyurethanes as potential substrates for sub-retinal retinal pigment epithelial cell transplantation (Journal article)

Williams, R. L., Krishna, Y., Dixon, S., Haridas, A., Grierson, I., & Sheridan, C. (2005). Polyurethanes as potential substrates for sub-retinal retinal pigment epithelial cell transplantation. JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 16(12), 1087-1092. doi:10.1007/s10856-005-4710-y

DOI: 10.1007/s10856-005-4710-y

Sialin, an anion transporter defective in sialic acid storage diseases, shows highly variable expression in adult mouse brain, and is developmentally regulated. (Journal article)

Yarovaya, N., Schot, R., Fodero, L., McMahon, M., Mahoney, A., Williams, R., . . . Venter, D. J. (2005). Sialin, an anion transporter defective in sialic acid storage diseases, shows highly variable expression in adult mouse brain, and is developmentally regulated.. Neurobiology of disease, 19(3), 351-365. doi:10.1016/j.nbd.2004.12.020

DOI: 10.1016/j.nbd.2004.12.020

What pressure is exerted on the retina by heavy tamponade agents? (Journal article)

Wong, D., Williams, R., Stappler, T., & Groenewald, C. (2005). What pressure is exerted on the retina by heavy tamponade agents?. GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 243(5), 474-477. doi:10.1007/s00417-004-1047-z

DOI: 10.1007/s00417-004-1047-z

The Tamponade Effect (Chapter)

Wong, D., & Williams, R. (n.d.). The Tamponade Effect. In Essentials in Ophthalmology (pp. 147-161). Springer-Verlag. doi:10.1007/3-540-27152-x_10

DOI: 10.1007/3-540-27152-x_10

2004

Stability of plasma-treated silicone rubber and its influence on the interfacial aspects of blood compatibility (Journal article)

Williams, R. L., Wilson, D. J., & Rhodes, N. P. (2004). Stability of plasma-treated silicone rubber and its influence on the interfacial aspects of blood compatibility. BIOMATERIALS, 25(19), 4659-4673. doi:10.1016/j.biomaterials.2003.12.010

DOI: 10.1016/j.biomaterials.2003.12.010

Tamponade efficiency of perfluorohexyloctane and silicone oil solutions in a model eye chamber (Journal article)

Wetterqvist, C., Wong, D., Williams, R., Stappler, T., Herbert, E., & Freeburn, S. (2004). Tamponade efficiency of perfluorohexyloctane and silicone oil solutions in a model eye chamber. BRITISH JOURNAL OF OPHTHALMOLOGY, 88(5), 692-696. doi:10.1136/bjo.2003.024737

DOI: 10.1136/bjo.2003.024737

The effect of silica nanoparticulate coatings on cellular response (Journal article)

Cousins, B. G., Doherty, P. J., Williams, R. L., Fink, J., & Garvey, M. J. (2004). The effect of silica nanoparticulate coatings on cellular response. JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 15(4), 355-359. doi:10.1023/B:JMSM.0000021101.64938.b3

DOI: 10.1023/B:JMSM.0000021101.64938.b3

Tamponade properties of double-filling with perfluorohexyloctane and silicone oil in a model eye chamber (Journal article)

Herbert, E., Stappler, T., Wetterqvist, C., Williams, R., & Wong, D. (2004). Tamponade properties of double-filling with perfluorohexyloctane and silicone oil in a model eye chamber. GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 242(3), 250-254. doi:10.1007/s00417-003-0830-6

DOI: 10.1007/s00417-003-0830-6

A sinking filling: The use of a model eye chamber to study the behaviour of tamponade agents (Journal article)

Wong, D., Stappler, T., & Williams, R. (2004). A sinking filling: The use of a model eye chamber to study the behaviour of tamponade agents. Ophthalmo-Chirurgie., 16, 147-150.

Basement membranes and artificial substrates in cell transplantation (Journal article)

Sheridan, C., Williams, R., & Grierson, I. (2004). Basement membranes and artificial substrates in cell transplantation. GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 242(1), 68-75. doi:10.1007/s00417-003-0800-z

DOI: 10.1007/s00417-003-0800-z

Corrosion (Chapter)

Williams, R. L. (2004). Corrosion. In L. B. Gary, & E. W. Gary (Eds.), the Encyclopedia of Biomaterials and Biomedical Engineering (pp. 399-406). New York: Marcel Dekker, Inc,..

