Prof Anne Mcardle BSc (Hons.) PhD

Professor Musculoskeletal Biology II

    Publications

    2018

    Accelerated sarcopenia in Cu/Zn superoxide dismutase knockout mice (Journal article)

    Deepa, S. S., Van Remmen, H., Brooks, S. V., Faulkner, J. A., Larkin, L., McArdle, A., . . . Richardson, A. (2018). Accelerated sarcopenia in Cu/Zn superoxide dismutase knockout mice. Free Radical Biology and Medicine. doi:10.1016/j.freeradbiomed.2018.06.032

    DOI: 10.1016/j.freeradbiomed.2018.06.032

    Developing a toolkit for the assessment and monitoring of musculoskeletal ageing (Journal article)

    Kemp, G. J., Birrell, F., Clegg, P. D., Cuthbertson, D. J., De Vito, G., van Dieen, J. H., . . . Mathers, J. C. (2018). Developing a toolkit for the assessment and monitoring of musculoskeletal ageing. AGE AND AGEING, 47. doi:10.1093/ageing/afy143

    DOI: 10.1093/ageing/afy143

    2017

    'Molecular habituation' as a potential mechanism of gradual homeostatic loss with age (Journal article)

    Guimera, A. M., Welsh, C. M., Proctor, C. J., McArdle, A., & Shanley, D. P. (2018). 'Molecular habituation' as a potential mechanism of gradual homeostatic loss with age. MECHANISMS OF AGEING AND DEVELOPMENT, 169, 53-62. doi:10.1016/j.mad.2017.11.010

    DOI: 10.1016/j.mad.2017.11.010

    A new mouse model of frailty: the Cu/Zn superoxide dismutase knockout mouse (Journal article)

    Deepa, S. S., Bhaskaran, S., Espinoza, S., Brooks, S. V., McArdle, A., Jackson, M. J., . . . Richardson, A. (2017). A new mouse model of frailty: the Cu/Zn superoxide dismutase knockout mouse. GEROSCIENCE, 39(2), 187-198. doi:10.1007/s11357-017-9975-9

    DOI: 10.1007/s11357-017-9975-9

    Comparison of Whole Body SOD1 Knockout with Muscle-Specific SOD1 Knockout Mice Reveals a Role for Nerve Redox Signaling in Regulation of Degenerative Pathways in Skeletal Muscle (Journal article)

    Sakellariou, G. K., McDonagh, B., Porter, H., Giakoumaki, I. I., Earl, K. E., Nye, G. A., . . . Jackson, M. J. (2018). Comparison of Whole Body SOD1 Knockout with Muscle-Specific SOD1 Knockout Mice Reveals a Role for Nerve Redox Signaling in Regulation of Degenerative Pathways in Skeletal Muscle. ANTIOXIDANTS & REDOX SIGNALING, 28(4), 275-295. doi:10.1089/ars.2017.7249

    DOI: 10.1089/ars.2017.7249

    Denervated muscle fibers induce mitochondrial peroxide generation in neighboring innervated fibers: Role in muscle aging (Journal article)

    Pollock, N., Staunton, C. A., Vasilaki, A., McArdle, A., & Jackson, M. J. (2017). Denervated muscle fibers induce mitochondrial peroxide generation in neighboring innervated fibers: Role in muscle aging. FREE RADICAL BIOLOGY AND MEDICINE, 112, 84-92. doi:10.1016/j.freeradbiomed.2017.07.017

    DOI: 10.1016/j.freeradbiomed.2017.07.017

    Role of nerve-muscle interactions and reactive oxygen species in regulation of muscle proteostasis with ageing (Journal article)

    Vasilaki, A., Richardson, A., Van Remmen, H., Brooks, S. V., Larkin, L., McArdle, A., & Jackson, M. J. (2017). Role of nerve-muscle interactions and reactive oxygen species in regulation of muscle proteostasis with ageing. JOURNAL OF PHYSIOLOGY-LONDON, 595(20), 6409-6415. doi:10.1113/JP274336

    DOI: 10.1113/JP274336

    Senescence in the aging process. (Journal article)

    Faragher, R. G., McArdle, A., Willows, A., & Ostler, E. L. (2017). Senescence in the aging process.. F1000Research, 6, 1219. doi:10.12688/f1000research.10903.1

    DOI: 10.12688/f1000research.10903.1

    The role of attenuated redox and heat shock protein responses in the age-related decline in skeletal muscle mass and function. (Journal article)

    McArdle, A., & Jackson, M. J. (2017). The role of attenuated redox and heat shock protein responses in the age-related decline in skeletal muscle mass and function.. Essays in biochemistry, 61(3), 339-348. doi:10.1042/ebc20160088

    DOI: 10.1042/ebc20160088

    Vitamin D status in chronic fatigue syndrome/myalgic encephalomyelitis: a cohort study from the North-West of England (Journal article)

    Earl, K. E., Sakellariou, G. K., Sinclair, M., Fenech, M., Croden, F., Owens, D. J., . . . Beadsworth, M. B. J. (2017). Vitamin D status in chronic fatigue syndrome/myalgic encephalomyelitis: a cohort study from the North-West of England. BMJ OPEN, 7(11). doi:10.1136/bmjopen-2016-015296

    DOI: 10.1136/bmjopen-2016-015296

    2016

    Age-related changes in miR-143-3p:Igfbp5 interactions affect muscle regeneration (Journal article)

    Soriano-Arroquia, A., McCormick, R., Molloy, A. P., McArdle, A., & Goljanek-Whysall, K. (2016). Age-related changes in miR-143-3p:Igfbp5 interactions affect muscle regeneration. AGING CELL, 15(2), 361-369. doi:10.1111/acel.12442

    DOI: 10.1111/acel.12442

    Ageing-induced changes in the redox status of peripheral motor nerves imply an effect on redox signalling rather than oxidative damage (Journal article)

    McDonagh, B., Scullion, S. M., Vasilaki, A., Pollock, N., McArdle, A., & Jackson, M. J. (2016). Ageing-induced changes in the redox status of peripheral motor nerves imply an effect on redox signalling rather than oxidative damage. FREE RADICAL BIOLOGY AND MEDICINE, 94, 27-35. doi:10.1016/j.freeradbiomed.2016.02.008

    DOI: 10.1016/j.freeradbiomed.2016.02.008

    Cellular mechanisms underlying oxidative stress in human exercise (Journal article)

    Jackson, M. J., Vasilaki, A., & McArdle, A. (2016). Cellular mechanisms underlying oxidative stress in human exercise. FREE RADICAL BIOLOGY AND MEDICINE, 98, 13-17. doi:10.1016/j.freeradbiomed.2016.02.023

    DOI: 10.1016/j.freeradbiomed.2016.02.023

    Identification of (poly)phenol treatments that modulate the release of pro-inflammatory cytokines by human lymphocytes (Journal article)

    Ford, C. T., Richardson, S., McArdle, F., Lotito, S. B., Crozier, A., McArdle, A., & Jackson, M. J. (2016). Identification of (poly)phenol treatments that modulate the release of pro-inflammatory cytokines by human lymphocytes. BRITISH JOURNAL OF NUTRITION, 115(10), 1699-1710. doi:10.1017/S0007114516000805

    DOI: 10.1017/S0007114516000805

    Long-term administration of the mitochondria-targeted antioxidant mitoquinone mesylate fails to attenuate age-related oxidative damage or rescue the loss of muscle mass and function associated with aging of skeletal muscle (Journal article)

    Sakellariou, G. K., Pearson, T., Lightfoot, A. P., Nye, G. A., Wells, N., Giakoumaki, I. I., . . . Jackson, M. J. (2016). Long-term administration of the mitochondria-targeted antioxidant mitoquinone mesylate fails to attenuate age-related oxidative damage or rescue the loss of muscle mass and function associated with aging of skeletal muscle. FASEB JOURNAL, 30(11), 3771-3785. doi:10.1096/fj.201600450R

    DOI: 10.1096/fj.201600450R

    Mitochondrial ROS regulate oxidative damage and mitophagy but not age-related muscle fiber atrophy (Journal article)

    Sakellariou, G. K., Pearson, T., Lightfoot, A. P., Nye, G. A., Wells, N., Giakoumaki, I. I., . . . McArdle, A. (2016). Mitochondrial ROS regulate oxidative damage and mitophagy but not age-related muscle fiber atrophy. SCIENTIFIC REPORTS, 6. doi:10.1038/srep33944

    DOI: 10.1038/srep33944

    Role of reactive oxygen species (ROS) in degeneration of ageing muscle (Conference Paper)

    Vasilaki, A., McArdle, A., & Jackson, M. (2016). Role of reactive oxygen species (ROS) in degeneration of ageing muscle. In FREE RADICAL BIOLOGY AND MEDICINE Vol. 96 (pp. S8). doi:10.1016/j.freeradbiomed.2016.04.047

    DOI: 10.1016/j.freeradbiomed.2016.04.047

    Role of reactive oxygen species in age-related neuromuscular deficits (Journal article)

    Jackson, M. J., & McArdle, A. (2016). Role of reactive oxygen species in age-related neuromuscular deficits. JOURNAL OF PHYSIOLOGY-LONDON, 594(8), 1979-1988. doi:10.1113/JP270564

    DOI: 10.1113/JP270564

    The effect of lengthening contractions on neuromuscular junction structure in adult and old mice (Journal article)

    Vasilaki, A., Pollock, N., Giakoumaki, I., Goljanek-Whysall, K., Sakellariou, G. K., Pearson, T., . . . McArdle, A. (2016). The effect of lengthening contractions on neuromuscular junction structure in adult and old mice. AGE, 38(4), 259-272. doi:10.1007/s11357-016-9937-7

    DOI: 10.1007/s11357-016-9937-7

    2015

    Does Manipulation of Environmental Oxygen Modify Reactive Oxygen (ROS) Species Generation During Myogenesis? (Conference Paper)

