Prof Dan Cuthbertson BSc (Hons) PhD FRCP

Reader and Honorary Consultant Physician Musculoskeletal Biology II

    Research

    Research Interest 1

    Insulin resistance, obesity, insulin signalling, AMPK, skeletal muscle, NASH, PCOS, magnetic resonance spectroscopy, MEN

    Research Grants

    Prospective assessment of impact on length of hospital stay, outcome and cost benefit of tolvaptan in patients with aneurysmal subarachnoid haemorrhage with SIADH associated hyponatraemia in a large tertiary neurosurgical centre

    OTSUKA PHARMACEUTICAL EUROPE LTD (UK)

    June 2011 - May 2013

    The effects of exercise training on visceral fat, insulin sensitivity, beta cell function and triglyceride kinetics in patients with non-alcoholic fatty liver disease (NAFLD)

    EUROPEAN FOUNDATION FOR THE STUDY OF DIABETES (GERMANY)

    October 2008 - March 2013

    Characterising the metabolic disruption caused by brief periods of reduced physical activity in people with a family history of type 2 diabetes mellitus (T2DM).

    DIABETES UK (UK)

    March 2014 - December 2017

    The effect of AICAR on skeletal muscle glucose uptake in type 2 diabetes

    PEEL MEDICAL RESEARCH TRUST (UK)

    February 2008 - January 2009

    VIP 2007/08

    WELLCOME TRUST (UK)

    October 2007 - September 2008

    Effects of non-nutritive sweetened (NNS) beverages on appetite during active weight loss: Does the consumption of low calorie sweetened beverages (versus water) support or undermine weight management through effects on hunger, satiety, liking, wanting or changes in food preference?

    AMERICAN BEVERAGE ASSOCIATION (ABA) (USA)

    November 2014 - July 2020

    Zinc-alpha2-glycoprotein (ZAG): A ‘friend or foe’ in obesity-induced insulin resistance and non-alcoholic fatty liver disease (NAFLD)?

    DIABETES RESEARCH AND WELLNESS FOUNDATION (UK)

    June 2010 - May 2011

    Pancreatic and extra-pancreatic effects of glucose-dependent insulinotropic polypeptide (GIP) in humans in health and type 2 diabetes mellitus

    THE NOVO NORDISK UK RESEARCH FOUNDATION (UK)

    May 2010 - April 2012

    Research Collaborations

    Professor Malcolm Jackson

    Internal

    Dr Graham Kemp

    Internal

    Estimation of intrahepatic fat and intramyocellular fat in insulin resistant states

    Professor Paul Trayhurn

    Internal

    Professor John Wilding

    Internal

    Examining aspects of whole body and muscle physiology in obesity

    Dr Martin Lombard

    External: Royal Liverpool and Broadgreen University Hospital NHS Trust

    Involved in investigation into insulin resistance in NASH and hepatitis C

    Professor D.Grahame Hardie

    External: The University of Dundee

    Analysis of AMPK activity

    Dr Calum Sutherland

    External: The University of Dundee

    Molecular biology of insulin resistance

    Professor Michael Rennie

    External: The University of Nottingham

    Examination of muscle protein synthesis