Clinical and Translational Approaches

The Clinical and Translational Approaches research theme in the Institute of Ageing and Chronic Disease is taking inspirational science from the laboratory bench to the bedside.

It applies scientific knowledge to clinical practice, working in collaboration with experts around the world, improving human health and wellbeing nationally and worldwide. One of the keys to our success is the fact that patients can access researchers directly through our disease specific patient groups

Our aim is to find new drugs, devices and treatments to enhance human health. Some of our research projects include:

  • Creating stem cell technology to reverse the effects of limbal tissue failure, a painful blindness caused by injury or inflammation, allowing patients to recover their normal vision
  • Investigating rheumatic diseases, in particular, cellular immunity in rheumatoid arthritis, and systemic sclerosis, which causes abnormal tissue growth, and the rare Behçet’s disease, which inflames tissues and blood vessels
  • Using stem cells from joints to treat arthritis and repair cartilages
  • Finding treatments for diabetic retinopathy and age-related macular degeneration, including revolutionary light-based therapy
  • Repairing joints by using a combination of stem cells and biomaterials
  • Finding new drugs, devices and treatments to enhance human health.

Our work is funded by major funding bodies such as the Wellcome Trust, as well as charities including Fight for Sight. We also have strong industrial and pharmaceutical collaborations throughout the world.