    McCormick, R., Jackson, M., McArdle, A., & Vasilaki, A. (2015). Does Manipulation of Environmental Oxygen Modify Reactive Oxygen (ROS) Species Generation During Myogenesis?. In FASEB JOURNAL Vol. 29. Retrieved from http://gateway.webofknowledge.com/

    Effect of Muscle Fiber Denervation on Mitochondrial Hydrogen Peroxide Generation in Adjacent Innervated Muscle Fibres: Role in Sarcopenia? (Conference Paper)

    Pollock, N., Vasilaki, A., McArdle, A., & Jackson, M. (2015). Effect of Muscle Fiber Denervation on Mitochondrial Hydrogen Peroxide Generation in Adjacent Innervated Muscle Fibres: Role in Sarcopenia?. In FASEB JOURNAL Vol. 29. Retrieved from http://gateway.webofknowledge.com/

    Effect of Resveratrol on Chemokine Induced Atrophy (Conference Paper)

    McCormick, R., Ford, C., Jackson, M., McArdle, A., & Vasilaki, A. (2015). Effect of Resveratrol on Chemokine Induced Atrophy. In FASEB JOURNAL Vol. 29. Retrieved from http://gateway.webofknowledge.com/

    HEAT SHOCK PROTEIN 70 PROTECTS AGAINST ER STRESS-INDUCED MITOCHONDRIAL DYSFUNCTION; A POTENTIAL THERAPEUTIC TARGET TO REDUCE MUSCLE WEAKNESS IN IIM? (Conference Paper)

    Lightfoot, A. P., Jackson, M. J., McArdle, A., & Cooper, R. G. (2015). HEAT SHOCK PROTEIN 70 PROTECTS AGAINST ER STRESS-INDUCED MITOCHONDRIAL DYSFUNCTION; A POTENTIAL THERAPEUTIC TARGET TO REDUCE MUSCLE WEAKNESS IN IIM?. In RHEUMATOLOGY Vol. 54 (pp. 31-32). Retrieved from http://gateway.webofknowledge.com/

    IS MUSCLE A CHEMOTACTIC ORGAN IN THE IDIOPATHIC INFLAMMATORY MYOPATHIES (IIM)? OVEREXPRESSION OF MHC I (H-2KB) IN C2C12 MYOTUBES RESULTS IN RELEASE OF PRO-NFLAMMATORY CYTOKINES (Conference Paper)

    Lightfoot, A. P., Goljanek-Whysall, K., Cotton, C. V., Earl, K. E., McArdle, A., & Cooper, R. G. (2015). IS MUSCLE A CHEMOTACTIC ORGAN IN THE IDIOPATHIC INFLAMMATORY MYOPATHIES (IIM)? OVEREXPRESSION OF MHC I (H-2KB) IN C2C12 MYOTUBES RESULTS IN RELEASE OF PRO-NFLAMMATORY CYTOKINES. In RHEUMATOLOGY Vol. 54 (pp. 43). Retrieved from http://gateway.webofknowledge.com/

    In the idiopathic inflammatory myopathies (IIM), do reactive oxygen species (ROS) contribute to muscle weakness? (Journal article)

    Lightfoot, A. P., McArdle, A., Jackson, M. J., & Cooper, R. G. (2015). In the idiopathic inflammatory myopathies (IIM), do reactive oxygen species (ROS) contribute to muscle weakness?. ANNALS OF THE RHEUMATIC DISEASES, 74(7), 1340-1346. doi:10.1136/annrheumdis-2014-207172

    DOI: 10.1136/annrheumdis-2014-207172

    In vivo Studies of Motor Nerve Re-growth in Adult and Old Mice Following Contraction-induced Injury (Conference Paper)

    Vasilaki, A., Sakellariou, G., Kayani, A., Jackson, M., & McArdle, A. (2015). In vivo Studies of Motor Nerve Re-growth in Adult and Old Mice Following Contraction-induced Injury. In FASEB JOURNAL Vol. 29. Retrieved from http://gateway.webofknowledge.com/

    Interactions of Short-Term and Chronic Treadmill Training With Aging of the Left Ventricle of the Heart (Journal article)

    Walton, R. D., Jones, S. A., Rostron, K. A., Kayani, A. C., Close, G. L., McArdle, A., & Lancaster, M. K. (2016). Interactions of Short-Term and Chronic Treadmill Training With Aging of the Left Ventricle of the Heart. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES, 71(8), 1005-1013. doi:10.1093/gerona/glv093

    DOI: 10.1093/gerona/glv093

    Investigating the Pathogenic Role of ER Stress Pathway Activation in the Idiopathic Inflammatory Myopathies (IIM): Skeletal Muscle Cells As a Source of Cytokines (Myokines) (Journal article)

    Lightfoot, A. P., Goljanek-Whysall, K., Earl, K. E., Cotton, C. V., McArdle, A., & Cooper, R. G. (2015). Investigating the Pathogenic Role of ER Stress Pathway Activation in the Idiopathic Inflammatory Myopathies (IIM): Skeletal Muscle Cells As a Source of Cytokines (Myokines). ARTHRITIS & RHEUMATOLOGY, 67. Retrieved from http://gateway.webofknowledge.com/

    Investigating the Pathogenic Role of ER Stress Pathways in the Idiopathic Inflammatory Myopathies (IIM): Interrogating the Role of Micro-RNA 133a As an Important Regulator of ER Stress Activation (Journal article)

    Lightfoot, A. P., Goljanek-Whysall, K., McArdle, A., & Cooper, R. G. (2015). Investigating the Pathogenic Role of ER Stress Pathways in the Idiopathic Inflammatory Myopathies (IIM): Interrogating the Role of Micro-RNA 133a As an Important Regulator of ER Stress Activation. ARTHRITIS & RHEUMATOLOGY, 67. Retrieved from http://gateway.webofknowledge.com/

    Manipulation of Environmental Oxygen Modifies Reactive Oxygen Species Generation during Myogenesis (Conference Paper)

    McCormick, R., McArdle, A., Jackson, M., & Vasilaki, A. (2015). Manipulation of Environmental Oxygen Modifies Reactive Oxygen Species Generation during Myogenesis. In FREE RADICAL BIOLOGY AND MEDICINE Vol. 86 (pp. S39-S40). doi:10.1016/j.freeradbiomed.2015.07.137

    DOI: 10.1016/j.freeradbiomed.2015.07.137

    Neuron specific reduction in CuZnSOD is not sufficient to initiate a full sarcopenia phenotype (Journal article)

    Sataranatarajan, K., Qaisar, R., Davis, C., Sakellariou, G. K., Vasilaki, A., Zhang, Y., . . . Van Remmen, H. (2015). Neuron specific reduction in CuZnSOD is not sufficient to initiate a full sarcopenia phenotype. REDOX BIOLOGY, 5, 140-148. doi:10.1016/j.redox.2015.04.005

    DOI: 10.1016/j.redox.2015.04.005

    Neuron specific reduction in CuZnSOD is not sufficient to initiate a full sarcopenia phenotype (Journal article)

    Sataranatarajan, K., Qaisar, R., Davis, C., Sakellariou, G. K., Vasilaki, A., Zhang, Y., . . . Van Remmen, H. (2015). Neuron specific reduction in CuZnSOD is not sufficient to initiate a full sarcopenia phenotype. Redox Biology, 5, 140-148. doi:10.1016/j.redox.2015.04.005

    DOI: 10.1016/j.redox.2015.04.005

    SS-31 attenuates TNF-alpha induced cytokine release from C2C12 myotubes (Journal article)

    Lightfoot, A. P., Sakellariou, G. K., Nye, G. A., McArdle, F., Jackson, M. J., Griffiths, R. D., & McArdle, A. (2015). SS-31 attenuates TNF-alpha induced cytokine release from C2C12 myotubes. REDOX BIOLOGY, 6, 253-259. doi:10.1016/j.redox.2015.08.007

    DOI: 10.1016/j.redox.2015.08.007

    The Impact of a Polyphenol Treatment on TNF-alpha-Induced Cytokine Release from C2C12 Myotubes (Conference Paper)

    Earl, K., Lightfoot, A., & McArdle, A. (2015). The Impact of a Polyphenol Treatment on TNF-alpha-Induced Cytokine Release from C2C12 Myotubes. In FASEB JOURNAL Vol. 29. Retrieved from http://gateway.webofknowledge.com/

    The Role of Cytokines in Muscle Fatigue in Patients with Chronic Fatigue Syndrome (CFS). (Conference Paper)

    Earl, K., Sakellariou, G., Owens, D., Sinclair, M., Fenech, M., Close, G., . . . McArdle, A. (2015). The Role of Cytokines in Muscle Fatigue in Patients with Chronic Fatigue Syndrome (CFS).. In FASEB JOURNAL Vol. 29. Retrieved from http://gateway.webofknowledge.com/

    Understanding the origin of non-immune cell-mediated weakness in the idiopathic inflammatory myopathies - potential role of ER stress pathways (Journal article)

    Lightfoot, A. P., Nagaraju, K., McArdle, A., & Cooper, R. G. (2015). Understanding the origin of non-immune cell-mediated weakness in the idiopathic inflammatory myopathies - potential role of ER stress pathways. CURRENT OPINION IN RHEUMATOLOGY, 27(6), 580-585. doi:10.1097/BOR.0000000000000212

    DOI: 10.1097/BOR.0000000000000212

    2014

    Endoplasmic Reticulum (ER) Stress-Induced Mitochondrial Dysfunction and Atrophy Can be Prevented By Pharmacological Upregulation of Heat Shock Protein 70 (HSP) in Cultured Murine Myotubes. (Journal article)