Degradative effects of the biological environment on metals and ceramics (Chapter)

Williams, D. F., & Williams, R. L. (2004). Degradative effects of the biological environment on metals and ceramics. In B. Ratner, A. Hoffman, J. Lemons, & F. Schoen (Eds.), Biomaterials Science: An Introduction to Materials in Medicine (pp. 430-439). San Diego: Academic Press.

Nickel and Nickel Alloys (Chapter)

Williams, R. L. (2004). Nickel and Nickel Alloys. In G. L. Bowlin, & G. E. Wnek (Eds.), Encyclopedia of Biomaterials and Biomedical Engineering (pp. 1066-1074). New York: Marcel Dekker, Inc,.

The effect of silica nanoparticulate coatings on cellular response (Journal article)

Cousins, B. G., Doherty, P. J., Fink, J., Garvey, M. J., & Williams, R. L. (2004). The effect of silica nanoparticulate coatings on cellular response. J. Mater. Sci: Mater. in Med., 15, 353-357.

2003

Biomaterial substrates (PTFE case) (Patent)

Williams, R. L., Garvey, M. J., Fink, J., Williams, R. L., Fink, J., Doherty, P. J., . . . Garvey, M. J. (2003). Biomaterial substrates (PTFE case).

How can combinations of F6H8 and silicone oil be used in the treatment of retinal detachments? (Journal article)

Wetterqvist, C., Wong, D., Williams, R., Stappler, T., Herbert, E., & Freeburn, S. (2003). How can combinations of F6H8 and silicone oil be used in the treatment of retinal detachments?. Ophthalmic Res., 35(S1), 237.

Polymer membranes for RPE transplantation (Journal article)

Williams, R. L., Sheridan, C., & Grierson, I. (2003). Polymer membranes for RPE transplantation. Ophthalmic Res., 35(S1), 3344.

Surface modification of a segmented polyetherurethane using a low-powered gas plasma and its influence on the activation of the coagulation system (Journal article)

Wilson, D. J., Rhodes, N. P., & Williams, R. L. (2003). Surface modification of a segmented polyetherurethane using a low-powered gas plasma and its influence on the activation of the coagulation system. BIOMATERIALS, 24(28), 5069-5081. doi:10.1016/S0142-9612(03)00423-X

DOI: 10.1016/S0142-9612(03)00423-X

2002

Substrates (Silica case) (Patent)

Williams, R. L., Garvey, M. J., Fink, J., Williams, R. L., Fink, J., Doherty, P. J., . . . Garvey, M. J. (2002). Substrates (Silica case).

The effect of thermocycling on five adhesive luting cements (Journal article)

Barclay, C. W., Boyle, E. L., Williams, R., & Marquis, P. M. (2002). The effect of thermocycling on five adhesive luting cements. JOURNAL OF ORAL REHABILITATION, 29(6), 546-552. doi:10.1046/j.1365-2842.2002.00882.x

DOI: 10.1046/j.1365-2842.2002.00882.x

Effects of plasma treated PET and PTFE on expression of adhesion molecules by human endothelial cells in vitro (Journal article)

Pu, F. R., Williams, R. L., Markkula, T. K., & Hunt, J. A. (2002). Effects of plasma treated PET and PTFE on expression of adhesion molecules by human endothelial cells in vitro. BIOMATERIALS, 23(11), 2411-2428. doi:10.1016/S0142-9612(01)00377-5

DOI: 10.1016/S0142-9612(01)00377-5

Expression of leukocyte-endothelial cell adhesion molecules on monocyte adhesion to human endothelial cells on plasma treated PET and PTFE in vitro (Journal article)

Pu, F. R., Williams, R. L., Markkula, T. K., & Hunt, J. A. (2002). Expression of leukocyte-endothelial cell adhesion molecules on monocyte adhesion to human endothelial cells on plasma treated PET and PTFE in vitro. BIOMATERIALS, 23(24), 4705-4718. doi:10.1016/S0142-9612(02)00219-3

DOI: 10.1016/S0142-9612(02)00219-3

Surface chemical derivatization of plasma-treated PET and PTFE (Journal article)

Markkula, T. K., Hunt, J. A., Pu, F. R., & Williams, R. L. (2002). Surface chemical derivatization of plasma-treated PET and PTFE. SURFACE AND INTERFACE ANALYSIS, 34(1), 583-587. doi:10.1002/sia.1365

DOI: 10.1002/sia.1365

2001

An X-ray Photoelectron Spectroscopy study of biomedical polyurethane modified using low-power plasma (Journal article)

Kitching, K. J., Wilson, D. J., Doherty, P. J., & Williams, R. L. (2001). An X-ray Photoelectron Spectroscopy study of biomedical polyurethane modified using low-power plasma. Journal of X-Ray Science and Technology, 9(2), 77-83.

