Photo of Dr Jude Curran

Dr Jude Curran BEng (Hons) PhD

Lecturer Mechanical, Materials & Aerospace Eng

Publications

Selected Publications

  1. The osteogenic response of mesenchymal stem cells to an injectable PLGA bone regeneration system (Journal article - 2013)
  2. The use of dynamic surface chemistries to control MSC isolation and function (Journal article - 2011)
  3. Introducing dip pen nanolithography as a tool for controlling stem cell behaviour: unlocking the potential of the next generation of smart materials in regenerative medicine (Journal article - 2010)
  4. Nanoscale definition of substrate materials to direct human adult stem cells towards tissue specific populations (Journal article - 2010)
  5. The guidance of human mesenchymal stem cell differentiation in vitro by controlled modifications to the cell substrate (Journal article - 2006)

2019

Control of Biological Responses by Isolated Synthetic Material Variables (Thesis / Dissertation)

Lee, I. (2019, May 10). Control of Biological Responses by Isolated Synthetic Material Variables.

Erratum to 'Involvement of Adenosine 5'-Triphosphate in Ultrasound-Induced Fracture Repair' [Ultrasound Med Biol 31 (2005) 1131-1138]. (Journal article)

Hayton, M. J., Parmar, K. L., Dillon, J. P., Glynn, D., Curran, J. M., Gallagher, J. A., & Buckley, K. A. (2019). Erratum to 'Involvement of Adenosine 5'-Triphosphate in Ultrasound-Induced Fracture Repair' [Ultrasound Med Biol 31 (2005) 1131-1138].. Ultrasound in medicine & biology. doi:10.1016/j.ultrasmedbio.2019.05.006

DOI: 10.1016/j.ultrasmedbio.2019.05.006

2018

Fluorescence-Based Nano-Oxygen Particles for Spatiometric Monitoring of Cell Physiological Conditions (Journal article)

Koduri, M. P., Goudar, V. S., Shao, Y. -W., Hunt, J. A., Henstock, J. R., Curran, J., & Tseng, F. G. (2018). Fluorescence-Based Nano-Oxygen Particles for Spatiometric Monitoring of Cell Physiological Conditions. ACS APPLIED MATERIALS & INTERFACES, 10(36), 30163-30171. doi:10.1021/acsami.8b10715

DOI: 10.1021/acsami.8b10715

Large-area Scanning Probe Nanolithography Facilitated by Automated Alignment and Its Application to Substrate Fabrication for Cell Culture Studies (Journal article)

Lee, I. -N., Hosford, J., Wang, S., Hunt, J. A., Curran, J. M., Heath, W. P., & Wong, L. S. (2018). Large-area Scanning Probe Nanolithography Facilitated by Automated Alignment and Its Application to Substrate Fabrication for Cell Culture Studies. JOVE-JOURNAL OF VISUALIZED EXPERIMENTS, (136). doi:10.3791/56967

DOI: 10.3791/56967

Photoresponsive Hydrogels with Photoswitchable Mechanical Properties Allow Time-Resolved Analysis of Cellular Responses to Matrix Stiffening (Journal article)

Lee, I. -N., Dobre, O., Richards, D., Ballestrem, C., Curran, J. M., Hunt, J. A., . . . Wong, L. S. (2018). Photoresponsive Hydrogels with Photoswitchable Mechanical Properties Allow Time-Resolved Analysis of Cellular Responses to Matrix Stiffening. ACS APPLIED MATERIALS & INTERFACES, 10(9), 7765-7776. doi:10.1021/acsami.7b18302

DOI: 10.1021/acsami.7b18302

The optimization and production of stable homogeneous amine enriched surfaces with characterized nanotopographical properties for enhanced osteoinduction of mesenchymal stem cells (Journal article)

Chen, R., Hunt, J. A., Fawcett, S., D'sa, R., Akhtar, R., & Curran, J. M. (2018). The optimization and production of stable homogeneous amine enriched surfaces with characterized nanotopographical properties for enhanced osteoinduction of mesenchymal stem cells. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 106(7), 1862-1877. doi:10.1002/jbm.a.36383

DOI: 10.1002/jbm.a.36383

2017

Correction: Introducing dip pen nanolithography as a tool for controlling stem cell behaviour: unlocking the potential of the next generation of smart materials in regenerative medicine. (Journal article)