    Lightfoot, A. P., Jackson, M. J., McArdle, A., & Cooper, R. G. (2014). Endoplasmic Reticulum (ER) Stress-Induced Mitochondrial Dysfunction and Atrophy Can be Prevented By Pharmacological Upregulation of Heat Shock Protein 70 (HSP) in Cultured Murine Myotubes.. ARTHRITIS & RHEUMATOLOGY, 66, S966. Retrieved from http://gateway.webofknowledge.com/

    Lifelong training preserves some redox-regulated adaptive responses after an acute exercise stimulus in aged human skeletal muscle (Journal article)

    Cobley, J. N., Sakellariou, G. K., Owens, D. J., Murray, S., Waldron, S., Gregson, W., . . . Close, G. L. (2014). Lifelong training preserves some redox-regulated adaptive responses after an acute exercise stimulus in aged human skeletal muscle. FREE RADICAL BIOLOGY AND MEDICINE, 70, 23-32. doi:10.1016/j.freeradbiomed.2014.02.004

    DOI: 10.1016/j.freeradbiomed.2014.02.004

    Mechanisms of skeletal muscle ageing; avenues for therapeutic intervention (Journal article)

    Lightfoot, A. P., McCormick, R., Nye, G. A., & McArdle, A. (2014). Mechanisms of skeletal muscle ageing; avenues for therapeutic intervention. CURRENT OPINION IN PHARMACOLOGY, 16, 116-121. doi:10.1016/j.coph.2014.05.005

    DOI: 10.1016/j.coph.2014.05.005

    Mitochondrial ROS generation and function in skeletal muscle from older subjects (Conference Paper)

    Sakellariou, G., Lightfoot, A., Pearson, T., Wells, N., Gilmore, A., Griffiths, R., . . . Jackson, M. (2014). Mitochondrial ROS generation and function in skeletal muscle from older subjects. In FASEB JOURNAL Vol. 28. Retrieved from http://gateway.webofknowledge.com/

    Mitochondrial superoxide mediates TNF-alpha-induced myokine release from C2C12 myotubes (Conference Paper)

    Lightfoot, A., Sakellariou, G., Nye, G., McArdle, F., Jackson, M., Griffiths, R., & McArdle, A. (2014). Mitochondrial superoxide mediates TNF-alpha-induced myokine release from C2C12 myotubes. In FASEB JOURNAL Vol. 28. Retrieved from http://gateway.webofknowledge.com/

    Musculoskeletal changes in superoxide dismutase 1 null mice (Conference Paper)

    Nye, G., Lightfoot, A., Sakellariou, G., Boudiffa, M., Bellantuono, I., Brooks, S., . . . McArdle, A. (2014). Musculoskeletal changes in superoxide dismutase 1 null mice. In FASEB JOURNAL Vol. 28. Retrieved from http://gateway.webofknowledge.com/

    Neuron-specific expression of CuZnSOD prevents the loss of muscle mass and function that occurs in homozygous CuZnSOD-knockout mice (Journal article)

    Sakellariou, G. K., Davis, C. S., Shi, Y., Ivannikov, M. V., Zhang, Y., Vasilaki, A., . . . Brooks, S. V. (2014). Neuron-specific expression of CuZnSOD prevents the loss of muscle mass and function that occurs in homozygous CuZnSOD-knockout mice. FASEB JOURNAL, 28(4), 1666-1681. doi:10.1096/fj.13-240390

    DOI: 10.1096/fj.13-240390

    Nitric oxide availability is increased in contracting skeletal muscle from aged mice, but does not differentially decrease muscle superoxide (Journal article)

    Pearson, T., McArdle, A., & Jackson, M. J. (2015). Nitric oxide availability is increased in contracting skeletal muscle from aged mice, but does not differentially decrease muscle superoxide. FREE RADICAL BIOLOGY AND MEDICINE, 78, 82-88. doi:10.1016/j.freeradbiomed.2014.10.505

    DOI: 10.1016/j.freeradbiomed.2014.10.505

    Skeletal Muscle Contractions Induce Acute Changes in Cytosolic Superoxide, but Slower Responses in Mitochondrial Superoxide and Cellular Hydrogen Peroxide (Journal article)

    Pearson, T., Kabayo, T., Ng, R., Chamberlain, J., McArdle, A., & Jackson, M. J. (2014). Skeletal Muscle Contractions Induce Acute Changes in Cytosolic Superoxide, but Slower Responses in Mitochondrial Superoxide and Cellular Hydrogen Peroxide. PLOS ONE, 9(5). doi:10.1371/journal.pone.0096378

    DOI: 10.1371/journal.pone.0096378

    2013

    Aging increases the oxidation of dichlorohydrofluorescein in single isolated skeletal muscle fibers at rest, but not during contractions (Journal article)

    Palomero, J., Vasilaki, A., Pye, D., McArdle, A., & Jackson, M. J. (2013). Aging increases the oxidation of dichlorohydrofluorescein in single isolated skeletal muscle fibers at rest, but not during contractions. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY, 305(4), R351-R358. doi:10.1152/ajpregu.00530.2012

    DOI: 10.1152/ajpregu.00530.2012

    CuZnSOD gene deletion targeted to skeletal muscle leads to loss of contractile force but does not cause muscle atrophy in adult mice (Journal article)

    Zhang, Y., Davis, C., Sakellariou, G. K., Shi, Y., Kayani, A. C., Pulliam, D., . . . Van Remmen, H. (2013). CuZnSOD gene deletion targeted to skeletal muscle leads to loss of contractile force but does not cause muscle atrophy in adult mice. FASEB JOURNAL, 27(9), 3536-3548. doi:10.1096/fj.13-228130

    DOI: 10.1096/fj.13-228130

    CuZnSOD gene deletion targeted to skeletal muscle leads to loss of contractile force but does not cause muscle atrophy in adult mice (Journal article)

    Zhang, Y., Davis, C., Sakellariou, G. K., Shi, Y., Kayani, A. C., Pulliam, D., . . . Van Remmen, H. (2013). CuZnSOD gene deletion targeted to skeletal muscle leads to loss of contractile force but does not cause muscle atrophy in adult mice. The FASEB Journal, 27(9), 3536-3548. doi:10.1096/fj.13-228130

    DOI: 10.1096/fj.13-228130

    Shared Ageing Research Models (ShARM): a new facility to support ageing research. (Journal article)

    Duran, A. L., Potter, P., Wells, S., Kirkwood, T., von Zglinicki, T., McArdle, A., . . . Bellantuono, I. (2013). Shared Ageing Research Models (ShARM): a new facility to support ageing research.. Biogerontology, 14(6), 789-794. doi:10.1007/s10522-013-9457-0

    DOI: 10.1007/s10522-013-9457-0

    Studies of Mitochondrial and Nonmitochondrial Sources Implicate Nicotinamide Adenine Dinucleotide Phosphate Oxidase(s) in the Increased Skeletal Muscle Superoxide Generation That Occurs During Contractile Activity (Journal article)

    Sakellariou, G. K., Vasilaki, A., Palomero, J., Kayani, A., Zibrik, L., McArdle, A., & Jackson, M. J. (2013). Studies of Mitochondrial and Nonmitochondrial Sources Implicate Nicotinamide Adenine Dinucleotide Phosphate Oxidase(s) in the Increased Skeletal Muscle Superoxide Generation That Occurs During Contractile Activity. ANTIOXIDANTS & REDOX SIGNALING, 18(6), 603-621. doi:10.1089/ars.2012.4623

    DOI: 10.1089/ars.2012.4623

    2012

    Workshop report: Can an understanding of the mechanisms underlying age-related loss of muscle mass and function guide exercise and other intervention strategies? (Journal article)

    Jackson, M. J., McArdle, A., Vasilaki, A., & Kayani, A. (2012). Workshop report: Can an understanding of the mechanisms underlying age-related loss of muscle mass and function guide exercise and other intervention strategies?. Longevity & healthspan, 1, 5. doi:10.1186/2046-2395-1-5

    DOI: 10.1186/2046-2395-1-5

    2011

    Age-related changes in skeletal muscle reactive oxygen species generation and adaptive responses to reactive oxygen species (Journal article)

    Jackson, M. J., & McArdle, A. (2011). Age-related changes in skeletal muscle reactive oxygen species generation and adaptive responses to reactive oxygen species. JOURNAL OF PHYSIOLOGY-LONDON, 589(9), 2139-2145. doi:10.1113/jphysiol.2011.206623

    DOI: 10.1113/jphysiol.2011.206623

    Gathering insights on disease etiology from gene expression profiles of healthy tissues (Journal article)

    Silva, A. S., Wood, S. H., van Dam, S., Berres, S., McArdle, A., & de Magalhaes, J. P. (2011). Gathering insights on disease etiology from gene expression profiles of healthy tissues. BIOINFORMATICS, 27(23), 3300-3305. doi:10.1093/bioinformatics/btr559

    DOI: 10.1093/bioinformatics/btr559

    Gathering insights on disease etiology from gene expression profiles of healthy tissues (Journal article)

    Silva, A. S., Wood, S. H., van Dam, S., Berres, S., McArdle, A., & de Magalhães, J. P. (2011). Gathering insights on disease etiology from gene expression profiles of healthy tissues. Bioinformatics, 27, 3300-3305.