Endoscopic-guided trephination dacryocystorhinostomy (Hesham DCR) - Technique and pilot trial (Journal article)

Ibrahim, H. A., Noble, J. L., Batterbury, M., Johnson, C. P., & Williams, R. (2001). Endoscopic-guided trephination dacryocystorhinostomy (Hesham DCR) - Technique and pilot trial. OPHTHALMOLOGY, 108(12), 2337-2345. doi:10.1016/S0161-6420(01)00813-2

DOI: 10.1016/S0161-6420(01)00813-2

The influence of bracket type on the force delivery of Ni-Ti archwires (Journal article)

Hemingway, R., Williams, R. L., Hunt, J. A., & Rudge, S. J. (2001). The influence of bracket type on the force delivery of Ni-Ti archwires. EUROPEAN JOURNAL OF ORTHODONTICS, 23(3), 233-241. doi:10.1093/ejo/23.3.233

DOI: 10.1093/ejo/23.3.233

Plasma modification of PTFE surfaces Part II: Plasma-treated surfaces following storage in air or PBS (Journal article)

Wilson, D. J., Williams, R. L., & Pond, R. C. (2001). Plasma modification of PTFE surfaces Part II: Plasma-treated surfaces following storage in air or PBS. SURFACE AND INTERFACE ANALYSIS, 31(5), 397-408. doi:10.1002/sia.1066

DOI: 10.1002/sia.1066

Monocyte adhesion and adhesion molecule expression on human endothelial cells on plasma treated PET and PTFE in vitro (Journal article)

Pu, F. R., Williams, R. L., Markkula, T., & Hunt, J. A. (2001). Monocyte adhesion and adhesion molecule expression on human endothelial cells on plasma treated PET and PTFE in vitro. J. Mater. Sci: Mater. in Med. Special Issue,, 12, 970-977.

Monocyte adhesion and adhesion molecule expression on human endothelial cells on plasma-treated PET and PTFE in vitro (Journal article)

Pu, F. R., Williams, R. L., Markkula, T. K., & Hunt, J. A. (2001). Monocyte adhesion and adhesion molecule expression on human endothelial cells on plasma-treated PET and PTFE in vitro. JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 12(10-12), 971-977. doi:10.1023/A:1012861116388

DOI: 10.1023/A:1012861116388

Plasma modification of PTFE surfaces Part I: Surfaces immediately following plasma treatment (Journal article)

Wilson, D. J., Williams, R. L., & Pond, R. C. (2001). Plasma modification of PTFE surfaces Part I: Surfaces immediately following plasma treatment. SURFACE AND INTERFACE ANALYSIS, 31(5), 385-396. doi:10.1002/sia.1065

DOI: 10.1002/sia.1065

2000

Wettability of chemically modified polymers: Experiment and theory (Journal article)

Wilson, D. J., Pond, R. C., & Williams, R. L. (2000). Wettability of chemically modified polymers: Experiment and theory. INTERFACE SCIENCE, 8(4), 389-399. doi:10.1023/A:1008735929894

DOI: 10.1023/A:1008735929894

Surface chemistry and wettability of plasma-treated PTFE (Journal article)

Wilson, D. J., Eccles, A. J., Steele, T. A., Williams, R. L., & Pond, R. C. (2000). Surface chemistry and wettability of plasma-treated PTFE. SURFACE AND INTERFACE ANALYSIS, 30(1), 36-39. doi:3.0.CO;2-Z">10.1002/1096-9918(200008)30:1<36::AID-SIA801>3.0.CO;2-Z

DOI: 10.1002/1096-9918(200008)30:1<36::AID-SIA801>3.0.CO;2-Z

Biomaterials used in the posterior segment of the eye (Journal article)

Colthurst, M. J., Williams, R. L., Hiscott, P. S., & Grierson, I. (2000). Biomaterials used in the posterior segment of the eye. BIOMATERIALS, 21(7), 649-665. doi:10.1016/S0142-9612(99)00220-3

DOI: 10.1016/S0142-9612(99)00220-3

Gas plasma modification of PET and PTFE (Journal article)

Markkula, T., Hunt, J. A., Pu, F., & Williams, R. L. (2000). Gas plasma modification of PET and PTFE. UKSB First Annual Conference 6-7th July 2000, 35.