Curran, J. M., Stokes, R., Irvine, E., Graham, D., Amro, N. A., Sanedrin, R. G., . . . Hunt, J. A. (2017). Introducing dip pen nanolithography as a tool for controlling stem cell behaviour: unlocking the potential of the next generation of smart materials in regenerative medicine (vol 10, pg 1662, 2010). LAB ON A CHIP, 17(12), 2135-2138. doi:10.1039/c7lc90059g

DOI: 10.1039/c7lc90059g

In Vitro Response of Human Peripheral Blood Mononuclear Cells (PBMC) to Collagen Films Treated with Cold Plasma (Journal article)

Chen, R., Curran, J., Pu, F., Zhuola, Z., Bayon, Y., & Hunt, J. A. (2017). In Vitro Response of Human Peripheral Blood Mononuclear Cells (PBMC) to Collagen Films Treated with Cold Plasma. POLYMERS, 9(7). doi:10.3390/polym9070254

DOI: 10.3390/polym9070254

2016

Defining the Properties of an Array of -NH2-Modified Substrates for the Induction of a Mature Osteoblast/Osteocyte Phenotype from a Primary Human Osteoblast Population Using Controlled Nanotopography and Surface Chemistry (Journal article)

Fawcett, S. A., Curran, J. M., Chen, R., Rhodes, N. P., Murphy, M. F., Wilson, P., . . . Hunt, J. A. (2017). Defining the Properties of an Array of -NH2-Modified Substrates for the Induction of a Mature Osteoblast/Osteocyte Phenotype from a Primary Human Osteoblast Population Using Controlled Nanotopography and Surface Chemistry. CALCIFIED TISSUE INTERNATIONAL, 100(1), 95-106. doi:10.1007/s00223-016-0202-y

DOI: 10.1007/s00223-016-0202-y

2015

Human mesenchymal stem cell response to poly(ε-caprolactone/poly(methyl methacrylate) demixed thin films (Journal article)

Khattak, M., Pu, F., Curran, J. M., Hunt, J. A., & D’Sa, R. A. (2015). Human mesenchymal stem cell response to poly(ε-caprolactone/poly(methyl methacrylate) demixed thin films. Journal of Materials Science: Materials in Medicine, 26(5). doi:10.1007/s10856-015-5507-2

DOI: 10.1007/s10856-015-5507-2

2013

The osteogenic response of mesenchymal stem cells to an injectable PLGA bone regeneration system (Journal article)

Curran, J. M., Fawcett, S., Hamilton, L., Rhodes, N. P., Rahman, C. V., Alexander, M., . . . Hunt, J. A. (2013). The osteogenic response of mesenchymal stem cells to an injectable PLGA bone regeneration system. BIOMATERIALS, 34(37), 9352-9364. doi:10.1016/j.biomaterials.2013.08.044

DOI: 10.1016/j.biomaterials.2013.08.044

2011

Patterned surfaces and methods of use for stem cell culture (Patent)

Hunt, J. A., & 5, J. M. C. +. (2011). Patterned surfaces and methods of use for stem cell culture.

The use of dynamic surface chemistries to control MSC isolation and function (Journal article)

Curran, J. M., Pu, F., Chen, R., & Hunt, J. A. (2011). The use of dynamic surface chemistries to control MSC isolation and function. Biomaterials, 32(21), 4753-4760.

The use of dynamic surface chemistries to control msc isolation and function (Journal article)

Curran, J. M., Pu, F., Chen, R., & Hunt, J. A. (2011). The use of dynamic surface chemistries to control msc isolation and function. BIOMATERIALS, 32(21), 4753-4760. doi:10.1016/j.biomaterials.2011.03.045

DOI: 10.1016/j.biomaterials.2011.03.045

2010

An Evaluation of Four Surface Modifications and their Ability to Promote Human Mesenchymal Stem Cell Differentiation on PLGA Spheres (Conference Paper)

Fawcett, S., Curran, J. M., Hamilton, L., Rhodes, N. P., Shakesheff, K. M., & Hunt, J. A. (2010). An Evaluation of Four Surface Modifications and their Ability to Promote Human Mesenchymal Stem Cell Differentiation on PLGA Spheres. In UKSB. Glasgow.

Harnessing Material Induced Cell interactions to Develop Cost Effective Regenerative Medicine Solutions: The Journey from Bench to Body (Conference Paper)

Curran, J. M. (2010). Harnessing Material Induced Cell interactions to Develop Cost Effective Regenerative Medicine Solutions: The Journey from Bench to Body. In TCES 2010. Manchester.