    Reactive oxygen species generation and skeletal muscle wasting - Implications for sarcopenia (Chapter)

    McArdle, A., & Jackson, M. J. (2011). Reactive oxygen species generation and skeletal muscle wasting - Implications for sarcopenia. In Sarcopenia - Age-Related Muscle Wasting and Weakness: Mechanisms and Treatments (pp. 317-331). doi:10.1007/978-90-481-9713-2_14

    DOI: 10.1007/978-90-481-9713-2_14

    Role of superoxide-nitric oxide interactions in the accelerated age-related loss of muscle mass in mice lacking Cu,Zn superoxide dismutase (Journal article)

    Sakellariou, G. K., Pye, D., Vasilaki, A., Zibrik, L., Palomero, J., Kabayo, T., . . . Jackson, M. J. (2011). Role of superoxide-nitric oxide interactions in the accelerated age-related loss of muscle mass in mice lacking Cu,Zn superoxide dismutase. AGING CELL, 10(5), 749-760. doi:10.1111/j.1474-9726.2011.00709.x

    DOI: 10.1111/j.1474-9726.2011.00709.x

    The effects of L-NAME on neuronal NOS and SOD1 expression in the DRG-spinal cord network of axotomised Thy 1.2 eGFP mice. (Journal article)

    Bradman, M. J. G., Morris, R., McArdle, A., Jackson, M. J., & Thippeswamy, T. (2011). The effects of L-NAME on neuronal NOS and SOD1 expression in the DRG-spinal cord network of axotomised Thy 1.2 eGFP mice.. Neuron glia biology, 7(2-4), 129-141. doi:10.1017/s1740925x12000051

    DOI: 10.1017/s1740925x12000051

    2010

    Absence of insulin signalling in skeletal muscle is associated with reduced muscle mass and function: evidence for decreased protein synthesis and not increased degradation (Journal article)

    O'Neill, E. D., Wilding, J. P. H., Kahn, C. R., Van Remmen, H., McArdle, A., Jackson, M. J., & Close, G. L. (2010). Absence of insulin signalling in skeletal muscle is associated with reduced muscle mass and function: evidence for decreased protein synthesis and not increased degradation. AGE, 32(2), 209-222. doi:10.1007/s11357-009-9125-0

    DOI: 10.1007/s11357-009-9125-0

    Effect of xanthine oxidase-generated extracellular superoxide on skeletal muscle force generation (Journal article)

    Gomez-Cabrera, M. C., Close, G. L., Kayani, A., McArdle, A., Vina, J., & Jackson, M. J. (2010). Effect of xanthine oxidase-generated extracellular superoxide on skeletal muscle force generation. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY, 298(1), R2-R8. doi:10.1152/ajpregu.00142.2009

    DOI: 10.1152/ajpregu.00142.2009

    Overexpression of HSP10 in skeletal muscle of transgenic mice prevents the age-related fall in maximum tetanic force generation and muscle cross-sectional area (Journal article)

    Kayani, A. C., Close, G. L., Dillmann, W. H., Mestril, R., Jackson, M. J., & McArdle, A. (2010). Overexpression of HSP10 in skeletal muscle of transgenic mice prevents the age-related fall in maximum tetanic force generation and muscle cross-sectional area. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY, 299(1), R268-R276. doi:10.1152/ajpregu.00334.2009

    DOI: 10.1152/ajpregu.00334.2009

    The age-related failure of adaptive responses to contractile activity in skeletal muscle is mimicked in young mice by deletion of Cu,Zn superoxide dismutase (Journal article)

    Vasilaki, A., van der Meulen, J. H., Larkin, L., Harrison, D. C., Pearson, T., Van Remmen, H., . . . McArdle, A. (2010). The age-related failure of adaptive responses to contractile activity in skeletal muscle is mimicked in young mice by deletion of Cu,Zn superoxide dismutase. AGING CELL, 9(6), 979-990. doi:10.1111/j.1474-9726.2010.00635.x

    DOI: 10.1111/j.1474-9726.2010.00635.x

    The age-related failure of adaptive responses to contractile activity in skeletal muscle is mimicked in young mice by deletion of Cu,Zn superoxide dismutase (Journal article)

    Vasilaki, A., van der Meulen, J. H., Larkin, L., Harrison, D. C., Pearson, T., Van Remmen, H., . . . McArdle, A. (2010). The age-related failure of adaptive responses to contractile activity in skeletal muscle is mimicked in young mice by deletion of Cu,Zn superoxide dismutase. Aging Cell, 9(6), 979-990. doi:10.1111/j.1474-9726.2010.00635.x

    DOI: 10.1111/j.1474-9726.2010.00635.x

    2009

    Exercise training-induced gender-specific heat shock protein adaptations in human skeletal muscle. (Journal article)

    Morton, J. P., Holloway, K., Woods, P., Cable, N. T., Burniston, J., Evans, L., . . . McArdle, A. (2009). Exercise training-induced gender-specific heat shock protein adaptations in human skeletal muscle.. Muscle & nerve, 39(2), 230-233. doi:10.1002/mus.21182

    DOI: 10.1002/mus.21182

    Muscle in defense. (Journal article)

    Lightfoot, A., McArdle, A., & Griffiths, R. D. (2009). Muscle in defense.. Critical care medicine, 37(10 Suppl), S384-S390. doi:10.1097/ccm.0b013e3181b6f8a5

    DOI: 10.1097/ccm.0b013e3181b6f8a5

    Reduced carbohydrate availability does not modulate training-induced heat shock protein adaptations but does upregulate oxidative enzyme activity in human skeletal muscle. (Journal article)

    Morton, J. P., Croft, L., Bartlett, J. D., Maclaren, D. P. M., Reilly, T., Evans, L., . . . Drust, B. (2009). Reduced carbohydrate availability does not modulate training-induced heat shock protein adaptations but does upregulate oxidative enzyme activity in human skeletal muscle.. Journal of applied physiology (Bethesda, Md. : 1985), 106(5), 1513-1521. doi:10.1152/japplphysiol.00003.2009

    DOI: 10.1152/japplphysiol.00003.2009

    The exercise-induced stress response of skeletal muscle, with specific emphasis on humans. (Journal article)

    Morton, J. P., Kayani, A. C., McArdle, A., & Drust, B. (2009). The exercise-induced stress response of skeletal muscle, with specific emphasis on humans.. Sports medicine (Auckland, N.Z.), 39(8), 643-662. doi:10.2165/00007256-200939080-00003

    DOI: 10.2165/00007256-200939080-00003

    2008

    Enhanced Recovery from Contraction-Induced Damage in Skeletal Muscles of Old Mice Following Treatment with the Heat Shock Protein Inducer 17-(Allylamino)-17-Demethoxygeldanamycin (Journal article)

    Kayani, A. C., Close, G. L., Broome, C. S., Jackson, M. J., & McArdle, A. (2008). Enhanced Recovery from Contraction-Induced Damage in Skeletal Muscles of Old Mice Following Treatment with the Heat Shock Protein Inducer 17-(Allylamino)-17-Demethoxygeldanamycin. REJUVENATION RESEARCH, 11(6), 1021-1030. doi:10.1089/rej.2008.0795

    DOI: 10.1089/rej.2008.0795

    Heat shock factor activation in human muscles following a demanding intermittent exercise protocol is attenuated with hyperthermia. (Journal article)

    Palomero, J., Broome, C. S., Rasmussen, P., Mohr, M., Nielsen, B., Nybo, L., . . . Drust, B. (2008). Heat shock factor activation in human muscles following a demanding intermittent exercise protocol is attenuated with hyperthermia.. Acta physiologica (Oxford, England), 193(1), 79-88. doi:10.1111/j.1748-1716.2007.01774.x

    DOI: 10.1111/j.1748-1716.2007.01774.x

    Prolonged treadmill training increases HSP70 in skeletal muscle but does not affect age-related functional deficits (Journal article)

    Kayani, A. C., Close, G. L., Jackson, M. J., & McArdle, A. (2008). Prolonged treadmill training increases HSP70 in skeletal muscle but does not affect age-related functional deficits. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY, 294(2), R568-R576. doi:10.1152/ajpregu.00575.2007

    DOI: 10.1152/ajpregu.00575.2007

    Repeated bouts of aerobic exercise lead to reductions in skeletal muscle free radical generation and nuclear factor kappa B activation (Journal article)

    Brooks, S. V., Vasilaki, A., Larkin, L. M., McArdle, A., & Jackson, M. J. (2008). Repeated bouts of aerobic exercise lead to reductions in skeletal muscle free radical generation and nuclear factor kappa B activation. JOURNAL OF PHYSIOLOGY-LONDON, 586(16), 3979-3990. doi:10.1113/jphysiol.2008.155382

    DOI: 10.1113/jphysiol.2008.155382

    The exercise-induced stress response in skeletal muscle: failure during aging. (Journal article)

    Kayani, A. C., Morton, J. P., & McArdle, A. (2008). The exercise-induced stress response in skeletal muscle: failure during aging.. Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 33(5), 1033-1041. doi:10.1139/h08-089

    DOI: 10.1139/h08-089

    Trained men display increased basal heat shock protein content of skeletal muscle. (Journal article)

    Morton, J. P., Maclaren, D. P. M., Cable, N. T., Campbell, I. T., Evans, L., Kayani, A. C., . . . Drust, B. (2008). Trained men display increased basal heat shock protein content of skeletal muscle.. Medicine and science in sports and exercise, 40(7), 1255-1262. doi:10.1249/mss.0b013e31816a7171

    DOI: 10.1249/mss.0b013e31816a7171

    2007

    Elevated core and muscle temperature to levels comparable to exercise do not increase heat shock protein content of skeletal muscle of physically active men (Journal article)

    Morton, J. P., MacLaren, D. P. M., Cable, N. T., Campbell, I. T., Evans, L., Bongers, T., . . . Drust, B. (2007). Elevated core and muscle temperature to levels comparable to exercise do not increase heat shock protein content of skeletal muscle of physically active men. Acta Physiologica, 190(4), 319-327. doi:10.1111/j.1748-1716.2007.01711.x

    DOI: 10.1111/j.1748-1716.2007.01711.x

    Elevated core and muscle temperature to levels comparable to exercise do not increase heat shock protein content of skeletal muscle of physically active men. (Journal article)

    Morton, J. P., Maclaren, D. P. M., Cable, N. T., Campbell, I. T., Evans, L., Bongers, T., . . . Drust, B. (2007). Elevated core and muscle temperature to levels comparable to exercise do not increase heat shock protein content of skeletal muscle of physically active men.. Acta physiologica (Oxford, England), 190(4), 319-327. doi:10.1111/j.1748-1716.2007.01711.x