1999

The influence of explants on the physical efficiency of tamponade agents (Journal article)

Williams, R., & Wong, D. (1999). The influence of explants on the physical efficiency of tamponade agents. GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 237(10), 870-874. doi:10.1007/s004170050325

DOI: 10.1007/s004170050325

Conjoint corrosion and wear in titanium alloys (Journal article)

Khan, M. A., Williams, R. L., & Williams, D. F. (1999). Conjoint corrosion and wear in titanium alloys. BIOMATERIALS, 20(8), 765-772. doi:10.1016/S0142-9612(98)00229-4

DOI: 10.1016/S0142-9612(98)00229-4

The corrosion behaviour of Ti-6Al-4V, Ti-6Al-7Nb and Ti-13Nb-13Zr in protein solutions (Journal article)

Khan, M. A., Williams, R. L., & Williams, D. F. (1999). The corrosion behaviour of Ti-6Al-4V, Ti-6Al-7Nb and Ti-13Nb-13Zr in protein solutions. BIOMATERIALS, 20(7), 631-637. doi:10.1016/S0142-9612(98)00217-8

DOI: 10.1016/S0142-9612(98)00217-8

1998

Exchange of perfluorodecalin for gas or oil: a model for avoiding slippage (Journal article)

Wong, D., Williams, R. L., & German, M. J. (1998). Exchange of perfluorodecalin for gas or oil: a model for avoiding slippage. GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 236(3), 234-237. doi:10.1007/s004170050070

DOI: 10.1007/s004170050070

1997

A study of cell behaviour on the surfaces of multifilament materials (Journal article)

Wan, H., Williams, R. L., Doherty, P. J., & Williams, D. F. (1997). A study of cell behaviour on the surfaces of multifilament materials. JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 8(1), 45-51. doi:10.1023/A:1018542313236

DOI: 10.1023/A:1018542313236

1996

The clinical assessment of a ceramic-coated transmucosal dental implant collar (Journal article)

Barclay, C. W., Last, K. S., & Williams, R. (1996). The clinical assessment of a ceramic-coated transmucosal dental implant collar. INTERNATIONAL JOURNAL OF PROSTHODONTICS, 9(5), 466-472. Retrieved from https://www.webofscience.com/

Titanium alloys - corrosion and wear studies in-vitro (Conference Paper)

Khan, M. A., Williams, R. L., & Williams, D. F. (1996). Titanium alloys - corrosion and wear studies in-vitro. In Transactions of the Annual Meeting of the Society for Biomaterials in conjunction with the International Biomaterials Symposium Vol. 2 (pp. 480).

In-vitro corrosion and wear of titanium alloys in the biological environment (Journal article)

Khan, M. A., Williams, R. L., & Williams, D. F. (1996). In-vitro corrosion and wear of titanium alloys in the biological environment. BIOMATERIALS, 17(22), 2117-2126. doi:10.1016/0142-9612(96)00029-4

DOI: 10.1016/0142-9612(96)00029-4

1995

Laser surface modification of polymers to improve biocompatibility (Journal article)

Hunt, J. A., Williams, R. L., Tavakoli, S. M., & Riches, S. T. (1995). Laser surface modification of polymers to improve biocompatibility. JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 6(12), 813-817. doi:10.1007/BF00134323

DOI: 10.1007/BF00134323

Adherence of silicone oil to intraocular lenses. (Journal article)

Wong, D., Williams, R., & Batterbury, M. (1995). Adherence of silicone oil to intraocular lenses.. Eye (London, England), 9 ( Pt 4), 539. doi:10.1038/eye.1995.126

DOI: 10.1038/eye.1995.126

FIBROBLAST ADHESION ONTO METHYL-SILICA GRADIENTS WITH AND WITHOUT PREADSORBED PROTEIN (Journal article)

WILLIAMS, R. L., HUNT, J. A., & TENGVALL, P. (1995). FIBROBLAST ADHESION ONTO METHYL-SILICA GRADIENTS WITH AND WITHOUT PREADSORBED PROTEIN. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH, 29(12), 1545-1555. doi:10.1002/jbm.820291211

DOI: 10.1002/jbm.820291211

1994

The tensile and shear bond strength of a conventional and a 4-meta self-cure acrylic resin to various surface finishes of CoCr alloy. (Journal article)

Barclay, C. W., & Williams, R. (1994). The tensile and shear bond strength of a conventional and a 4-meta self-cure acrylic resin to various surface finishes of CoCr alloy.. The European journal of prosthodontics and restorative dentistry, 3(1), 5-9.