Increased Efficiency of Material Induced Cell Behavior using Optimized Nano-patterned Arrays; Increasing the Power of the Substrate on a Cellular Response (Conference Paper)

Curran, J. M., Chen, R., Hernandez-Santana, A., Graham, D., Amro, N., Sanderin, R., . . . Hunt, J. A. (2010). Increased Efficiency of Material Induced Cell Behavior using Optimized Nano-patterned Arrays; Increasing the Power of the Substrate on a Cellular Response. In TERMIS. Galway.

Introducing dip pen nanolithography as a tool for controlling stem cell behaviour: unlocking the potential of the next generation of smart materials in regenerative medicine (Journal article)

Curran, J. M., Stokes, R., Irvine, E., Graham, D., Amro, N. A., Sanedrin, R. G., . . . Hunt, J. A. (2010). Introducing dip pen nanolithography as a tool for controlling stem cell behaviour: unlocking the potential of the next generation of smart materials in regenerative medicine. LAB ON A CHIP, 10(13), 1662-1670. doi:10.1039/c004149a

DOI: 10.1039/c004149a

Material Induced Mesenchymal Stem Cell Differentiation (Journal article)

Curran, J. M., Chen, R., & Hunt, J. A. (2010). Material Induced Mesenchymal Stem Cell Differentiation. BIOMATERIALS, 31(6). Retrieved from http://gateway.webofknowledge.com/

Materials and Methods for Cell Growth (Patent)

Hunt, J. A., Curran, J. M., Graham, D., & Stokes, R. (2010). Materials and Methods for Cell Growth.

Nanoscale definition of substrate materials to direct human adult stem cells towards tissue specific populations (Journal article)

Curran, J. M., Chen, R., Stokes, R., Irvine, E., Graham, D., Gubbins, E., . . . Hunt, J. A. (2010). Nanoscale definition of substrate materials to direct human adult stem cells towards tissue specific populations. JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 21(3), 1021-1029. doi:10.1007/s10856-009-3976-x

DOI: 10.1007/s10856-009-3976-x

Surface Modification of an Injectable Scaffold to Induce osteogenic Differentiation of Human MSC; (Conference Paper)

Hamilton, L., Fawcett, S., Curran, J. M., Rhodes, N. P., Hunt, J. A., Alexander, M., & Shakesheff, K. (2010). Surface Modification of an Injectable Scaffold to Induce osteogenic Differentiation of Human MSC;. In UK National Stem Cell Network. UK National Stem Cell Network.

The development of Small Area Chemically Defined Nano-Arrays for High Throughput Screening: Defining Fundamental Parameters That Can Control Mesenchymal Stem Cell Differentiation at The Nano-Scale (Conference Paper)

Curran, J. M., Chen, R., Hernandez-Santana, A., Graham, D., Amro, N., Sanderin, R., . . . Hunt, J. A. (2010). The development of Small Area Chemically Defined Nano-Arrays for High Throughput Screening: Defining Fundamental Parameters That Can Control Mesenchymal Stem Cell Differentiation at The Nano-Scale. In ESB 2010. Tampere.

2009

Directing Human Adult Stem Cell Function by Molecularly Nanopatterned Surfaces; Introducing Dip Pen Nanolithography® as a Tool for Homogenous Material Driven Cell Responses (Conference Paper)

Curran, J. M., Stokes, R., Irvine, E., Graham, D., Amro, N., Sanderin, R., . . . Hunt, J. A. (2009). Directing Human Adult Stem Cell Function by Molecularly Nanopatterned Surfaces; Introducing Dip Pen Nanolithography® as a Tool for Homogenous Material Driven Cell Responses. In European Society of Biomaterials. Lausanne.

HOMOGENEOUS NANOPATTERNED ARRAYS CONTROL INITIAL ADHESION AND PHENOTYPE IN VITRO; UNLOCKING THE TRUE POTENTIAL OF SMART MATERIALS IN REGENERATIVE MEDICINE (Conference Paper)

Curran, J. M., Stokes, R., Irvine, E., Graham, D., Amro, N., Sanderin, R., . . . Hunt, J. A. (2009). HOMOGENEOUS NANOPATTERNED ARRAYS CONTROL INITIAL ADHESION AND PHENOTYPE IN VITRO; UNLOCKING THE TRUE POTENTIAL OF SMART MATERIALS IN REGENERATIVE MEDICINE. In World Conference on Regenerative Medicine. Leipzig, Germany.