    DOI: 10.1111/j.1748-1716.2007.01711.x

    Exogenous glutamine: the clinical evidence. (Journal article)

    Bongers, T., Griffiths, R. D., & McArdle, A. (2007). Exogenous glutamine: the clinical evidence.. Critical care medicine, 35(9 Suppl), S545-S552. doi:10.1097/01.ccm.0000279193.23737.06

    DOI: 10.1097/01.ccm.0000279193.23737.06

    Formation of 3-nitrotyrosines in carbonic anhydrase III is a sensitive marker of oxidative stress in skeletal muscle (Journal article)

    Vasilaki, A., Simpson, D., McArdle, F., McLean, L., Beynon, R. J., Van Remmen, H., . . . Jackson, M. J. (2007). Formation of 3-nitrotyrosines in carbonic anhydrase III is a sensitive marker of oxidative stress in skeletal muscle. PROTEOMICS CLINICAL APPLICATIONS, 1(4), 362-372. doi:10.1002/prca.200600702

    DOI: 10.1002/prca.200600702

    Formation of 3-nitrotyrosines in carbonic anhydrase III is a sensitive marker of oxidative stress in skeletal muscle (Journal article)

    Vasilaki, A., Simpson, D., McArdle, F., McLean, L., Beynon, R. J., Van Remmen, H., . . . Jackson, M. J. (2007). Formation of 3-nitrotyrosines in carbonic anhydrase III is a sensitive marker of oxidative stress in skeletal muscle. PROTEOMICS – Clinical Applications, 1(4), 362-372. doi:10.1002/prca.200600702

    DOI: 10.1002/prca.200600702

    Markers of oxidative stress in the skeletal muscle of patients on haemodialysis (Journal article)

    Crowe, A. V., McArdle, A., McArdle, F., Pattwell, D. M., Bell, G. M., Kemp, G. J., . . . Jackson, M. J. (2007). Markers of oxidative stress in the skeletal muscle of patients on haemodialysis. NEPHROLOGY DIALYSIS TRANSPLANTATION, 22(4), 1177-1183. doi:10.1093/ndt/gfl721

    DOI: 10.1093/ndt/gfl721

    Release of superoxide from skeletal muscle of adult and old mice: an experimental test of the reductive hotspot hypothesis (Journal article)

    Close, G. L., Kayani, A. C., Ashton, T., McArdle, A., & Jackson, M. J. (2007). Release of superoxide from skeletal muscle of adult and old mice: an experimental test of the reductive hotspot hypothesis. AGING CELL, 6(2), 189-195. doi:10.1111/j.1474-9726.2007.00277.x

    DOI: 10.1111/j.1474-9726.2007.00277.x

    Skeletal Muscle (Chapter)

    Griffiths, R. D., Bongers, T., & McArdle, A. (2007). Skeletal Muscle. In E. Abraham, & M. Singer (Eds.), Mechanisms of Sepsis-induced organ dysfunction and recovery (Vol. 44, pp. 437-447). Berlin: Springer-Verlag.

    Skeletal muscle aging (Journal article)

    Close, G. L., Haggan, P., & McArdle, A. (2007). Skeletal muscle aging. Reviews in Clinical Gerontology, 17(01). doi:10.1017/S0959259808002360

    DOI: 10.1017/S0959259808002360

    The role of hormones, cytokines and heat shock proteins during age-related muscle loss. (Journal article)

    Lee, C. E., McArdle, A., & Griffiths, R. D. (2007). The role of hormones, cytokines and heat shock proteins during age-related muscle loss.. Clinical nutrition (Edinburgh, Scotland), 26(5), 524-534. doi:10.1016/j.clnu.2007.05.005

    DOI: 10.1016/j.clnu.2007.05.005

    Time-course and differential expression of heat shock proteins in human skeletal muscle following non-damaging treadmill exercise: is heat a mechanism of activation? (Journal article)

    Morton, J., MacLaren, D., McArdle, A., & Drust, B. (2007). Time-course and differential expression of heat shock proteins in human skeletal muscle following non-damaging treadmill exercise: is heat a mechanism of activation?. Japanese Journal of Physical Fitness and Sports Medicine, 56(1), 36. doi:10.7600/jspfsm.56.36

    DOI: 10.7600/jspfsm.56.36

    2006

    Adaptive responses of mouse skeletal muscle to contractile activity: The effect of age (Journal article)

    Vasilaki, A., McArdle, F., Iwanejko, L. M., & McArdle, A. (2006). Adaptive responses of mouse skeletal muscle to contractile activity: The effect of age. MECHANISMS OF AGEING AND DEVELOPMENT, 127(11), 830-839. doi:10.1016/j.mad.2006.08.004

    DOI: 10.1016/j.mad.2006.08.004

    Alcohol alters skeletal muscle heat shock protein gene expression in rats: these effects are moderated by sex, raised endogenous acetaldehyde, and starvation. (Journal article)

    Nakahara, T., Hunter, R., Hirano, M., Uchimura, H., McArdle, A., Broome, C. S., . . . Preedy, V. R. (2006). Alcohol alters skeletal muscle heat shock protein gene expression in rats: these effects are moderated by sex, raised endogenous acetaldehyde, and starvation.. Metabolism: clinical and experimental, 55(7), 843-851. doi:10.1016/j.metabol.2006.02.009

    DOI: 10.1016/j.metabol.2006.02.009

    Effect of lifelong overexpression of HSP70 in skeletal muscle on age-related oxidative stress and adaptation after nondamaging contractile activity (Journal article)

    Broome, C. S., Kayani, A. C., Palomero, J., Dillmann, W. H., Mestril, R., Jackson, M. J., & McArdle, A. (2006). Effect of lifelong overexpression of HSP70 in skeletal muscle on age-related oxidative stress and adaptation after nondamaging contractile activity. FASEB JOURNAL, 20(9), 1549-+. doi:10.1096/fj.05-4935fje

    DOI: 10.1096/fj.05-4935fje

    Free radical generation by skeletal muscle of adult and old mice: effect of contractile activity (Journal article)

    Vasilaki, A., Mansouri, A., Van Remmen, H., van der Meulen, J. H., Larkin, L., Richardson, A. G., . . . Jackson, M. J. (2006). Free radical generation by skeletal muscle of adult and old mice: effect of contractile activity. AGING CELL, 5(2), 109-117. doi:10.1111/j.1474-9726.2006.00198.x

    DOI: 10.1111/j.1474-9726.2006.00198.x

    Genetic modification of the manganese superoxide dismutase/glutathione peroxidase 1 pathway influences intracellular ROS generation in quiescent, but not contracting, skeletal muscle cells (Journal article)

    Vasilaki, A., Csete, M., Pye, D., Lee, S., Palomero, J., McArdle, F., . . . Jackson, M. J. (2006). Genetic modification of the manganese superoxide dismutase/glutathione peroxidase 1 pathway influences intracellular ROS generation in quiescent, but not contracting, skeletal muscle cells. FREE RADICAL BIOLOGY AND MEDICINE, 41(11), 1719-1725. doi:10.1016/j.freeradbiomed.2006.09.008

    DOI: 10.1016/j.freeradbiomed.2006.09.008

    HSF expression in skeletal muscle during myogenesis: Implications for failed regeneration in old mice (Journal article)

    McArdle, A., Broome, C. S., Kayani, A. C., Tully, M. D., Close, G. L., Vasilaki, A., & Jackson, M. J. (2006). HSF expression in skeletal muscle during myogenesis: Implications for failed regeneration in old mice. EXPERIMENTAL GERONTOLOGY, 41(5), 497-500. doi:10.1016/j.exger.2006.02.002

    DOI: 10.1016/j.exger.2006.02.002

    Time course and differential responses of the major heat shock protein families in human skeletal muscle following acute nondamaging treadmill exercise. (Journal article)

    Morton, J. P., MacLaren, D. P. M., Cable, N. T., Bongers, T., Griffiths, R. D., Campbell, I. T., . . . Drust, B. (2006). Time course and differential responses of the major heat shock protein families in human skeletal muscle following acute nondamaging treadmill exercise.. Journal of applied physiology (Bethesda, Md. : 1985), 101(1), 176-182. doi:10.1152/japplphysiol.00046.2006

    DOI: 10.1152/japplphysiol.00046.2006

    2005

    Intracellular generation of reactive oxygen species by contracting skeletal muscle cells (Journal article)

    McArdle, F., Pattwell, D. M., Vasilaki, A., McArdle, A., & Jackson, M. J. (2005). Intracellular generation of reactive oxygen species by contracting skeletal muscle cells. FREE RADICAL BIOLOGY AND MEDICINE, 39(5), 651-657. doi:10.1016/j.freeradbiomed.2005.04.010

    DOI: 10.1016/j.freeradbiomed.2005.04.010

    Microdialysis studies of extracellular reactive oxygen species in skeletal muscle: Factors influencing the reduction of cytochrome c and hydroxylation of salicylate (Journal article)

    Close, G. L., Ashton, T., McArdle, A., & Jackson, M. J. (2005). Microdialysis studies of extracellular reactive oxygen species in skeletal muscle: Factors influencing the reduction of cytochrome c and hydroxylation of salicylate. FREE RADICAL BIOLOGY AND MEDICINE, 39(11), 1460-1467. doi:10.1016/j.freeradbiomed.2005.07.009

    DOI: 10.1016/j.freeradbiomed.2005.07.009

    Reliability of maximal muscle force and voluntary activation as markers of exercise-induced muscle damage. (Journal article)

    Morton, J. P., Atkinson, G., MacLaren, D. P., Cable, N. T., Gilbert, G., Broome, C., . . . Drust, B. (2005). Reliability of maximal muscle force and voluntary activation as markers of exercise-induced muscle damage.. European journal of applied physiology, 94(5-6), 541-548. doi:10.1007/s00421-005-1373-9