CONTACT ANGLES OF SUBSTANCES USED FOR INTERNAL TAMPONADE IN RETINAL-DETACHMENT SURGERY (Journal article)

FAWCETT, I. M., WILLIAMS, R. L., & WONG, D. (1994). CONTACT ANGLES OF SUBSTANCES USED FOR INTERNAL TAMPONADE IN RETINAL-DETACHMENT SURGERY. GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 232(7), 438-444. doi:10.1007/BF00186587

DOI: 10.1007/BF00186587

A PRELIMINARY ASSESSMENT OF POLY(PYRROLE) IN NERVE GUIDE STUDIES (Journal article)

WILLIAMS, R. L., & DOHERTY, P. J. (1994). A PRELIMINARY ASSESSMENT OF POLY(PYRROLE) IN NERVE GUIDE STUDIES. JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 5(6-7), 429-433. doi:10.1007/BF00058978

DOI: 10.1007/BF00058978

THE CYTOTOXICITY EVALUATION OF KEVLAR AND SILICON-CARBIDE BY MTT ASSAY (Journal article)

WAN, H., WILLIAMS, R. L., DOHERTY, P. J., & WILLIAMS, D. F. (1994). THE CYTOTOXICITY EVALUATION OF KEVLAR AND SILICON-CARBIDE BY MTT ASSAY. JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 5(6-7), 441-445. doi:10.1007/BF00058980

DOI: 10.1007/BF00058980

A STUDY OF THE REPRODUCIBILITY OF THE MTT TEST (Journal article)

WAN, H., WILLIAMS, R., DOHERTY, P., & WILLIAMS, D. F. (1994). A STUDY OF THE REPRODUCIBILITY OF THE MTT TEST. JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 5(3), 154-159. doi:10.1007/BF00053336

DOI: 10.1007/BF00053336

BIODEGRADATION OF HYALURONIC-ACID DERIVATIVES BY HYALURONIDASE (Journal article)

ZHONG, S. P., CAMPOCCIA, D., DOHERTY, P. J., WILLIAMS, R. L., BENEDETTI, L., & WILLIAMS, D. F. (1994). BIODEGRADATION OF HYALURONIC-ACID DERIVATIVES BY HYALURONIDASE. BIOMATERIALS, 15(5), 359-365. doi:10.1016/0142-9612(94)90248-8

DOI: 10.1016/0142-9612(94)90248-8

BIOMECHANICAL ANALYSIS OF A NEW EXTERNAL FIXATION SYSTEM AND ITS CLINICAL-SIGNIFICANCE (Journal article)

WILLIAMS, R. L., AGGARWAL, N. K., & KLENERMAN, L. (1994). BIOMECHANICAL ANALYSIS OF A NEW EXTERNAL FIXATION SYSTEM AND ITS CLINICAL-SIGNIFICANCE. JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE, 37(1), 66-73. doi:10.1097/00005373-199407000-00013

DOI: 10.1097/00005373-199407000-00013

THE ADHERENCE OF SILICONE OIL TO STANDARD AND HEPARIN-COATED PMMA INTRAOCULAR LENSES (Journal article)

BATTERBURY, M., WONG, D., WILLIAMS, R., & BATES, R. (1994). THE ADHERENCE OF SILICONE OIL TO STANDARD AND HEPARIN-COATED PMMA INTRAOCULAR LENSES. EYE, 8, 547-549. doi:10.1038/eye.1994.135

DOI: 10.1038/eye.1994.135

1993

Non-invasive magnetic resonance imaging of the soft tissue response to a biomaterial. (Journal article)

Khor, E., Hunt, J. A., Martin, P. A., Doherty, P. J., Williams, R. L., & Williams, D. F. (1993). Non-invasive magnetic resonance imaging of the soft tissue response to a biomaterial.. Clinical materials, 12(2), 65-72. doi:10.1016/0267-6605(93)90051-8

DOI: 10.1016/0267-6605(93)90051-8

1992

Biomaterial-Tissue Interfaces (Book)

Doherty, P. J., Williams, R. L., Williams, D. F., & Lee, A. J. C. (Eds.) (1992). Biomaterial-Tissue Interfaces (Vol. 10). Amsterdam: Elsevier.