PLGA doping of PCL affects the plastic potential of human mesenchymal stem cells, both in the presence and absence of biological stimuli (Journal article)

Curran, J. M., Tang, Z., & Hunt, J. A. (2009). PLGA doping of PCL affects the plastic potential of human mesenchymal stem cells, both in the presence and absence of biological stimuli. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 89A(1), 1-12. doi:10.1002/jbm.a.31966

DOI: 10.1002/jbm.a.31966

Realising the Potential of Chemically Modified Surfaces for Control of Mesenchymal Stem Cell Functionality Using Homogenous Nanoarrays. (Conference Paper)

Curran, J. M., Stokes, R., Irvine, E., Graham, D., Amro, N., Sanderin, R., . . . Hunt, J. A. (2009). Realising the Potential of Chemically Modified Surfaces for Control of Mesenchymal Stem Cell Functionality Using Homogenous Nanoarrays.. In World Stem Cell Summit. Baltimore USA.

2008

PLGA doping of PCL affects the plastic potential of human mesenchymal stem cells, both in the presence and absence of biological stimuli (Journal article)

Curran, J. M., Tang, Z., & Hunt, J. A. (2008). PLGA doping of PCL affects the plastic potential of human mesenchymal stem cells, both in the presence and absence of biological stimuli. Journal of Biomedical Materials Research Part A, 312, 213-225. Retrieved from doi:%2010.1002/jmb.a.31966

Silane modified tissue engineering substrates induce and maintain human mesenchymal stem cell differentiation (Conference Paper)

Curran, J., Chen, R., & Hunt, J. (2008). Silane modified tissue engineering substrates induce and maintain human mesenchymal stem cell differentiation. In 8th World Biomaterials Congress 2008 Vol. 4 (pp. 2235).

Substrate surface chemistry effects on human mesenchymal stem cell differentiation in 3-D Culture (Conference Paper)

Chen, R., Curran, J. M., & Hunt, J. A. (2008). Substrate surface chemistry effects on human mesenchymal stem cell differentiation in 3-D Culture. In TERMIS-EU 2008 Meeting Vol. 14 (pp. 782). Porto, Potugal: Tissue Engineering: Part A.

The effect of topographical variations of electrostatically spun scaffolds on human mesenchymal stem cell behaviour (Conference Paper)

Curran, J., Andrews, K., & Hunt, J. A. (2008). The effect of topographical variations of electrostatically spun scaffolds on human mesenchymal stem cell behaviour. In 8th World Biomaterials Congress 2008 Vol. 2 (pp. 947).

The potential of PLLA/PLDLA composites as osteoconductive tissue engineering materials (Conference Paper)

Curran, J., & Hunt, J. A. (2008). The potential of PLLA/PLDLA composites as osteoconductive tissue engineering materials. In 8th World Biomaterials Congress 2008 Vol. 2 (pp. 946).

Using Silane Modified Surfaces to Control the Differentiation Pathways of Human MSC (Conference Paper)

Curran, J. M., Chen, R., & Hunt, J. A. (2008). Using Silane Modified Surfaces to Control the Differentiation Pathways of Human MSC. In TERMIS. Porto.

2006

The differentiation of bone marrow mesenchymal stem cells into chondrocyte-like cells on poly-L-lactic acid (PLLA) scaffolds (Journal article)

Richardson, S. M., Curran, J. M., Chen, R., Vaughan-Thomas, A., Hunt, J. A., Freemont, A. J., & Hoyland, J. A. (2006). The differentiation of bone marrow mesenchymal stem cells into chondrocyte-like cells on poly-L-lactic acid (PLLA) scaffolds. BIOMATERIALS, 27(22), 4069-4078. doi:10.1016/j.biomaterials.2006.03.017

DOI: 10.1016/j.biomaterials.2006.03.017

The guidance of human mesenchymal stem cell differentiation in vitro by controlled modifications to the cell substrate (Journal article)

Curran, J. M., Chen, R., & Hunt, J. A. (2006). The guidance of human mesenchymal stem cell differentiation in vitro by controlled modifications to the cell substrate. BIOMATERIALS, 27(27), 4783-4793. doi:10.1016/j.biomaterials.2006.05.001

DOI: 10.1016/j.biomaterials.2006.05.001

The use of poly(L-lactide) and RGD modified microspheres as cell carriers in a flow intermittency bioreactor for tissue engineering cartilage (Journal article)

Chen, R., Curran, S. J., Curran, J. M., & Hunt, J. A. (2006). The use of poly(L-lactide) and RGD modified microspheres as cell carriers in a flow intermittency bioreactor for tissue engineering cartilage. BIOMATERIALS, 27(25), 4453-4460. doi:10.1016/j.biomaterials.2006.04.011