    DOI: 10.1007/s00421-005-1373-9

    Skeletal muscle damage with exercise and aging (Journal article)

    Close, G. L., Kayani, A., Vasilaki, A., & McArdle, A. (2005). Skeletal muscle damage with exercise and aging. SPORTS MEDICINE, 35(5), 413-427. doi:10.2165/00007256-200535050-00004

    DOI: 10.2165/00007256-200535050-00004

    The emerging role of free radicals in delayed onset muscle soreness and contraction-induced muscle injury. (Journal article)

    Close, G. L., Ashton, T., McArdle, A., & Maclaren, D. P. M. (2005). The emerging role of free radicals in delayed onset muscle soreness and contraction-induced muscle injury.. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 142(3), 257-266. doi:10.1016/j.cbpa.2005.08.005

    DOI: 10.1016/j.cbpa.2005.08.005

    2004

    Are there functional consequences of a reduction in selenium intake in UK subjects? (Journal article)

    Jackson, M. J., Dillon, S. A., Broome, C. S., McArdle, A., Hart, C. A., & McArdle, F. (2004). Are there functional consequences of a reduction in selenium intake in UK subjects?. PROCEEDINGS OF THE NUTRITION SOCIETY, 63(4), 513-517. doi:10.1079/PNS2004382

    DOI: 10.1079/PNS2004382

    Keeping up the defenses. (Journal article)

    Griffiths, R. D., & McArdle, A. (2004). Keeping up the defenses.. Nutrition (Burbank, Los Angeles County, Calif.), 20(6), 587-589. doi:10.1016/j.nut.2004.03.015

    DOI: 10.1016/j.nut.2004.03.015

    Overexpression of HSP70 in mouse skeletal muscle protects against muscle damage and age-related muscle dysfunction (Journal article)

    McArdle, A., Dillmann, W. H., Mestril, R., Faulkner, J. A., & Jackson, M. J. (2003). Overexpression of HSP70 in mouse skeletal muscle protects against muscle damage and age-related muscle dysfunction. FASEB JOURNAL, 17(15), 355-+. doi:10.1096/fj.03-0395fje

    DOI: 10.1096/fj.03-0395fje

    Overexpression of HSP70 in mouse skeletal muscle protects against muscle damage and age-related muscle dysfunction. (Journal article)

    McArdle, A., Dillmann, W. H., Mestril, R., Faulkner, J. A., & Jackson, M. J. (2004). Overexpression of HSP70 in mouse skeletal muscle protects against muscle damage and age-related muscle dysfunction.. The FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 18(2), 355-357.

    Preconditioning of skeletal muscle against contraction-induced damage: the role of adaptations to oxidants in mice (Journal article)

    McArdle, F., Spiers, S., Aldemir, H., Vasilaki, A., Beaver, A., Iwanejko, L., . . . Jackson, M. J. (2004). Preconditioning of skeletal muscle against contraction-induced damage: the role of adaptations to oxidants in mice. JOURNAL OF PHYSIOLOGY-LONDON, 561(1), 233-244. doi:10.1113/jphysiol.2004.069914

    DOI: 10.1113/jphysiol.2004.069914

    Release of reactive oxygen and nitrogen species from contracting skeletal muscle cells (Journal article)

    Patwell, D. M., McArdle, A., Morgan, J. E., Patridge, T. A., & Jackson, M. J. (2004). Release of reactive oxygen and nitrogen species from contracting skeletal muscle cells. FREE RADICAL BIOLOGY AND MEDICINE, 37(7), 1064-1072. doi:10.1016/j.freeradbiomed.2004.06.026

    DOI: 10.1016/j.freeradbiomed.2004.06.026

    Release of reactive oxygen and nitrogen species from contracting skeletal muscle cells (vol 37, pg 1064, 2004) (Journal article)

    Pattwell, D. M., McArdle, A., Morgan, J. E., Patridge, T. A., & Jackson, M. J. (2004). Release of reactive oxygen and nitrogen species from contracting skeletal muscle cells (vol 37, pg 1064, 2004). FREE RADICAL BIOLOGY AND MEDICINE, 37(12), 2083. doi:10.1016/j.freeradbiomed.2004.09.019

    DOI: 10.1016/j.freeradbiomed.2004.09.019

    Role of mitochondrial superoxide dismutase in contraction-induced generation of reactive oxygen species in skeletal muscle extracellular space (Journal article)

    McArdle, A., van der Meulen, J., Close, G. L., Pattwell, D., Van Remmen, H., Huang, T. T., . . . Jackson, M. J. (2004). Role of mitochondrial superoxide dismutase in contraction-induced generation of reactive oxygen species in skeletal muscle extracellular space. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 286(5), C1152-C1158. doi:10.1152/ajpcell.00322.2003

    DOI: 10.1152/ajpcell.00322.2003

    Vitamin E and the oxidative stress of exercise (Journal article)

    Jackson, M. J., Khassaf, M., Vasilaki, A., McArdle, F., & McArdle, A. (2004). Vitamin E and the oxidative stress of exercise. VITAMIN E AND HEALTH, 1031, 158-168. doi:10.1196/annals.1331.015

    DOI: 10.1196/annals.1331.015

    2003

    Damage to developing mouse skeletal muscle myotubes in culture: protective effect of heat shock proteins (Journal article)

    Maglara, A. A., Vasilaki, A., Jackson, M. J., & McArdle, A. (2003). Damage to developing mouse skeletal muscle myotubes in culture: protective effect of heat shock proteins. Journal of Physiology, 548(3), 837-846. doi:10.1111/j.1469-7793.2003.00837.x

    DOI: 10.1111/j.1469-7793.2003.00837.x

    Damage to developing mouse skeletal muscle myotubes in culture: protective effect of heat shock proteins (Journal article)

    Maglara, A. A., Vasilaki, A., Jackson, M. J., & McArdle, A. (2003). Damage to developing mouse skeletal muscle myotubes in culture: protective effect of heat shock proteins. JOURNAL OF PHYSIOLOGY-LONDON, 548(3), 837-846. doi:10.1113/jphysiol.2002.034520

    DOI: 10.1113/jphysiol.2002.034520

    Effect of vitamin C supplements on antioxidant defence and stress proteins in human lymphocytes and skeletal muscle (Journal article)

    Khassaf, M., McArdle, A., Esanu, C., Vasilaki, A., McArdle, F., Griffiths, R. D., . . . Jackson, M. J. (2003). Effect of vitamin C supplements on antioxidant defence and stress proteins in human lymphocytes and skeletal muscle. JOURNAL OF PHYSIOLOGY-LONDON, 549(2), 645-652. doi:10.1113/jphysiol.2003.040303

    DOI: 10.1113/jphysiol.2003.040303

    Effect of vitamin C supplements on antioxidant defence and stress proteins in human lymphocytes and skeletal muscle (Journal article)

    Khassaf, M., McArdle, A., Esanu, C., Vasilaki, A., McArdle, F., Griffiths, R. D., . . . Jackson, M. J. (2003). Effect of vitamin C supplements on antioxidant defence and stress proteins in human lymphocytes and skeletal muscle. Journal of Physiology, 549(2), 645-652. doi:10.1113/jphysiol.2003.040303

    DOI: 10.1113/jphysiol.2003.040303

    Exercise, oxidative stress and muscle diseases (Chapter)

    Jackson, M. J., Pattwell, D., & McArdle, A. (2003). Exercise, oxidative stress and muscle diseases. In Z. Radak (Ed.), Exercise and diseases (pp. 51-66). Oxford: Meyer and Meyer Sport (UK) Ltd.

    Ischemia and reperfusion of skeletal muscle lead to the appearance of a stable lipid free radical in the circulation (Journal article)

    Pattwell, D., Ashton, T., McArdle, A., Griffiths, R. D., & Jackson, M. J. (2003). Ischemia and reperfusion of skeletal muscle lead to the appearance of a stable lipid free radical in the circulation. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 284(6), H2400-H2404. doi:10.1152/ajpheart.00931.2002

    DOI: 10.1152/ajpheart.00931.2002

    Ischemia and reperfusion of skeletal muscle lead to the appearance of a stable lipid free radical in the circulation (Journal article)

    Pattwell, D., Ashton, T., McArdle, A., Griffiths, R. D., & Jackson, M. J. (2003). Ischemia and reperfusion of skeletal muscle lead to the appearance of a stable lipid free radical in the circulation. American Journal of Physiology - Heart and Circulatory Physiology, 284(6 53-6).

    Lack of protection of prior heat shock against UV-induced oxidative stress in human skin fibroblasts (Journal article)

    Jones, S. A., McArdle, A., McArdle, F., Jack, C. I. A., & Jackson, M. J. (2003). Lack of protection of prior heat shock against UV-induced oxidative stress in human skin fibroblasts. REDOX REPORT, 8(4), 199-204. doi:10.1179/135100003225002691

    DOI: 10.1179/135100003225002691

    Lack of protection of prior heat shock against UV-induced oxidative stress in human skin fibroblasts (Journal article)

    Jones, S. A., McArdle, A., McArdle, F., Jack, C. I. A., & Jackson, M. J. (2003). Lack of protection of prior heat shock against UV-induced oxidative stress in human skin fibroblasts. Redox Report, 8(4), 199-204.

    Oxidative stress in a novel model of chronic acidosis in LLC-PK1 cells (Journal article)

    Rustom, R., Wang, B. H., McArdle, F., Shalamanova, L., Alexander, J., McArdle, A., . . . Jackson, M. J. (2003). Oxidative stress in a novel model of chronic acidosis in LLC-PK1 cells. NEPHRON EXPERIMENTAL NEPHROLOGY, 95(1), E13-E23. doi:10.1159/000073019

    DOI: 10.1159/000073019

    Skeletal Muscle Ageing (Chapter)

    Broome, C. S., Vasilaki, A., & McArdle, A. (2003). Skeletal Muscle Ageing. In R. Aspinall (Ed.), Aging of Organs and Systems (pp. 73-100). Netherlands: Kluwer Academic Publishers.