PERIBULBAR ANESTHESIA - FAILURE TO ABOLISH THE OCULOCARDIAC REFLEX (Journal article)

BATTERBURY, M., WONG, D., WILLIAMS, R., KELLY, J., & MOSTAFA, S. M. (1992). PERIBULBAR ANESTHESIA - FAILURE TO ABOLISH THE OCULOCARDIAC REFLEX. EYE, 6, 293-295. doi:10.1038/eye.1992.57

DOI: 10.1038/eye.1992.57

1991

XPS STUDIES OF THE BONDING AND HYDROLYSIS OF DENTIN BONDING AGENTS (Journal article)

WILLIAMS, R. L., ALI, S. A. M., & WILLIAMS, D. F. (1991). XPS STUDIES OF THE BONDING AND HYDROLYSIS OF DENTIN BONDING AGENTS. SURFACE AND INTERFACE ANALYSIS, 17(7), 496-498. doi:10.1002/sia.740170714

DOI: 10.1002/sia.740170714

1989

THE SPATIAL-RESOLUTION OF PROTEIN ADSORPTION ON SURFACES OF HETEROGENEOUS METALLIC BIOMATERIALS (Journal article)

WILLIAMS, R. L., & WILLIAMS, D. F. (1989). THE SPATIAL-RESOLUTION OF PROTEIN ADSORPTION ON SURFACES OF HETEROGENEOUS METALLIC BIOMATERIALS. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH, 23(3), 339-350. doi:10.1002/jbm.820230305

DOI: 10.1002/jbm.820230305

1988

ALBUMIN ADSORPTION ON METAL-SURFACES (Journal article)

WILLIAMS, R. L., & WILLIAMS, D. F. (1988). ALBUMIN ADSORPTION ON METAL-SURFACES. BIOMATERIALS, 9(3), 206-212. doi:10.1016/0142-9612(88)90085-3

DOI: 10.1016/0142-9612(88)90085-3

ELECTROCHEMICAL STUDIES ON THE INFLUENCE OF PROTEINS ON THE CORROSION OF IMPLANT ALLOYS (Journal article)

WILLIAMS, R. L., BROWN, S. A., & MERRITT, K. (1988). ELECTROCHEMICAL STUDIES ON THE INFLUENCE OF PROTEINS ON THE CORROSION OF IMPLANT ALLOYS. BIOMATERIALS, 9(2), 181-186. doi:10.1016/0142-9612(88)90119-6

DOI: 10.1016/0142-9612(88)90119-6

THE EFFECT OF ALBUMIN ON THE WETTABILITY OF PURE METAL AND METAL-OXIDE SURFACES (Journal article)

WILLIAMS, R. L., & WILLIAMS, D. F. (1988). THE EFFECT OF ALBUMIN ON THE WETTABILITY OF PURE METAL AND METAL-OXIDE SURFACES. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 126(2), 596-603. doi:10.1016/0021-9797(88)90159-2

DOI: 10.1016/0021-9797(88)90159-2

1987

Expansion of a Successful In-Situ Combustion Pilot in the Midway Sunset Field (Conference Paper)

Williams, R. L., Jones, J. A., & Counihan, T. M. (1987, September 27). Expansion of a Successful In-Situ Combustion Pilot in the Midway Sunset Field. In Proceedings of SPE Annual Technical Conference and Exhibition. Society of Petroleum Engineers. doi:10.2523/16873-ms

DOI: 10.2523/16873-ms

PUMP-OFF CONTROL APPLICATION IN THERMAL RECOVERY OPERATIONS. (Conference Paper)

Yoch, R. J., Williams, R. L., & Jones, J. A. (1987). PUMP-OFF CONTROL APPLICATION IN THERMAL RECOVERY OPERATIONS.. In Society of Petroleum Engineers of AIME, (Paper) SPE.