DOI: 10.1016/j.biomaterials.2006.04.011

2005

Controlling the phenotype and function of mesenchymal stem cells in vitro by adhesion to silane-modified clean glass surfaces (Journal article)

Curran, J. M., Chen, R., & Hunt, J. A. (2005). Controlling the phenotype and function of mesenchymal stem cells in vitro by adhesion to silane-modified clean glass surfaces. BIOMATERIALS, 26(34), 7057-7067. doi:10.1016/j.biomaterials.2005.05.008

DOI: 10.1016/j.biomaterials.2005.05.008

Expansion of human chondrocytes in an intermittent stirred flow bioreactor, using modified biodegradable microspheres (Journal article)

Curran, S. J., Chen, R., Curran, J. M., & Hunt, J. A. (2005). Expansion of human chondrocytes in an intermittent stirred flow bioreactor, using modified biodegradable microspheres. TISSUE ENGINEERING, 11(9-10), 1312-1322. doi:10.1089/ten.2005.11.1312

DOI: 10.1089/ten.2005.11.1312

Involvement of adenosine 5'-triphosphate in ultrasound-induced fracture repair. (Journal article)

Hayton, M. J., Dillon, J. P., Glynn, D., Curran, J. M., Gallagher, J. A., & Buckley, K. A. (2005). Involvement of adenosine 5'-triphosphate in ultrasound-induced fracture repair.. Ultrasound in medicine & biology, 31(8), 1131-1138. doi:10.1016/j.ultrasmedbio.2005.04.017

DOI: 10.1016/j.ultrasmedbio.2005.04.017

The inflammatory potential of biphasic calcium phosphate granules in osteoblast/macrophage co-culture (Journal article)

Curran, J. M., Gallagher, J. A., & Hunt, J. A. (2005). The inflammatory potential of biphasic calcium phosphate granules in osteoblast/macrophage co-culture. BIOMATERIALS, 26(26), 5313-5320. doi:10.1016/.jbiomaterials.2005.01.065

DOI: 10.1016/.jbiomaterials.2005.01.065

2004

Surface properties and biocompatibility of solvent-cast poly[epsilon-caprolactone] films (Journal article)

Tang, Z. G., Black, R. A., Curran, J. M., Hunt, J. A., Rhodes, N. P., & Williams, D. F. (2004). Surface properties and biocompatibility of solvent-cast poly[epsilon-caprolactone] films. BIOMATERIALS, 25(19), 4741-4748. doi:10.1016/j.biomaterials.2003.12.003

DOI: 10.1016/j.biomaterials.2003.12.003

2003

Quantitative assessment of the response of primary derived human osteoblasts and macrophages to a range of nanotopography surfaces in a single culture model in vitro (Journal article)

Rice, J. M., Hunt, J. A., Gallagher, J. A., Hanarp, P., Sutherland, D. S., & Gold, J. (2003). Quantitative assessment of the response of primary derived human osteoblasts and macrophages to a range of nanotopography surfaces in a single culture model in vitro. BIOMATERIALS, 24(26), 4799-4818. doi:10.1016/S0142-9612(03)00381-8

DOI: 10.1016/S0142-9612(03)00381-8

Quantitative evaluation of the biocompatible and osteogenic properties of a range of biphasic calcium phosphate (BCP) granules using primary cultures of human osteoblasts and monocytes (Journal article)

Rice, J. M., Hunt, J. A., & Gallagher, J. A. (2003). Quantitative evaluation of the biocompatible and osteogenic properties of a range of biphasic calcium phosphate (BCP) granules using primary cultures of human osteoblasts and monocytes. CALCIFIED TISSUE INTERNATIONAL, 72(6), 726-736. doi:10.1007/s00223-002-2045-y

DOI: 10.1007/s00223-002-2045-y

Release and interconversion of P2 receptor agonists by human osteoblast-like cells. (Journal article)

Buckley, K. A., Golding, S. L., Rice, J. M., Dillon, J. P., & Gallagher, J. A. (2003). Release and interconversion of P2 receptor agonists by human osteoblast-like cells.. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 17(11), 1401-1410. doi:10.1096/fj.02-0940com

DOI: 10.1096/fj.02-0940com

Undated

The development of novel surface modifications for use in a skeletal regeneration system (Thesis / Dissertation)

Fawcett, S. (n.d.). The development of novel surface modifications for use in a skeletal regeneration system. (PhD Thesis, University of Liverpool).
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