    Skeletal muscles of aged male mice fail to adapt following contractile activity (Journal article)

    Vasilaki, A., Iwanejko, L., McArdle, F., Broome, C. S., Jackson, M. J., & McArdle, A. (2003). Skeletal muscles of aged male mice fail to adapt following contractile activity. BIOCHEMICAL SOCIETY TRANSACTIONS, 31, 455-456. doi:10.1042/BST0310455

    DOI: 10.1042/BST0310455

    2002

    Attenuated HSP70 response in skeletal muscle of aged rats following contractile activity (Journal article)

    Vasilaki, A., Jackson, M. J., & McArdle, A. (2002). Attenuated HSP70 response in skeletal muscle of aged rats following contractile activity. MUSCLE & NERVE, 25(6), 902-905. doi:10.1002/mus.10094

    DOI: 10.1002/mus.10094

    Effects of micronutrient supplements on u.v.-induced skin damage (Journal article)

    Jackson, M. J., McArdle, F., Storey, A., Jones, S. A., McArdle, A., & Rhodes, L. E. (2002). Effects of micronutrient supplements on u.v.-induced skin damage. PROCEEDINGS OF THE NUTRITION SOCIETY, 61(2), 187-189. doi:10.1079/PNS2002158

    DOI: 10.1079/PNS2002158

    Exercise and skeletal muscle ageing: cellular and molecular mechanisms (Journal article)

    McArdle, A., Vasilaki, A., & Jackson, M. (2002). Exercise and skeletal muscle ageing: cellular and molecular mechanisms. AGEING RESEARCH REVIEWS, 1(1), 79-93. doi:10.1016/S0047-6374(01)00368-2

    DOI: 10.1016/S0047-6374(01)00368-2

    Ischaemic preconditioning of skeletal muscle 2. Investigation of the potential mechanisms involved. (Journal article)

    Bushell, A. J., Klenerman, L., Davies, H., Grierson, I., McArdle, A., & Jackson, M. J. (2002). Ischaemic preconditioning of skeletal muscle 2. Investigation of the potential mechanisms involved.. The Journal of bone and joint surgery. British volume, 84(8), 1189-1193. doi:10.1302/0301-620x.84b8.9362

    DOI: 10.1302/0301-620x.84b8.9362

    Stress proteins and exercise induced muscle damage (Chapter)

    McArdle, A., & Jackson, M. J. (2002). Stress proteins and exercise induced muscle damage. In M. Locke, & E. Noble (Eds.), Stress proteins and tissue damage (pp. ???). Boca Raton: CRC Press.

    2001

    A fluorescence-based method for measuring nitric oxide in extracts of skeletal muscle. (Journal article)

    Sutherland, H., Khundkar, R., Zolle, O., McArdle, A., Simpson, A. W., Jarvis, J. C., & Salmons, S. (2001). A fluorescence-based method for measuring nitric oxide in extracts of skeletal muscle.. Nitric oxide : biology and chemistry, 5(5), 475-481. doi:10.1006/niox.2001.0374

    DOI: 10.1006/niox.2001.0374

    Adaptation to oxidative stress in ageing (Journal article)

    Jackson, M. J., Spiers, S., & McArdle, A. (2001). Adaptation to oxidative stress in ageing. BIOFACTORS, 15(2-4), 121-122. doi:10.1002/biof.5520150215

    DOI: 10.1002/biof.5520150215

    Contractile activity-induced oxidative stress: Cellular origin and adaptive responses (Journal article)

    McArdle, A., Pattwell, D., Vasilaki, A., Griffiths, R. D., & Jackson, M. J. (2001). Contractile activity-induced oxidative stress: Cellular origin and adaptive responses. American Journal of Physiology - Cell Physiology, 280(3 49-3).

    Contractile activity-induced oxidative stress: cellular origin and adaptive responses (Journal article)

    McArdle, A., Pattwell, D., Vasilaki, A., Griffiths, R. D., & Jackson, M. J. (2001). Contractile activity-induced oxidative stress: cellular origin and adaptive responses. Am J Physiol Cell Physiol, 280(3)(3), C621-C627.

    Contractile activity-induced oxidative stress: cellular origin and adaptive responses (Journal article)

    McArdle, A., Pattwell, D., Vasilaki, A., Griffiths, R. D., & Jackson, M. J. (2001). Contractile activity-induced oxidative stress: cellular origin and adaptive responses. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 280(3), C621-C627. Retrieved from http://gateway.webofknowledge.com/

    Measurement of free radical production by in vivo microdialysis during ischemia/reperfusion injury to skeletal muscle (Journal article)

    Pattwell, D., McArdle, A., Griffiths, R. D., & Jackson, M. J. (2001). Measurement of free radical production by in vivo microdialysis during ischemia/reperfusion injury to skeletal muscle. FREE RADICAL BIOLOGY AND MEDICINE, 30(9), 979-985. doi:10.1016/S0891-5849(01)00485-3

    DOI: 10.1016/S0891-5849(01)00485-3

    Time course of responses of human skeletal muscle to exercise-induced oxidative stress (Journal article)

    Khassaf, M., Child, R. B., McArdle, A., Brodie, D. A., Esanu, C., Griffiths, R. D., & Jackson, M. J. (2001). Time course of responses of human skeletal muscle to exercise-induced oxidative stress. Journal of Applied Physiology, 90(3), 1031-1036.

    Time course of responses of human skeletal muscle to oxidative stress induced by nondamaging exercise (Journal article)

    Khassaf, M., Child, R. B., McArdle, A., Brodie, D. A., Esanu, C., & Jackson, M. J. (2001). Time course of responses of human skeletal muscle to oxidative stress induced by nondamaging exercise. JOURNAL OF APPLIED PHYSIOLOGY, 90(3), 1031-1035. Retrieved from http://gateway.webofknowledge.com/

    2000

    Exercise, oxidative stress and ageing (Journal article)

    McArdle, A., & Jackson, M. J. (2000). Exercise, oxidative stress and ageing. JOURNAL OF ANATOMY, 197, 539-541. doi:10.1046/j.1469-7580.2000.19740539.x

    DOI: 10.1046/j.1469-7580.2000.19740539.x

    Hyperthermia to normal human skin in vivo upregulates heat shock proteins 27, 60, 72i and 90 (Journal article)

    Wilson, N., McArdle, A., Guerin, D., Tasker, H., Wareing, P., Foster, C. S., . . . Rhodes, L. E. (2000). Hyperthermia to normal human skin in vivo upregulates heat shock proteins 27, 60, 72i and 90. JOURNAL OF CUTANEOUS PATHOLOGY, 27(4), 176-182. doi:10.1034/j.1600-0560.2000.027004176.x

    DOI: 10.1034/j.1600-0560.2000.027004176.x

    1999

    Apoptosis in multinucleated skeletal muscle myotubes (Journal article)

    McArdle, A., Maglara, A., Appleton, P., Watson, A. J. M., Grierson, I., & Jackson, M. J. (1999). Apoptosis in multinucleated skeletal muscle myotubes. LABORATORY INVESTIGATION, 79(9), 1069-1076. Retrieved from http://gateway.webofknowledge.com/

    Free radical activity following contraction-induced injury to the extensor digitorum longus muscles of rats (Journal article)

    McArdle, A., van der Meulen, J. H., Catapano, M., Symons, M. C. R., Faulkner, J. A., & Jackson, M. J. (1999). Free radical activity following contraction-induced injury to the extensor digitorum longus muscles of rats. FREE RADICAL BIOLOGY AND MEDICINE, 26(9-10), 1085-1091. doi:10.1016/S0891-5849(98)00317-7

    DOI: 10.1016/S0891-5849(98)00317-7

    In vivo microdialysis - A technique for analysis of chemical activators of muscle pain (Journal article)

    McArdle, A., Khera, G., Edwards, R. H. T., & Jackson, M. J. (1999). In vivo microdialysis - A technique for analysis of chemical activators of muscle pain. MUSCLE & NERVE, 22(8), 1047-1052. doi:3.3.CO;2-H">10.1002/(SICI)1097-4598(199908)22:8<1047::AID-MUS6>3.3.CO;2-H

    DOI: 10.1002/(SICI)1097-4598(199908)22:8<1047::AID-MUS6>3.3.CO;2-H

    1998

    Antioxidant micronutrients and gene expression (Journal article)

    Jackson, M. J., McArdle, A., & McArdle, F. (1998). Antioxidant micronutrients and gene expression. PROCEEDINGS OF THE NUTRITION SOCIETY, 57(2), 301-305. doi:10.1079/PNS19980044

    DOI: 10.1079/PNS19980044

    Effect of propylthiouracil-induced hypothyroidism on the onset of skeletal muscle necrosis in dystrophin-deficient mdx mice (Journal article)

    McArdle, A., Helliwell, T. R., Beckett, G. J., Catapano, M., Davis, A., & Jackson, M. J. (1998). Effect of propylthiouracil-induced hypothyroidism on the onset of skeletal muscle necrosis in dystrophin-deficient mdx mice. CLINICAL SCIENCE, 95(1), 83-89. doi:10.1042/CS19980029

    DOI: 10.1042/CS19980029

    Programmed cell death in skeletal muscle. (Journal article)

    Maglara, A., Jackson, M. J., & McArdle, A. (1998). Programmed cell death in skeletal muscle.. Biochemical Society transactions, 26(3), S259. doi:10.1042/bst026s259

    DOI: 10.1042/bst026s259

    The pathophysiology of Duchenne muscular dystrophy (Journal article)

    McArdle, A., & Jackson, M. J. (1998). The pathophysiology of Duchenne muscular dystrophy. Medical Biochemistry, 1(1), 3-17.