1984

TAFEL SLOPES IN SERUM AND SALINE WHITE STATIC AND FRETTING. (Conference Paper)

Williams, R. L., & Brown, S. A. (1984). TAFEL SLOPES IN SERUM AND SALINE WHITE STATIC AND FRETTING.. In Transactions of the Annual Meeting of the Society for Biomaterials in conjunction with the International Biomaterials Symposium Vol. 7 (pp. 181).

Publications

Selected Publications

2023

FluoroPi Device With SmartProbes: A Frugal Point-of-Care System for Fluorescent Detection of Bacteria From a Pre-Clinical Model of Microbial Keratitis. (Journal article)

Antimicrobial effect of nitric oxide releasing hydrogels on Staphylococcus aureus derived proteases (Journal article)

Antimicrobial Effect of Nitric Oxide Releasing Hydrogels on <i>Staphylococcus Aureus</i> Derived Proteases (Adv. Mater. Interfaces 15/2023) (Journal article)

The conjunctival extracellular matrix, related disorders and development of substrates for conjunctival restoration (Journal article)

2022

Scaffold-Free Strategy Using a PEG-Dextran Aqueous Two-Phase-System for Corneal Tissue Repair. (Journal article)

Antimicrobial Nitric Oxide-Releasing Electrospun Dressings for Wound Healing Applications (Journal article)

Amoebicidal Activity of Poly-Epsilon-Lysine Functionalized Hydrogels (Journal article)

Using CRISPR-Cas9 generated models to determine the role of laminin a5 polymerisation (Conference Paper)

2021

Melt electro-written scaffolds with box-architecture support orthogonally oriented collagen (Journal article)

3D reactive inkjet printing of poly-ɛ-lysine/gellan gum hydrogels for potential corneal constructs (Journal article)

Biological tissues and components, and synthetic substrates for conjunctival cell transplantation (Journal article)

Characterization of Tunable Poly-ε-Lysine-Based Hydrogels for Corneal Tissue Engineering. (Journal article)

Chemical Cross-Linking of Corneal Tissue to Reduce Progression of Loss of Sight in Patients With Keratoconus (Journal article)

Material Characterisation and Stratification of Conjunctival Epithelial Cells on Electrospun Poly(ε-Caprolactone) Fibres Loaded with Decellularised Tissue Matrices. (Journal article)

Learning Unsupervised Parameter-Specific Affine Transformation for Medical Images Registration (Conference Paper)

Plasma polymer surface modified expanded polytetrafluoroethylene promotes epithelial monolayer formation in vitro and can be transplanted into the dystrophic rat subretinal space (Journal article)

2020

A human retinal microvascular endothelial-pericyte co-culture model to study diabetic retinopathy in vitro (Journal article)

Exploratory use of fluorescent SmartProbes for the rapid detection of microbial isolates causing corneal ulcer. (Journal article)

Poly-ε-Lysine or Mel4 Antimicrobial Surface Modification on a Novel Peptide Hydrogel Bandage Contact Lens (Journal article)

Antimicrobial Activity of Poly-epsilon-lysine Peptide Hydrogels Against <i>Pseudomonas aeruginosa</i> (Journal article)

<i>In vitro</i> and computational modelling of drug delivery across the outer blood-retinal barrier (Journal article)

Mass Spectrometry Reveals α-2-HS-Glycoprotein as a Key Early Extracellular Matrix Protein for Conjunctival Cells (Journal article)

CRISPR-Cas9-mediated labelling of the C-terminus of human laminin β1 leads to secretion inhibition (Journal article)

Ophthalmic Biomaterials (Chapter)

2019

Proof on Concept: Semi-Automated Alignment of Evar Surveillance Radiographs – Increasing the Sensitivity to Device Migration and Distortion (Journal article)

Antimicrobial nitric oxide releasing contact lens gels for the treatment of microbial keratitis. (Journal article)

Poly-ε-lysine based hydrogels as synthetic substrates for the expansion of corneal endothelial cells for transplantation (Journal article)

Plasma Polymer Coatings To Direct the Differentiation of Mouse Kidney-Derived Stem Cells into Podocyte and Proximal Tubule-like Cells (Journal article)

Learning Active Contour Models for Medical Image Segmentation (Conference Paper)

Plasma Polymerisation Using Helium Atmospheric-Pressure Plasma Jet with Heptylamine Monomer (Journal article)

Cover Picture: Plasma Process. Polym. 4/2019 (Journal article)

Biomaterials in Ophthalmology (Chapter)