    1997

    Age-related changes in muscle calcium content in dystrophin-deficient mdx mice (Journal article)

    Reeve, J. L., McArdle, A., & Jackson, M. J. (1997). Age-related changes in muscle calcium content in dystrophin-deficient mdx mice. MUSCLE & NERVE, 20(3), 357-360. doi:3.0.CO;2-Y">10.1002/(SICI)1097-4598(199703)20:3<357::AID-MUS14>3.0.CO;2-Y

    DOI: 10.1002/(SICI)1097-4598(199703)20:3<357::AID-MUS14>3.0.CO;2-Y

    Contraction-induced injury to the extensor digitorum longus muscles of rats: the role of vitamin E (Journal article)

    VanderMeulen, J. H., McArdle, A., Jackson, M. J., & Faulkner, J. A. (1997). Contraction-induced injury to the extensor digitorum longus muscles of rats: the role of vitamin E. JOURNAL OF APPLIED PHYSIOLOGY, 83(3), 817-823. Retrieved from http://gateway.webofknowledge.com/

    In vivo model of muscle pain: Quantification of intramuscular chemical, electrical, and pressure changes associated with saline-induced muscle pain in humans (Journal article)

    GravenNielsen, T., McArdle, A., Phoenix, J., ArendtNielsen, L., Jensen, T. S., Jackson, M. J., & Edwards, R. H. T. (1997). In vivo model of muscle pain: Quantification of intramuscular chemical, electrical, and pressure changes associated with saline-induced muscle pain in humans. PAIN, 69(1-2), 137-143. doi:10.1016/S0304-3959(96)03270-8

    DOI: 10.1016/S0304-3959(96)03270-8

    1996

    Exposure risks related to the management of three wound drainage systems. (Journal article)

    Zerbe, M., McArdle, A., & Goldrick, B. (1996). Exposure risks related to the management of three wound drainage systems.. American journal of infection control, 24(5), 346-352. doi:10.1016/s0196-6553(96)90021-8

    DOI: 10.1016/s0196-6553(96)90021-8

    Fasting increases the extent of muscle necrosis in the mdx mouse (Journal article)

    Helliwell, T. R., MacLennan, P. A., McArdle, A., Edwards, R. H. T., & Jackson, M. J. (1996). Fasting increases the extent of muscle necrosis in the mdx mouse. CLINICAL SCIENCE, 90(6), 467-472. doi:10.1042/cs0900467

    DOI: 10.1042/cs0900467

    Heat shock protein 70 expression in skeletal muscle. (Conference Paper)

    McArdle, A., & Jackson, M. J. (1996). Heat shock protein 70 expression in skeletal muscle.. In Biochemical Society transactions Vol. 24 (pp. 485S). doi:10.1042/bst024485s

    DOI: 10.1042/bst024485s

    Investigation by polymerase chain reaction of enteroviral infection in patients with chronic fatigue syndrome (Journal article)

    McArdle, A., McArdle, F., Jackson, M. J., Page, S. F., Fahal, I., & Edwards, R. H. T. (1996). Investigation by polymerase chain reaction of enteroviral infection in patients with chronic fatigue syndrome. CLINICAL SCIENCE, 90(4), 295-300. doi:10.1042/cs0900295

    DOI: 10.1042/cs0900295

    Reported blood exposure rates and staff nurse satisfaction with a closed surgical drainage system. (Journal article)

    Zerbe, M. B., McArdle, A., Goldrick, B., & Francis, M. (1996). Reported blood exposure rates and staff nurse satisfaction with a closed surgical drainage system.. American journal of infection control, 24(3), 190-198. doi:10.1016/s0196-6553(96)90012-7

    DOI: 10.1016/s0196-6553(96)90012-7

    1995

    EFFECTS OF COCAINE ON LEAKAGE OF CREATINE-KINASE FROM SKELETAL-MUSCLE - IN-VITRO AND IN-VIVO STUDIES IN MICE (Journal article)

    BRAZEAU, G. A., MCARDLE, A., & JACKSON, M. J. (1995). EFFECTS OF COCAINE ON LEAKAGE OF CREATINE-KINASE FROM SKELETAL-MUSCLE - IN-VITRO AND IN-VIVO STUDIES IN MICE. LIFE SCIENCES, 57(17), 1569-1578. doi:10.1016/0024-3205(95)02132-3

    DOI: 10.1016/0024-3205(95)02132-3

    HOW DOES DYSTROPHIN DEFICIENCY LEAD TO MUSCLE DEGENERATION - EVIDENCE FROM THE MDX MOUSE (Journal article)

    MCARDLE, A., EDWARDS, R. H. T., & JACKSON, M. J. (1995). HOW DOES DYSTROPHIN DEFICIENCY LEAD TO MUSCLE DEGENERATION - EVIDENCE FROM THE MDX MOUSE. NEUROMUSCULAR DISORDERS, 5(6), 445-456. doi:10.1016/0960-8966(95)00001-4

    DOI: 10.1016/0960-8966(95)00001-4

    1994

    RELEASE OF CREATINE-KINASE AND PROSTAGLANDIN E(2) FROM REGENERATING SKELETAL-MUSCLE FIBERS (Journal article)

    MCARDLE, A., EDWARDS, R. H. T., & JACKSON, M. J. (1994). RELEASE OF CREATINE-KINASE AND PROSTAGLANDIN E(2) FROM REGENERATING SKELETAL-MUSCLE FIBERS. JOURNAL OF APPLIED PHYSIOLOGY, 76(3), 1274-1278. Retrieved from http://gateway.webofknowledge.com/

    TIME-COURSE OF CHANGES IN PLASMA-MEMBRANE PERMEABILITY IN THE DYSTROPHIN-DEFICIENT MDX MOUSE (Journal article)

    MCARDLE, A., EDWARDS, R. H. T., & JACKSON, M. J. (1994). TIME-COURSE OF CHANGES IN PLASMA-MEMBRANE PERMEABILITY IN THE DYSTROPHIN-DEFICIENT MDX MOUSE. MUSCLE & NERVE, 17(12), 1378-1384. doi:10.1002/mus.880171206

    DOI: 10.1002/mus.880171206

    1993

    Role of regenerating muscle fibres in aberrant prostaglandin metabolism by dystrophic muscle tissue. (Conference Paper)

    McArdle, A., Edwards, R. H., & Jackson, M. J. (1993). Role of regenerating muscle fibres in aberrant prostaglandin metabolism by dystrophic muscle tissue.. In Biochemical Society transactions Vol. 21 ( Pt 3) (pp. 301S). doi:10.1042/bst021301s

    DOI: 10.1042/bst021301s

    1992

    ACCUMULATION OF CALCIUM BY NORMAL AND DYSTROPHIN-DEFICIENT MOUSE MUSCLE DURING CONTRACTILE ACTIVITY INVITRO (Journal article)

    MCARDLE, A., EDWARDS, R. H. T., & JACKSON, M. J. (1992). ACCUMULATION OF CALCIUM BY NORMAL AND DYSTROPHIN-DEFICIENT MOUSE MUSCLE DURING CONTRACTILE ACTIVITY INVITRO. CLINICAL SCIENCE, 82(4), 455-459. doi:10.1042/cs0820455

    DOI: 10.1042/cs0820455

    1991

    45Calcium accumulation by isolated muscles from dystrophin-deficient mdx mice (Conference Paper)

    McArdle, A., Edwards, R. H. T., & Jackson, M. J. (1991). 45Calcium accumulation by isolated muscles from dystrophin-deficient mdx mice. In Journal of Physiology Vol. 434.

    Acute effects of phorbol esters on the protein-synthetic rate and carbohydrate metabolism of normal and mdx mouse muscles. (Journal article)

    MacLennan, P. A., McArdle, A., & Edwards, R. H. (1991). Acute effects of phorbol esters on the protein-synthetic rate and carbohydrate metabolism of normal and mdx mouse muscles.. The Biochemical journal, 275 ( Pt 2), 477-483. doi:10.1042/bj2750477

    DOI: 10.1042/bj2750477

    EFFECTS OF CONTRACTILE ACTIVITY ON MUSCLE DAMAGE IN THE DYSTROPHIN-DEFICIENT MDX MOUSE (Journal article)

    MCARDLE, A., EDWARDS, R. H. T., & JACKSON, M. J. (1991). EFFECTS OF CONTRACTILE ACTIVITY ON MUSCLE DAMAGE IN THE DYSTROPHIN-DEFICIENT MDX MOUSE. CLINICAL SCIENCE, 80(4), 367-371. doi:10.1042/cs0800367

    DOI: 10.1042/cs0800367

    Effects of calcium on protein turnover of incubated muscles from mdx mice. (Journal article)

    MacLennan, P. A., McArdle, A., & Edwards, R. H. (1991). Effects of calcium on protein turnover of incubated muscles from mdx mice.. The American journal of physiology, 260(4 Pt 1), E594-E598. doi:10.1152/ajpendo.1991.260.4.e594

    DOI: 10.1152/ajpendo.1991.260.4.e594

    Muscle damage in mdx mice. (Journal article)

    Jackson, M. J., McArdle, A., Edwards, R. H., & Jones, D. A. (1991). Muscle damage in mdx mice.. Nature, 350(6320), 664. doi:10.1038/350664b0

    DOI: 10.1038/350664b0

    Prostaglandin metabolism in dystrophin-deficient MDX mouse muscle. (Conference Paper)

    McArdle, A., Foxley, A., Edwards, R. H., & Jackson, M. J. (1991). Prostaglandin metabolism in dystrophin-deficient MDX mouse muscle.. In Biochemical Society transactions Vol. 19 (pp. 177S). doi:10.1042/bst019177s

    DOI: 10.1042/bst019177s

    1990

    Mdx mouse - Studies of protein degradation in isolated muscles (Conference Paper)

    MacLennan, P. A., McArdle, A., & Edwards, R. H. T. (1990). Mdx mouse - Studies of protein degradation in isolated muscles. In Journal of Physiology Vol. 424.
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