INCORPORATION OF ENDOTHELIAL COLONY FORMING CELLS INTO AN IN VITRO HUMAN PRIMARY CO-CULTURE MODEL OF DIABETIC RETINOPATHY (Conference Paper)

Laminin β1 with C-terminal Dendra2 fluorescent protein tag is inefficiently secreted from lung adenocarcinoma cells in culture (Conference Paper)

Learning Active Contour Models for Medical Image Segmentation. (Conference Paper)

2018

Biomaterials for Regenerative Medicine Approaches for the Anterior Segment of the Eye (Journal article)

Developing Regenerative Medicine Strategies for Diabetic Retinopathy using Human Retinal Endothelial Cells (Conference Paper)

Modulated release from implantable ocular silicone oil tamponade drug reservoirs (Journal article)

Development of decellularized conjunctiva as a substrate for the <i>ex vivo</i> expansion of conjunctival epithelium (Journal article)

2017

The Role of Controlled Surface Topography and Chemistry on Mouse Embryonic Stem Cell Attachment, Growth and Self-Renewal (Journal article)

Development of a Poly-epsilon-lysine Contact Lens for Drug Delivery in the Management of Fungal Keratitis (Conference Paper)

Development of a Poly-ε-lysine Contact Lens as a Drug Delivery Device for the Treatment of Fungal Keratitis (Journal article)

The formation of a functional retinal pigment epithelium occurs on porous polytetrafluoroethylene substrates independently of the surface chemistry (Journal article)

Towards better characterization and quantification of emulsification of silicone oil in vitro (Journal article)

2016

Controlling drug release from non-aqueous environments: Moderating delivery from ocular silicone oil drug reservoirs to combat proliferative vitreoretinopathy (Journal article)

A Novel Peptide Hydrogel for an Antimicrobial Bandage Contact Lens (Journal article)

2015

Development of emulsification resistant heavier-than-water tamponades using high molecular weight silicone oil polymers (Journal article)

Biomaterials for ocular reconstruction (Journal article)

Distal fixation forces of different endovascular limb extensions in an experimental porcine model (Journal article)

Haemodynamic Evidence that Large Iliac Arteries Increase the Risk of Limb Migration following Endovascular Aneurysm Repair (Conference Paper)

2014

Flow Behavior of Heavy Silicone Oil During Eye Movements (Journal article)

Fibrinogen adsorption and platelet adhesion to silica surfaces with stochastic nanotopography (Journal article)

Computational Fluid Dynamic (CFD) analysis of the distraction forces experienced by stent-grafts following fEVAR (Conference Paper)

Computational fluid dynamic analysis of the effect of morphologic features on distraction forces in fenestrated stent grafts (Journal article)

2013

Novel Heavy Tamponade for Vitreoretinal Surgery (Journal article)

Polystyrene Surface Modification for Localized Cell Culture Using a Capillary Dielectric Barrier Discharge Atmospheric-Pressure Microplasma Jet (Journal article)

Characterization of the interface between adsorbed fibronectin and human embryonic stem cells (Journal article)

Complications related to the tamponade agent: Emulsification of tamponade agents (Chapter)

The influence of high intensity terahertz radiation on mammalian cell adhesion, proliferation and differentiation (Journal article)

Degradative Effects of the Biological Environment on Metals and Ceramics (Chapter)

Guided gingival fibroblast attachment to titanium surfaces: an in vitro study (Journal article)

Induction of mesenchymal stem cell chondrogenesis by polyacrylate substrates (Journal article)

2012

Plasma polymer coatings to aid retinal pigment epithelial growth for transplantation in the treatment of age related macular degeneration (Journal article)

Characteristics Of Rat Iris Pigment Epithelial Cells Cultured On Modified Expanded-polytetrafluroethylene (ePTFE) Substrates (Conference Paper)

GROWTH OF PORCINE IRIS PIGMENTED EPITHELIAL CELLS ON SUBSTRATES FOR THE TREATMENT OF AGE RELATED MACULAR DEGENERATION (AMD) (Conference Paper)

QUANTIFICATION OF RETINAL THICKNESS FOLLOWING IMPLANTATION OF ACELLULAR SURFACE-MODIFIED EXPANDED POLYTETRAFLUOROETHYLENE (EPTFE) IN A RABBIT MODEL USING SD-OCT AND HISTOLOGY (Conference Paper)

The status of the alice r&d facility at stfc daresbury laboratory (Conference Paper)